Digital therapeutics pioneer Akili Interactive Labs goes public, raising $150M+; trades down 49% first day
Akili Interactive is the latest company to go public via SPAC deal (Boston Business Journal): Boston’s Akili Interactive Labs Inc. is the latest Massachusetts-based company to go public after completing a reverse merger — in a year of market turmoil that saw few local firms passing the threshold between private and public status. Shares of Akili started trading on Monday on the Nasdaq Capital Market under the new ticker symbol “AKLI” after the company completed its previously announced reverse merger with Social Capital Suvretta Holdings Corp. I (Nasdaq: DNAA), a special purpose acquisition company, or SPAC. From t...
Source: SharpBrains - August 23, 2022 Category: Neuroscience Authors: SharpBrains Tags: Brain/ Mental Health Technology & Innovation Akili Interactive Labs AKLI cognitive Cognitive-impairment digital medicine digital therapeutics DNAA EndeavorRx neuropsychiatric neuropsychiatric diseases SPAC Source Type: blogs

Commentators and Journalists Weigh In On Digital Health And Related Privacy, Safety, Social Media And Security Matters. Lots Of Interesting Perspectives - August 23, 2022.
-----This weekly blog is to explore the news around the larger issues around Digital Health, data security, data privacy, AI / ML. technology, social media and related matters.I will also try to highlightADHA Propagandawhen I come upon it.Just so we keep count, the latest Notes from the ADHA Board were dated 6 December, 2018 and we have seen none since! It ’s pretty sad!Note: Appearance here is not to suggest I see any credibility or value in what follows. I will leave it to the reader to decide what is worthwhile and what is not! The point is to let people know what is being said / published that I have come upon.-----h...
Source: Australian Health Information Technology - August 23, 2022 Category: Information Technology Authors: Dr David G More MB PhD Source Type: blogs

The Macro View – Health, Economics, and Politics and the Big Picture. What I Am Watching Here And Abroad.
August 18, 2022 Edition-----The main issue, probably of the year, is the increasing tension across the Taiwan Strait with all sorts of worries about how conflict can be avoided and prosperity maintained at a reasonable level as tensions continue. And hopefully ease.The impact of climate change in Europe is really becoming obvious and worrying. I am not sure just how a realistic response is possible in any reasonable time.In OZ the PM has come back after a week off to have the Chinese Ambassador tell us we are a vassal and to just shut up and behave. Astonishing and serious stuff IMVHO.-----Major Issues.-----https://www.smh...
Source: Australian Health Information Technology - August 18, 2022 Category: Information Technology Authors: Dr David G More MB PhD Source Type: blogs

The New Deal and Recovery, Part 20: The Phantom Depression
George SelginIt was supposed to be a  debacle.As the Second World War drew to a  close, the nation’s leading economists feared that, once the armed services demobilized, at least 8 million men and women, perhaps many more, would be unemployed. That meant an unemployment rate of 12 percent—almost as high as the rate before Hitler raided the Low Countries, setting off the “ wartime boom.” If their forecasts were reliable, they meant that the postwar economy could end up being no closer to recovery than the prewar economy had been.A Worst ‐​Case ScenarioOf course, such dire predictions weren ’t unconditional....
Source: Cato-at-liberty - August 9, 2022 Category: American Health Authors: George Selgin Source Type: blogs

Fight Aging! Newsletter, August 8th 2022
In conclusion, aging research will benefit from a better definition of how specific regulators map onto age-dependent change, considered on a phenotype-by-phenotype basis. Resolving some of these key questions will shed more light on how tractable (or intractable) the biology of aging is. Does Acarbose Extend Life in Short Lived Species via Gut Microbiome Changes? https://www.fightaging.org/archives/2022/08/does-acarbose-extend-life-in-short-lived-species-via-gut-microbiome-changes/ Acarbose is one of a few diabetes medications shown to modestly slow aging in short-lived species. Researchers here take a...
Source: Fight Aging! - August 7, 2022 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

