Development and validation of a nomogram for predicting 28-day mortality in patients with ischemic stroke
ConclusionsUtilizing a comprehensive array of fourteen readily accessible variables, a prognostic nomogram was meticulously formulated and rigorously validated to provide precise prognostication of short-term mortality within the ischemic stroke cohort. (Source: PLoS One)
Source: PLoS One - April 24, 2024 Category: Biomedical Science Authors: Lingyan Fang Source Type: research

An unexpected case of tetanus in a fully immunized 20-year-old female: a case report
ConclusionThe present case serves as a stark reminder that tetanus may still occur in young, immunized individuals. Patients with a history of immunization may have a better prognosis than those with no immunizations. (Source: International Journal of Emergency Medicine)
Source: International Journal of Emergency Medicine - April 24, 2024 Category: Emergency Medicine Source Type: research

Association between the quantity of stroke care units and the complement of neurosurgical and neurology specialists in Japan: A retrospective study
Initial treatment in a stroke unit (SU) can reduce the mortality of stroke victims, increase the rate of discharge to home, and decrease the amount of time spent in the hospital. The effectiveness of an SU has also been proven in a meta-analysis. Stroke units have been established in various locations in Europe since 1990, and the medical system for managing the acute phase of stroke has improved1, 2. The Japanese Stroke Association recommends in its Stroke Treatment Guidelines 2021 that acute stroke patients should be treated by a multidisciplinary stroke team in an SU that provides intensive care and early rehabilitation...
Source: Journal of Stroke and Cerebrovascular Diseases - April 24, 2024 Category: Neurology Authors: Kentaro Hara, Masato Kanda, Hiroyo Kuwabara, Yoshio Kobayashi, Takahiro Inoue Source Type: research

Post-COVID Trajectory of Pentraxin 3 Plasma Levels Over 6 Months and Their Association with the Risk of Developing Post-Acute Depression and Anxiety
ConclusionsA lower reduction of plasma PTX3 after acute COVID-19 associates with the presence of depression and anxiety, suggesting an involvement of inflammation in post-COVID-19 psychopathology and a potential role of PTX3 as a biomarker. (Source: CNS Drugs)
Source: CNS Drugs - April 24, 2024 Category: Neurology Source Type: research

Carboxyhemoglobin predicts oxygenator performance and imminent oxygenator change in extracorporeal membrane oxygenation
The continuous exposure of blood to a non-biological surface during extracorporeal membrane oxygenation (ECMO) may lead to progressive thrombus formation in the oxygenator, hemolysis and consequently impaired ... (Source: Intensive Care Medicine Experimental)
Source: Intensive Care Medicine Experimental - April 24, 2024 Category: Surgery Authors: Rolf Erlebach, Alix Buhlmann, Rea Andermatt, Benjamin Seeliger, Klaus Stahl, Christian Bode, Reto Schuepbach, Pedro David Wendel-Garcia and Sascha David Tags: Research Articles Source Type: research

Nomenclature issues: non-occlusive mesenteric ischaemia and colon ischaemia
(Source: Intensive Care Medicine)
Source: Intensive Care Medicine - April 24, 2024 Category: Intensive Care Source Type: research

Prone positioning
(Source: Intensive Care Medicine)
Source: Intensive Care Medicine - April 24, 2024 Category: Intensive Care Source Type: research

Norepinephrine dose and concentration reporting: the devil is in the details
(Source: Intensive Care Medicine)
Source: Intensive Care Medicine - April 24, 2024 Category: Intensive Care Source Type: research

Lung ultrasound for diagnosis and management of ARDS
(Source: Intensive Care Medicine)
Source: Intensive Care Medicine - April 24, 2024 Category: Intensive Care Source Type: research

Entangled in stagnant recruitment delusions
(Source: Intensive Care Medicine)
Source: Intensive Care Medicine - April 24, 2024 Category: Intensive Care Source Type: research

