Study Uncovers: Brushing Teeth Twice Daily Reduces Heart Disease Risk
Conclusion The study came full circle, offering an emphatic conclusion. While a morning brush is a good start, brushing before bedtime takes the crown when it comes to preventing heart diseases. The act of brushing your teeth, so mundane yet so essential, emerges as a key soldier in the battle against heart disease. The findings beckon us to look at our toothbrushes differently – as tools of preventative care rather than just instruments of oral hygiene. The message is clear – taking care of our teeth could mean taking care of our hearts. After all, our health, as this study suggests, is a...
Source: The EMT Spot - July 4, 2023 Category: Emergency Medicine Authors: Michael Rotman, MD, FRCPC, PhD Tags: News Source Type: blogs

The Best ChatGPT Plugins: How To Add Browsing, Learning, Wolfram And More
ChatGPT plugins became available a few weeks ago and I have been testing them to see what they can do. They offer interesting new features from all walks of life, so let’s take a look at these new gadgets. What are ChatGPT plugins and how you can get them?  You can imagine these as apps on your phone: little extra programs that give ChatGPT extra skills.  How to enter the beta features?  You need to have GPT-4 access, which comes with the paid accounts. If you have GPT-4, click on your name on the bottom left, go to settings, click on beta features and allow them with the slider.  How t...
Source: The Medical Futurist - June 27, 2023 Category: Information Technology Authors: Andrea Koncz Tags: TMF artificial intelligence ChatGPT plugins digital health Medicine AI in healthcare AI in medicine Source Type: blogs

Six Different Ways: Ukraine Lessons for Japanese Defense Planners
Japanese leaders have already begun internalizing key lessons from Ukraine. But Japanese officials are silent on whether they are preparing for a short conflict or a long one. This matters because, as the Ukrainian war demonstrates, a protracted struggle could require different plans from the ones Japan is possibly making. (Source: The RAND Blog)
Source: The RAND Blog - June 23, 2023 Category: Health Management Authors: Jeffrey W. Hornung Source Type: blogs

Fight Aging! Newsletter, June 19th 2023
In conclusion, among Swedish middle-aged subjects, nearly two-thirds showed complete fatty degeneration of thymus on CT. Age-Related Dysfunction of Water Homeostasis https://www.fightaging.org/archives/2023/06/age-related-dysfunction-of-water-homeostasis/ Dehydration can be an issue in older people. As in every complex system in the body, the mechanisms by which hydration is regulated become dysfunctional with advancing age. Researchers here look at the brain region responsible for regulating some of the response to dehydration, cataloging altered gene expression in search of the more important mechan...
Source: Fight Aging! - June 18, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Analysis Of Over 10,000 Healthcare AI Patents Highlights Future Trends: Our New Study
We are thrilled to announce the recent publication of our new study, Forecasting Artificial Intelligence Trends in Health Care: Systematic International Patent Analysis in the Journal of Medical Internet Research AI (JMIR AI). Our study takes an interesting deep dive into healthcare AI patents from the last decade, analysing over 10,000 of them from 2012 to 2022. Through this exploration, we shed light on the growth trends, the direction AI innovation is heading in different medical specialties, and the potential future implications of AI and Machine Learning (ML) in healthcare. Our journey into the world of healthcare ...
Source: The Medical Futurist - June 15, 2023 Category: Information Technology Authors: Andrea Koncz Tags: TMF Artificial Intelligence in Medicine AI patents digital health patent analysis future Innovation machine learning AI in healthcare AI in medicine Source Type: blogs

Juicy Discovery: Can Japanese Plum Juice Beat Hypertension?
Conclusion: The Future Of Bainiku-Ekisu The next phase of Dr. Eguchi’s research intends to pinpoint the specific compounds in bainiku-ekisu responsible for its protective effects. He suggested that there might be two or three compounds acting in concert, resulting in additive or synergistic effects potentially lost in a pharmaceutical preparation. This research, sponsored by the National Institutes of Health and a research gift fund from Kobayashi Pharmaceutical Japan, might be an important step forward in managing hypertension and preventing cardiovascular diseases. Time will reveal whether the humble ...
Source: The EMT Spot - June 14, 2023 Category: Emergency Medicine Authors: Michael Rotman, MD, FRCPC, PhD Tags: News Source Type: blogs

Against Prioritizing Environmentalism Over Human Health
It is fair to say that the mainstream of environmentalism prioritizes conservation of the environment over human comfort and health. Environmental concerns are high on the list of objections raised against treating aging as a medical condition, because most people believe that this will lead to a larger population, and also believe that population increases cannot occur without degrading the environment. Both of those beliefs are false, the latter evidently so given the improvements in the environment created since the 1950s, over a period of considerable population growth. Models strongly suggest that the future is one in...
Source: Fight Aging! - June 12, 2023 Category: Research Authors: Reason Tags: Of Interest Source Type: blogs

Fight Aging! Newsletter, June 12th 2023
In this study, we investigated the effect of NXP032 on neurovascular stabilization through the changes of PECAM-1, PDGFR-β, ZO-1, laminin, and glial cells involved in maintaining the integrity of the blood-brain barrier (BBB) in aged mice. NXP032 was orally administered daily for 8 weeks. Compared to young mice and NXP032-treated mice, 20-month-old mice displayed cognitive impairments in Y-maze and passive avoidance tests. NXP032 treatment contributed to reducing the BBB damage by attenuating the fragmentation of microvessels and reducing PDGFR-β, ZO-1, and laminin expression, thereby mitigating astrocytes and microglia ...
Source: Fight Aging! - June 11, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