90 Hang in There Quotes to Renew Your Hope and Energy When You Need It
Sometimes you fall. You fail, make a mistake or just have a setback. And sometimes life’s just unfair. No matter what you try. These periods can go on for days or weeks. And sometimes even months. It’s tough. But it’s at these times you need to hang in there and keep moving forward. So in this post I’d like to help you with that and share 90 of the best hang in there quotes to renew your motivation and energy and shift negative thoughts to a positive mindset. And if you want even more motivation then check out this post with short, four word quotes and this one filled quotes on thankfulness. Uplifting Hang in Ther...
Source: Practical Happiness and Awesomeness Advice That Works | The Positivity Blog - August 5, 2022 Category: Consumer Health News Authors: Henrik Edberg Tags: Inspirational Quotes Personal Development Source Type: blogs

Interviews on Aspects of Aging with Judith Campisi and Dena Dubal
Today I'll point out a pair of interviews with researchers Judith Campisi and Dena Dubal, in which they discuss quite different aspects of aging. Campisi's research has a heavy focus on cellular senescence in aging. Cells become senescent constantly in the body, most because they hit the Hayflick limit on replication imposed upon the somatic cells that are the overwhelming majority of cells in our tissues. Cells can also become senescent because of damage, or encouraged into senescence by the signaling of other, nearby senescent cells. Once senescent, cells are normally quickly removed by the immune system or programmed ce...
Source: Fight Aging! - August 4, 2022 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs

Amazing Technologies Changing The Future Of Dermatology
Smart algorithms will soon diagnose skin cancer, dermatologists consult patients online, and 3D printers will print out synthetic skin to fight tissue shortages. There is a lot going on in dermatology, and medical professionals should prepare in time for the technological changes before they start swiping through the specialty. Let’s start by familiarising ourselves with the most amazing technologies changing the future of dermatology! Skin cancer is too common According to statistics from the WHO, currently, some 1.5 million non-melanoma skin cancers and 325,000 melanoma skin cancers occur globally each year. Data...
Source: The Medical Futurist - August 4, 2022 Category: Information Technology Authors: berci.mesko Tags: Future of Medicine Telemedicine & Smartphones 3d printing AI artificial intelligence digital Healthcare Innovation nanotechnology Personalized medicine robotics wearables GC1 dermatology Source Type: blogs

The Impact of COVID-19 on Shared Priorities for International Cooperation in Active and Healthy Aging
Discussion reflected on how the findings of the IDIH Digital Health Transformation Forum around the areas of Interoperability by Design, Data Governance, and Digital Inclusion might be impacted in a post-COVID-19 scenario. Joining us for the panel (moderated by Catalyst’s own Indu Subaiya and Matthew Holt) were Nancy Finn, Devon McGraw, Iana Simeonov, Dr. Mandy Salomon, and George Demiris. Nancy Finn is an author, healthcare journalist, educator, and activist who has been at the forefront of how technology can help patients. She’s the author of “e-Patients Live Longer: The Complete Guide to Managing Hea...
Source: The Health Care Blog - August 2, 2022 Category: Consumer Health News Authors: matthew holt Tags: Health Policy Health Tech elder care IDIH Project Source Type: blogs

Fight Aging! Newsletter, August 1st 2022
In this study, we used the recently released Infinium Mouse Methylation BeadChip to compare such epigenetic modifications in C57BL/6 (B6) and DBA/2J (DBA) mice. We observed marked differences in age-associated DNA methylation in these commonly used inbred mouse strains, indicating that epigenetic clocks for one strain cannot be simply applied to other strains without further verification. Interestingly, the CpGs with highest age-correlation were still overlapping in B6 and DBA mice and included the genes Hsf4, Prima1, Aspa, and Wnt3a. Furthermore, Hsf4, Aspa, and Wnt3a revealed highly significant age-associated DNA methyla...
Source: Fight Aging! - July 31, 2022 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

