Predictors of successful salvage microdissection testicular sperm extraction (mTESE) after failed initial TESE in patients with non ‐obstructive azoospermia: a systematic review and meta‐analysis
Conclusion: We found that age, TV, FSH, LH, HS, SCOS and MA were valuable predictors of salvage mTESE, which will assist andrologists in clinical decision making and minimize unnecessary injury to patients.This article is protected by copyright. All rights reserved (Source: Andrology)
Source: Andrology - May 12, 2023 Category: Urology & Nephrology Authors: Feng Zhang,
Mengyang Dai,
Xinyuan Yang,
Yumeng Cheng,
Lijun Ye,
Wensi Huang,
Xi Chen,
Tailang Yin,
Yanwei Sha Tags: REVIEW ARTICLE Source Type: research
The genetic spectrum of a Chinese series of patients with 46, XY disorders of sex development
Conclusion: We identified 21 novel RVs of nine genes, which extended the genetic spectrum of 46, XY DSD pathogenic variants. Our study showed that 60% of the patients were caused byAR, SRD5A2 orNR5A1 P/LP variants. Therefore, PCR amplification and Sanger sequencing of these three genes could be performed firstly to identify the pathogeny of the patients. For those patients whose pathogenic variants had not been found, whole-exome sequencing could be helpful in determining the etiology.This article is protected by copyright. All rights reserved (Source: Andrology)
Source: Andrology - May 6, 2023 Category: Urology & Nephrology Authors: Wei Zhang,
Jiangfeng Mao,
Xi Wang,
Zhiyuan Zhao,
Xiaoxia Zhang,
Bang Sun,
Yaqing Cao,
Min Nie,
Xueyan Wu Tags: ORIGINAL ARTICLE Source Type: research
Knowledge on the male reproductive tract and testicular cancer among adolescents in Austria
Conclusions: This survey demonstrates relevant knowledge deficits of young adults regarding the male reproductive tract, testicular cancer and self-examination.This article is protected by copyright. All rights reserved (Source: Andrology)
Source: Andrology - May 6, 2023 Category: Urology & Nephrology Authors: Ingrid Schauer,
Andreas Banner,
Stephan Madersbacher,
Oliver Anegg Tags: ORIGINAL ARTICLE Source Type: research
Three ‐dimensional analysis of junctions between efferent and epididymal ducts in the human caput epididymis
ConclusionsBy utilizing deep learning, we reconstructed human efferent and caput epididymal ducts and revealed their precise three-dimensional structures, which differed from those of rodents in several aspects. The present results may be useful for analyzing anatomical abnormalities related to some types of male infertility.This article is protected by copyright. All rights reserved (Source: Andrology)
Source: Andrology - May 3, 2023 Category: Urology & Nephrology Authors: Hiroki Nakata,
Shoichi Iseki,
Atsushi Mizokami Tags: ORIGINAL ARTICLE Source Type: research
Spermatozoa cooled to 5 °C one day after collection from porcine commercial semen doses retain sperm functionality with reduced bacterial load
Discussion and conclusionPorcine spermatozoa cooled to 5 °C one day after collection retain functional attributes similar to spermatozoa stored at 17°C, but have a reduced bacterial load. Cooling extended boar semen to 5°C is feasible after transport to avoid modifying semen production. (Source: Andrology)
Source: Andrology - April 25, 2023 Category: Urology & Nephrology Authors: Raul A. Gonzalez ‐Castro,
Fernando J. Peña,
Lisa A. Herickhoff Tags: ORIGINAL ARTICLE Source Type: research
Orexin receptors in paraventricular nucleus influence sexual behavior via regulating the sympathetic outflow in males
ConclusionsOX1R in PVN could influence the ejaculatory reflex via mediating the SNS activity, which might be of great importance in the treatment of premature ejaculation in the future.This article is protected by copyright. All rights reserved (Source: Andrology)
Source: Andrology - April 22, 2023 Category: Urology & Nephrology Authors: Jiao ‐Chen Luan,
Qi‐Jie Zhang,
Xuan Zhou,
Xiang Zhou,
Qi Gu,
Jia‐Dong Xia,
Ning‐hong Song Tags: ORIGINAL ARTICLE Source Type: research
Effects of obesity ‐related anthropometric indices and body composition on erectile dysfunction mediated by coronary artery disease: A Mendelian randomization study
ConclusionThere is a potential causal relationship between obesity-related anthropometric indicators/body composition and ED. Higher waist circumference, leg fat percentage, and arm fat mass may increase the risk of ED, and CAD partly mediates this overall effect. Understanding the causal relationship between obesity and ED and the mediating role of CAD may provide more information for ED intervention and prevention strategies.This article is protected by copyright. All rights reserved (Source: Andrology)
Source: Andrology - April 21, 2023 Category: Urology & Nephrology Authors: Binghao Bao,
Jianqiang Guo,
Lei Zhang,
Zhengkun Pan,
Haonan Huang,
Zhongjian Qin,
Lu Chen,
Baoxing Liu Tags: ORIGINAL ARTICLE Source Type: research
