Implementation of a New Model of Care for Supporting Long-term Medication Adherence
Conditions: Medication Initiation for Long-term Conditions Interventions: Behavioral: myCare Start Sponsors: University of Geneva, Switzerland; University of Basel; Fundaci ó Sant Joan de Déu; pharmaSuisse, Switzerland; Center for Primary Care and Public Health (Unisante), University of Lausanne, Switzerland; University of Bern Enrolling by invitation (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 5, 2024 Category: Research Source Type: clinical trials

Slow-SPEED-NL: Slowing Parkinson's Early Through Exercise Dosage-Netherlands
Conditions: Parkinson Disease; Prodromal Stage; Neurodegenerative Diseases; Parkinsonian Disorders; REM Sleep Behavior Disorder; Basal Ganglia Diseases; Central Nervous System Diseases; Synucleinopathies; Nervous System Diseases; Cerebral Disorder; Brain Diseases Interventions: Behavioral: Increase of physical activity volume and intensity with the use of a motivational smartphone application Sponsors: Radboud University Medical Center; Stichting ParkinsonNL; ZonMw: The Netherlands Organisation for Health Research and Development; Michael J. Fox Foundation for Parkinson ' s Research; PARKINSONS UK; Cure Parkinsons; Edmond ...
Source: ClinicalTrials.gov - January 5, 2024 Category: Research Source Type: clinical trials

Vitamin E-enriched medium cross-linked polyethylene in total knee arthroplasty (VIKEP): clinical outcome, oxidation profile, and wear analysis in comparison to standard polyethylene —study protocol for a randomized controlled trial
DiscussionThe comparison between MXE and the standard gliding surface in this study will provide clinical data to confirm preceding biomechanical results in vivo. It is assumed that material-related differences will be identified, i.e., that the new material will be less sensitive to wear and creep. This may become obvious in biomechanical analyses of retrieved implants from revised patients and in radiologic analyses.Trial registrationClinicalTrials.gov, NCT04618016. Registered 27 October 2020,https://clinicaltrials.gov/study/NCT04618016?term=vikep&checkSpell=false&rank=1.All items from the World Health Organizati...
Source: Trials - January 5, 2024 Category: Research Source Type: clinical trials

Protocol of a monocentric, double-blind, randomized, superiority, controlled trial evaluating the effect of in-prison OROS-methylphenidate vs. placebo treatment in detained people with attention-deficit hyperactivity disorder (BATIR)
This study is a phase III, double-blinded, randomized, superiority, controlled trial of OROS-MPHvs. placebo. After randomization, the participants will receive 3 months of treatment with OROS-MPH or placebo (1:1 ratio) while incarcerated. Upon release, all participants will be offered the treatment (OROS-MPH) for 1 year but will remain blinded to their initial study group. The study will be conducted at the Division of Prison Health, Geneva, Switzerland, among incarcerated men (n = 150). Measures will include (1) investigator-rated ADHD symptoms, (2) acute events collected by the medical and prison teams, (3) assessment of...
Source: Trials - January 4, 2024 Category: Research Source Type: clinical trials

Efficacy and Safety of MOX/ALB Co-administration in SAC
Conditions: Trichuriasis; Ascariasis; Hookworm Infections Interventions: Drug: Moxidectin 2 mg Oral Tablet; Drug: Albendazole 400 mg Oral Tablet; Drug: Placebo MOX; Drug: Placebo ALB Sponsors: Jennifer Keiser; Public Health Laboratory Ivo de Carneri Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 3, 2024 Category: Research Source Type: clinical trials

Preoperative supine time for adrenal venous sampling: a prospective randomized controlled trial
This study will help to understand whether the length of preoperative supine time would affect the diagnostic efficacy of AVS and thus help to formulate a more reasonable AVS procedure.Trial registrationClinicalTrials.gov NCT05658705. Registered on 10 September 2022. (Source: Trials)
Source: Trials - January 2, 2024 Category: Research Source Type: clinical trials

