What is the scientific basis of 10,000 steps a day?
It is often suggested that you should take 10,000 steps a day, seven days a week as part of your fitness program. Actually the number of steps need not assess the amount of walking you do. The distance walked will depend on your stride length. Anyway the concept of 10,000 steps a day is quite popular and many use pedometers to track the daily step count and often post it on social media to encourage others.
Thought of just looking at PubMed on the scientific data on the utility of 10,000 steps a day. Ohta T and colleagues checked the effect on coronary risk factors in obese middle aged subjects and the data was published ...
Source: Cardiophile MD - December 7, 2021 Category: Cardiology Authors: Prof. Dr. Johnson Francis Tags: General Cardiology Source Type: blogs
On China ’s Trade Practices, the United States Is Ramping Up Efforts with Allies
Inu ManakThis week, trade ministers from around the world were supposed to meet in Geneva to discuss a number of pressing trade issues, including new disciplines to rein in government subsidies in thefishing andagricultural sectors, and to develop a path forward to liberalize trade in areas such asenvironmental goods ande ‑commerce. These meetings are now postponed due to the emergence of the Omicron variant. These face to face meetings are not only important for addressing multilateral issues at the World Trade Organization, but also provide an opportunity for countries to discuss other trade challenges. While...
Source: Cato-at-liberty - December 1, 2021 Category: American Health Authors: Inu Manak Source Type: blogs
Doomsday in December?
I’m run down and sick, so I’m posting something positive every day this week until I lift my spirits.There is a reason I’m depressed. It’s more than havingmajor and persistent depression disorder. I’ve had a surprisingly cruddy year. I have to admit that I’m frustrated because my coping strategies are failing me. This is the sort of year that could only happen to a protagonist in a dark comedy. I’ve already written before how I was severely sick for seven monthsbefore the pandemic began. This feels like slow death sometimes. I’m so isolated from others, I’m forgetting h...
Source: The Splintered Mind by Douglas Cootey - December 1, 2021 Category: Psychiatry Tags: Depression Family Goodreads Writing Source Type: blogs
Feeling Down, So It ’s Time To Be Grateful
Sometimes life gets me down. So what am I going to do about it? I ’ve been way too sick to blog lately or post here. I mostly lay in bed and cough. It’s a party! But I did get somebook writing in. One more chapter, and I’ll be ready to post it on Kindle Vella. Now I just need to design a fetching avatar for the book.I started feeling better yesterday …marginally. I had energy enough to remotely log into my four computers and setup SSH key pairs, moved some doge into a dedicated hot wallet, listed items on eBay, updated my dynamic DNS account to make sure my web and ebook servers were working, downgraded Calibr...
Source: The Splintered Mind by Douglas Cootey - November 29, 2021 Category: Psychiatry Tags: Depression Goodreads Spinning Visualizing Source Type: blogs
EINSTEIN-Jr clinical trials of Rivaroxaban in children
Rivaroxaban is useful for treatment of venous thromboembolism in adults and is associated with lower risk of bleeding compared to standard anticoagulants. EINSTEIN-Jr phase 2 used bodyweight adjusted rivaroxaban for children with venous thromboembolism [1]. It was a single arm multicenter study three age groups – children younger than 6 months, those in age group 6 months to 5 years and in children and adolescents between 6-17 years. Studies were done at 54 sites across Australia, Europe, Israel, Japan and North America. The study was in children with confirmed venous thromboembolism who have been treated for at lea...
Source: Cardiophile MD - November 25, 2021 Category: Cardiology Authors: Prof. Dr. Johnson Francis Tags: General Cardiology Source Type: blogs
Fight Aging! Newsletter, November 22nd 2021
This study nicely illustrates the importance of the cellular metabolic state of myeloid cells: it highlights that not only the availability of glucose, but also its channeling into different pathways (glycolysis versus glycogen synthesis) contributes to maintaining proper myeloid function.
On the Ability of Redundant Blood Vessels to Lower Cardiovascular Mortality
https://www.fightaging.org/archives/2021/11/on-the-ability-of-redundant-blood-vessels-to-lower-cardiovascular-mortality/
A few strategies offer the possibility of growing additional redundant blood vessels, though this is far from rigorously p...
Source: Fight Aging! - November 21, 2021 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
On EV Tax Credits, What ’s Proponents’ Real Objective?
Scott Lincicome and Ilana BlumsackNestled in the ginormous,multi ‐trillion‐dollar“Build Back Better” package that just passed the House is a bonus for not just buying American, but buyingunion. In particular, congressional Democrats and the White House have proposed that electric vehicle consumersreceive a $12,500 refundable tax credit if they purchase an EV made at an American factory employing unionized workers. The subsidy declines, however, to $8000 if the vehicle is made at a non‐union U.S. plant and it drops another $500 if the car’s battery isn’t American‐made. Starting in 2027, moreov...
Source: Cato-at-liberty - November 19, 2021 Category: American Health Authors: Scott Lincicome, Ilana Blumsack Source Type: blogs
Studying the Comparative Biology of Aging in Rockfish Species
Rockfish species vary widely in lifespan. Some even exhibit negligible senescence, showing few signs of aging across the majority of their long life spans. When closely related species have divergent life spans, there is perhaps the opportunity to learn something of how metabolism determines longevity. Accordingly, researchers here report on their study of varied rockfish species, in search of the differences in the molecular biology of cells that lead to differences in life span and pace of aging.
