Fight Aging! Newsletter, August 2nd 2021
This study aimed to determine the association between: (i) cognitive decline and bone loss; and (ii) clinically significant cognitive decline on Mini Mental State Examination (MMSE) over the first 5 years and subsequent fracture risk over the following 10 years. A total of 1741 women and 620 men aged ≥65 years from the population-based Canadian Multicentre Osteoporosis Study were followed from 1997 to 2013. Over 95% of participants had normal cognition at baseline. After multivariable adjustment, cognitive decline was associated with bone loss in women but not men. Approximately 13% of participants experienced sign...
Source: Fight Aging! - August 1, 2021 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Cryptocurrency Should Be Added to the U.S.-Japan Trade Deal
As the Biden administration begins to define its approach to international trade, and the Suga administration looks to further tighten cooperation with the United States, it may be worth reconsidering the exclusion of cryptocurrency from the U.S.-Japan trade deal. Substantial economic equities are at stake for both sides. (Source: The RAND Blog)
Source: The RAND Blog - July 28, 2021 Category: Health Management Authors: Sale Lilly; Scott W. Harold Source Type: blogs
All Too Much of the Demographic Data on Survival to Extreme Old Age is of Poor Quality
There are many challenges inherent in trying to learn something about aging through analysis of the demographics of extreme human longevity. First of all, there are just not that many supercentenarians, making it very hard to obtain enough data to make statistically sound inferences about health, tied as it is to the many complex and varied processes of aging. Secondly, and as illustrated by the paper here, much of the data that might otherwise be useful is of poor quality due to issues of fraud and lax recordkeeping.
The concentration of remarkable-aged individuals, within geographic regions or 'blue zones' or wi...
Source: Fight Aging! - July 26, 2021 Category: Research Authors: Reason Tags: Daily News Source Type: blogs
Z- score classification of coronary aneurysms in Kawasaki disease
Z-score is the standard deviation from coronary artery internal lumen diameter normalized for body surface area. AHA classification of coronary artery aneurysms based on Z-score is as follows [1]: 1. No involvement with Z score less than 2 always. 2. Dilatation only with Z scores from 2 to less than 2.5 or a decrease in Z score of 1 or more during follow up if it was less than 2 initially. 3. Small aneurysm with Z score of more than 2.5, but less than 5. 4. Medium aneurysm with Z score 5 or more, but less than 5 and absolute dimension less than 8 mm. 5. Large or giant aneurysm with Z score 10 or more or absolute dimension...
Source: Cardiophile MD - July 24, 2021 Category: Cardiology Authors: Prof. Dr. Johnson Francis Tags: Cardiology Source Type: blogs
A Taiwan Contingency and Japan's Counterstrike Debate
The United States and Japan could be drawn into a conflict in the event of Chinese aggression against Taiwan whether they like it or not. Allied defense planning could consider how Japan might further reinforce deterrence and if necessary improve its ability to contribute to the common defense. (Source: The RAND Blog)
Source: The RAND Blog - July 23, 2021 Category: Health Management Authors: Scott W. Harold; Satoru Mori Source Type: blogs
Health Care Should Go (Micro) Nuclear
By KIM BELLARD
I think of hospitals as the healthcare system’s nuclear power plants. They’re both big, complex, expensive to build, beset with heavy regulatory burdens, consistently major components of their respective systems (healthcare and electric generation) yet declining in number. Each is seen to offer benefits to many but also to pose unexpected risk to some.
Interestingly, there’s a “micro” trend for each, but aimed towards different ends.
Micro hospitals have been with us for several years. They usually have only around ten beds, along with an emergency room, lab and imaging.&...
Source: The Health Care Blog - July 21, 2021 Category: Consumer Health News Authors: Christina Liu Tags: Health Tech Kim Bellard nuclear power Source Type: blogs
Fight Aging! Newsletter, July 19th 2021
In this study, we developed the first epigenetic clock for domesticated sheep (Ovis aries), which can predict chronological age with a median absolute error of 5.1 months. We have discovered that castrated male sheep have a decelerated aging rate compared to intact males, mediated at least in part by the removal of androgens.
Furthermore, we identified several androgen-sensitive CpG dinucleotides that become progressively hypomethylated with age in intact males, but remain stable in castrated males and females. Comparable sex-specific methylation differences in MKLN1 also exist in bat skin and a range of mouse tissu...
Source: Fight Aging! - July 18, 2021 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
The Trump Administration Actually Thought Imported Cars Were a “National Security” Threat (and the Courts Would’ve Let ‘Em Get Away With It)
Inu Manak andScott LincicomeDo you drive an imported car or one made here by a foreign‐owned company? If so, you may be a serious threat to national security –if a long‐awaited report from the Trump administration is to be believed.No, really.Last week, the Department of Commerce finally released itsreport on U.S. imports of automobiles and certain automotive parts, as part of the Trump administration ’s 2018investigation pursuant to Section 232 of the Trade Expansion Act of 1962. While the report was submitted to the president on February 17, 2019, it was not published in the Federal Register, as the la...
