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The Safety Assessment of Cosmetic Perfumes by Using In Chemico and In Vitro Methods in Combination with GC-MS/MS Analysis
Altern Lab Anim. 2023 Jul;51(4):224-248. doi: 10.1177/02611929231184635. Epub 2023 Jun 28.ABSTRACTAnimal testing has been prohibited for the safety assessment of cosmetic ingredients or finished products. Thus, alternative non-animal methods, followed by confirmatory clinical studies on human volunteers, should be used as the sole legally acceptable approach within the EU. The safety assessment of cosmetic products requires the involvement of multiple scientific disciplines, including analytical chemistry and biomedicine, as well as in chemico, in vitro and in silico toxicology. Recent data suggest that fragrance component...
Source: Alternatives to Laboratory Animals : ATLA - June 28, 2023 Category: Research Authors: Mark éta Dvořáková Lada Svobodov á Marian Rucki V áclav Ševčík Barbora Ho šíková Jan Chrz Hana Bendov á Kristina Kejlov á Danu še Očadlíková Marek Mal ý Hana Kol ářová Marika Mannerstr öm Helena Kan ďárová Dagmar J írová Source Type: research

The Safety Assessment of Cosmetic Perfumes by Using In Chemico and In Vitro Methods in Combination with GC-MS/MS Analysis
Altern Lab Anim. 2023 Jun 28:2611929231184635. doi: 10.1177/02611929231184635. Online ahead of print.ABSTRACTAnimal testing has been prohibited for the safety assessment of cosmetic ingredients or finished products. Thus, alternative non-animal methods, followed by confirmatory clinical studies on human volunteers, should be used as the sole legally acceptable approach within the EU. The safety assessment of cosmetic products requires the involvement of multiple scientific disciplines, including analytical chemistry and biomedicine, as well as in chemico, in vitro and in silico toxicology. Recent data suggest that fragranc...
Source: Alternatives to Laboratory Animals : ATLA - June 28, 2023 Category: Research Authors: Mark éta Dvořáková Lada Svobodov á Marian Rucki V áclav Ševčík Barbora Ho šíková Jan Chrz Hana Bendov á Kristina Kejlov á Danu še Očadlíková Marek Mal ý Hana Kol ářová Marika Mannerstr öm Helena Kan ďárová Dagmar J írová Source Type: research