Muscle miRNAs are influenced by sex at baseline and in response to exercise
Sex differences in microRNA (miRNA) expression profiles have been found across multiple tissues. Skeletal muscle is one of the most sex-biased tissues of the body. MiRNAs are necessary for development and have... (Source: BMC Biology)
Source: BMC Biology - November 27, 2023 Category: Biology Authors: Danielle Hiam, Shanie Landen, Macsue Jacques, Sarah Voisin, S éverine Lamon and Nir Eynon Tags: Research article Source Type: research

Different mechanisms of X-ray irradiation-induced male and female sterility in Aedes aegypti
Aedes aegypti (Ae. aegypti) is the major vector that transmits many diseases including dengue, Zika, and filariasis in tropical and subtropical regions. Due to the growing resistance to chemical-based insecticide... (Source: BMC Biology)
Source: BMC Biology - November 27, 2023 Category: Biology Authors: Heng Zhang, Emma Trueman, Xinjun Hou, De Xian Chew, Lu Deng, Jonathan Liew, Tania Chia, Zhiyong Xi, Cheong Huat Tan and Yu Cai Tags: Research article Source Type: research

Author Correction: Genetic evidence of tri-genealogy hypothesis on the origin of ethnic minorities in Yunnan
(Source: BMC Biology)
Source: BMC Biology - November 24, 2023 Category: Biology Authors: Zhaoqing Yang, Hao Chen, Yan Lu, Yang Gao, Hao Sun, Jiucun Wang, Li Jin, Jiayou Chu and Shuhua Xu Tags: Author Correction Source Type: research

Evidence for widespread existence of functional novel and non-canonical human transcripts
Fraction of functional sequence in the human genome remains a key unresolved question in Biology and the subject of vigorous debate. While a plethora of studies have connected a significant fraction of human D... (Source: BMC Biology)
Source: BMC Biology - November 24, 2023 Category: Biology Authors: Dongyang Xu, Lu Tang, Junjun Zhou, Fang Wang, Huifen Cao, Yu Huang and Philipp Kapranov Tags: Research article Source Type: research

The function of wing bullae in mayflies (Insecta: Ephemeroptera) reveals new insights into the early evolution of Pterygota
Mayflies are basal winged insects of crucial importance for the understanding of the early evolution of Pterygota. Unlike all other insects, they have two successive winged stages, the subimago and the imago. ... (Source: BMC Biology)
Source: BMC Biology - November 23, 2023 Category: Biology Authors: Eduardo Dom ínguez, Thomas van de Kamp, István Mikó, M. Gabriela Cuezzo and Arnold H. Staniczek Tags: Research article Source Type: research

Benchmarking MicrobIEM – a user-friendly tool for decontamination of microbiome sequencing data
Microbiome analysis is becoming a standard component in many scientific studies, but also requires extensive quality control of the 16S rRNA gene sequencing data prior to analysis. In particular, when investig... (Source: BMC Biology)
Source: BMC Biology - November 23, 2023 Category: Biology Authors: Claudia H ülpüsch, Luise Rauer, Thomas Nussbaumer, Vera Schwierzeck, Madhumita Bhattacharyya, Veronika Erhart, Claudia Traidl-Hoffmann, Matthias Reiger and Avidan U. Neumann Tags: Research article Source Type: research

Convergent evolution of the sensory pits in and within flatworms
Unlike most free-living platyhelminths, catenulids, the sister group to all remaining flatworms, do not have eyes. Instead, the most prominent sensory structures in their heads are statocysts or sensory pits. ... (Source: BMC Biology)
Source: BMC Biology - November 22, 2023 Category: Biology Authors: Ludwik G ąsiorowski, Isabel Lucia Dittmann, Jeremias N. Brand, Torben Ruhwedel, Wiebke Möbius, Bernhard Egger and Jochen C. Rink Tags: Research article Source Type: research

A pangenome graph reference of 30 chicken genomes allows genotyping of large and complex structural variants
The red junglefowl, the wild outgroup of domestic chickens, has historically served as a reference for genomic studies of domestic chickens. These studies have provided insight into the etiology of traits of c... (Source: BMC Biology)
Source: BMC Biology - November 22, 2023 Category: Biology Authors: Edward S. Rice, Antton Alberdi, James Alfieri, Giridhar Athrey, Jennifer R. Balacco, Philippe Bardou, Heath Blackmon, Mathieu Charles, Hans H. Cheng, Olivier Fedrigo, Steven R. Fiddaman, Giulio Formenti, Laurent A. F. Frantz, M. Thomas P. Gilbert, Cari J. Tags: Research article Source Type: research

