Impact of COVID ‐19 on sperm quality and the prostaglandin and polyamine systems in the seminal fluid
This study compared semen collected from men without positive coronavirus disease 2019 diagnosis with samples obtained from individuals 1 –6 months and 7–30 months post SARS-CoV-2 infection. Semen parameters, thiobarbituric acid reactive substances, cyclooxygenase 2 expression by fluorescence immunocytochemistry and immunoblotting, prostaglandin levels by enzyme immunoassay, ornithine decarboxylase activity by a radioactive assay, and polyamine and acetylated polyamine levels by thin-layer chromatography were assessed.ResultsIn both groups of semen samples from coronavirus disease 2019 recovered men, sperm vitality, to...
Source: Andrology - October 25, 2023 Category: Urology & Nephrology Authors: Mar ía Eugenia Matzkin,
Celina Beguerie,
Ignacio De Zuñiga,
Gustavo Martinez,
Mónica Beatriz Frungieri Tags: ORIGINAL ARTICLE Source Type: research
Issue Information
(Source: Andrology)
Source: Andrology - October 19, 2023 Category: Urology & Nephrology Tags: ISSUE INFORMATION Source Type: research
The following article for this Special Issue was published in a different issue. They can be found in their respective issue
Increased sperm deoxyribonucleic acid damage leads to poor embryo quality and subfertility of male rats treated with methylphenidate hydrochloride in adolescence.ANDR. 2022; 10(8): 1632 –1643.https://doi.org/10.1111/andr.13277 (Source: Andrology)
Source: Andrology - October 19, 2023 Category: Urology & Nephrology Tags: ORIGINAL ARTICLE Source Type: research
Sperm DNA integrity: a special issue exploring the causes, consequences, and treatment of DNA damage in human spermatozoa
(Source: Andrology)
Source: Andrology - October 19, 2023 Category: Urology & Nephrology Authors: Robert John Aitken Tags: EDITORIAL Source Type: research
Microbiome reveals inflammatory ‐related bacteria and putative functional pathways involved in human papillomavirus‐associated penile squamous cell carcinoma
ConclusionWe describe the first microbiome of penile carcinoma, which revealed an abundant and diverse microbiota as well as inflammatory-related taxa (the phyla Proteobacteria and Firmicutes, the generaFusobacterium andPrevotella, and the speciesFinegoldia magma andPseudomonas geniculata) and molecular pathways (chitin derivates degradation, the protocatechuic acid pathway, inositol metabolism, and the sucrose pathway), which have also been linked to inflammation and carcinogenesis. Moreover, we found specific and abundant ASVs in both tumor and non-tumor tissues. Our data encourage further study to better understand the ...
Source: Andrology - October 16, 2023 Category: Urology & Nephrology Authors: Amanda de Deus,
Gabriele Gon çalves,
Jenilson da Silva,
Luís Cláudio de Jesus,
Ana Paula S. Azevedo‐Santos,
Hivana Dall Agnol,
Silma Regina Pereira Tags: ORIGINAL ARTICLE Source Type: research
Inflammatory markers and androstenedione modify the effect of serum testosterone on obesity among men: Findings from a Chinese population
ConclusionInflammatory markers and androstenedione were first found to have modifying effects on the association of testosterone with obesity. Higher levels of testosterone and androstenedione could reduce the inflammation level and risk of obesity, indicating their potential roles in the prevention and treatment of chronic diseases. (Source: Andrology)
Source: Andrology - October 13, 2023 Category: Urology & Nephrology Authors: Changsheng Huan,
Mian Wang,
Yu Song,
Zexin Jia,
Dandan Wei,
Lulu Wang,
Qingqing Xu,
Juan Wang,
Mengzhen Zhao,
Jintian Geng,
Jiayu Shi,
Cuicui Ma,
Zhenxing Mao,
Chongjian Wang,
Wenqian Huo Tags: ORIGINAL ARTICLE Source Type: research
A metabolomic perspective on the mechanisms by which environmental pollutants and lifestyle lead to male infertility
AbstractThe incidence of male infertility (MI) is rising annually. According to epidemiological studies, environmental pollution (e.g., organic, inorganic, and air pollutants), occupational exposure (e.g., high temperature, organic solvents, and pesticides), and poor lifestyle (e.g., diet, sleep, smoking, alcohol consumption, and exercise) are important non-genetic causative factors of MI. Due to multiple and complex causative factors, the dose –effect relationship, and the uncertainty of pathogenicity, the pathogenesis of MI is far from fully clarified. Recent data show that the pathogenesis of MI can be monitored by th...
