Novel biallelic variants in DNAH1 cause multiple morphological abnormalities of sperm flagella with favorable outcomes of fertility after ICSI in Han Chinese males
Conclusion: These findings further expand the variant spectrum ofDNAH1 gene related to MMAF and male infertility in humans, thus providing new information for the molecular diagnosis of asthenoteratozoospermia. The favorable fertility outcomes of ICSI will facilitate the genetic counseling and clinical treatment of infertile males with MMAF in the future.This article is protected by copyright. All rights reserved
Source: Andrology - Category: Urology & Nephrology Authors: Shunhua Long,
Longlong Fu,
Jing Ma,
Haibing Yu,
Xiangrong Tang,
Tingwenyi Hu,
Wei Han,
Weiwei Liu,
Haiyuan Liao,
Tao Fu,
Guoning Huang,
Wenhong Lu,
Tingting Lin Tags: ORIGINAL ARTICLE Source Type: research