Taste receptor type 1 member 3 enables western diet-induced anxiety in mice
Accumulating evidence supports that the Western diet (WD), a diet high in saturated fat and sugary drinks, contributes to the pathogenesis of anxiety disorders, which are the most prevalent mental disorders wo... (Source: BMC Biology)
Source: BMC Biology - November 6, 2023 Category: Biology Authors: Jae Won Song, Keon-Hee Lee, Hobin Seong, Dong-Mi Shin and Woo-Jeong Shon Tags: Research article Source Type: research
Expression divergence of expansin genes drive the heteroblasty in Ceratopteris chingii
Sterile-fertile heteroblasty is a common phenomenon observed in ferns, where the leaf shape of a fern sporophyll, responsible for sporangium production, differs from that of a regular trophophyll. However, due... (Source: BMC Biology)
Source: BMC Biology - November 6, 2023 Category: Biology Authors: Yue Zhang, Yves Van de Peer, Bei Lu, Sisi Zhang, Jingru Che, Jinming Chen, Kathleen Marchal and Xingyu Yang Tags: Research article Source Type: research
Two zinc finger proteins, VdZFP1 and VdZFP2, interact with VdCmr1 to promote melanized microsclerotia development and stress tolerance in Verticillium dahliae
Melanin plays important roles in morphological development, survival, host –pathogen interactions and in the virulence of phytopathogenic fungi. In Verticillum dahliae, increases in melanin are recognized as marke... (Source: BMC Biology)
Source: BMC Biology - October 31, 2023 Category: Biology Authors: Huan Li, Ruo-Cheng Sheng, Chen-Ning Zhang, Li-Chao Wang, Min Li, Ya-Hong Wang, Yu-Hang Qiao, Steven J. Klosterman, Jie-Yin Chen, Zhi-Qiang Kong, Krishna V. Subbarao, Feng-Mao Chen and Dan-Dan Zhang Tags: Research article Source Type: research
TPpred-LE: therapeutic peptide function prediction based on label embedding
Therapeutic peptides play an essential role in human physiology, treatment paradigms and bio-pharmacy. Several computational methods have been developed to identify the functions of therapeutic peptides based ... (Source: BMC Biology)
Source: BMC Biology - October 31, 2023 Category: Biology Authors: Hongwu Lv, Ke Yan and Bin Liu Tags: Methodology article Source Type: research
PFTK1 kinase regulates axogenesis during development via RhoA activation
PFTK1/Eip63E is a member of the cyclin-dependent kinases (CDKs) family and plays an important role in normal cell cycle progression. Eip63E expresses primarily in postnatal and adult nervous system in Drosophila ... (Source: BMC Biology)
Source: BMC Biology - October 31, 2023 Category: Biology Authors: Yasmilde Rodr íguez González, Fatemeh Kamkar, Paymaan Jafar-nejad, Suzi Wang, Dianbo Qu, Leticia Sanchez Alvarez, Dina Hawari, Margaret Sonnenfeld, Ruth S. Slack, Paul R. Albert, David S. Park and Alvin Joselin Tags: Research article Source Type: research
Diurnal oscillations of epigenetic modifications are associated with variation in rhythmic expression of homoeologous genes in Brassica napus
Epigenetic modifications that exhibit circadian oscillations also promote circadian oscillations of gene expression. Brassica napus is a heterozygous polyploid species that has undergone distant hybridization and... (Source: BMC Biology)
Source: BMC Biology - October 31, 2023 Category: Biology Authors: Zhifei Xue, Baibai Gao, Guoting Chen, Jie Liu, Weizhi Ouyang, Mohamed Frahat Foda, Qing Zhang, Xiwen Zhang, Wei Zhang, Mingyue Guo, Xingwang Li and Bin Yi Tags: Research article Source Type: research
Lactoferrin deficiency during lactation increases the risk of depressive-like behavior in adult mice
Lactoferrin is an active protein in breast milk that plays an important role in the growth and development of infants and is implicated as a neuroprotective agent. The incidence of depression is currently incr... (Source: BMC Biology)
Source: BMC Biology - October 31, 2023 Category: Biology Authors: Wenli Wang, Zhimei Cheng, Xiong Wang, Qin An, Kunlun Huang, Yunping Dai, Qingyong Meng and Yali Zhang Tags: Research article Source Type: research
Agarose spot migration assay to measure the chemoattractant potential of extracellular vesicles: applications in regenerative medicine and cancer metastasis
The recruitment of effector cells is one of the novel functions described for extracellular vesicles (EVs) that needs further study. For instance, cell recruitment by mesenchymal stromal cell derived-EVs (MSC-... (Source: BMC Biology)
