DNA Damage and Cellular Senescence in Osteoarthritis: An Unexpected Role for Interferon Regulatory Factor 1 in Chondrocyte DNA Repair
(Source: Arthritis and Rheumatology)
Source: Arthritis and Rheumatology - February 12, 2024 Category: Rheumatology Authors: Brian O. Diekman, Richard F. Loeser Tags: Editorial Source Type: research

Clinical Characteristics and Outcomes of Polyarteritis Nodosa – an International Study
ConclusionThe spectrum of PAN remains a complex, multi-faceted disease. Relapse is common. Age ≥ 65 years and serum creatinine>140 μmol/L at diagnosis, gastrointestinal and CNS involvement are independent predictors of mortality in sPAN. (Source: Arthritis and Rheumatology)
Source: Arthritis and Rheumatology - February 12, 2024 Category: Rheumatology Authors: Omer Karadag, Ertugrul Cagri Bolek, Gizem Ayan, Aladdin J Mohammad, Peter C. Grayson, Christian Pagnoux, Eduardo Mart ín‐Nares, Sara Monti, Yoshiyuki Abe, Federico Alberici, Fatma Alibaz‐Oner, David Cuthbertson, Lorenzo Dagna, Haner Dire Tags: Full Length Source Type: research

Programmed Death Ligand 1 –Expressing Macrophages and Their Protective Role in the Joint During Arthritis
ConclusionPD-L1+ macrophages with efferocytotic and anti-inflammatory characteristics protect the synovium from severe arthritis in the CIA mouse model. Tissue-protective, PD-L1 –expressing macrophages are also present in the human synovium at homeostasis and during rheumatoid arthritis. (Source: Arthritis and Rheumatology)
Source: Arthritis and Rheumatology - February 11, 2024 Category: Rheumatology Authors: Megan Kay Wood, Abdel Daoud, Monica Vladut Talor, Hannah Maryam Kalinoski, David Matthew Hughes, Camille Marie Jaime, Jody Elizabeth Hooper, Taejoon Won, Daniela Čiháková Tags: Full Length Source Type: research

Clinical Images: A Strange Reaction After a Hyaluronic Acid Injection
(Source: Arthritis and Rheumatology)
Source: Arthritis and Rheumatology - February 11, 2024 Category: Rheumatology Authors: Marie Piroth, Youta Fanjat, Nathalie Cardot ‐Leccia, Christian Roux, Thierry Passeron Tags: Clinical Image Source Type: research

Fractures in Patients With Acute Calcium Pyrophosphate Crystal Arthritis Versus Matched Comparators in a Large Cohort Study
ConclusionIn this first published study of fractures and CPPD, fracture risk was nearly doubled in patients with acute CPP crystal arthritis. (Source: Arthritis and Rheumatology)
Source: Arthritis and Rheumatology - February 9, 2024 Category: Rheumatology Authors: Sara K. Tedeschi, Keigo Hayashi, Ann Rosenthal, Muneet Gill, Javier Marrugo, Sho Fukui, Ellen Gravallese, Daniel H. Solomon Tags: Brief Report Source Type: research

Using two predictive models captures two types of poor outcomes in knee arthroplasty: A multisite longitudinal cohort study
ConclusionsAppropriateness criteria and LCA estimates provided combined poor outcome estimates that were approximately double the commonly reported poor outcome of 20%. Rates of poor outcome could be reduced if clinicians screened patients using Appropriateness criteria and LCA predictors prior to surgery to optimize outcome. (Source: Arthritis and Rheumatology)
Source: Arthritis and Rheumatology - February 8, 2024 Category: Rheumatology Authors: Daniel L. Riddle, Levent Dumenci Tags: Full Length Source Type: research

Rheum at the Table for Everyone: A Call to Expand Rheumatology Knowledge for Primary Care Providers
(Source: Arthritis and Rheumatology)
Source: Arthritis and Rheumatology - February 7, 2024 Category: Rheumatology Authors: Mary E. Margaretten, Jinoos Yazdany, Jennifer Mandal Tags: Notes from the Field Source Type: research

Histone ‐Specific CD4+ T Cell Plasticity in Active and Quiescent Systemic Lupus Erythematosus
ConclusionHistone-specific T cells are selectively detected in patients with SLE, and their concentration in the blood varies with disease activity, suggesting that they represent innovative tools for patient stratification and therapy. (Source: Arthritis and Rheumatology)
Source: Arthritis and Rheumatology - February 7, 2024 Category: Rheumatology Authors: Giuseppe A. Ramirez, Elena Tassi, Maddalena Noviello, Benedetta A. Mazzi, Luca Moroni, Lorena Citterio, Laura Zagato, Enrico Tombetti, Matteo Doglio, Elena M. Baldissera, Enrica P. Bozzolo, Chiara Bonini, Lorenzo Dagna, Angelo A. Manfredi Tags: Full Length Source Type: research

Correspondence and comments on American College of Rheumatology and EULAR antiphospholipid syndrome classification criteria: comment on the article by Barbhaiya et al
(Source: Arthritis and Rheumatology)
Source: Arthritis and Rheumatology - February 7, 2024 Category: Rheumatology Authors: Jaume Alijotas ‐Reig, Joana Marques‐Soares, Enrique Esteve‐Valverde, Francesc Miró‐Mur, Cristina Belizna, Sebastian Udry, Omar Latino, Raquel Ferrer‐Oliveras, Arsenne Mekinian, Luis Saez‐Comet, Sara de Carolis, Ariella Hoxha, Elef Tags: Letters Source Type: research