Effects of Preconception Exposure to Phthalates on Mouse Sperm Capacitation Parameters
ConclusionOur findings suggest that preconception phthalate exposure affects sperm numbers and phosphorylation of PKA substrates involved in capacitation. Future research is warranted to examine the associations between phthalate exposures and capacitation in human sperm.This article is protected by copyright. All rights reserved (Source: Andrology)
Source: Andrology - March 9, 2023 Category: Urology & Nephrology Authors: Gayatri Mohanty,
Darya A. Tourzani,
Mar ía G. Gervasi,
Emily Houle,
Oladele Oluwayiose,
Alexander Suvorov,
J. Richard Pilsner,
Pablo E. Visconti Tags: ORIGINAL ARTICLE Source Type: research
Causal association of cardiovascular disease with erectile dysfunction: A two ‐sample bidirectional Mendelian randomization analysis
ConclusionsOur results, based on MR, indicated that genetic susceptibility to IS, HF, and CHD was causally associated with ED. These findings can inform prevention and intervention strategies for ED in IS, HF, and CHD patients.This article is protected by copyright. All rights reserved (Source: Andrology)
Source: Andrology - March 9, 2023 Category: Urology & Nephrology Authors: Miaoyong Ye,
Jiaxing Chen,
Jianxiong Ma,
Junwei Wang,
Cunming Zhang,
Baijun Chen,
Zhongbiao Wu,
Fan Zhao,
Lan Ma Tags: ORIGINAL ARTICLE Source Type: research
Kidney function impairment in men with primary infertility: A case ‐control analysis
ConclusionsMild kidney function impairment was found in 9% of asymptomatic and unaware men presenting for primary couple's infertility investigation. This novel finding corroborates growing data on a significant association of male infertility with a poorer overall male health status and the need for tailored preventive strategies.This article is protected by copyright. All rights reserved (Source: Andrology)
Source: Andrology - March 5, 2023 Category: Urology & Nephrology Authors: Giuseppe Fallara,
Paolo Capogrosso,
Edoardo Pozzi,
Federico Belladelli,
Simone Cilio,
Christian Corsini,
Luigi Candela,
Massimiliano Raffo,
Luca Boeri,
Eugenio Ventimiglia,
Marina Pontillo,
Alice Cotellessa,
Alessia d'Arma,
Massimo Alfano,
F Tags: ORIGINAL ARTICLE Source Type: research
Effect of near ‐infrared laser treatment on improving erectile function in rats with diabetes mellitus
ConclusionNIR laser activated mitochondria, improved OS, repaired the damage to penile CC tissue structures caused by DM, and improved erectile function in DM rats. These results thus raise the possibility that human patients with DMED may respond to NIR therapy in a manner that parallels the responses we observed in animal study.This article is protected by copyright. All rights reserved (Source: Andrology)
Source: Andrology - March 4, 2023 Category: Urology & Nephrology Authors: Lin Yang,
Guoxiong Liu,
Dali Jiang,
Guiting Lin,
Zejun Ren,
Hengtong Fan,
Bing Yang,
Liyue Mu,
Tom F. Lue,
Dalin He Tags: ORIGINAL ARTICLE Source Type: research
Development and integration of LensHooke ® R10 for automatic and standardized diagnosis for sperm DNA fragmentation
ConclusionThe R10 SCD assay combined with the X12 semen analysis system is faster, more objective, and provides standardization for sperm DNA fragmentation.This article is protected by copyright. All rights reserved (Source: Andrology)
Source: Andrology - March 4, 2023 Category: Urology & Nephrology Authors: Cheng ‐Teng Hsu,
Chun‐I Lee,
Chun‐Chia Huang,
Tse‐En Wang,
Hui‐Chen Chang,
Li‐Sheng Chang,
Maw‐Sheng Lee Tags: ORIGINAL ARTICLE Source Type: research
Efficacy and safety assessment of traditional Chinese medicine for erectile dysfunction: a meta ‐analysis and trial sequential analysis
ConclusionTCM can gain better responses in improving the IIEF-5 scores, clinical recovery rates, and testosterone levels as an alternative and a complementary treatment, with no increase in side effects. However, more standardized, long-term, TCM and integrative therapy clinical trials are needed to support the clinical application of TCM.This article is protected by copyright. All rights reserved (Source: Andrology)
Source: Andrology - February 28, 2023 Category: Urology & Nephrology Authors: Haoran Wu,
Zezheng Gao,
Dan Dai,
Xing Liu,
Yini Fang,
Xuemei Chen,
Qi Wang Tags: ORIGINAL ARTICLE Source Type: research
Metabolomics profiling of seminal plasma in obesity ‐induced asthenozoospermia
Conclusion: Obesity could affect the metabolite composition in seminal plasma and abnormal energy metabolism in seminal plasma mainly including carbohydrate metabolism and amino acid metabolism was closely related to obesity-induced asthenozoospermia.This article is protected by copyright. All rights reserved (Source: Andrology)
Source: Andrology - February 27, 2023 Category: Urology & Nephrology Authors: Yan ‐fen Zhou,
Yu‐yang Hou,
Qian Ban,
Meng‐ling Zhang,
Tao Huang,
Bo Ma,
Liang Shi,
Qi Zhang Tags: ORIGINAL ARTICLE Source Type: research
Influence of androgens on the innate immune system
AbstractSexual dimorphism is observed in the occurrence, course, and severity of human disease. The difference in immune response between male and female can in part be attributed to sexual genotype. However, immunological differences can also be explained by endocrine-immune interactions. Specifically, androgens possess the ability of directly modulating the development and function of immune cells. While androgens generally contribute to immunosuppressive effects, this is not necessarily always the case. This review aims to present the current state of knowledge on androgens in shaping sex-dependent difference in the inn...
