International Medicine & Public Health Clinical Trials This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Brief Digital Intervention to Increase COVID-19 Vaccination Among Individuals With Anxiety or Depression
Conditions: Misinformation; Vaccine Hesitancy; Anxiety; Depression; COVID-19 Interventions: Behavioral: Attitudinal inoculation; Behavioral: Cognitive-behavioral therapy-informed intervention; Behavioral: Conventional public health messaging Sponsors: City University of New York, School of Public Health; University of North Carolina, Chapel Hill Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - November 7, 2023 Category: Research Source Type: clinical trials

Tolerability and Immunogenicity of a Single 40-ug Dose of rBV A/B for the Production of BabyBIG ®
Conditions: Botulism Interventions: Biological: rBV A/B Sponsors: California Department of Public Health Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - November 2, 2023 Category: Research Source Type: clinical trials

Diagnostic Innovations for Pediatric Tuberculosis in Bolivia
Conditions: Tuberculosis Interventions: Diagnostic Test: Quantiferon Gold; Diagnostic Test: HIV serology; Diagnostic Test: Respiratory secretion culture (sputum or gastric aspirate_; Diagnostic Test: Chest radiograph; Diagnostic Test: Lung ultrasound; Diagnostic Test: cell free DNA test Sponsors: Tulane University; Asociacion Benefica Prisma; Universidad Peruana Cayetano Heredia; Johns Hopkins Bloomberg School of Public Health Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - November 2, 2023 Category: Research Source Type: clinical trials

Personalised Medicine in the Identification of Preclinical Cognitive Impairment. Development of a Predictive Risk Model
Conditions: Cognitive Dysfunction Sponsors: Instituto de Salud Carlos III; Instituto de Investigaci ón Biomédica de Salamanca; Carlos III Health Institute; Universidad Complutense de Madrid; Biomedical Research Networking Centre on Frailty and Healthy Ageing; Biomedical Research Networking Centre on Mental Health; Institute of Biomedical Research of Lleida; Institute of Health and Biomedical Res earch of Alicante; Carlos III University of Madrid; University of Vigo; Foundation for Biosanitary Research and Innovation in Primary Health Care; Biomedical Research Networking Centre on Epidemiology and Public Health; Research ...
Source: ClinicalTrials.gov - November 2, 2023 Category: Research Source Type: clinical trials

EaveTubes for control of vector-borne diseases in C ôte d’Ivoire: study protocol for a cluster randomized controlled trial
DiscussionFindings will serve as an efficacy trial of ETs and will be submitted to the WHO Vector Control Advisory Group (VCAG) for assessment of public health value. Entomological outcomes will also be measured as proxies of malaria transmission to help develop guidelines for the evaluation of future In2Care ® ETs products.Trial registrationClinicalTrials.gov NCT05736679. Registered on 10 February 2023. (Source: Trials)
Source: Trials - November 2, 2023 Category: Research Source Type: clinical trials

FOVOCIP study: a multicenter randomized trial of fosfomycin versus ciprofloxacin for febrile neutropenia in hematologic patients —efficacy and microbiologic safety
DiscussionThis trial will provide evidence of the efficacy of an alternative drug to ciprofloxacin for febrile neutropenia prevention in high-risk hematological patients. The battery of planned microbiological studies will allow us to evaluate prospectively the microbiological safety of both pharmacological strategies in terms of the selection of MRGNB occurring in each arm. In addition, valuable information on the way in which each drug changes the fecal microbiome of the patients throughout the treatment will be generated.Trial registrationClinical trials NCT05311254, Registered on 5 April 2022,https://clinicaltrials.gov...
Source: Trials - October 27, 2023 Category: Research Source Type: clinical trials

Zinc Supplementation for Young Infants With Clinical Severe Infection in Tanzania
Conditions: Neonatal Infection Interventions: Dietary Supplement: Zinc Supplements; Dietary Supplement: Placebo Supplements Sponsors: Harvard School of Public Health (HSPH); Muhimbili University of Health and Allied Sciences Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - October 26, 2023 Category: Research Source Type: clinical trials

The effect of postoperative intravenous iron in anaemic, older cardiac surgery patients on disability-free survival (AGE ANEMIA study): study protocol for a multi-centre, double-blind, randomized, placebo-controlled trial
This study aims to determine the efficacy of treatment of postoperative iron deficiency anaemia (IDA) with intravenous iron (IVI) on disability 90 days after cardiac surgery in older patients.MethodsThis is a randomized placebo-controlled double-blind multi-centre trial. In total, 310 patients aged ≥ 70 years with moderate IDA on postoperative day 1 (haemoglobin 85–110 g/L and ferritin concentration < 100 μg/L or iron saturation < 20%) after uncomplicated elective cardiac surgery (aortic valve repair or coronary artery bypass graft surgery) will be included. Patients will be randomly allocate...
Source: Trials - October 26, 2023 Category: Research Source Type: clinical trials

