Protective Anesthesiological Management Procedure Imposes Control on Respiratory Comlications
Conditions: Well-Being, Psychological Interventions: Procedure: The procedure of protective lung ventilation Sponsors: Masa Kontic; Prof.Dinko Tonkovi ć, MD, PhD Head of Department of Anesthesiology, Reanimatology and Intensive Care Medicine and Pain Therapy, University Hospital Centre Zagreb; Assist. Prof. Slavica Sović, MD, PhD Department of Medical Statistics, Epidemiology and Medical Informatics, School of Public Health Andrija Štampar; Pro f. Goran Šimić, MD, PhD Professor of Neuroscience and Anatomy, Chair, Department of Neuroscience, Croatian Institute for Brain Research, University of Zagreb; Prof. Anamarija J...
Source: ClinicalTrials.gov - February 28, 2024 Category: Research Source Type: clinical trials

Effects of a chronotype-adapted diet on weight loss, cardiometabolic health, and gut microbiota: study protocol for a randomized controlled trial
This study protocol describes a randomized controlled trial designed to explore the effects of a chronotype-adapted diet, compared with a diet with a conventional calorie distribution, on weight loss, cardiometabolic health, and gut microbiota compo sition.MethodsA total of 150 overweight/obese adults will be recruited for this 4-month parallel-group, randomized, two-arm, open-label, superiority trial with 1:1 allocation ratio. Participants will be randomly assigned to either the intervention group or the control group. The intervention group will receive a low-calorie chronotype-adapted diet with a calorie distribution ad...
Source: Trials - February 28, 2024 Category: Research Source Type: clinical trials

Efficacy of chlorfenapyr-pyrethroid and piperonyl butoxide-pyrethroid long-lasting insecticidal nets (LLINs) compared to pyrethroid-only LLINs for malaria control in C ôte d’Ivoire: a three group, cluster randomised trial
This study conducted in C ôte d’Ivoire will evaluate the efficacy on epidemiological and entomological outcomes of (1) the control arm: MAGNet® LN, which contains the pyrethroid, alpha-cypermethrin, (2) VEERALIN® LN, a net combining the synergist PBO and alpha-cypermethrin, and (3) Interceptor® G2 LN, which incorporate s chlorfenapyr and alpha-cypermethrin, two adulticides with different mechanisms of action. A total of 33 villages with an average of 200 households per village will be identified, mapped, and randomised in a ratio of 1:1:1. Nets will be distributed at a central point following national guidelines w it...
Source: Trials - February 28, 2024 Category: Research Source Type: clinical trials

Effectiveness and cost-effectiveness of a transdiagnostic intervention for alcohol misuse and psychological distress in humanitarian settings: study protocol for a randomised controlled trial in Uganda
DiscussionCHANGE aims to address alcohol misuse and psychological distress with male refugees in a humanitarian setting. If it is proven to be effective, it can help fill an important under-researched gap in humanitarian service delivery.Trial registrationISRCTN ISRCTN10360385. Registered on 30 January 2023. (Source: Trials)
Source: Trials - February 27, 2024 Category: Research Source Type: clinical trials

Patient Empowerment in the Management of Gestational Diabetes Mellitus
Conditions: Diabetes Mellitus in Pregnancy Interventions: Other: Patient Empowerment model Sponsors: Public Health Foundation of Bangladesh Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - February 26, 2024 Category: Research Source Type: clinical trials

Telling Our Daughters Our Story
Conditions: Substance Use; Sexual Behavior Interventions: Behavioral: Nowhi Isdza bit Nadagoldi: Telling Our Daughters Our Story (TODOS); Behavioral: Control condition - 3 Monthly Group Activities in the Community Sponsors: Johns Hopkins Bloomberg School of Public Health; White Mountain Apache Tribe; Native American Research Centers for Health Active, not recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - February 26, 2024 Category: Research Source Type: clinical trials

Implementing an Education- and Health System Task-shifting Approach for Child Mental Health Promotion in Uganda
Conditions: Mental Health Issue; Stigma, Social; Child Development; Child Abuse Interventions: Other: Adapted version of the mhGAP-IG Sponsors: Norwegian Center for Violence and Traumatic Stress Studies; Makerere University; University of Bergen; Norwegian Institute of Public Health; Norwegian University of Science and Technology Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - February 23, 2024 Category: Research Source Type: clinical trials

