Expanded olfactory system in ray-finned fishes capable of terrestrial exploration
Smell abilities differ greatly among vertebrate species due to distinct sensory needs, with exceptional variability reported in the number of olfactory genes and the size of the odour-processing regions of the... (Source: BMC Biology)
Source: BMC Biology - July 31, 2023 Category: Biology Authors: Demian Burguera, Francesco Dionigi, Kristina Kverkov á, Sylke Winkler, Thomas Brown, Martin Pippel, Yicheng Zhang, Maxwell Shafer, Annika L. A. Nichols, Eugene Myers, Pavel Němec and Zuzana Musilova Tags: Research article Source Type: research

Population transcriptogenomics highlights impaired metabolism and small population sizes in tree frogs living in the Chernobyl Exclusion Zone
Individual functional modifications shape the ability of wildlife populations to cope with anthropogenic environmental changes. But instead of adaptive response, human-altered environments can generate a succe... (Source: BMC Biology)
Source: BMC Biology - July 31, 2023 Category: Biology Authors: Cl ément Car, André Gilles, Elen Goujon, Marie-Laure Delignette Muller, Luc Camoin, Sandrine Frelon, Pablo Burraco, Samuel Granjeaud, Emilie Baudelet, Stéphane Audebert, Germán Orizaola, Jean Armengaud, Arthur Tenenhaus, Imène Garali, Jean-Marc Bonzo Tags: Research article Source Type: research

Genome-wide chromatin accessibility landscape and dynamics of transcription factor networks during ovule and fiber development in cotton
The development of cotton fiber is regulated by the orchestrated binding of regulatory proteins to cis-regulatory elements associated with developmental genes. The cis –trans regulatory dynamics occurred throughou... (Source: BMC Biology)
Source: BMC Biology - July 31, 2023 Category: Biology Authors: Yu Bao, Yangyang Wei, Yuling Liu, Jingjing Gao, Shuang Cheng, Guanqing Liu, Qi You, Peng Liu, Quanwei Lu, Pengtao Li, Shulin Zhang, Nan Hu, Yangshuo Han, Shuo Liu, Yuechao Wu, Qingqing Yang & hellip; Tags: Research article Source Type: research

Stressful environments favor deceptive alternative mating tactics to become dominant
Deceptive alternative mating tactics are commonly maintained at low frequencies within populations because males using them are less competitive and acquire lower fitness than those using dominant tactics. How... (Source: BMC Biology)
Source: BMC Biology - July 27, 2023 Category: Biology Authors: Maria J. Albo, Camila Pav ón-Peláez, Mauro Martínez Villar, Bruno A. Buzatto and Ivanna Tomasco Tags: Research article Source Type: research

Differential subgenome expression underlies biomass accumulation in allotetraploid Pennisetum giganteum
Pennisetum giganteum (AABB, 2n  = 4x = 28) is a C4 plant in the genus Pennisetum with origin in Africa but currently also grown in Asia and America. It is a crucial forage and potential energy grass with significa... (Source: BMC Biology)
Source: BMC Biology - July 21, 2023 Category: Biology Authors: Longsheng Xing, Meijia Wang, Qiang He, Hongyu Zhang, Hanfei Liang, Qinghong Zhou, Yu Liu, Ze Liu, Yu Wang, Cailian Du, Yao Xiao, Jianan Liu, Wei Li, Guixia Liu and Huilong Du Tags: Research article Source Type: research

Identification of cell subpopulations associated with disease phenotypes from scRNA-seq data using PACSI
Single-cell RNA sequencing (scRNA-seq) has revolutionized the transcriptomics field by advancing analyses from tissue-level to cell-level resolution. Despite the great advances in the development of computatio... (Source: BMC Biology)
Source: BMC Biology - July 19, 2023 Category: Biology Authors: Chonghui Liu, Yan Zhang, Xin Gao and Guohua Wang Tags: Methodology article Source Type: research

Lessons from discovery of true ADAR RNA editing sites in a human cell line
Conversion or editing of adenosine (A) into inosine (I) catalyzed by specialized cellular enzymes represents one of the most common post-transcriptional RNA modifications with emerging connection to disease. A... (Source: BMC Biology)
Source: BMC Biology - July 19, 2023 Category: Biology Authors: Fang Wang, Huifen Cao, Qiu Xia, Ziheng Liu, Ming Wang, Fan Gao, Dongyang Xu, Bolin Deng, Yong Diao and Philipp Kapranov Tags: Research article Source Type: research

