Sperm DNA damage: the possible link between obesity and male infertility, an update of the current literature
This article is protected by copyright. All rights reserved (Source: Andrology)
Source: Andrology - February 15, 2023 Category: Urology & Nephrology Authors: Andrew Peel,
Anmol Saini,
Joshua C. Deluao,
Nicole O. McPherson Tags: REVIEW ARTICLE Source Type: research
Issue Information
(Source: Andrology)
Source: Andrology - February 15, 2023 Category: Urology & Nephrology Tags: ISSUE INFORMATION Source Type: research
Erectile dysfunction, anxiety, perceived stress, and insomnia are more common among acquired premature ejaculation patients in contrast to other premature ejaculation syndromes
(Source: Andrology)
Source: Andrology - February 15, 2023 Category: Urology & Nephrology Authors: Elena Colonnello,
Andrea Sansone,
Emmanuele A. Jannini Tags: LETTER TO THE EDITOR Source Type: research
The MAEL expression in mitochondria of human spermatozoa and the association with asthenozoospermia
Conclusions: We highlight prominent MAEL expression in the intra-testicular spermatid and the mitochondria of ejaculated spermatozoa. MAEL directly binds toGPX4 andUBL4B, and loss of MAEL induces mitochondrial dysfunction. MAEL-mitochondrial function-motility relationship might advance our understanding of the causes of asthenozoospermia.This article is protected by copyright. All rights reserved (Source: Andrology)
Source: Andrology - February 14, 2023 Category: Urology & Nephrology Authors: Yu ‐Sheng Cheng,
Hsing‐Yi Chen,
Yu‐Chiao Lin,
Yi‐Syuan Lin,
Yi‐Chun Yeh,
Yi‐Hsuan Yeh,
Yung‐Hsuan Cheng,
Yung‐Ming Lin,
Han‐Yu Weng,
Tsung‐Yen Lin,
Shih‐Chieh Lin Tags: ORIGINAL ARTICLE Source Type: research
Congenital male genital malformations and paternal health: An analysis of the US claims data
ConclusionsFathers with multiple components of metabolic syndrome in the preconception period were observed to be at increased risk for having sons born with hypospadias. The results support the association between a man's andrological and overall health. (Source: Andrology)
Source: Andrology - February 13, 2023 Category: Urology & Nephrology Authors: Bo Yu,
Chiyuan Amy Zhang,
Tony Chen,
Evan Mulloy,
Gary M. Shaw,
Michael L. Eisenberg Tags: ORIGINAL ARTICLE Source Type: research
Extra ‐virgin olive oil ameliorates high‐fat diet‐induced seminal and testicular disorders by modulating the cholesterol pathway
Discussion and conclusionsThe combination of high-fat diet with extra-virgin olive oil encourages testicular recovery by modifying the expression of the enzymes related to intracellular cholesterol management. (Source: Andrology)
Source: Andrology - February 12, 2023 Category: Urology & Nephrology Authors: Abi Karenina Funes,
Mar ía Virginia Avena,
Jorge Ibañez,
Layla Simón,
Leonor Ituarte,
Regina Colombo,
Adrián Roldán,
María Inés Conte,
María Ángeles Monclus,
Paola Boarelli,
Miguel Walter Fornés,
Tania Estefanía Saez Lancellotti Tags: ORIGINAL ARTICLE Source Type: research
Low ‐intensity pulsed ultrasound ameliorates erectile dysfunction induced by bilateral cavernous nerve injury through enhancing schwann cell‐mediated cavernous nerve regeneration
Conclusions: LIPUS promoted nerve regeneration and ameliorated erectile function by enhancing SCs proliferation, migration and neurotrophic factor NGF expression. The TrkB/Akt/CREB axis is the possible mechanism of LIPUS-mediated SC activation. LIPUS-based therapy could be a novel potential treatment strategy for cavernous nerve injury-induced neurogenic ED.This article is protected by copyright. All rights reserved (Source: Andrology)
Source: Andrology - February 11, 2023 Category: Urology & Nephrology Authors: Zitaiyu Li,
Kun Ye,
Yinghao Yin,
Jun Zhou,
Dongjie Li,
Yu Gan,
Dongyi Peng,
Liangyu Zhao,
Ming Xiao,
Yihong Zhou,
Yingbo Dai,
Yuxin Tang Tags: ORIGINAL ARTICLE Source Type: research
From waterloo to the great wall: A retrospective, multicenter study on the clinical practice and cultural attitudes in the management of premature ejaculation, in china
In conclusion, taking switching rates as surrogate markers of treatment failure, this real-life study – the largest in the field - shows that in a more patient-oriented (as in Chinese medical culture), and less symptom-oriented (as in Western medical attitudes), Dapoxetine is a successful treatment for PE patients, with higher reliability when used alone or as part of combined and integrated thera pies.This article is protected by copyright. All rights reserved (Source: Andrology)
Source: Andrology - February 8, 2023 Category: Urology & Nephrology Authors: Andrea Sansone,
Jianlin Yuan,
Guangdong Hou,
Lei Zhang,
Ming Gao,
Zhe Zhang,
Jiang Hui,
Fu Wang,
Jun Guo,
Qiang Geng,
Ming Wang,
Xiansheng Zhang,
Xi Yu,
Zhang Yan,
Jin ‐Chuan Liu,
Yong‐Gang Duan,
Dinesh Nagrale,
Zhiguo Chen,
Emmanuel Tags: ORIGINAL ARTICLE Source Type: research
Vital function of DRD4 in Dapoxetine medicated premature ejaculation treatment
