SMA-TB: study protocol for the phase 2b randomized double-blind, placebo-controlled trial to estimate the potential efficacy and safety of two repurposed drugs, acetylsalicylic acid and ibuprofen, for use as adjunct therapy added to, and compared with, the standard WHO recommended TB regimen
DiscussionSMA-TB will provide proof of concept of the HDT as a co-adjuvant treatment and identify the suitability of the intervention for different population groups (different epidemiological settings and drug susceptibility) in the reduction of tissue damage and risk of bad outcomes for TB patients. This regimen potentially will be more effective and targeted: organ saving, reducing tissue damage and thereby decreasing the length of treatment and sequelae, increasing cure rates and pathogen clearance and decreasing transmission rates. It will result in better clinical practice, care management and increased well-being of...
Source: Trials - June 28, 2023 Category: Research Source Type: clinical trials

Impact of a Real-time Mentoring Tool on Antibiotic Prescription (medAL-mentor)
Condition:   Primary Health Care for Children Intervention:   Device: MedAL-mentor Sponsors:   Center for Primary Care and Public Health (Unisante), University of Lausanne, Switzerland;   Swiss Tropical & Public Health Institute;   Ifakara Health Institute;   Mbeya Medical Research Centre-National Institute for Medical Research Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - June 13, 2023 Category: Research Source Type: clinical trials

Implementation of the Specific Treatment Of Problems of the Spine Approach in Bangladesh
Condition:   Chronic Low-back Pain Interventions:   Other: Usual physiotherapy care;   Other: Individualized (STOPS) physiotherapy Sponsors:   Mohammad Ali;   Hasna Hena Pain, Physiotherapy and Public Health Research Center (HPRC);   La Trobe University Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - May 30, 2023 Category: Research Source Type: clinical trials