Source: Andrology - February 25, 2023 Category: Urology & Nephrology Authors: Seline Vancolen,
Guillaume S ébire,
Bernard Robaire Tags: ORIGINAL ARTICLE Source Type: research
The impact of semen parameters on ICSI and pregnancy outcomes in egg recipient cycles with PGT ‐A
This article is protected by copyright. All rights reserved (Source: Andrology)
Source: Andrology - February 24, 2023 Category: Urology & Nephrology Authors: AL Grammatis,
A Pappas,
G Kokkali,
K Pantos,
N Vlahos Tags: ORIGINAL ARTICLE Source Type: research
Testicular torsion in vivo models: Mechanisms and treatments
AbstractTesticular torsion (TT) is a condition in which a testis rotates around its longitudinal axis and twists the spermatic cord. This in turn results in a significant decrease in blood flow and perfusion of testicular tissue. During TT, the testicular tissue is affected by ischemia, heat stress, hypoxia, and oxidative and nitrosative stress. The TT should be considered an emergency condition and surgical intervention (testicular detorsion (TD)) as the sole treatment option in viable cases involves counter-rotation on twisted testes associated, when possible, to orchipexy, in order to avoid recurrence. Possible TD side-...
Source: Andrology - February 24, 2023 Category: Urology & Nephrology Authors: Aram Minas,
Sina Mahmoudabadi,
Naeimeh Shamsi Gamchi,
Mariana Pereira Antoniassi,
Arash Alizadeh,
Ricardo Pimenta Bertolla Tags: REVIEW ARTICLE Source Type: research
Real ‐world practice in peyronie's disease management: Results from a national survey of urologists
ConclusionsA significant proportion of urologists reported PD management practices that are not evidence based and not guideline-supported.This article is protected by copyright. All rights reserved (Source: Andrology)
Source: Andrology - February 24, 2023 Category: Urology & Nephrology Authors: Aaron Brant,
Spyridon P. Basourakos,
Patrick Lewicki,
Caroline Kang,
Jessica Marinaro,
Nahid Punjani,
James Kashanian Tags: ORIGINAL ARTICLE Source Type: research
Characterization of acrosin and acrosin binding protein as novel CRISP2 interacting proteins in boar spermatozoa
This article is protected by copyright. All rights reserved (Source: Andrology)
Source: Andrology - February 23, 2023 Category: Urology & Nephrology Authors: Min Zhang,
Riccardo Zenezini Chiozzi,
Elizabeth G Bromfield,
Albert JR Heck,
J Bernd Helms,
Bart M Gadella Tags: ORIGINAL ARTICLE Source Type: research
Surgically retrieved spermatozoa for ICSI cycles in non ‐azoospermic males with high sperm DNA fragmentation in semen
AbstractIntracytoplasmic sperm injection (ICSI) using surgically retrieved spermatozoa outside the classic context of azoospermia has been increasingly used to overcome infertility. The primary indications include high levels of sperm DNA damage in ejaculated spermatozoa and severe oligozoospermia or cryptozoospermia, particularly in couples with ICSI failure for no apparent reason. Current evidence suggests that surgically retrieved spermatozoa for ICSI in the above context improves outcomes, mainly concerning pregnancy and miscarriage rates. The reasons are not fully understood but may be related to the lower leve...
Source: Andrology - February 18, 2023 Category: Urology & Nephrology Authors: Sandro C. Esteves,
Igor Coimbra,
Jorge Hallak Tags: REVIEW ARTICLE Source Type: research
Transcriptional regulation of spatiotemporal gene expression within the seminiferous epithelium: mouse Acrv1 gene as a model
This article is protected by copyright. All rights reserved (Source: Andrology)
Source: Andrology - February 16, 2023 Category: Urology & Nephrology Authors: Prabhakara P. Reddi Tags: REVIEW ARTICLE Source Type: research
The effect of testosterone treatment on bone mineral density in Klinefelter syndrome: A retrospective cohort study
ConclusionTRT results in BMD gain in patients with KS with testosterone deficiency, mainly at the lumbar spine. However, this effect is limited (0.62% per year). Patients who were not treated with TRT because of sufficient endogenous testosterone levels, showed only the predicted age-related bone loss during follow-up. The need for TRT in maintaining bone health in KS should be evaluated on an individual basis according to the degree of sex steroid deficiency.This article is protected by copyright. All rights reserved (Source: Andrology)
Source: Andrology - February 16, 2023 Category: Urology & Nephrology Authors: Stien Willems,
Karel David,
Brigitte Decallonne,
Philippe Marcq,
Leen Antonio,
Dirk Vanderschueren Tags: ORIGINAL ARTICLE Source Type: research
