Epidemiology of sperm DNA fragmentation in a retrospective cohort of 1191 men
Discussion and conclusionAge is the factor that is most strongly associated with sperm DNA fragmentation index levels. Our analysis of 1191 samples indicates that between the ages of 19 and 59, the sperm DNA fragmentation index increases by an average of 2% each year. Intriguingly, from an epidemiological perspective, the warm season (spring/summer) is associated with a higher sperm DNA fragmentation index in the study population, possibly due to the deleterious effect of temperature on sperm quality. Some neurological diseases, such as epilepsy, are associated with decreased sperm DNA integrity. This observation could be ...
Source: Andrology - June 17, 2023 Category: Urology & Nephrology Authors: Parisa Yazdanpanah Ghadikolaei,
Leila Rashki Ghaleno,
Samira Vesali,
Ehsan Janzamin,
Mohammad Ali Sadighi Gilani,
Hesamoddin Sajadi,
Ahmad Vosough Taghi Dizaj,
Abdolhossein Shahverdi,
Jo ël R. Drevet,
AliReza Alizadeh Moghadam Masouleh Tags: ORIGINAL ARTICLE Source Type: research
Is telomere length a biomarker of sperm quality? A systematic review and meta ‐analysis of observational studies
ConclusionThe current systematic review and meta-analysis suggest the potential role of sperm or leukocyte telomere length as a reliable biomarker of semen quality, which may help distinguish between infertility conditions beyond the routine semen analysis.This article is protected by copyright. All rights reserved (Source: Andrology)
Source: Andrology - June 17, 2023 Category: Urology & Nephrology Authors: Mar ía Fernández de la Puente,
Albert Salas‐Huetos,
Cristina Valle‐Hita,
Nancy Babio,
Michelle M. Murphy,
Silvia Canudas,
Jordi Salas‐Salvadó Tags: ORIGINAL ARTICLE Source Type: research
Comparison of the gut microbiome composition between men with erectile dysfunction and a matched cohort: A pilot study
ConclusionsThe results of this study do not support a significant association between the gut microbiome and erectile dysfunction. Further research is needed to fully understand the relationship between these two conditions.This article is protected by copyright. All rights reserved (Source: Andrology)
Source: Andrology - June 15, 2023 Category: Urology & Nephrology Authors: Mohamad M. Osman,
Muhammed A. Hammad,
David W. Barham,
Ryan Toma,
Farouk M. El ‐Khatib,
Sharmin Dianatnejad,
Jeanie Nguyen,
Maxwell Towe,
Edward Choi,
Qiaqia Wu,
Guruduth Banavar,
Ying Cai,
Pedro Moura,
Nan Shen,
Momchilo Vuyisich,
Natali Tags: ORIGINAL ARTICLE Source Type: research
Cell ‐type‐specific determination of reactive oxygen species by flow cytometry
ConclusionReactive oxygen species-overproducing leukocytospermic and normozoospermic seminal samples can reliably be differentiated based on reactive oxygen species mean fluorescence intensity measurement. (Source: Andrology)
Source: Andrology - June 14, 2023 Category: Urology & Nephrology Authors: Agnes Hajnal,
Noemi Bogdandi,
Judit Marokh ázi,
Dorina Guba,
Endre G. Mikus Tags: ORIGINAL ARTICLE Source Type: research
Issue Information
(Source: Andrology)
Source: Andrology - June 13, 2023 Category: Urology & Nephrology Tags: ISSUE INFORMATION Source Type: research
New horizons in testis biology and men's health: a special issue of the XXVIth North American testis workshop
(Source: Andrology)
Source: Andrology - June 13, 2023 Category: Urology & Nephrology Authors: Wei Yan,
Kate L. Loveland Tags: EDITORIAL Source Type: research
Effect of oestrogen modulation on semen parameters in men with secondary hypogonadism; systematic review and meta ‐analysis
This article is protected by copyright. All rights reserved (Source: Andrology)
Source: Andrology - June 12, 2023 Category: Urology & Nephrology Authors: Nipun Lakshitha Silva,
Harsha Dissanayake,
Camila Suarez,
R E Wickramarachchi,
Ranjith Ramasamy,
Waljit S. Dhillo,
Suks Minhas,
Giovanni Corona,
Channa N Jayasena Tags: ORIGINAL ARTICLE Source Type: research
Novel biallelic variants in DNAH1 cause multiple morphological abnormalities of sperm flagella with favorable outcomes of fertility after ICSI in Han Chinese males
Conclusion: These findings further expand the variant spectrum ofDNAH1 gene related to MMAF and male infertility in humans, thus providing new information for the molecular diagnosis of asthenoteratozoospermia. The favorable fertility outcomes of ICSI will facilitate the genetic counseling and clinical treatment of infertile males with MMAF in the future.This article is protected by copyright. All rights reserved (Source: Andrology)
Source: Andrology - June 11, 2023 Category: Urology & Nephrology Authors: Shunhua Long,
Longlong Fu,
Jing Ma,
Haibing Yu,
Xiangrong Tang,
Tingwenyi Hu,
Wei Han,
Weiwei Liu,
Haiyuan Liao,
