A Multilayered Post –Genome‐Wide Association Study Analysis Pipeline Defines Functional Variants and Target Genes for Systemic Lupus Erythematosus
ConclusionWe demonstrate and validate post-GWAS strategies for using multidimensional data to prioritize likely causal variants with cognate gene targets underlying SLE pathogenesis. Our results provide a catalog of significantly SLE-associated SNPs and loci, target genes, and likely biochemical mechanisms to guide experimental characterization. (Source: Arthritis and Rheumatology)
Source: Arthritis and Rheumatology - March 27, 2024 Category: Rheumatology Authors: Mehdi Fazel ‐Najafabadi,
Loren L. Looger,
Harikrishna Reddy Rallabandi,
Swapan K. Nath Tags: Full Length Source Type: research
Clinical Connections
(Source: Arthritis and Rheumatology)
Source: Arthritis and Rheumatology - March 27, 2024 Category: Rheumatology Tags: Clinical Connections Source Type: research
In This Issue
(Source: Arthritis and Rheumatology)
Source: Arthritis and Rheumatology - March 27, 2024 Category: Rheumatology Tags: In This Issue Source Type: research
Journal Club
(Source: Arthritis and Rheumatology)
Source: Arthritis and Rheumatology - March 27, 2024 Category: Rheumatology Tags: Journal Club Source Type: research
Issue Information
(Source: Arthritis and Rheumatology)
Source: Arthritis and Rheumatology - March 27, 2024 Category: Rheumatology Tags: Issue Information Source Type: research
Inhibiting the Inhibitor in Synovial Macrophages and Cancer Immunotherapy –Associated Inflammatory Arthritis
(Source: Arthritis and Rheumatology)
Source: Arthritis and Rheumatology - March 27, 2024 Category: Rheumatology Authors: Nisarg J. Shah,
Nunzio Bottini Tags: Editorial Source Type: research
Reply
(Source: Arthritis and Rheumatology)
Source: Arthritis and Rheumatology - March 27, 2024 Category: Rheumatology Authors: Lars Alfredsson,
Lars Klareskog,
Anna Karin Hedstr öm Tags: Letters Source Type: research
Clinical Connections
(Source: Arthritis and Rheumatology)
Source: Arthritis and Rheumatology - March 27, 2024 Category: Rheumatology Tags: Clinical Connections Source Type: research
In This Issue
(Source: Arthritis and Rheumatology)
Source: Arthritis and Rheumatology - March 27, 2024 Category: Rheumatology Tags: In This Issue Source Type: research
Journal Club
(Source: Arthritis and Rheumatology)
Source: Arthritis and Rheumatology - March 27, 2024 Category: Rheumatology Tags: Journal Club Source Type: research
Issue Information
(Source: Arthritis and Rheumatology)
Source: Arthritis and Rheumatology - March 27, 2024 Category: Rheumatology Tags: Issue Information Source Type: research
Clinical Image: Nasal rim sign: A clinical manifestation of dermatomyositis
(Source: Arthritis and Rheumatology)
Source: Arthritis and Rheumatology - March 26, 2024 Category: Rheumatology Authors: Sweta Subhadarshani,
Madeline Hunt,
Kerith Spicknall Tags: Clinical Image Source Type: research
CCL19 ‐Positive Lymph Node Stromal Cells Govern the Onset of Inflammatory Arthritis via Tropomyosin Receptor Kinase
ConclusionCCL19+ lymph node stromal cells are crucially involved in the development of inflammatory arthritis. Therefore, targeting of CCL19+ lymph node stromal cells via TRK could provide a tool to prevent arthritis. (Source: Arthritis and Rheumatology)
Source: Arthritis and Rheumatology - March 22, 2024 Category: Rheumatology Authors: Fabian Sch älter,
Vugar Azizov,
Michael Frech,
Kerstin Dürholz,
Eva Schmid,
Anna Hendel,
Ilann Sarfati,
Yuichi Maeda,
Maria Sokolova,
Ippei Miyagawa,
Kristin Focke,
Kerstin Sarter,
Lisa G. M. van Baarsen,
Stefan Krautwald,
Georg Schett,
M Tags: Full Length Source Type: research
