International Medicine & Public Health Clinical Trials This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

3D printing vs traditional workflow for the fabrication of mandibular implant overdentures: study protocol for a mixed-methods cross-over RCT
DiscussionThis mixed-methods RCT will explore patient experiences with 3D-printed IMOs, aiming to assess the potential for altering clinical practice and dental public health policies. Our results will inform policies by showing whether 3D printing offers comparable outcomes at lower costs, facilitating greater access to oral care for the elderly.Trial registrationClinicalTrials.gov, NCT06155630, Registered on 04 December 2023.https://classic.clinicaltrials.gov/ct2/show/NCT06155630 (Source: Trials)
Source: Trials - April 16, 2024 Category: Research Source Type: clinical trials

Study protocol for a randomized controlled trial of the Parent –Child Assistance Program: a case management and home visiting program for people using substances during pregnancy
This study protocol describes a randomized controlled trial that aims to examine the effectiveness of the intervention compared to services as usual in affecting primary outcomes related to substance use and family planning. Secondary outcome s will concern connection to recovery support services and family preservation.MethodsUsing an intent-to-treat design, the study will recruit from two metro areas in Oklahoma and enroll 200 birthing individuals who are pregnant or up to 24 months postpartum with at-risk substance use during their current or most recent pregnancy. Participants will be randomly assigned, stratified by...
Source: Trials - April 16, 2024 Category: Research Source Type: clinical trials

Effect of Support for Low-Income Mothers of Preterm Infants
Conditions: Preterm Birth; Low; Birthweight, Extremely (999 Grams or Less) Interventions: Other: Financial Transfers Sponsors: Harvard School of Public Health (HSPH); Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 12, 2024 Category: Research Source Type: clinical trials

The World Health Organization Antenatal CorTicosteroids for Improving Outcomes in preterm Newborns (ACTION-III) Trial: study protocol for a multi-country, multi-centre, double-blind, three-arm, placebo-controlled, individually randomized trial of antenatal corticosteroids for women at high probability of late preterm birth in hospitals in low- resource countries
DiscussionThis trial will evaluate the benefits and possible harms of ACS when used in women likely to have a late preterm birth. It will also evaluate a lower-dose ACS regimen based on literature from pharmacokinetic studies. The results of this trial will provide robust critical evidence on the safe and appropriate use of ACS in the late preterm period internationally.Trial registrationISRCTN11434567. Registered on 7 June 2021. (Source: Trials)
Source: Trials - April 12, 2024 Category: Research Source Type: clinical trials

Therapy and Peer Support for Patients Taking Medication for Opioid Use Disorder
Conditions: Opioid-use Disorder Interventions: Behavioral: Psychosocial treatment Sponsors: Public Health Management Corporation; Boston University; Patient-Centered Outcomes Research Institute; Philadelphia College of Osteopathic Medicine; University of Pennsylvania Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 11, 2024 Category: Research Source Type: clinical trials

Stop Transmission of Gambiense Human African Trypanosomiasis (STROgHAT)
Conditions: Human African Trypanosomiasis Interventions: Drug: Treatment of seropositive individuals (positive serology test, but parasitology not confirmed) Sponsors: Drugs for Neglected Diseases; Institute of Tropical Medicine, Belgium; Institut de Recherche pour le Developpement; Institut National de Recherche Biom édicale. Kinshasa, République Démocratique du Congo; Ministry of Public Health, Democratic Republic of the Congo Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 10, 2024 Category: Research Source Type: clinical trials

Effects of transcutaneous electrical nerve stimulation on pain, function, and descending inhibition in people with non-specific chronic low-back pain: a study protocol for a randomized crossover trial
This study will be a randomized crossover trial. The participants for this study will be recruited from various places, including the University of Hartford, physical therapy clinics, and local businesses in the Hartford area, as well as online websites geared towards clinical trial recruitment. A total of 34 participants will receive all three treatments: active TENS, placebo TENS, and no treatment control. The treatment order will be randomized using a website-based randomization tool. For active TENS, a modulating frequency of 2 –125 Hz will be applied with a variable pulse duration and maximal tolerable intensity fo...
Source: Trials - April 6, 2024 Category: Research Source Type: clinical trials

Chronic Obstructive Pulmonary Disease and Community Health Worker Home-visits
Conditions: COPD Sponsors: VA Puget Sound Health Care System; Public Health - Seattle and King County; University of Washington Completed (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 5, 2024 Category: Research Source Type: clinical trials