Tao Fu,
Guoning Huang,
Wenhong Lu,
Tingting Lin Tags: ORIGINAL ARTICLE Source Type: research
Functional genomics of the human epididymis: Further characterization of efferent ducts and model systems by single cell RNA ‐seq analysis
ConclusionSingle cell RNA-seq data from the human epididymis make a valuable contribution to our understanding of this highly specialized organ.This article is protected by copyright. All rights reserved (Source: Andrology)
Source: Andrology - June 10, 2023 Category: Urology & Nephrology Authors: Shih ‐Hsing Leir,
Alekh Paranjapye,
Ann Harris Tags: ORIGINAL ARTICLE Source Type: research
Lactate as the sole energy substrate induces spontaneous acrosome reaction in viable stallion sperm
ConclusionThese findings highlight the delicate control of key sperm functions and may serve as a basis to increase our understanding of stallion sperm physiology.This article is protected by copyright. All rights reserved (Source: Andrology)
Source: Andrology - June 10, 2023 Category: Urology & Nephrology Authors: Luisa Ram írez‐Agámez,
Camilo Hernández‐Avilés,
Isabel Ortíz,
Charles C. Love,
Dickson D. Varner,
Katrin Hinrichs Tags: ORIGINAL ARTICLE Source Type: research
Validation of the relationship between rapid eye movement sleep and sleep ‐related erections in healthy adults by a feasible instrument fitbit charge 2TM
This article is protected by copyright. All rights reserved (Source: Andrology)
Source: Andrology - June 10, 2023 Category: Urology & Nephrology Authors: Guodong Liu,
Yuyang Zhang,
Wei Zhang,
Xu Wu,
Hui Jiang,
Xiansheng Zhang Tags: ORIGINAL ARTICLE Source Type: research
BMP2 restores erectile dysfunction through neurovascular regeneration and fibrosis reduction in diabetic mice
ConclusionBMP2 modulates neurovascular regeneration and inhibits fibrosis to revive the mice's erection function in diabetic conditions. Our findings propose that the BMP2 protein represents a novel and promising approach to treating diabetes-related erectile dysfunction (ED).This article is protected by copyright. All rights reserved (Source: Andrology)
Source: Andrology - June 9, 2023 Category: Urology & Nephrology Authors: Mi ‐hye Kwon,
Beom Yong Rho,
Min‐Ji Choi,
Anita Limanjaya,
Jiyeon Ock,
Guo Nan Yin,
Suk‐Won Jin,
Jun‐Kyu Suh,
Doo Yong Chung,
Ji‐Kan Ryu Tags: ORIGINAL ARTICLE Source Type: research
A novel SNP in HUWE1 promoter confers increased risk of NOA by affecting the RA/RAR α pathway in Chinese individuals
ConclusionsAnHUWE1 promoter SNP significantly downregulates its expression in NOA patients. Mechanistically, HUWE1 regulates germ cell differentiation during meiotic prophase through its participation in RA/RAR α signaling and subsequent modulation of γH2AX. Taken together, these results strongly suggest that the genetic polymorphisms ofHUWE1 are closely related to spermatogenesis and NOA pathogenesis.This article is protected by copyright. All rights reserved (Source: Andrology)
Source: Andrology - June 8, 2023 Category: Urology & Nephrology Authors: Xudong Shan,
Xueguang Zhang,
Gelin Huang,
Jiao Lv,
Zixia Ye,
Chuan Jiang,
Xiaohui Jiang,
Jianxing Cheng,
Haocheng Lin,
Hui Jiang,
Huanxun Yue,
Zhengrong Wang,
Wenming Xu Tags: ORIGINAL ARTICLE Source Type: research
A 2 ‐week high‐intensity interval training intervention improves ejaculation control among men with premature ejaculation
Discussion and conclusionIn summary, HIIT intervention may reduce PE symptoms in men with PE. The heart-rate increase during the intervention may be a key factor influencing the effect of the HIIT intervention on PE symptoms. (Source: Andrology)
Source: Andrology - June 8, 2023 Category: Urology & Nephrology Authors: Caoyuan Niu,
Guangju Wen,
Daniel Ventus,
Yikang Zhang,
Patrick Jern,
Pekka Santtila Tags: ORIGINAL ARTICLE Source Type: research
Intracytoplasmic sperm injection vs. in ‐vitro fertilization in couples in whom the male partners had a semen analysis within normal reference ranges: An open debate
AbstractDuring recent decades, the application of intracytoplasmic sperm injection has increased considerably worldwide, especially in couples with non-male factor infertility. However, several studies analyzing the broad use of intracytoplasmic sperm injection, even in cases with a normal semen analysis, have collectively demonstrated no benefits compared to conventional in-vitro fertilization. Currently, there is insufficient evidence to support the intracytoplasmic sperm injection technique vs. in-vitro fertilization in cases of poor ovarian response or a low number of oocytes collected, or in patients with advanced mat...
Source: Andrology - June 8, 2023 Category: Urology & Nephrology Authors: Romualdo Sciorio,
Steven D. Fleming Tags: OPINION Source Type: research
