Reply
(Source: Arthritis and Rheumatology)
Source: Arthritis and Rheumatology - February 23, 2024 Category: Rheumatology Authors: Jill Buyon,
Peter Izmirly,
Mala Masson,
Philip Carlucci,
Caroline G. Izmirly,
Robert Clancy,
Bettina Cuneo Tags: Letters Source Type: research
Clinical Characteristics and Outcomes of Polyarteritis Nodosa: An International Study
ConclusionThe spectrum of PAN remains a complex, multifaceted disease. Relapse is common. Age ≥65 years and serum creatinine>140 μmol/L at diagnosis, as well as gastrointestinal and CNS involvement, are independent predictors of death in sPAN. (Source: Arthritis and Rheumatology)
Source: Arthritis and Rheumatology - February 22, 2024 Category: Rheumatology Authors: Omer Karadag,
Ertugrul Cagri Bolek,
Gizem Ayan,
Aladdin J. Mohammad,
Peter C. Grayson,
Christian Pagnoux,
Eduardo Mart ín‐Nares,
Sara Monti,
Yoshiyuki Abe,
Federico Alberici,
Fatma Alibaz‐Oner,
David Cuthbertson,
Lorenzo Dagna,
Haner Dir Tags: Full Length Source Type: research
Declining Incidence of Systemic Lupus Erythematosus in Norway 1999 –2017: Data From a Population Cohort Identified by International Classification of Diseases, 10th Revision Code and Verified by Classification
ConclusionIn a presumably complete population-based cohort, we identified decreasing incidence of SLE, especially among female persons 50 to 59 years old. Although reasons for declining incidence are not clear, ecological data indicate a possible role of environmental factors, for example, menopausal hormone treatments. (Source: Arthritis and Rheumatology)
Source: Arthritis and Rheumatology - February 22, 2024 Category: Rheumatology Authors: Hilde Haukeland,
Sigrid R. Moe,
Cathrine Brunborg,
Antonela Botea,
Nenad Damjanic,
Gro Å. Wivestad,
Heidi K. Øvreås,
Thea B. Bøe,
Anniken Orre,
Torhild Garen,
Øyvind Molberg,
Karoline Lerang Tags: Full Length Source Type: research
Reply
(Source: Arthritis and Rheumatology)
Source: Arthritis and Rheumatology - February 21, 2024 Category: Rheumatology Authors: Medha Barbhaiya,
Stephane Zuily,
Alison Hendry,
Florian Manneville,
Francis Guillemin,
Karen Costenbader,
Doruk Erkan Tags: Letters Source Type: research
Vitamin D and Marine n ‐3 Fatty Acids for Autoimmune Disease Prevention: Outcomes Two Years After Completion of a Double‐Blind, Placebo‐Controlled Trial
ConclusionTwo years after trial termination, the protective effects of 2000 IU/day of vitamin D dissipated, but 1,000 mg/day of n-3 fatty acids had a sustained effect in reducing AD incidence. (Source: Arthritis and Rheumatology)
Source: Arthritis and Rheumatology - February 20, 2024 Category: Rheumatology Authors: Karen H. Costenbader,
Nancy R. Cook,
I ‐Min Lee,
Jill Hahn,
Joseph Walter,
Vadim Bubes,
Gregory Kotler,
Nicole Yang,
Sonia Friedman,
Erik K. Alexander,
JoAnn E. Manson Tags: Full Length Source Type: research
Hydroxychloroquine in Lupus Pregnancy and Risk of Preeclampsia
ConclusionUsing a large insurance-based database, we did not observe a decreased risk of preeclampsia associated with HCQ treatment in pregnancy, although we cannot rule out residual and unmeasured confounding and misclassification. Further studies leveraging large population-based data and prospective collection could characterize how HCQ influences preeclampsia risk in pregnant patients with SLE and among persons at greater risk of hypertensive disorders of pregnancy. (Source: Arthritis and Rheumatology)
Source: Arthritis and Rheumatology - February 20, 2024 Category: Rheumatology Authors: Amadeia Rector,
Ivana Mari ć,
Yashaar Chaichian,
Eliza Chakravarty,
Miranda Cantu,
Michael H. Weisman,
Gary M Shaw,
Maurice L. Druzin,
Julia F. Simard Tags: Full Length Source Type: research
A multilayered post ‐GWAS analysis pipeline defines functional variants and target genes for systemic lupus erythematosus (SLE)
ConclusionWe demonstrate and validate post-GWAS strategies for utilizing multi-dimensional data to prioritize likely causal variants with cognate gene targets underlying SLE pathogenesis. Our results provide a catalog of significantly SLE-associated SNPs and loci, target genes, and likely biochemical mechanisms, to guide experimental characterization. (Source: Arthritis and Rheumatology)
Source: Arthritis and Rheumatology - February 19, 2024 Category: Rheumatology Authors: Mehdi Fazel ‐Najafabadi,
Loren L. Looger,
Harikrishna Reddy Rallabandi,
Swapan K. Nath Tags: Full Length Source Type: research
Intra ‐Articular Mineralization on Knee CT and Risk of Cartilage Damage: The Multicenter Osteoarthritis Study
CONCLUSIONSCT-detected IA mineralization in the cartilage was associated with higher risk of MRI cartilage worsening in the same compartment and subregion over two years. These findings suggest potential localized, tissue-specific effects of IA mineralization on cartilage pathology in knee OA. (Source: Arthritis and Rheumatology)
Source: Arthritis and Rheumatology - February 19, 2024 Category: Rheumatology Authors: Jean W. Liew,
Mohammed Jarraya,
Ali Guermazi,
David Felson,
Michael Nevitt,
Cora E. Lewis,
James Torner,
Frank W. Roemer,
Michel D. Crema,
Na Wang,
Gabriela Rabasa,
Fabio Becce,
Tristan Pascart,
Tuhina Neogi Tags: Full Length Source Type: research
