International Medicine & Public Health Clinical Trials This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

The effectiveness of pharmacist-led educational model in adult patients with allergic rhinitis: a single-center randomized control trial protocol (AR-PRISE RCT)
This study protocol outlines a randomized controlled trial (RCT) designed to evaluate the effectiveness of a pharmacist-led educational model (AR-PRISE Model) in managing allergic rhinitis in adult patients compared to standard pharmaceutical care. The AR-PRISE model delivers patient educational material and a pharmaceutical care algorithm.MethodThis is a 6-month, single-center, prospective, randomized, two-arm, and parallel-group controlled trial. The trial recruits patients attending the otorhinolaryngology clinics of a tertiary referral hospital. Participants are randomized into control or intervention groups in a 1:1 r...
Source: Trials - April 25, 2024 Category: Research Source Type: clinical trials

Coordination of COVID-19 platform trials in Europe
AbstractTo ensure optimal coordination of the EU-funded COVID-19 platform trials, a double coordination mechanism was established. It included the Trial Coordination Board (TCB) to promote the dialogue between investigators and relevant public health stakeholders and the Joint Access Advisory Mechanism (JAAM) to streamline access of new intervention arms to the platform trials. Both the TCB and the JAAM emerged as efficient instruments to promote cooperation and optimise the use of resources within EU-funded adaptive platform trials. In addition, an adaptive platform trial toolbox was developed to collect information and l...
Source: Trials - April 25, 2024 Category: Research Source Type: clinical trials

Effectiveness of a Microbiome-directed Food to Promote Programmatic and Sustained Nutritional Recovery Among Children With Uncomplicated Acute Malnutrition
Conditions: Malnutrition, Child Interventions: Dietary Supplement: MDF; Dietary Supplement: RUTF; Dietary Supplement: RUSF Sponsors: Epicentre; Epicentre, Niger; National Nutrition Direction, Niger; Ministry of Public Health and Social Affairs, Niger; Regional Direction of Public Health, Maradi Active, not recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 24, 2024 Category: Research Source Type: clinical trials

Increasing the Coverage of Severe Acute Malnutrition (SAM) Treatment in Ethiopia
Conditions: Acute Malnutrition, Severe; Malnutrition, Child; Wasting Interventions: Behavioral: R-SWITCH integrated intervention package Sponsors: International Food Policy Research Institute; Ethiopian Public Health Association; UNICEF Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 24, 2024 Category: Research Source Type: clinical trials

Unified platforM for a Better integRal Evaluation of MyeLodyspLastic Syndromes in SpAin-Strategy for Unraveling Personalized genoMic Medicine in Public heAlth System (UMBRELLA-SUMMA)
Conditions: Myelodysplastic Syndromes Sponsors: Instituto de Investigaci ón Biomédica de Salamanca; Carlos III Health Institute Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 23, 2024 Category: Research Source Type: clinical trials

Psychiatric Consultation-Liaison Intervention in Primary Care: A Pilot Study
Conditions: Mental Health Issue; Depression/Anxiety; Quality of Life; Psychosomatic Disorders; Patients Lived Experiences; Doctor-Patient Relation; Collaboration Interventions: Other: Intervention arm - Consultation-Liaison (CL) brief psychiatric intervention in primary care settings; Other: Control Arm - Treatment As Usual (TAU) Sponsors: Center for Primary Care and Public Health (Unisante), University of Lausanne, Switzerland; Neuch âtel Psychiatry Centre (CNP); University of Lausanne Hospitals Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 22, 2024 Category: Research Source Type: clinical trials

Haem iron versus ferrous iron salts to treat iron deficiency anaemia in Gambian children: protocol for randomised controlled trial {1}
This study aims to compare da ily supplementation with haem iron versus ferrous sulphate on haemoglobin concentration and serum ferritin concentration after 12 weeks of supplementation.MethodsThis will be a two-arm, randomised controlled trial. Gambian children aged 6 –12 months with anaemia will be recruited within a predefined geographical area and recruited by trained field workers. Eligible participants will be individually randomised using a 1:1 ratio within permuted blocks to daily supplementation for 12 weeks with either 10.0 mg of elemental iron as haem or ferrous sulphate. Safety outcomes such as diarrhoea and i...
Source: Trials - April 19, 2024 Category: Research Source Type: clinical trials

Efficacy and Safety of Emodepside in Adults Infected With Strongyloidiasis Stercoralis
Conditions: Strongyloides Stercoralis Infection; Strongyloidiasis Interventions: Drug: Emodepside Sponsors: Swiss Tropical& Public Health Institute; National Institute of Public Health, Vientiane, Laos Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 18, 2024 Category: Research Source Type: clinical trials

Air Purifiers in Classrooms for Infection Control - a Pilot Study
Conditions: Feasibility; Acceptability Interventions: Device: Ceiling-Mounted Air Purifiers; Device: Portable Air Purifiers; Device: Portable or Ceiling Mounted Air Purifiers Sponsors: Norwegian Institute of Public Health; SINTEF Health Research Active, not recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 18, 2024 Category: Research Source Type: clinical trials

Theta-burst rTMS in schizophrenia to ameliorate negative and cognitive symptoms: study protocol for a double-blind, sham-controlled, randomized clinical trial
DiscussionThis is a double-blind, sham-controlled, randomized medical device study to assess the efficacy and safety of an augmented theta-burst rTMS treatment in schizophrenia. We hypothesize that social cognition and negative symptoms of patients on active therapy will improve significantly compared to patients on sham treatment.Trial registrationThe study protocol is registered at “ClinicalTrials.gov” with the following ID: NCT05100888. All items from the World Health Organization Trial Registration Data Set are registered. Initial release: 10/19/2021. (Source: Trials)
Source: Trials - April 17, 2024 Category: Research Source Type: clinical trials

3D printing vs traditional workflow for the fabrication of mandibular implant overdentures: study protocol for a mixed-methods cross-over RCT
DiscussionThis mixed-methods RCT will explore patient experiences with 3D-printed IMOs, aiming to assess the potential for altering clinical practice and dental public health policies. Our results will inform policies by showing whether 3D printing offers comparable outcomes at lower costs, facilitating greater access to oral care for the elderly.Trial registrationClinicalTrials.gov, NCT06155630, Registered on 04 December 2023.https://classic.clinicaltrials.gov/ct2/show/NCT06155630 (Source: Trials)
Source: Trials - April 16, 2024 Category: Research Source Type: clinical trials

Study protocol for a randomized controlled trial of the Parent –Child Assistance Program: a case management and home visiting program for people using substances during pregnancy
This study protocol describes a randomized controlled trial that aims to examine the effectiveness of the intervention compared to services as usual in affecting primary outcomes related to substance use and family planning. Secondary outcome s will concern connection to recovery support services and family preservation.MethodsUsing an intent-to-treat design, the study will recruit from two metro areas in Oklahoma and enroll 200 birthing individuals who are pregnant or up to 24 months postpartum with at-risk substance use during their current or most recent pregnancy. Participants will be randomly assigned, stratified by...
Source: Trials - April 16, 2024 Category: Research Source Type: clinical trials

Effect of Support for Low-Income Mothers of Preterm Infants
Conditions: Preterm Birth; Low; Birthweight, Extremely (999 Grams or Less) Interventions: Other: Financial Transfers Sponsors: Harvard School of Public Health (HSPH); Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 12, 2024 Category: Research Source Type: clinical trials

The World Health Organization Antenatal CorTicosteroids for Improving Outcomes in preterm Newborns (ACTION-III) Trial: study protocol for a multi-country, multi-centre, double-blind, three-arm, placebo-controlled, individually randomized trial of antenatal corticosteroids for women at high probability of late preterm birth in hospitals in low- resource countries
DiscussionThis trial will evaluate the benefits and possible harms of ACS when used in women likely to have a late preterm birth. It will also evaluate a lower-dose ACS regimen based on literature from pharmacokinetic studies. The results of this trial will provide robust critical evidence on the safe and appropriate use of ACS in the late preterm period internationally.Trial registrationISRCTN11434567. Registered on 7 June 2021. (Source: Trials)
Source: Trials - April 12, 2024 Category: Research Source Type: clinical trials

Therapy and Peer Support for Patients Taking Medication for Opioid Use Disorder
Conditions: Opioid-use Disorder Interventions: Behavioral: Psychosocial treatment Sponsors: Public Health Management Corporation; Boston University; Patient-Centered Outcomes Research Institute; Philadelphia College of Osteopathic Medicine; University of Pennsylvania Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 11, 2024 Category: Research Source Type: clinical trials