Economic analysis of surgical outcome monitoring using control charts: the SHEWHART cluster randomised trial
Conclusions Using control charts paired with indicator feedback to surgical teams was associated with significant reductions in hospital bed-days within 30 days following surgery, and hospital costs reimbursed for this care by the insurer. Trial registration number NCT02569450. (Source: BMJ Quality and Safety)
Source: BMJ Quality and Safety - April 24, 2024 Category: General Medicine Authors: Skinner, S., Pascal, L., Polazzi, S., Chollet, F., Lifante, J.-C., Duclos, A., On behalf of the SHEWHART Trial Group Tags: Open access, Editor's choice Original research Source Type: research

Venous congestion in septic shock quantified with point-of-care ultrasound: a pilot prospective multicentre cohort study
ConclusionsIt is feasible to conduct a definitive observational study exploring the association between venous congestion quantified with POCUS and clinical outcomes in patients with septic shock. We hypothesize that venous congestion may be associated with an increased hazard of receiving RRT. (Source: Canadian Journal of Anesthesia)
Source: Canadian Journal of Anesthesia - April 23, 2024 Category: Anesthesiology Source Type: research

Comparison of effectiveness and safety of molnupiravir versus sotrovimab for COVID ‐19: A systematic review and meta‐analysis
ConclusionThe current findings indicate that sotrovimab may be more effective than molnupiravir in reducing the mortality rate in COVID-19 patients. However, no statistical difference was observed between the two treatments for other effectiveness outcomes. The certainty of evidence for these findings was rated as low or moderate. Further research is required to provide a better comparison of these interventions in treating COVID-19 patients. (Source: Immunity, Inflammation and Disease)
Source: Immunity, Inflammation and Disease - April 23, 2024 Category: Allergy & Immunology Authors: Bahman Amani, Behnam Amani Tags: REVIEW ARTICLE Source Type: research

The influenza landscape and vaccination coverage in older adults during the SARS-Cov-2 pandemic: data from Several European Countries and Israel
Expert Rev Respir Med. 2024 Apr 23. doi: 10.1080/17476348.2024.2340470. Online ahead of print.ABSTRACTINTRODUCTION: The Raise Awareness of Influenza Strategies in Europe (RAISE) group gathered information about the healthcare burden of influenza (hospitalizations, intensive care unit [ICU] admissions, and excess deaths), surveillance systems, and the vaccine coverage rate (VCR) in older adults in 18 European countries and Israel.AREAS COVERED: Published medical literature and official medical documentation on the influenza disease burden in the participating countries were reviewed from 2010/11 until the 2022/23 influenza ...
Source: Expert Review of Respiratory Medicine - April 23, 2024 Category: Respiratory Medicine Authors: George Kassianos Jean-Marie Cohen Rok Civljak Nadav Davidovitch Oana Falup Pecurariu Filipe Froes Andrei Galev Inga Ivaskeviciene Kadri K õivumägi Zuzana Kristufkova Ernest Kuchar Jan Kyncl Helena C Maltezou Milo š Marković Aneta Nitsch-Osuch Raul Ort Source Type: research

Human Airway and Alveolar Organoids from Bronchoalveolar Lavage Fluid
Am J Respir Crit Care Med. 2024 Apr 23. doi: 10.1164/rccm.202310-1831LE. Online ahead of print.NO ABSTRACTPMID:38652140 | DOI:10.1164/rccm.202310-1831LE (Source: Am J Respir Crit Car...)
Source: Am J Respir Crit Car... - April 23, 2024 Category: Intensive Care Authors: Monica Yun Liu Belinda Chen Mehdi Borji Carolina Garcia de Alba Rivas Antonella F M Dost Aaron L Moye Nusrath Movval Abdulla Margherita Paschini Stuart D Rollins Ruobing Wang Lynn M Schnapp Hassan A Khalil Catherine J Wu Nirmal S Sharma Carla F Kim Source Type: research