Source: Cato-at-liberty - July 15, 2021 Category: American Health Authors: Inu Manak, Scott Lincicome Source Type: blogs
A Reminder that Merely Elevated Blood Pressure Still Increases Cardiovascular Disease Risk
The old guidelines for systolic blood pressure drew the line for increased risk of cardiovascular disease at 140 mmHg, with higher systolic blood pressure defined as hypertension. That dividing line was then moved down to 130 mmHg. In the past few years, further evidence has shown that elevated systolic blood pressure of 120 mmHg or above still produces increased risk, and that one shouldn't feel comfortable and safe in the 120-129 mmHg range. The risk of cardiovascular disease scales up with increasing blood pressure, and as noted here, also with the modern lifestyle choices leading to excess fat tissue, metabolic disease...
Source: Fight Aging! - July 12, 2021 Category: Research Authors: Reason Tags: Daily News Source Type: blogs
Fight Aging! Newsletter, July 12th 2021
In conclusion, our study demonstrated that elevated cumulative SBP or DBP was independently associated with increased risk of CVD in the Chinese population. Among participants with 15-year cumulative BP levels higher than the median, that is, 1970.8/1239.9 mmHg-year for cumulative SBP/DBP, which was equivalent to maintaining SBP/DBP level higher than 131/83 mmHg in 15 years, the CVD risk would increase significantly irrespective of whether or not the BP measurements at one examination was high. Our findings emphasize the importance of cumulative BP level in identifying individuals with high risk of CVD in the future.
...
Source: Fight Aging! - July 11, 2021 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Using Supercentenarian Data to Estimate Future Increases in Maximum Human Life Span
In today's research materials, scientists attempt to model future increases in maximum human longevity based on past data for supercentenarians, people aged 110 and older. This is an interesting exercise, but I think that all of the results have to be taken with a sizable grain of salt. Firstly, the data for extreme human outliers in longevity isn't great. A lot of it is of poor quality, and the portions that are well maintained do not include a sizable number of people. There are few survivors to such exceptional ages, which makes it hard to call any analysis of that data truly robust. This is a problem that afflicts all ...
Source: Fight Aging! - July 8, 2021 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs
The Fable of the Cats
George SelginThe comparison has by now been made so often that it may qualify as a platitude. I mean that between stablecoin issuers and “wildcat” banks, the fly‐by‐night scams that supposedly flooded the antebellum United States with notes nominally worth some stated amount of gold or silver, but actually worth little more than the rag paper they were made of.Such disreputable stuff, we keep hearing, is what “private” currency always tends to be like. The paper sort survived until federal authorities nationalized the nation’s paper money during the Civil War. And (we are told), digital currency will...
Source: Cato-at-liberty - July 6, 2021 Category: American Health Authors: George Selgin Source Type: blogs
How to Get Started Teaching English Abroad if You Have No Experience
Teaching English in another nation is an easy way to travel the globe without having to save thousands of dollars or have years of experience as a teacher. All you need is an online TEFL certificate and the ability to communicate in English. The rest is easy after you've checked those boxes.
When you begin teaching English in a foreign country, you will be able to spend your weekends exploring your new surroundings. If you pick China as your teaching location, for example, you will have the opportunity to travel across East Asia, including Japan, Taiwan, and South Korea.You may be able to save thousands of dollars by te...
Source: PickTheBrain | Motivation and Self Improvement - July 4, 2021 Category: Consumer Health News Authors: Esme Gelder Tags: career featured self education self-improvement success english abroad Source Type: blogs
Cardiology MCQs
Modified Blalock-Taussig shunt is:
End to side anastomosis of subclavian artery to a pulmonary artery
Side to side anastomosis of main pulmonary artery to aorta
Side to side anastomosis of subclavian artery to a pulmonary artery using a conduit
Anastomosis of superior vena cava to right pulmonary artery
Correct answer: 3. Side to side anastomosis of subclavian artery to a pulmonary artery using a conduit
In classic Blalock-Taussig shunt, the subclavian artery is divided and anastomosed to the pulmonary artery as an end to side anastomosis. In modified Blalock – Taussig shunt, a Gore – Tex graft is used to connect th...
Source: Cardiophile MD - July 4, 2021 Category: Cardiology Authors: Prof. Dr. Johnson Francis Tags: Cardiology MCQ DM / DNB Cardiology Entrance Source Type: blogs
Fight Aging! Newsletter, July 5th 2021
In conclusion, the findings suggest that DNAm GrimAge is a strong predictor of mortality independent of genetic influences.
Heart Failure Correlates with Increased Cancer Risk
https://www.fightaging.org/archives/2021/07/heart-failure-correlates-with-increased-cancer-risk/
Age-related disease results from the underlying cell and tissue damage that causes aging. Different people accumulate that damage at modestly different rates, the result of lifestyle choices and exposure to infectious disease. Thus the presence of a sufficient burden of damage to produce one age-related disease will be accompanied by a...
Source: Fight Aging! - July 4, 2021 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