Source: Andrology - October 11, 2023 Category: Urology & Nephrology Authors: Wen Yang,
Rong Hua,
Yunxia Cao,
Xiaojin He Tags: REVIEW ARTICLE Source Type: research
Vasovasostomy: A systematic review and meta ‐analysis comparing macroscopic, microsurgical, and robot‐assisted microsurgical techniques
ConclusionPatency outcomes for vasovasostomy were best with robot-assisted microsurgical technique, followed by pure microsurgical technique, and conventional macroscopic technique. Further investigations of robot-assisted microsurgical vasovasostomy outcomes and randomized control trials are required to support this evidence. (Source: Andrology)
Source: Andrology - October 8, 2023 Category: Urology & Nephrology Authors: Ishith Seth,
Damien Gibson,
Gabriella Bulloch,
Konrad Joseph,
Jevan Cevik,
Kirby R. Qin,
Shekib Shahbaz,
Warren M. Rozen Tags: ORIGINAL ARTICLE Source Type: research
Differential sperm histone retention in normozoospermic ejaculates of infertile men negatively affects sperm functional competence and embryo quality
Discussion and conclusionHistone retention in spermatozoa can be one of the factors behind the development of idiopathic male infertility. Such spermatozoa may influence embryonic behaviour and thereby affect the success rate of assisted reproductive technology procedures. These results, although descriptive in nature, warrant further research to address the underlying mechanisms behind these clinically important observations. (Source: Andrology)
Source: Andrology - October 7, 2023 Category: Urology & Nephrology Authors: Riddhi Kirit Pandya,
Ameya Jijo,
Aswathi Cheredath,
Shubhashree Uppangala,
Sujith Raj Salian,
Vani R Lakshmi,
Pratap Kumar,
Guruprasad Kalthur,
Sanjay Gupta,
Satish Kumar Adiga Tags: ORIGINAL ARTICLE Source Type: research
The relationship between sperm nuclear DNA fragmentation, mitochondrial DNA fragmentation, and copy number in normal and abnormal human ejaculates
ConclusionHigh-quality ejaculates show lower nuclear SDF and retain less mtDNA copies, with approximately half of them fragmented, so that the absolute number of non-fragmented mtDNA molecules per spermatozoon is extremely low. (Source: Andrology)
Source: Andrology - October 3, 2023 Category: Urology & Nephrology Authors: Ana T ímermans,
Fátima Otero,
Manuel Garrido,
Jaime Gosálvez,
Stephen Johnston,
José Luis Fernández Tags: ORIGINAL ARTICLE Source Type: research
Differential roles of cyclooxygenase enzymes in the regulation of murine juvenile undifferentiated spermatogonia
ConclusionWe report that cyclooxygenase 1 and 2 differentially regulate undifferentiated spermatogonia/spermatogonial stem cell differentiation. Cyclooxygenases regulate Notch3 expression, with the Notch pathway targeted by PGD2. These data suggest an interaction between the eicosanoid and Notch signaling pathways that may be critical for the development of spermatogonial stem cells and subsequent spermatogenesis, cautioning about using cyclooxygenase inhibitors in infants. (Source: Andrology)
Source: Andrology - September 30, 2023 Category: Urology & Nephrology Authors: Amy Tran ‐Guzman,
Amina Khan,
Martine Culty Tags: ORIGINAL ARTICLE Source Type: research
Peyronie's disease response to intralesional collagenase clostridium histolyticum therapy is independent of baseline testosterone
ConclusionNeither total testosterone nor hypogonadism is associated with a degree of improvement after collagenase clostridium histolyticum treatment. (Source: Andrology)
Source: Andrology - September 28, 2023 Category: Urology & Nephrology Authors: Douglas Schneider,
Mitchell O'Leary,
Eliad Amini,
Jake Miller,
Nick Hassas,
Jeanie Nguyen,
Muhammed A. Moukhtar Hammad,
David Barham,
Faysal A. Yafi Tags: ORIGINAL ARTICLE Source Type: research
What do patients with Peyronie's disease expect from therapy? A prospective multi ‐center study
ConclusionPD patients expect both more benefit and more harm from surgery. In addition, patients undergoing surgery have more psychological and physical symptoms and more symptom bother. To set realistic expectations, it is of pivotal importance to assess patients ’ expectations before starting treatment. (Source: Andrology)
Source: Andrology - September 27, 2023 Category: Urology & Nephrology Authors: Lukas Sch äfer,
Jann F. Cremers,
Bahne Witschel,
Victor Schüttfort,
Timo O. Nieder,
Frederik König,
Malte W. Vetterlein,
Philipp Gild,
Roland Dahlem,
Margit Fisch,
Sabine Kliesch,
Armin Soave Tags: ORIGINAL ARTICLE Source Type: research
Prostate cancer therapy outcome prediction: are miRNAs a suitable guide for therapeutic decisions?
ConclusionThe selected miRNA-based panel has the potential to be a guide for therapeutic decision making in the effective treatment of PCa. (Source: Andrology)
Source: Andrology - September 27, 2023 Category: Urology & Nephrology Authors: MariaYu Konoshenko,
Pavel Laktionov,
Olga Bryzgunova Tags: REVIEW ARTICLE Source Type: research
Parental age at birth and biomarkers of fecundity in young Danish men
Discussion and conclusionWe found no strong association between higher parental age and biomarkers of fecundity in young men. However, we cannot exclude poorer semen characteristics in sons born by older mothers or with high age of both parents. (Source: Andrology)
Source: Andrology - September 26, 2023 Category: Urology & Nephrology Authors: Andreas Ernst,
Nis Brix,
Anne Gaml ‐Sørensen,
Linn Håkonsen Arendt,
Gunnar Toft,
Sandra Søgaard Tøttenborg,
Karin Søring Hougaard,
Jens Peter Ellekilde Bonde,
Cecilia Høst Ramlau‐Hansen Tags: ORIGINAL ARTICLE Source Type: research