H. Pylori Screen-and-treat Study in a Population of Young Adults
Conditions: Gastric Cancer; H Pylori Infection; H Pylori Eradication; H-pylori Interventions: Drug: Bismuth-based quadruple therapy; Drug: Levofloxacin-based quadruple therapy; Drug: Standard triple therapy; Drug: Levofloxacin-based triple Sponsors: University of Latvia; Clinical Hospital Center Rijeka; Clinical Hospital Centre Zagreb; Beacon Hospital; Wroclaw Medical University; Iuliu Hatieganu University of Medicine and Pharmacy; National Institute of Public Health, Slovenia Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - February 23, 2024 Category: Research Source Type: clinical trials

Project Phakama: Testing Support Strategies to Empower Young Women on PrEP in South Africa
Conditions: Pre-exposure Prophylaxis; HIV Infections Interventions: Behavioral: Case management; Behavioral: Food vouchers; Behavioral: PrEP support buddy; Behavioral: Community-based PrEP pickup points Sponsors: Johns Hopkins Bloomberg School of Public Health; TB/HIV Care; Unity Health Toronto; National Institute of Mental Health (NIMH) Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - February 23, 2024 Category: Research Source Type: clinical trials

GS-441524 for COVID-19 SAD, FE, and MAD Study in Healthy Subjects
Conditions: COVID-19 Interventions: Drug: GS-441524; Drug: Placebo Sponsors: National Center for Advancing Translational Sciences (NCATS); Leidos Biomedical Research, Inc.; ICON Government and Public Health Solutions, Inc Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - February 23, 2024 Category: Research Source Type: clinical trials

PAIN2.0: study protocol for a multicentre randomised controlled trial to evaluate the efficacy of a 10-week outpatient interdisciplinary multimodal pain therapy to manage recurrent pain for patients with risk factors of developing chronic pain in Germany
DiscussionRecurrent or persistent pain is common in the German population and causes high costs for patients and society. The A-IMPT aims to improve pain and pain-related impairments in pain patients at risk of chronification, thereby reducing the risk of developing chronic pain with its high socioeconomic burden. This new therapy could easily be integrated into existing therapy programs if positively evaluated.Trial registrationThe trial PAIN2.0 has been registered in the German Clinical Trials Register (DRKS) since 21/11/2022 with the IDDRKS00030773. (Source: Trials)
Source: Trials - February 23, 2024 Category: Research Source Type: clinical trials

Evaluation of the Acceptability and Safety of the ShangRing Device for Male Circumcision in Shinyanga, Tanzania
Conditions: Penile Infection; Penile Haematoma; Penile Bleeding; Deformity Interventions: Device: ShangRing Sponsors: IntraHealth International; Ministry of Health, Tanzania; President Office Regional Administration and Local Government, Tanzania; Centers for Disease Control and Prevention; Jhpiego; World Health Organization Completed (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - February 22, 2024 Category: Research Source Type: clinical trials

World Health Organization (WHO) , COVID19 Case Series of Post Covid 19 Rhino Orbito Cerebral Mucormycosis in Egypt
Conditions: Mucormycosis; Rhinocerebral (Etiology); COVID-19 Interventions: Procedure: debridment Sponsors: Nasser Institute For Research and Treatment Completed (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - February 20, 2024 Category: Research Source Type: clinical trials

Hip Fractures in Chile: Implications for Public Health Policy and Healthcare Delivery
Conditions: Hip Fractures Interventions: Procedure: Access to surgery; Other: type of intitution Sponsors: University of Chile; Instituto Sistemas Complejos de Ingenier ía, Universidad de Chile, Santiago, Chile Completed (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - February 20, 2024 Category: Research Source Type: clinical trials

Impact Evaluation of a Targeted mHealth Intervention to Improve Uptake of Postpartum Contraception in Kenya
Conditions: Postpartum Family Planning Interventions: Behavioral: PROMPTS Enhanced Family Planning Counselling Sponsors: Jacaranda Health; Harvard School of Public Health (HSPH); Jhpiego; IPSOS Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - February 20, 2024 Category: Research Source Type: clinical trials