Clinical Images: Erosive tophaceous gout and uric acid nephrolithiasis: microscopic and three ‐dimensional high‐resolution peripheral quantitative computed tomography findings
(Source: Arthritis and Rheumatology)
Source: Arthritis and Rheumatology - February 29, 2024 Category: Rheumatology Authors: Giovanni Adami, Francesca Ruzzon, Angelo Fassio, Davide Gatti, Matteo Gatti, Maurizio Rossini Tags: Clinical Image Source Type: research

VEXAS ‐Defining UBA1 Somatic Variants in 245,368 Diverse Individuals in the NIH All Of Us Cohort
ConclusionWe report the largest cohort to date of persons with the VEXAS-associated p.Met41Leu somatic variant. This cohort differed substantially from reported cohorts of patients with clinical VEXAS, having a higher proportion of persons who were young, female, and of diverse ancestry. Variant allele fractions were lower than reported in clinical VEXAS cohorts, and bioinformatic analysis detected no clinical manifestations of VEXAS. Thus, theUBA1 p.Met41Leu somatic variant displayed incomplete penetrance for VEXAS. Further study is needed to determine the natural history of VEXAS-associated somatic variants in the predis...
Source: Arthritis and Rheumatology - February 29, 2024 Category: Rheumatology Authors: Robert W. Corty, James Brogan, Kevin Byram, Jason Springer, Peter C. Grayson, Alexander G. Bick Tags: Brief Report Source Type: research

Clinical Connections
(Source: Arthritis and Rheumatology)
Source: Arthritis and Rheumatology - February 28, 2024 Category: Rheumatology Tags: Clinical Connections Source Type: research

In This Issue
(Source: Arthritis and Rheumatology)
Source: Arthritis and Rheumatology - February 28, 2024 Category: Rheumatology Tags: In This Issue Source Type: research

Journal Club
(Source: Arthritis and Rheumatology)
Source: Arthritis and Rheumatology - February 28, 2024 Category: Rheumatology Tags: Journal Club Source Type: research

Issue Information
(Source: Arthritis and Rheumatology)
Source: Arthritis and Rheumatology - February 28, 2024 Category: Rheumatology Tags: Issue Information Source Type: research

Strength Training Is Associated With Less Knee Osteoarthritis: Data From the Osteoarthritis Initiative
ConclusionStrength training is beneficial for future knee health, counteracting long-held assumptions that strength training has adverse effects. (Source: Arthritis and Rheumatology)
Source: Arthritis and Rheumatology - February 28, 2024 Category: Rheumatology Authors: Grace H. Lo, Michael J. Richard, Timothy E. McAlindon, Andrea M. Kriska, Lori Lyn Price, Bonny Rockette ‐Wagner, Charles B. Eaton, Marc C. Hochberg, C. Kent Kwoh, Michael C. Nevitt, Jeffrey B. Driban Tags: Full Length Source Type: research

Clinical Connections
(Source: Arthritis and Rheumatology)
Source: Arthritis and Rheumatology - February 28, 2024 Category: Rheumatology Tags: Clinical Connections Source Type: research

In This Issue
(Source: Arthritis and Rheumatology)
Source: Arthritis and Rheumatology - February 28, 2024 Category: Rheumatology Tags: In This Issue Source Type: research

Journal Club
(Source: Arthritis and Rheumatology)
Source: Arthritis and Rheumatology - February 28, 2024 Category: Rheumatology Tags: Journal Club Source Type: research

Issue Information
(Source: Arthritis and Rheumatology)
Source: Arthritis and Rheumatology - February 28, 2024 Category: Rheumatology Tags: Issue Information Source Type: research

Reply
(Source: Arthritis and Rheumatology)
Source: Arthritis and Rheumatology - February 28, 2024 Category: Rheumatology Authors: Richard Moore, Ting Wang, Marina Barguil Mac êdo, Christian Lood Tags: Letter Source Type: research