Using Behavioural and Cultural Insights to Increase Colorectal Cancer Home-testing in Croatia
Conditions: Colorectal Cancer; Behavior Change Interventions: Behavioral: Standard letter; Behavioral: Behaviorally informed letter; Behavioral: Home testing colorectal cancer kit Sponsors: Veerle Snijders; Croatian Institute of Public Health; Andrija Štampar School of Public Health Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 2, 2024 Category: Research Source Type: clinical trials

Study protocol for a pragmatic randomised controlled trial of comparing enhanced acceptance and commitment therapy plus (+) added to usual aftercare versus usual aftercare only, in patients living with or beyond cancer: SUrvivors ’ Rehabilitation Evaluation after CANcer (SURECAN) trial
DiscussionTo date, there have been no robust trials reporting both clinical and cost-effectiveness of an ACT based intervention for people with low QoL after curative cancer treatment in the UK. We will provide high quality evidence of the effectiveness and cost-effectiveness of adding ACT+ to usual aftercare provided by the NHS. If shown to be effective and cost-effective then commissioners, providers and cancer charities will know how to improve QoL in cancer survivors and their families.Trial registrationISRCTN:ISRCTN67900293. Registered on 09 December 2019.All items from the World Health Organization Trial Registration...
Source: Trials - April 2, 2024 Category: Research Source Type: clinical trials

A Prospective, Multicenter, and Exploratory Study of CMGV in the Treatment of Recurrent Adult AML and MDS-EB-2/Elder AML
Conditions: Recurrent Adult Acute Myeloid Leukemia; Myelodysplastic Syndrome; Adult Acute Myeloid Leukemia Interventions: Drug: CMGV Sponsors: Ruijin Hospital; Huadong Hospital; Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine; Huashan Hospital; Army Medical Center of PLA; Sun Yat-sen University; RenJi Hospital; Shanghai Jiading District Central Hospital; The Second Affiliated Hospital of Dalian Medical University; First Hospital of China Medical University; Dalian Municipal Central Hospital; Shanghai Zhongshan Hospital; Shanghai Pudong Hospital; Shanghai Public Health Clinical Center; Xuhui Cent...
Source: ClinicalTrials.gov - March 26, 2024 Category: Research Source Type: clinical trials

Implementing and evaluating group interpersonal therapy for postnatal depression in Lebanon and Kenya —individually randomised superiority trial
This study seeks to gauge the potency of g-IPT for women with PND in two LMICs.MethodsThis multi-site randomised controlled trial is a continuation of two preceding phases —conceptual mapping and a feasibility study executed in Lebanon and Kenya. Insights gleaned from these phases underpin this comprehensive RCT, which contrasts the efficacy and cost-effectiveness of high-quality standard care (HQ-SC) augmented with g-IPT against HQ-SC in isolation. The trial, chara cterised as an individually randomised superiority assessment, targets women with postnatal depression in Beirut, Lebanon, and Nairobi, Kenya. It aims to det...
Source: Trials - March 26, 2024 Category: Research Source Type: clinical trials

Social Network Overdose Prevention and Education Intervention
Conditions: Drug Overdose Interventions: Behavioral: Network overdose prevention Sponsors: Johns Hopkins Bloomberg School of Public Health; National Institute on Drug Abuse (NIDA) Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 25, 2024 Category: Research Source Type: clinical trials

ImmigrantScreen Telephone Reminder Trial in Colorectal Cancer Screening
Conditions: Participation Rate, Patient Interventions: Behavioral: Reminder telephone call Sponsors: Norwegian Institute of Public Health Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 22, 2024 Category: Research Source Type: clinical trials

Lifestyle intervention in children with obesity and nonalcoholic fatty liver disease (NAFLD): study protocol for a randomized controlled trial in Ningbo city (the SCIENT study)
This study aimed to develop an m-Health-assisted lifestyle intervention program targeting overweight/obese children and assess its effectiveness on indicators of adiposity and NAFLD.MethodsThis is a cluster-randomized controlled trial that conducted in children with overweight/obesity in Ningbo city, Zhejiang Province, China. Students in Grade 3 (8 –10 years old) were recruited from six primary schools, with three be randomized to intervention group and three to usual practice group. The intervention program will last for one academic year and consists of health education, dietary guidance, and physical activity reinfor...
Source: Trials - March 20, 2024 Category: Research Source Type: clinical trials