In a new study, researchers compare the genomes of nearly two-thirds of the known species of rockfish that inhabit co...
Source: Fight Aging! - November 19, 2021 Category: Research Authors: Reason Tags: Daily News Source Type: blogs
Can Democracy Survive In The Absence of Health Care Security?
By MIKE MAGEE
In my course this fall at the President’s College at the University of Hartford, we began by exploring the word “right” at the intersection of health care services and the U.S. Constitution. But where we have ended up is at the crossroads of American history, considering conflicting federal and state law, and exploring Social Epidemiology, a branch of epidemiology that concentrates on the impact of the various social determinants of health on American citizens.
What makes the course timely and relevant is that we are uncovering a linkage between health and the construction or destruction of ...
Source: The Health Care Blog - November 17, 2021 Category: Consumer Health News Authors: Christina Liu Tags: Health Policy health care security Mike Magee Source Type: blogs
Breaking Up is Good to Do
By KIM BELLARD
Last week General Electric announced it was breaking itself up. GE is an American icon, part of America’s industrial landscape for the last 129 years, but the 21st century has not been kind to it. The breakup didn’t come as a complete surprise. Then later in the week Johnson and Johnson, another longtime American icon, also announced it would split itself up, and I thought, well, that’s interesting. When on the same day Toshiba said it was splitting itself up, I thought, hmm, I may have to write about this.
Healthcare is still in the consolidation phase, but there may be some lessons here for it....
Source: The Health Care Blog - November 16, 2021 Category: Consumer Health News Authors: Ryan Bose-Roy Tags: Finance The Business of Health Care Aetna conglomerates CVS-Aetna General Electric Johnson & Johnson Kim Bellard Optum Source Type: blogs
Here ’s How Psychologists Are Using Robots To Study The “Uncanny Valley”
By Emma L. Barratt
Mentioning the uncanny valley often brings one thing to mind — creepy dolls. The phenomenon, in which near-human-looking faces produce an inexplicable uneasy reaction in those who view them, was actually first described as an issue faced by roboticists. But the faces of dolls in particular are a cultural touchstone for uncanny feelings — at least in part due to their (over)use as a spooking-device in hundreds of horror movies over the years.
As such, psychological research has been conducted on the subtleties that non-human facial structure and expression can have on producing feelings of unea...
Source: BPS RESEARCH DIGEST - November 10, 2021 Category: Psychiatry & Psychology Authors: BPS Research Digest Tags: Cognition Perception Source Type: blogs
A Handheld X-Ray System: Interview with Evan Ruff and Gregory Kolovich, Co-Founders of OXOS Medical
OXOS Medical, a medtech spin-off out of Georgia Tech, has created the Micro C, an FDA cleared handheld X-ray system that is designed to image the distal extremities, from the shoulder to the hand and from the knee to the foot. The device is intended to prevent situations in which clinicians have to handle and operate large machinery to perform simple X-ray imaging of small bones in the extremities, and allows them to conduct imaging right at the point of care.
The device can be deployed during surgical procedures, and allows surgeons to more easily capture images that could be difficult to obtain using large, fixed equi...
Source: Medgadget - November 8, 2021 Category: Medical Devices Authors: Conn Hastings Tags: Exclusive Orthopedic Surgery Radiology Source Type: blogs
Digital Health Interests Of Pharma Giants Boehringer Ingelheim, Takeda, Astrazeneca, Amgen And Roche
With their extending reaches, resources and influence, pharmaceutical heavyweights have the potential to shape the digital health landscape to line up with their interests. And to have a better picture of where those interests lie, it is worth taking a look at what moves pharma giants are making in this sphere. With this in mind, we started a series of articles focusing on the digital health efforts of 14 global pharma companies.
The first article explored developments coming from Johnson & Johnson, Pfizer, Bayer and Novartis, while the second article investigated those coming from Merck, GlaxoSmithKline, AbbV...
Source: The Medical Futurist - November 4, 2021 Category: Information Technology Authors: Pranavsingh Dhunnoo Tags: TMF Artificial Intelligence in Medicine Digital Health Research Future of Pharma sleep patient empowerment pharmaceutics roche MySugr Astra-Zeneca DTx takeda Boehringer Ingelheim Amgen digitisation Quire.ai Renalytix Eko Source Type: blogs
Fight Aging! Newsletter, November 1st 2021
In conclusion, mitophagy pathways play an important role in maintaining physiological homeostasis, are involved in the mechanisms of aging and neurodegenerative disorders, and represent promising targets for the development of potential therapeutic agents aimed at regulating mitochondria quality control in neurons and glial cells. A significant number of molecules that induce or inhibit mitophagy are currently under consideration, which may be useful for testing hypotheses or developing drugs for the treatment of neurodegenerative diseases. The validation of promising drugs in animal and cell models, including neurons and ...
Source: Fight Aging! - October 31, 2021 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