CADDAC ’S ADHD And Substance Use Disorder Peer-Led Support Groups
This is great news by CADDAC and Health Canada to create ADHD and substance use disorder peer-led support groups in the fall. They’re looking now for peer support facilitators now with lived experience who are willing to be trained and run them. Will be offered a stipend for their time. Hope people with ADHD ask their MLAs to get provincial health departments to create ADHD and substance use disorder (SUD) peer-led support groups too. ADHD people are 4-8 times + more likely to have SUD. Provinces should also require ALL rehabs to screen for ADHD. Every BC rehab I’ve asked at community events in Vancouver does n...
Source: Adult ADD Strengths - June 10, 2023 Category: Psychiatry Authors: Pete Quily Tags: ADD / ADHD Addictions Source Type: blogs

Investigating the Gut Microbiome of Centenarians
The extensive, well-funded search for genetic differences in long-lived individuals has found little: small effect sizes, and only a few genetic variants that replicate in multiple studies. Will the search for gut microbiome differences characteristic of long-lived individuals do any better? This remains to be seen, as the research community is only a few studies into this exercise, and it takes more than a few studies to build a consensus. The evidence to date suggests cautiously optimism, as researchers do see differences in microbial species abundance in exceptionally old individuals versus merely old individuals. As no...
Source: Fight Aging! - June 7, 2023 Category: Research Authors: Reason Tags: Daily News Source Type: blogs

How the Arts transform our Brains, Bodies, and Minds
One of my favorite sayings comes from David Thoreau: “My life has been the poem I would have writ / But I could not both live and utter it.” It speaks to the way that life and art are intertwined, and how we gain so much from living life with a sense of beauty and aesthetics in mind. There are many ways art infuses my own life—from singing and playing guitar to reading novels and attending plays, which all help to improve my mood and enhance my sense of wonder with the world. Probably, neuroaesthetics many of you feel the same way. Some of you may have felt you’ve even been saved by art. Now, a new book, Your Brai...
Source: SharpBrains - May 31, 2023 Category: Neuroscience Authors: Greater Good Science Center Tags: Brain/ Mental Health Education & Lifelong Learning art neuroaesthetics Your Brain on Art Source Type: blogs

Intratumoral Bacteria as an Injectable Anti-Cancer Treatment
Scientists at the Japan Advanced Institute of Science and Technology in Ishikawa, Japan have developed an anti-cancer treatment that consists of bacteria that are naturally found inside some tumors. Isolating and then injecting these bacteria into existing tumors appears to provoke a strong immune response that can lead to tumor destruction, without the need for advanced techniques such as bacterial genetic engineering or complex drug delivery. The concept of using bacteria to target tumors is not new, but typically it is studied in the context of using the bacteria to deliver a drug or using genetically engineered bacteri...
Source: Medgadget - May 19, 2023 Category: Medical Devices Authors: Conn Hastings Tags: Medicine Oncology JAIST Source Type: blogs

When Mother's Day is Tough
Mother ' s Day is a holiday that is marked world-wide. Countries such as the United States, Canada, The UK, Australia, China and Japan, just to name a few, highlight the day on their yearly calendar.Historically, Mother ' s Day has been a day where children and other family members honor mothers who are nurturing and supportive. For some, it is a day of celebration, of expressing one ' s love and appreciation for to a mother - or someone who is like a mother. The day is met with happiness and the sharing of joyous memories -  and the anticipation of good times to come.However, for others, Mother ' s Day is not so easy...
Source: Dr. Deborah Serani - May 12, 2023 Category: Psychiatry & Psychology Tags: caregiving grief holidays mother ' s day parenting Source Type: blogs

Nursing the Nation and the World
Nurses are everywhere. They are legion. The ubiquitous nurse is present in the care of children, the elderly, the disabled, and the dying. Nurses don ' t shy away from responsibility — they embrace it. Nurses run towards the metaphorical fire. Just as firefighters rush into burning buildings and police officers run towards the active shooter, nurses don their gloves and deal with the sputum, the blood, the pus, the emesis, the feces, and the urine — body fluids be damned, th ere ' s work to do and nurses do it. The Ubiquitous NurseWhere would the country be without nurses? Without nurses, the healthcare system wou...
Source: Digital Doorway - May 8, 2023 Category: Nursing Source Type: blogs

Fight Aging! Newsletter, May 8th 2023
In conclusion, NAT mitigated age-associated cerebral injury in mice through gut-brain axis. The findings provide novel evidence for the effect of NAT on anti-aging, and highlight the potential application of NAT as an effective intervention against age-related diseases. Retinal Cell Reprogramming Restores Vision in Non-Human Primate Study https://www.fightaging.org/archives/2023/05/retinal-cell-reprogramming-restores-vision-in-non-human-primate-study/ Early applications of in vivo cellular reprogramming to medicine are cautiously focused on retinal regeneration. The eye is as close to an isolated system...
Source: Fight Aging! - May 7, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs