Narratives of Space and Time in Multiple Sclerosis Diagnosis
This article examines the complexity of narratives of space and time which support the diagnosis of multiple sclerosis, and the consequences for patients disadvantaged by deficits in social cognition or socioeconomic status in areas relating to literacy. In the context of demonstrating the significance of narratives of space and time in the diagnostic process for multiple sclerosis, the article discusses new strategies for treatment that engage the arts and humanities and presents a brief history of the disease and current diagnostic criteria, before discussing the MS Society of Great Britain and Ireland's awareness and fu...
Source: Perspectives in Biology and Medicine - April 25, 2024 Category: Medical Ethics Authors: Paula Leverage Source Type: research
Outbreak of invasive Group A streptococcus disease in a nursing home in Ireland in February 2023 caused by emm type 18
We describe the management of an iGAS outbreak involving three nursing home residents in Ireland in early 2023. A regional Department of Public Health was notified of an iGAS case in a nursing home resident in January 2023. When two further cases among residents were notified 7 days later, an outbreak was declared. Surveillance for GAS/iGAS infection in residents and staff was undertaken. The site was visited to provide infection prevention and control (IPC) support. Isolates wereemm typed. A total of 38 residents and 29 staff in contact with resident cases were provided with antibiotic chemoprophylaxis. Seven additi...
Source: Eurosurveillance - April 25, 2024 Category: Infectious Diseases Authors: Ciara Carroll, Mary Meehan, Roisin Connolly, Jayne Prendergast, Colette Magnone, Aine Meehan, Chantal Migone, Keith Ian Quintyne, Caroline Carpenter, Helen Byrne, Robert Cunney and Paul Mullane Source Type: research
Disparities in Access to Bariatric Surgery in North Carolina
This study sought to identify factors that contribute to disparities in access to bariatric surgery in North Carolina (NC).METHODS: Using the rate of bariatric surgery in the county with the best health outcome as the reference, we calculated the Surgical Equity Index (SEI) in the remaining counties in NC.RESULTS: Approximately 2.95 million individuals (29%) were obese in NC. There were 992 (.5%) bariatric procedures performed on a population of 194 209 individuals with obesity in the Reference County (RC). The mean SEI for bariatric surgery in NC was .47 (SD .17, range .15-.95). A statistically significant difference was ...
Source: The American Surgeon - April 23, 2024 Category: Surgery Authors: Jan H Wong Ashley E Burch Eric J DeMaria Walter J Pories William D Irish Source Type: research
Disparities in Access to Bariatric Surgery in North Carolina
This study sought to identify factors that contribute to disparities in access to bariatric surgery in North Carolina (NC).METHODS: Using the rate of bariatric surgery in the county with the best health outcome as the reference, we calculated the Surgical Equity Index (SEI) in the remaining counties in NC.RESULTS: Approximately 2.95 million individuals (29%) were obese in NC. There were 992 (.5%) bariatric procedures performed on a population of 194 209 individuals with obesity in the Reference County (RC). The mean SEI for bariatric surgery in NC was .47 (SD .17, range .15-.95). A statistically significant difference was ...
Source: The American Surgeon - April 23, 2024 Category: Surgery Authors: Jan H Wong Ashley E Burch Eric J DeMaria Walter J Pories William D Irish Source Type: research
Psychiatry and psychotherapy: the science of sitting with uncertainty
ConclusionAmbiguity and uncertainty in the setting of partial knowledge presents psychiatry with a challenge, yes; but it also enables psychiatry to be innovative in its approach, and to address the complexities of the human condition in a way that is unique and unparalleled within the field of medicine. (Source: Irish Journal of Medical Science)
Source: Irish Journal of Medical Science - April 23, 2024 Category: General Medicine Source Type: research
REPAIRS Delphi: A UK and Ireland Consensus Statement on the Management of Infected Arterial Pseudoaneurysms Secondary to Groin Injecting Drug Use
This study was designed to establish consensus to promote better management of these patients, drawing on the expert experience of those in a location with a high prevalence of illicit drug use. (Source: European Journal of Vascular and Endovascular Surgery)
Source: European Journal of Vascular and Endovascular Surgery - April 23, 2024 Category: Surgery Authors: Caitlin S. MacLeod, John Nagy, Andrew Radley, Faisel Khan, Nikolas Rae, Michael S.J. Wilson, Stuart A. Suttie, REPAIRS Collaborative Source Type: research
Gender Difference in sidE eFfects of ImmuNotherapy: a possible clue to optimize cancEr tReatment (G-DEFINER): study protocol of an observational prospective multicenter study
Acta Oncol. 2024 Apr 21;63:213-219. doi: 10.2340/1651-226X.2024.24179.ABSTRACTBACKGROUND: Immune checkpoint inhibitors (ICIs) have significantly improved outcomes in various cancers. ICI treatment is associated with the incidence of immune-related adverse events (irAEs) which can affect any organ. Data on irAEs occurrence in relation to sex- differentiation and their association with gender-specific factors are limited.AIMS: The primary objective of the G-DEFINER study is to compare the irAEs incidence in female and male patients who undergo ICI treatment. Secondary objectives are: to compare the irAEs incidence in pre- an...
Source: Acta Oncologica - April 22, 2024 Category: Cancer & Oncology Authors: Rosalba Miceli Hanna Eriksson Giuseppe Lo Russo Salvatore Alfieri Maria Moksnes Bjaan æs Filippo Pietrantonio Loris De Cecco Arsela Prelaj Claudia Proto Johan Franz én Deirdre McDonnell Jos é Javier Berenguer Pina Teresa Beninato Laura Mazzeo Patrizia Source Type: research
Gender Difference in sidE eFfects of ImmuNotherapy: a possible clue to optimize cancEr tReatment (G-DEFINER): study protocol of an observational prospective multicenter study
Acta Oncol. 2024 Apr 21;63:213-219. doi: 10.2340/1651-226X.2024.24179.ABSTRACTBACKGROUND: Immune checkpoint inhibitors (ICIs) have significantly improved outcomes in various cancers. ICI treatment is associated with the incidence of immune-related adverse events (irAEs) which can affect any organ. Data on irAEs occurrence in relation to sex- differentiation and their association with gender-specific factors are limited.AIMS: The primary objective of the G-DEFINER study is to compare the irAEs incidence in female and male patients who undergo ICI treatment. Secondary objectives are: to compare the irAEs incidence in pre- an...
Source: Acta Oncologica - April 22, 2024 Category: Cancer & Oncology Authors: Rosalba Miceli Hanna Eriksson Giuseppe Lo Russo Salvatore Alfieri Maria Moksnes Bjaan æs Filippo Pietrantonio Loris De Cecco Arsela Prelaj Claudia Proto Johan Franz én Deirdre McDonnell Jos é Javier Berenguer Pina Teresa Beninato Laura Mazzeo Patrizia Source Type: research
Gender Difference in sidE eFfects of ImmuNotherapy: a possible clue to optimize cancEr tReatment (G-DEFINER): study protocol of an observational prospective multicenter study
Acta Oncol. 2024 Apr 21;63:213-219. doi: 10.2340/1651-226X.2024.24179.ABSTRACTBACKGROUND: Immune checkpoint inhibitors (ICIs) have significantly improved outcomes in various cancers. ICI treatment is associated with the incidence of immune-related adverse events (irAEs) which can affect any organ. Data on irAEs occurrence in relation to sex- differentiation and their association with gender-specific factors are limited.AIMS: The primary objective of the G-DEFINER study is to compare the irAEs incidence in female and male patients who undergo ICI treatment. Secondary objectives are: to compare the irAEs incidence in pre- an...
Source: Acta Oncologica - April 22, 2024 Category: Cancer & Oncology Authors: Rosalba Miceli Hanna Eriksson Giuseppe Lo Russo Salvatore Alfieri Maria Moksnes Bjaan æs Filippo Pietrantonio Loris De Cecco Arsela Prelaj Claudia Proto Johan Franz én Deirdre McDonnell Jos é Javier Berenguer Pina Teresa Beninato Laura Mazzeo Patrizia Source Type: research
Gender Difference in sidE eFfects of ImmuNotherapy: a possible clue to optimize cancEr tReatment (G-DEFINER): study protocol of an observational prospective multicenter study
Acta Oncol. 2024 Apr 21;63:213-219. doi: 10.2340/1651-226X.2024.24179.ABSTRACTBACKGROUND: Immune checkpoint inhibitors (ICIs) have significantly improved outcomes in various cancers. ICI treatment is associated with the incidence of immune-related adverse events (irAEs) which can affect any organ. Data on irAEs occurrence in relation to sex- differentiation and their association with gender-specific factors are limited.AIMS: The primary objective of the G-DEFINER study is to compare the irAEs incidence in female and male patients who undergo ICI treatment. Secondary objectives are: to compare the irAEs incidence in pre- an...
Source: Acta Oncologica - April 22, 2024 Category: Cancer & Oncology Authors: Rosalba Miceli Hanna Eriksson Giuseppe Lo Russo Salvatore Alfieri Maria Moksnes Bjaan æs Filippo Pietrantonio Loris De Cecco Arsela Prelaj Claudia Proto Johan Franz én Deirdre McDonnell Jos é Javier Berenguer Pina Teresa Beninato Laura Mazzeo Patrizia Source Type: research
Gender Difference in sidE eFfects of ImmuNotherapy: a possible clue to optimize cancEr tReatment (G-DEFINER): study protocol of an observational prospective multicenter study
Acta Oncol. 2024 Apr 21;63:213-219. doi: 10.2340/1651-226X.2024.24179.ABSTRACTBACKGROUND: Immune checkpoint inhibitors (ICIs) have significantly improved outcomes in various cancers. ICI treatment is associated with the incidence of immune-related adverse events (irAEs) which can affect any organ. Data on irAEs occurrence in relation to sex- differentiation and their association with gender-specific factors are limited.AIMS: The primary objective of the G-DEFINER study is to compare the irAEs incidence in female and male patients who undergo ICI treatment. Secondary objectives are: to compare the irAEs incidence in pre- an...
Source: Acta Oncologica - April 22, 2024 Category: Cancer & Oncology Authors: Rosalba Miceli Hanna Eriksson Giuseppe Lo Russo Salvatore Alfieri Maria Moksnes Bjaan æs Filippo Pietrantonio Loris De Cecco Arsela Prelaj Claudia Proto Johan Franz én Deirdre McDonnell Jos é Javier Berenguer Pina Teresa Beninato Laura Mazzeo Patrizia Source Type: research
Multiple introductions of monkeypox virus to Ireland during the international mpox outbreak, May 2022 to October 2023
ConclusionWe provide insights into the international transmission dynamics supporting multiple introductions of MPXV into Ireland. Such information supported the implementation of evidence-informed public health control measures.PMID:38639093 | PMC:PMC11027473 | DOI:10.2807/1560-7917.ES.2024.29.16.2300505 (Source: Euro Surveill)
Source: Euro Surveill - April 19, 2024 Category: Infectious Diseases Authors: Gabriel Gonzalez Michael Carr Tom ás M Kelleher Emer O'Byrne Weronika Banka Brian Keogan Charlene Bennett Geraldine Franzoni Patrice Keane Cliona Kenna Luke W Meredith Nicola Fletcher Jose Maria Urtasun-Elizari Jonathan Dean Ciaran Browne Fiona Lyons Bre Source Type: research
Risk factors associated with the development of osteoradionecrosis (ORN) in Head and Neck cancer patients in Ireland: A 10-year retrospective review
CONCLUSION: This is the first retrospective study of ORN in HNC patients in Ireland over 10-year period. ORN incidence was extremely low (4.4%). As patients reported high smoking/alcohol use and poor dental attendance pre-diagnosis, this suggests intensive dental intervention pre/post-diagnosis contributed to low ORN rates. Mandibular surgery pre-RT increased risk of developing ORN at the surgical site. Therefore, we recommend future treatment planning should contour the surgical site, designating it an organ at risk (OAR), assigning a dose constraint, where oncologically possible, with emphasis on reducing the hot-spot to...
Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology - April 19, 2024 Category: Radiology Authors: Kathleen T Fitzgerald Ciara Lyons Andrew England Mark F McEntee Annemarie Devine Theresa O'Donovan Eleanor O'Sullivan Source Type: research
Holding the Guardrails on Involuntary Commitment
Hastings Cent Rep. 2024 Mar;54(2):8-11. doi: 10.1002/hast.1574.ABSTRACTIn response to the increasing number of mentally ill people experiencing homelessness, some policy-makers have called for the expanded use of involuntary commitment, even for individuals who are not engaging in behaviors that are immediately life-threatening. Yet there is no evidence that involuntary commitment offers long-term benefits, and significant reasons to believe that expanding the practice will cause harm. In addition, these proposals ignore research showing that most people with mental illness have the capacity to make medical decisions for t...
Source: The Hastings Center Report - April 19, 2024 Category: Medical Ethics Authors: Carl H Coleman Source Type: research
Multiple introductions of monkeypox virus to Ireland during the international mpox outbreak, May 2022 to October 2023
ConclusionWe provide insights into the international transmission dynamics supporting multiple introductions of MPXV into Ireland. Such information supported the implementation of evidence-informed public health control measures.PMID:38639093 | PMC:PMC11027473 | DOI:10.2807/1560-7917.ES.2024.29.16.2300505 (Source: Euro Surveill)
Source: Euro Surveill - April 19, 2024 Category: Infectious Diseases Authors: Gabriel Gonzalez Michael Carr Tom ás M Kelleher Emer O'Byrne Weronika Banka Brian Keogan Charlene Bennett Geraldine Franzoni Patrice Keane Cliona Kenna Luke W Meredith Nicola Fletcher Jose Maria Urtasun-Elizari Jonathan Dean Ciaran Browne Fiona Lyons Bre Source Type: research