The Macro View – Health, Economics, and Politics and the Big Picture. What I Am Watching Here And Abroad.
July 28, 2022 Edition-----Sadly the war drags on, Biden seems to be pretty impotent on most policy fronts and the US seems to be heading into a recession. Not good,In the UK the choosing the next PM is off and running as the country and Europe are cooling down after a heatwave (for them) of biblical proportions!In OZ Parliament is meeting which is when the rubber will really hit the road as a new virus wave runs out of control still! We need to do more to control it as we realise just how bad long COVID is!-----Major Issues.-----https://www.afr.com/policy/economy/how-a-nobel-laureate-got-australian-economists-offside-...
Source: Australian Health Information Technology - July 28, 2022 Category: Information Technology Authors: Dr David G More MB PhD Source Type: blogs

The Evidence Keeps Coming On The Value Of Some Tech In Helping Mental Illness!
This release appeared last week:MEDIA RELEASEWednesday 13th July , 2022Virtual Reality App shown to reduce common phobias through clinical trial in New Zealand.Results from a New Zealand University trial suggest fresh hope for the estimated one-in-twelve people worldwide suffering from a fear of flying, needles, heights, spiders and dogs.The trial, led by Associate Professor Cameron Lacey, from the Department of Psychological Medicine, at the University of Otago, studied phobia patients using a headset and a smartphone app treatment programme – a combination of Virtual Reality (VR) 360-degree video exposure therapy and c...
Source: Australian Health Information Technology - July 27, 2022 Category: Information Technology Authors: Dr David G More MB PhD Source Type: blogs

Aubrey de Grey on Progress in SENS Rejuvenation Research
In this recent interview with Aubrey de Grey touches on a number of areas of progress made by the research and development community in recent years, projects that lead towards rejuvenation therapies based on the Strategies for Engineered Negligible Senescence (SENS). In the SENS view, supported by a very sizable literature accumulated over the past century, aging is caused by underlying processes of damage accumulation. What we think of as aging is a diverse collection of downstream consequences of that damage. Periodically repairing the underlying damage, allowing the normal maintenance of the body to continue as it woul...
Source: Fight Aging! - July 25, 2022 Category: Research Authors: Reason Tags: Daily News Source Type: blogs

Novartis' Sandoz Is Back In The Insulin Biosims Market. Can It Succeed?
Back in December 2018, the Sandoz division of Swiss pharmaceutical giant Novartis announced (see the full announcementHERE) " Sandoz enters into commercialization and supply agreement for insulin biosimilars " . It also revealed that Sandoz had entered a " commercialization and supply agreement with Gan& Lee " which it added was " a leading insulin supplier headquartered in China with more than 20 years ' experience in insulins and production capacity with attractive cost of goods sold (COGS) structures " .Few Americans have ever heard of Gan& Lee, although this year, at the American Diabetes Association ' s 82nd S...
Source: Scott's Web Log - July 22, 2022 Category: Endocrinology Tags: insulin analogs 2022 Biosimilar biosimilars generics insulin analogues Novartis Sandoz Source Type: blogs

The Macro View – Health, Economics, and Politics and the Big Picture. What I Am Watching Here And Abroad.
The objective most consistent with recent operations is to conquer Luhansk, Donetsk, and Kherson, with a view to their eventual annexation and Russification. But not only are they some way from achieving that (w ith much of Donetsk still in Ukrainian hands and the Russia position in Kherson highly contested) it would also require an explicit Ukrainian surrender for it to serve as the basis for a declaration of victory. That will not be forthcoming.-----https://www.afr.com/world/europe/how-britain-giggled-its-way-into-crisis-20220710-p5b0giHow Britain giggled its way into crisisBoris Johnson has exposed the costs of Britain...
Source: Australian Health Information Technology - July 21, 2022 Category: Information Technology Authors: Dr David G More MB PhD Source Type: blogs