Efficacy, Safety and Acceptability of Ivermectin ODT in PSAC
Conditions: Trichuriasis; Ascariasis; Hookworm Infections Interventions: Drug: Ivermectin 1.5 mg ODT; Drug: Ivermectin 3 mg Oral Tablet; Drug: Albendazole 400 mg Oral Tablet; Drug: Placebo IVM ODT Sponsors: Jennifer Keiser; Public Health Laboratory Ivo de Carneri Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - December 28, 2023 Category: Research Source Type: clinical trials

Introduction of Preconception Care Through Public Health System for Improving MNCH & FP
Conditions: Feasibility; Acceptability of Health Care Interventions: Behavioral: Preconception care (PCC) Sponsors: International Centre for Diarrhoeal Disease Research, Bangladesh; Directorate General of Family Planning, Minstry of Health and Family Welfare, Bangladesh; Directorate General of Health Services, Minstry of Health and Family Welfare, Bangladesh; UNFPA; FCDO Active, not recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - December 19, 2023 Category: Research Source Type: clinical trials

Effect of denosumab on glucose metabolism in postmenopausal osteoporotic women with prediabetes: a study protocol for a 12-month multicenter, open-label, randomized controlled trial
This study aims to provide evidence on the efficacy of denosumab on glucose metabolism in postmenopausal women with osteoporosis and prediabetes. The results derived from this clinical trial may provide insight into the potential of denosumab in preventing T2D in high-risk populations.Trial registrationThis study had been registered in the Chinese Clinical Trials Registry. Registration number: ChiCTR2300070789 on April 23, 2023.https://www.chictr.org.cn. (Source: Trials)
Source: Trials - December 18, 2023 Category: Research Source Type: clinical trials

Physical Activity Coaching in Patients With Post-COVID-19
Conditions: Post-COVID-19 Syndrome Interventions: Behavioral: Self-monitoring; Behavioral: Goal setting and review; Behavioral: Education; Behavioral: Feedback; Behavioral: Contact; Behavioral: Exercise; Behavioral: Report; Behavioral: Social support; Behavioral: Group activities; Behavioral: World Health Organization recommendations for being physically active Sponsors: University of Alcala; Professional College of Physiotherapists of the Community of Madrid Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - December 12, 2023 Category: Research Source Type: clinical trials

Study protocol for a randomized controlled trial of RealConsent2.0: a web-based intervention to promote prosocial alcohol-involved bystander behavior in young men
DiscussionRealConsent2.0 is the first web-based intervention for young men that encourages and teaches skills to engage in prosocial bystander behavior to prevent SV while intoxicated. This is also the first study to assess the proximal effect of alcohol on bystander behavior via a VR environment.Trial registrationClinicaltrials.gov, NCT04912492. Registered on 05 February 2021 (Source: Trials)
Source: Trials - December 12, 2023 Category: Research Source Type: clinical trials

Evaluation of a Group-based Parenting Intervention for Early Childhood Development
Conditions: Child Development Interventions: Behavioral: Parenting program Sponsors: Harvard School of Public Health (HSPH); ChildFund Kenya; Conrad N. Hilton Foundation; B&M Consult Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - December 11, 2023 Category: Research Source Type: clinical trials

Female Community Health Volunteers Led Hypertension Prevention and Control in Nepal
Conditions: Hypertension Interventions: Behavioral: Intervention Group Sponsors: Kathmandu University School of Medical Sciences; World Health Organization; Institute for Implementation Science and Health Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - December 11, 2023 Category: Research Source Type: clinical trials

Social Transfers for Exclusive Breastfeeding in Brazil
Conditions: Breast Feeding, Exclusive; Breastfeeding; Development, Child; Development, Infant Interventions: Behavioral: Social Transfer Sponsors: Swiss Tropical& Public Health Institute; University of Sao Paulo; University of Basel; Swiss National Science Foundation Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - December 6, 2023 Category: Research Source Type: clinical trials

Development and Evaluation of Virtual Reality Experiences for Cognitive Stimulation at the Sociosanitary Center El Carme
Conditions: Cognitive Dysfunction; Mild Cognitive Impairment Interventions: Device: Virtual Reality Cognitive Stimulation Program Sponsors: Badalona Serveis Assistencials; Public Health Agency of Barcelona; Reality Telling SL Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - December 4, 2023 Category: Research Source Type: clinical trials