Source: BMC Biology - October 26, 2023 Category: Biology Authors: Marta Clos-Sansalvador, Marta Mongui ó-Tortajada, Ferran Grau-Leal, Vicenç Ruiz de Porras, Sergio G. Garcia, Marta Sanroque-Muñoz, Miriam Font-Morón, Marcella Franquesa and Francesc E. Borràs Tags: Methodology article Source Type: research
Uncovering the history of recombination and population structure in western Canadian stripe rust populations through mating type alleles
The population structure of crop pathogens such as Puccinia striiformis f. sp. tritici (Pst), the cause of wheat stripe rust, is of interest to researchers looking to understand these pathogens on a molecular lev... (Source: BMC Biology)
Source: BMC Biology - October 25, 2023 Category: Biology Authors: Samuel Holden, Guus Bakkeren, John Hubensky, Ramandeep Bamrah, Mehrdad Abbasi, Dinah Qutob, Mei-Lan de Graaf, Sang Hu Kim, Hadley R. Kutcher, Brent D. McCallum, Harpinder S. Randhawa, Muhammad Iqbal, Keith Uloth, Rishi R. Burlakoti and Gurcharn S. Brar Tags: Research article Source Type: research
Contaminants from dredged sediments alter the transcriptome of Manila clam and induce shifts in microbiota composition
The reuse of dredged sediments in ports and lagoons is a big issue as it should not affect the quality and the equilibrium of ecosystems. In the lagoon of Venice, sediment management is of crucial importance a... (Source: BMC Biology)
Source: BMC Biology - October 25, 2023 Category: Biology Authors: Ilaria Bernardini, Andrea Quagliariello, Luca Peruzza, Maria Elena Martino, Giulia Dalla Rovere, Silvia Iori, Davide Asnicar, Maria Ciscato, Jacopo Fabrello, Fabiana Corami, Martina Cecchetto, Elisa Giubilato, Claudio Carrer, Cinzia Bettiol, Elena Semenzi Tags: Research article Source Type: research
Unveiling adcyap1 as a protective factor linking pain and nerve regeneration through single-cell RNA sequencing of rat dorsal root ganglion neurons
Severe peripheral nerve injury (PNI) often leads to significant movement disorders and intractable pain. Therefore, promoting nerve regeneration while avoiding neuropathic pain is crucial for the clinical trea... (Source: BMC Biology)
Source: BMC Biology - October 25, 2023 Category: Biology Authors: Qi Chen, Xi-Yin Zhang, Yu-Pu Wang, Yun-Jie Fu, Feng Cao, Yi-Nuo Xu, Jin-Ge Kong, Na-Xi Tian, Yu Xu and Yun Wang Tags: Research article Source Type: research
Prevalent bee venom genes evolved before the aculeate stinger and eusociality
Venoms, which have evolved numerous times in animals, are ideal models of convergent trait evolution. However, detailed genomic studies of toxin-encoding genes exist for only a few animal groups. The hyper-div... (Source: BMC Biology)
Source: BMC Biology - October 23, 2023 Category: Biology Authors: Ivan Koludarov, Mariana Velasque, Tobias Senoner, Thomas Timm, Carola Greve, Alexander Ben Hamadou, Deepak Kumar Gupta, G ünter Lochnit, Michael Heinzinger, Andreas Vilcinskas, Rosalyn Gloag, Brock A. Harpur, Lars Podsiadlowski, Burkhard Rost, Timothy N. Tags: Research article Source Type: research
Directional selection coupled with kin selection favors the establishment of senescence
Conventional wisdom in evolutionary theory considers aging as a non-selected byproduct of natural selection. Based on this, conviction aging was regarded as an inevitable phenomenon. It was also thought that i... (Source: BMC Biology)
Source: BMC Biology - October 23, 2023 Category: Biology Authors: Andr ás Szilágyi, Tamás Czárán, Mauro Santos and Eörs Szathmáry Tags: Research article Source Type: research
SRSF2 is required for mRNA splicing during spermatogenesis
RNA splicing plays significant roles in fundamental biological activities. However, our knowledge about the roles of alternative splicing and underlying mechanisms during spermatogenesis is limited. (Source: BMC Biology)
Source: BMC Biology - October 23, 2023 Category: Biology Authors: Wen-Long Lei, Zongchang Du, Tie-Gang Meng, Ruibao Su, Yuan-Yuan Li, Wenbo Liu, Si-Min Sun, Meng-Yu Liu, Yi Hou, Chun-Hui Zhang, Yaoting Gui, Heide Schatten, Zhiming Han, Chenli Liu, Fei Sun, Zhen-Bo Wang & hellip; Tags: Research article Source Type: research
Versatile generation of precise gene edits in bovines using SEGCPN
Gene knockout and knock-in have been widely performed in large farm animals based on genome editing systems. However, many types of precise gene editing, including targeted deletion, gene tagging, and large ge... (Source: BMC Biology)
Source: BMC Biology - October 20, 2023 Category: Biology Authors: Ming Wang, Fangrong Ding, Haiping Wang, Ling Li, Yunping Dai, ZhaoLin Sun and Ning Li Tags: Research article Source Type: research