CARD for Community Pharmacy Vaccinations
Conditions: Vaccination Reaction; Vaccination Pain; Community Pharmacy Interventions: Behavioral: CARD (Comfort Ask Relax Distract) Sponsors: University of Toronto; Public Health Agency of Canada (PHAC); Wholehealth Pharmacy Partners Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - October 24, 2023 Category: Research Source Type: clinical trials

Community-based type 2 diabetes care by lay village health workers in rural Lesotho: protocol for a cluster-randomized trial within the ComBaCaL cohort study (ComBaCaL T2D TwiC)
DiscussionThe trial was launched on May 13, 2023, and has enrolled 226 participants at the date of submission (October 6, 2023). To our knowledge, the trial is the first to assess task-shifting of T2D care to VHWs at the community level, including the prescription of first-line antidiabetic, lipid-lowering, and antiplatelet medication in sub-Saharan Africa, and will thus provide the missing evidence on the effectiveness of such a T2D care model in this setting. The study is operating within the established Lesotho VHW programme. Similar community health worker programmes which exist across sub-Saharan Africa may benefit fr...
Source: Trials - October 24, 2023 Category: Research Source Type: clinical trials

Transcutaneous electrical vagus nerve stimulation to suppress premature ventricular complexes (TREAT PVC): study protocol for a multi-center, double-blind, randomized controlled trial
DiscussionThe present trial will be the first to evaluate the effect of LLTS on frequent PVCs on patients without SHD. LLTS may serve as a low-cost, minimal-risk, and non-invasive alternative to conventional antiarrhythmic therapy.Trial registrationClinicalTrial.gov NCT04909528. Registered on 17 June 2021. World health organization trial registration data set was shown in Supplementary Table1. (Source: Trials)
Source: Trials - October 23, 2023 Category: Research Source Type: clinical trials

An Adolescent Health and Wellbeing Check-up Programme in Three African Cities (Y-Check)
Conditions: Adolescent Development; Adolescent Behavior; Health-Related Behavior; Health Care Seeking Behavior Interventions: Other: Screening package; Diagnostic Test: Psychosocial and mental health disorder screening; Diagnostic Test: Alcohol, tobacco and substance use screening; Behavioral: Diet and physical activity screening; Diagnostic Test: Underweight and overweight screening; Diagnostic Test: Anemia; Behavioral: Oral health screening; Behavioral: Circumcision screening; Behavioral: Risky behaviours; Diagnostic Test: HIV testing; Diagnostic Test: STI (CT, NG, TV) testing; Behavioral: Immunization screening; Diagnos...
Source: ClinicalTrials.gov - October 19, 2023 Category: Research Source Type: clinical trials

Multicenter Clinical Translational Study of " ICU-NO CRBSI " Based on Improvement Science
Conditions: CRBSI - Catheter Related Bloodstream Infection; Evidence-based Nursing Practice; Central Venous Catheter Related Bloodstream Infection; Central Venous Catheter Associated Bloodstream Infection; Central Line Infection; CLABSI - Central Line Associated Bloodstream Infection; Quality Improvement Interventions: Behavioral: evidence-based intervention Plan for the Prevention of CRBSI in ICU patients Sponsors: Fudan University; Fudan University Evidence-based Nursing Center; Shanghai Zhongshan Hospital; Children ' s Hospital of Fudan University; Shanghai Public Health Clinical Center; Shandong First Medical Universit...
Source: ClinicalTrials.gov - October 17, 2023 Category: Research Source Type: clinical trials

Evaluation of a Multi-country Medical Oxygen Program
Conditions: Hypoxemia; Neonatal Disease; Pneumonia; Sepsis; Morality Interventions: Other: Multi-faceted oxygen systems strengthening interventions (different for each country) Sponsors: Murdoch Childrens Research Institute; Makerere University; University of Health Sciences Lao PDR; University of Health Sciences, Cambodia; Clinton Health Access Initiative, Nigeria; Clinical and Public Health Services at Ministry of Health Rwanda; University of Ibadan Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - October 17, 2023 Category: Research Source Type: clinical trials

A stepped wedge cluster randomized trial to evaluate the effectiveness of a community leader-driven kit-based diabetes self-management education approach in improving diabetes control and care: study protocol for the DElhi Diabetes INTervention Trial (DEDINTT)
This study aims to develop a DSME training kit (EK-DIN), understand barriers to implementation, and evaluate the effectiveness and sustainability of community leader (CL)-based rollout using a stepped wedge cluster randomized trial format.Methods and analysisThe mixed methods study will begin with a qualitative study to evaluate the facilitators and barriers towards CL-based DSME. The in-depth interview notes will be transcribed for thematic analysis. These results will be utilized for a stakeholder ’s workshop to develop the EK-DIN kit, a patient-interfacing app, and an implementation plan. Rollout will be conducted in ...
Source: Trials - October 17, 2023 Category: Research Source Type: clinical trials