Vitamin E-enriched medium cross-linked polyethylene in total knee arthroplasty (VIKEP): clinical outcome, oxidation profile, and wear analysis in comparison to standard polyethylene —study protocol for a randomized controlled trial

DiscussionThe comparison between MXE and the standard gliding surface in this study will provide clinical data to confirm preceding biomechanical results in vivo. It is assumed that material-related differences will be identified, i.e., that the new material will be less sensitive to wear and creep. This may become obvious in biomechanical analyses of retrieved implants from revised patients and in radiologic analyses.Trial registrationClinicalTrials.gov, NCT04618016. Registered 27 October 2020,https://clinicaltrials.gov/study/NCT04618016?term=vikep&checkSpell=false&rank=1.All items from the World Health Organization Trial Registration Data Set can be found in Additional file1.
Source: Trials - Category: Research Source Type: clinical trials