Increased prime edit rates in KCNQ2 and SCN1A via single nicking all-in-one plasmids
Prime editing (PE) is the most recent gene editing technology able to introduce targeted alterations to the genome, including single base pair changes, small insertions, and deletions. Several improvements to ... (Source: BMC Biology)
Source: BMC Biology - July 13, 2023 Category: Biology Authors: N. Dirkx, Wout J. Weuring, E. De Vriendt, N. Smal, J. van de Vondervoort, Ruben van ’t Slot, M. Koetsier, N. Zonnekein, Tim De Pooter, S. Weckhuysen and B. P. C. Koeleman Tags: Research article Source Type: research

Hybridisation has shaped a recent radiation of grass-feeding aphids
Aphids are common crop pests. These insects reproduce by facultative parthenogenesis involving several rounds of clonal reproduction interspersed with an occasional sexual cycle. Furthermore, clonal aphids giv... (Source: BMC Biology)
Source: BMC Biology - July 13, 2023 Category: Biology Authors: Thomas C. Mathers, Roland H. M. Wouters, Sam T. Mugford, Roberto Biello, Cock van Oosterhout and Saskia A. Hogenhout Tags: Research article Source Type: research

Identification of residues critical for the extension of Munc18-1 domain 3a
Neurotransmitter release depends on the fusion of synaptic vesicles with the presynaptic membrane and is mainly mediated by SNARE complex assembly. During the transition of Munc18-1/Syntaxin-1 to the SNARE com... (Source: BMC Biology)
Source: BMC Biology - July 13, 2023 Category: Biology Authors: Xianping Wang, Jihong Gong, Le Zhu, Huidan Chen, Ziqi Jin, Xiaoqiang Mo, Shen Wang, Xiaofei Yang and Cong Ma Tags: Research article Source Type: research

A new compact adenine base editor generated through deletion of HNH and REC2 domain of SpCas9
Adenine base editors (ABEs) are promising therapeutic gene editing tools that can efficiently convert targeted A •T to G•C base pairs in the genome. However, the large size of commonly used ABEs based on SpCas9... (Source: BMC Biology)
Source: BMC Biology - July 11, 2023 Category: Biology Authors: Yuqiang Qian, Di Wang, Wenchao Niu, Ding Zhao, Jinze Li, Zhiquan Liu, Xun Gao, Yang Han, Liangxue Lai and Zhanjun Li Tags: Research article Source Type: research

Enhanced tyrosine sulfation is associated with chronic kidney disease-related atherosclerosis
Chronic kidney disease (CKD) accelerates atherosclerosis, but the mechanisms remain unclear. Tyrosine sulfation has been recognized as a key post-translational modification (PTM) in regulation of various cellu... (Source: BMC Biology)
Source: BMC Biology - July 10, 2023 Category: Biology Authors: Daopeng Dai, Zhengbin Zhu, Hui Han, Tian Xu, Shuo Feng, Wenli Zhang, Fenghua Ding, Ruiyan Zhang and Jinzhou Zhu Tags: Research article Source Type: research

Sensing and avoiding sick conspecifics requires G αi2+ vomeronasal neurons
Rodents utilize chemical cues to recognize and avoid other conspecifics infected with pathogens. Infection with pathogens and acute inflammation alter the repertoire and signature of olfactory stimuli emitted ... (Source: BMC Biology)
Source: BMC Biology - July 10, 2023 Category: Biology Authors: Jan Weiss, H élène Vacher, Anne-Charlotte Trouillet, Trese Leinders-Zufall, Frank Zufall and Pablo Chamero Tags: Research article Source Type: research

Costs of reproduction are present but latent in eusocial bumblebee queens
The standard evolutionary theory of ageing proposes that ageing occurs because of a trade-off between reproduction and longevity. Eusocial insect queens exhibit positive fecundity-longevity associations and so... (Source: BMC Biology)
Source: BMC Biology - July 10, 2023 Category: Biology Authors: David H. Collins, David C. Prince, Jenny L. Donelan, Tracey Chapman and Andrew F. G. Bourke Tags: Research article Source Type: research

High-throughput characterization of cortical microtubule arrays response to anisotropic tensile stress
Plants can perceive and respond to mechanical signals. For instance, cortical microtubule (CMT) arrays usually reorganize following the predicted maximal tensile stress orientation at the cell and tissue level... (Source: BMC Biology)
Source: BMC Biology - July 10, 2023 Category: Biology Authors: Elsa Demes and St éphane Verger Tags: Methodology article Source Type: research