International Medicine & Public Health Clinical Trials This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

An observer-blinded, cluster randomised trial of a typhoid conjugate vaccine in an urban South Indian cohort
We present here the protocol of a cluster randomised vaccine trial to assess the impact of introducing TyphiBEV ® vaccine to those between 1 and 30 years of age in a high-burden setting.MethodsThe primary objective is to determine the relative and absolute rate reduction of symptomatic, blood-culture-confirmedS. Typhi infection among participants vaccinated with TyphiBEV ® in vaccine clusters compared with the unvaccinated participants in non-vaccine clusters. The study population is residents of 30 wards of Vellore (a South Indian city) with participants between the ages of 1 and 30 years who provide informed consent....
Source: Trials - August 3, 2023 Category: Research Source Type: clinical trials

Effectiveness of a community health worker-led low-sodium salt intervention to reduce blood pressure in rural Bangladesh: protocol for a cluster randomized controlled trial
DiscussionRecent large clinical trials of LSSS in China and India have shown not only blood pressure improvements, but also stroke, major cardiac event, and all-cause mortality reductions. Nevertheless, how to best translate this intervention to population-level effectiveness remains unclear. Our study would test whether a community health worker-based program could be effectively used to disseminate LSSS and achieve measurable blood pressure benefits.Trial registrationClinicalTrials.gov NCT05425030. Registered on June 21, 2022. (Source: Trials)
Source: Trials - July 27, 2023 Category: Research Source Type: clinical trials

Impact of Reducing Colistin Use on Colistin Resistance in Humans and Poultry in Indonesia
Conditions: Colonization, Asymptomatic; Colistin; Mcr-1; Antimicrobial Resistance Intervention: Other: screening Sponsors: Erasmus Medical Center; Indonesia University; Center For Indonesian Veterinary Analytical Studies; Utrecht University; Institute of Tropical Medicine; University of Calgary; Directorate of Veterinary Public Health, Ministry of Agriculture Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - July 25, 2023 Category: Research Source Type: clinical trials

Lower Extremity Amputations in Persons With Diabetes Mellitus in the Netherlands
Conditions: Lower Extremity Amputations; Diabetes Mellitus Intervention: Procedure: lower extremity amputation Sponsors: University Medical Center Groningen; Isala; Innofeet; Vektis health care information center; National Institute for Public Health and the Environment (RIVM) Active, not recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - July 11, 2023 Category: Research Source Type: clinical trials