Altered brain activity in diabetic patients with erectile dysfunction revealed by fractional amplitude of low ‐frequency fluctuation: a resting‐state fMRI study
Conclusion: DM-ED patients showed functional changes in brain regions that were closely correlated with sexual dysfunction, which suggested that altered regional brain activity might be related to the pathophysiology of DM-ED.This article is protected by copyright. All rights reserved (Source: Andrology)
Source: Andrology - April 15, 2023 Category: Urology & Nephrology Authors: Ziliang Xiang,
Yingjun Huang,
Yan Xu,
Xue Liu,
Xinfei Huang,
Tao Liu,
Zhaoxu Yang,
Lin Jiang,
Yun Chen,
Jianhuai Chen Tags: ORIGINAL ARTICLE Source Type: research
Spermatozoa cooled to 5 °C one‐day after collection from porcine commercial semen doses retain sperm functionality with reduced bacterial load
Conclusion: Porcine spermatozoa cooled to 5 °C one-day after collection retain functional attributes similar to spermatozoa stored at 17°C but have a reduced bacterial load. Cooling extended boar semen to 5°C is feasible after transport to avoid modifying semen production.This article is protected by copyright. All rights reserved (Source: Andrology)
Source: Andrology - April 14, 2023 Category: Urology & Nephrology Authors: Raul A. Gonzalez ‐Castro,
Fernando J. Peña,
Lisa A. Herickhoff Tags: ORIGINAL ARTICLE Source Type: research
The human sperm proteome —Toward a panel for male fertility testing
ConclusionOur results shed light on the molecular background of the dysfunctionality of the fewer spermatozoa produced in oligozoospermia and syndromes including it. The male infertility network presented may prove useful in further elucidating the molecular mechanism of male infertility. (Source: Andrology)
Source: Andrology - April 13, 2023 Category: Urology & Nephrology Authors: Thomas Greither,
Mario Dejung,
Hermann M. Behre,
Falk Butter,
Holger Herlyn Tags: ORIGINAL ARTICLE Source Type: research
Role of mechanotransduction mediated by YAP/TAZ in the treatment of neurogenic erectile dysfunction with low ‐intensity pulsed ultrasound
This article is protected by copyright. All rights reserved (Source: Andrology)
Source: Andrology - April 12, 2023 Category: Urology & Nephrology Authors: Yang Liu,
Xiao ‐ying Pan,
Xiang‐xiang Zhang,
Ji‐lei Sun,
Yin‐hui Mao,
Yong Yang,
Zhi‐tao Wei Tags: ORIGINAL ARTICLE Source Type: research
Gonadotropin axis and semen quality in young Swiss men after cannabis consumption: Effect of chronicity and modulation by cannabidiol
ConclusionsBecause both CBD and THC are frequently used by men of reproductive age, it is highly relevant to elucidate the potential effects they may have on human reproductive health. This study demonstrates that the mode of cannabis consumption must be considered when evaluating the effect of cannabis on semen quality.This article is protected by copyright. All rights reserved (Source: Andrology)
Source: Andrology - April 12, 2023 Category: Urology & Nephrology Authors: Fanny Zufferey,
Elina Buitrago,
Rita Rahban,
Alfred Senn,
Eric Stettler,
Serge Rudaz,
Serge Nef,
Nicolas Donz é,
Aurélien Thomas,
Michel F. Rossier Tags: ORIGINAL ARTICLE Source Type: research
Novel sperm chromatin dispersion test with artificial intelligence ‐aided halo evaluation: A comparison study with existing modalities
ConclusionsThe novel sperm chromatin dispersion kit and artificial intelligence-aided platform demonstrated significant correlation and agreement with existing sperm chromatin dispersion methods by assessing greater number of spermatozoa. This technique has the potential to provide a rapid and accurate assessment of sperm DNA fragmentation without technical expertise or flow cytometry. (Source: Andrology)
Source: Andrology - April 12, 2023 Category: Urology & Nephrology Authors: Shinnosuke Kuroda,
Keshab Kumar Karna,
Raneen Sawaid Kaiyal,
Rossella Cannarella,
Scott D. Lundy,
Sarah C. Vij,
Ashok Agarwal Tags: ORIGINAL ARTICLE Source Type: research
Lycopene intake and the risk of erectile dysfunction in US adults: NHANES 2001 –2004
ConclusionOur national data suggest that lower dietary lycopene intake is positively associated with an increased risk of ED in US men.This article is protected by copyright. All rights reserved (Source: Andrology)
Source: Andrology - April 11, 2023 Category: Urology & Nephrology Authors: Yue Gao,
Chunhui Liu,
Xun Lu,
Kai Lu,
Lei Zhang,
Weipu Mao,
Kehao Pan,
Zichun Liang,
Chao Sun,
Ming Chen Tags: ORIGINAL ARTICLE Source Type: research
Ciliary neurotrophic factor stimulates stem/progenitor Leydig cell proliferation but inhibits differentiation into its lineage in rats
ConclusionCNTF stimulates the proliferation but blocks the differentiation of stem/progenitor Leydig cells.This article is protected by copyright. All rights reserved (Source: Andrology)
Source: Andrology - April 8, 2023 Category: Urology & Nephrology Authors: Hehua Quan,
Yiyan Wang,
Huitao Li,
Qiqi Zhu,
Xiaofang Chen,
Ren ‐Shan Ge,
Xiaoheng Li Tags: ORIGINAL ARTICLE Source Type: research