Tissue-specific temperature dependence of RNA editing levels in zebrafish
RNA editing by adenosine deaminase acting on RNA (ADAR) occurs in all metazoans and fulfils several functions. Here, we examined effects of acclimation temperature (27 °C, 18 °C,13 °C) on editing patterns in six ... (Source: BMC Biology)
Source: BMC Biology - November 20, 2023 Category: Biology Authors: Wenhao Li, Mengdi Bu, Ruiqin Hu, Shouwen Jiang, Liangbiao Chen and George N. Somero Tags: Research article Source Type: research

Genome-wide expression QTL mapping reveals the highly dynamic regulatory landscape of a major wheat pathogen
In agricultural ecosystems, outbreaks of diseases are frequent and pose a significant threat to food security. A successful pathogen undergoes a complex and well-timed sequence of regulatory changes to avoid d... (Source: BMC Biology)
Source: BMC Biology - November 20, 2023 Category: Biology Authors: Leen Nanchira Abraham and Daniel Croll Tags: Research article Source Type: research

Cellular reprogramming is driven by widespread rewiring of promoter-enhancer interactions
Long-range interactions between promoters and cis-regulatory elements, such as enhancers, play critical roles in gene regulation. However, the role of three-dimensional (3D) chromatin structure in orchestrating c... (Source: BMC Biology)
Source: BMC Biology - November 20, 2023 Category: Biology Authors: Miao Wang, Bing He, Yueling Hao, Divyaa Srinivasan, Jatin Shrinet and Peter Fraser Tags: Research article Source Type: research

Unraveling the complex evolutionary history of lepidopteran chromosomes through ancestral chromosome reconstruction and novel chromosome nomenclature
Lepidoptera is one of the most species-rich animal groups, with substantial karyotype variations among species due to chromosomal rearrangements. Knowledge of the evolutionary patterns of lepidopteran chromoso... (Source: BMC Biology)
Source: BMC Biology - November 20, 2023 Category: Biology Authors: Xi Chen, Zuoqi Wang, Chaowei Zhang, Jingheng Hu, Yueqi Lu, Hang Zhou, Yang Mei, Yuyang Cong, Fangyuan Guo, Yaqin Wang, Kang He, Ying Liu and Fei Li Tags: Research article Source Type: research

The meaning of ubiquitylation of the DSL ligand Delta for the development of Drosophila
Ubiquitylation (ubi) of the intracellular domain of the Notch ligand Delta (Dl) by the E3 ligases Neuralized (Neur) and Mindbomb1 (Mib1) on lysines (Ks) is thought to be essential for the its signalling activi... (Source: BMC Biology)
Source: BMC Biology - November 16, 2023 Category: Biology Authors: Tobias Troost, Ekaterina Seib, Alina Airich, Nicole V üllings, Aleksandar Necakov, Stefano De Renzis and Thomas Klein Tags: Research article Source Type: research

Author Correction: A protocol for adding knowledge to Wikidata: aligning resources on human coronaviruses
(Source: BMC Biology)
Source: BMC Biology - November 16, 2023 Category: Biology Authors: Andra Waagmeester, Egon L. Willighagen, Andrew I. Su, Martina Kutmon, Jose Emilio Labra Gayo, Daniel Fern ández-Álvarez, Quentin Groom, Peter J. Schaap, Lisa M. Verhagen and Jasper J. Koehorst Tags: Author Correction Source Type: research

The divergent ER-mitochondria encounter structures (ERMES) are conserved in parabasalids but lost in several anaerobic lineages with hydrogenosomes
The endoplasmic reticulum (ER)-mitochondria membrane contact sites (MCS) are extensively studied in aerobic eukaryotes; however, little is known about MCS in anaerobes with reduced forms of mitochondria named ... (Source: BMC Biology)
Source: BMC Biology - November 15, 2023 Category: Biology Authors: Jitka Ku čerová, Alois Zdrha, Abhishek Shinde, Karel Harant, Ivan Hrdý and Jan Tachezy Tags: Research article Source Type: research