ConclusionIt is a novel mechanism that dapoxetine take effect of PE treatment through up-regulating the dopamine's receptors DRD4, which indicated that upregulated DRD4 would enhance the dapoxetine effect in PE treatment. This may lead to the development of novel therapeutic interventions for PE.This article is protected by copyright. All rights reserved (Source: Andrology)
Source: Andrology - February 7, 2023 Category: Urology & Nephrology Authors: Pan Gao,
Xi Liu,
Tianle Zhu,
Rui Gao,
Jingjing Gao,
Yao Zhang,
Hui Jiang,
Houbao Huang,
Xiansheng Zhang Tags: ORIGINAL ARTICLE Source Type: research
TENT5D disruption causes oligoasthenoteratozoospermia and male infertility
ConclusionMutation inTENT5D results in OAT and male infertility, and this terrible situation could be rescued by ICSI.This article is protected by copyright. All rights reserved (Source: Andrology)
Source: Andrology - February 7, 2023 Category: Urology & Nephrology Authors: Yanwei Sha,
Wensheng Liu,
Songxi Tang,
Xiaoya Zhang,
Ziyi Xiao,
Yuwei Xiao,
Hongjing Deng,
Huiliang Zhou,
Xiaoli Wei Tags: ORIGINAL ARTICLE Source Type: research
What are Sertoli cells? Historical, methodological, and functional aspects
Sertoli cells are somatic cells that are in close contact with germ cells in the mammalian testes. They have multiple functions and fulfill key roles for the development and proper maturation of spermatogenic cells into functional spermatozoa. One of their most important properties is to release trophic factors and supply nutrients to germ cells. But they are also involved in the regulation of the immune system in testis, and provide an immunologically privileged environment for developing germ cells. Because they are so essential for reproductive cells, their alterations can have detrimental consequences for fertility. Ma...
Source: Andrology - February 6, 2023 Category: Urology & Nephrology Authors: Kristina M. Thumfart,
Isabelle M. Mansuy Tags: REVIEW ARTICLE Source Type: research
Diffusion ‐weighted magnetic resonance imaging and magnetic resonance spectroscopy for non‐invasive characterization of azoospermia: A prospective comparative single‐center study
ConclusionsNormalized apparent diffusion coefficient and proton magnetic resonance spectroscopy are helpful in differentiating obstructive azoospermia from non-obstructive azoospermia and predicting sperm retrieval and related histological alterations in men with non-obstructive azoospermia. (Source: Andrology)
Source: Andrology - February 6, 2023 Category: Urology & Nephrology Authors: Ahmed Hesham Said,
Ahmed Ragab,
Wael Zohdy,
Ahmed Sayed Ibrahim,
Ahmed Sayed Abd El Basset Tags: ORIGINAL ARTICLE Source Type: research
Sperm DNA fragmentation and idiopathic recurrent pregnancy loss: Results from a multicenter case –control study
ConclusionsMen within couples affected by recurrent pregnancy loss or infertility had a significantly higher rate of sperm DNA fragmentation compared to fertile controls. However, after adjusting for covariates, sperm DNA fragmentation index was associated only with recurrent pregnancy loss. (Source: Andrology)
Source: Andrology - February 4, 2023 Category: Urology & Nephrology Authors: Andrea Busnelli,
Andrea Garolla,
Elena Di Credico,
Silvia D'Ippolito,
Anna Maria Merola,
Domenico Milardi,
Alfredo Pontecorvi,
Giovanni Scambia,
Nicoletta Di Simone Tags: ORIGINAL ARTICLE Source Type: research
Comparing the adult and pre ‐pubertal testis: Metabolic transitions and the change in the spermatogonial stem cell metabolic microenvironment
AbstractBackgroundSurvivors of childhood cancer often suffer from infertility. While sperm cryopreservation is not feasible before puberty, the patient's own spermatogonial stem cells could serve as a germ cell reservoir, enabling these patients to father their own children in adulthood through the isolation, in vitro expansion, and subsequent transplantation of spermatogonial stem cells. However, this approach requires large numbers of stem cells, and methods for successfully propagating spermatogonial stem cells in the laboratory are yet to be established for higher mammals and humans. The improvement of spermatogonial s...
Source: Andrology - February 3, 2023 Category: Urology & Nephrology Authors: Anna Laura Voigt,
Nathalia Lima e Martins Lara,
Ina Dobrinski Tags: REVIEW ARTICLE Source Type: research
Surgically retrieved sperm for ICSI cycles in non ‐azoospermic males with high sperm DNA fragmentation in semen
Conclusion: Increasing paternal preconception comorbidity is associated with a higher risk that a child requires emergency department and inpatient care in the first years of life. An opportunity exists to engage men in preconception counseling to optimize theirs and their offspring's health. (Source: Andrology)
Source: Andrology - February 3, 2023 Category: Urology & Nephrology Authors: Sandro C. Esteves,
Igor Coimbra,
Jorge Hallak Tags: ORIGINAL ARTICLE Source Type: research
