Internal Iliac Artery Balloon Tamponade in Placenta Accreta: Outcomes From the Largest Tertiary Accreta Referral Centre in British Columbia.
CONCLUSION: Internal iliac artery balloon tamponade decreases blood transfusion requirements among women requiring emergency Caesarean hysterectomy for placenta accreta. Balloon insertion in the operating room may be an important factor in ensuring efficacy of this procedure. Further studies are required to clarify the potential benefits of balloon tamponade in the elective setting. PMID: 30885297 [PubMed - in process] (Source: Journal of Obstetrics and Gynaecology Canada : JOGC)
Source: Journal of Obstetrics and Gynaecology Canada : JOGC - March 21, 2019 Category: OBGYN Tags: J Obstet Gynaecol Can Source Type: research

Medical Adhesive-Related Skin Injuries and Associated Risk Factors in a Pediatric Intensive Care Unit
CONCLUSIONS: Researchers concluded that MARSI is common in the PICU. Skin stripping and skin tear were the most common types, and the face was the most vulnerable site for MARSI, typically attributable to the cloth tape used to affix tracheal intubation. Careful attention should be paid to children with identified risk factors (females, age 2 years or younger, longer hospital stays, edema, infection, or surgery). (Source: Advances in Skin and Wound Care)
Source: Advances in Skin and Wound Care - March 21, 2019 Category: Dermatology Tags: FEATURES: ORIGINAL INVESTIGATIONS Source Type: research

Impact of Education on Hypothermia Delivery during Neonatal Transport
Conclusions: Introduction of a region-wide educational programme may have improved the safety of manual cooling during neonatal transport but it had a negligible impact on its efficacy. The use of servo-controlled cooling during transport should therefore be considered to improve access to the optimal neuroprotective benefits of TH for outborn infants with HIE.Neonatology 2019;116:20 –26 (Source: Neonatology)
Source: Neonatology - March 21, 2019 Category: Perinatology & Neonatology Source Type: research

[Food poisoning outbreak in a kindergarten in the Province of Buenos Aires, Argentina].
Authors: Manfredi EA, Rivas M Abstract On November 27, 2008, a foodborne disease outbreak associated with the consumption of chicken salad occurred in a kindergarten in the District of Hurlingham, Province of Buenos Aires. Thirty-seven children and 10 adults with gastrointestinal symptoms were affected. Five children were hospitalized with signs of dehydration, one of them requiring intensive care. Staphylococcus aureus subsp. aureus was isolated from the mentioned food in 4 out of 5 stool specimens from the patients, and in 3 out of 5 food handlers (nose of food handler #1, hands of food handlers #2 and 3). The is...
Source: Revista Argentina de Microbiologia - March 21, 2019 Category: Microbiology Tags: Rev Argent Microbiol Source Type: research

Persistent hypoxemia after an asthma attack
We report the case of a patient who presented persistent hypoxemia after an adequate treatment for a severe asthma attack requiring intensive care unit admission. The patient underwent a transthoracic microbubbles contrast echocardiography that showed a massive patent foramen ovale. The favorable clinical course and the absence of major signs and symptoms related to patent foramen ovale allowed a conservative approach with a follow-up program. Patent foramen ovale should be suspected in case of persistent hypoxemia after a severe asthma attack had resolved. (Source: Critical Ultrasound Journal)
Source: Critical Ultrasound Journal - March 21, 2019 Category: Radiology Source Type: research

Comparison of the accuracy of three early warning scores with SOFA score for predicting mortality in adult sepsis and septic shock patients admitted to intensive care unit
ConclusionThe SOS presents nearly as good as the SOFA score, to predict mortality among sepsis patients admitted to the ICU. The early warning score is another, alternative tool to use for risk stratification and sepsis screening for ICU sepsis patients. (Source: Heart and Lung: The Journal of Acute and Critical Care)
Source: Heart and Lung: The Journal of Acute and Critical Care - March 20, 2019 Category: Respiratory Medicine Source Type: research

Risk Factors for Central Line-Associated Bloodstream Infection in Critically Ill Neonates
AbstractObjectiveTo identify independent risk factors to develop a central line- associated bloodstream infection (CLABSI) in critically ill neonates with major underlying diseases.MethodsA nested case-control study was conducted in a neonatal intensive care unit (NICU). Patients with a central venous catheter (CVC) were included. Cases were neonates who developed a CLABSI and controls were patients without CLABSI. Variables included: perinatal history, characteristics of the catheter, installation and catheter use, surgical interventions, and hospital stay. Odds ratio (OR) and 95% confidence intervals (CI) were calculated...
Source: Indian Journal of Pediatrics - March 20, 2019 Category: Pediatrics Source Type: research

Risk of Necrotizing Enterocolitis Following Packed Red Blood Cell Transfusion in Very Low Birth Weight Infants
AbstractObjectiveTo evaluate the association between red blood cell (RBC) transfusion leading to necrotizing enterocolitis (NEC) within 48  h, known as transfusion-associated necrotizing enterocolitis (TANEC).MethodsA nested case-control study using historical data was conducted in the neonatal intensive care unit of Songklanagarind Hospital, Thailand. All very low birth weight (VLBW) infants delivered between November 2009 and July 2016 were enrolled. The infants were identified as RBC transfusion received and NEC developed. Logistic regression was used to evaluate risk factors for transfusion and the association bet...
Source: Indian Journal of Pediatrics - March 20, 2019 Category: Pediatrics Source Type: research

Incidence, Risk factors, and Biomarkers Predicting Ischemic or Hemorrhagic Stroke Associated Acute Kidney Injury and Outcome: A Retrospective Study in a General Intensive Care Unit
Conclusions: Among stroke patients in ICU, we identified significant risk factors of stroke-associated AKI. Serum CysC level at ICU admission was an important biomarker for predicting AKI and 28-day mortality.Blood Purif (Source: Blood Purification)
Source: Blood Purification - March 20, 2019 Category: Hematology Source Type: research

Trends in Klebsiella pneumoniae strains isolated from the bloodstream in a teaching hospital in southern Italy.
Authors: Del Prete R, Ronga L, Addati G, Magrone R, Abbasciano A, Decimo M, Mosca A, Miragliotta G Abstract Klebsiella pneumoniae is a common nosocomial pathogen involved in many infectious diseases such as bacteraemia, urinary and respiratory tract infections. It is responsible for the rise in morbidity and mortality rates since most clinical isolates exhibit resistance to several antibiotics. Moreover, the epidemiology of these nosocomial infections is variable across countries and regions. From January 2015 to December 2017 we retrospectively analysed the bloodstream infections caused by K. pneumoniae strains in...
Source: Infezioni in Medicina - March 20, 2019 Category: Infectious Diseases Tags: Infez Med Source Type: research

Triple combination therapy with high-dose ampicillin/sulbactam, high-dose tigecycline and colistin in the treatment of ventilator-associated pneumonia caused by pan-drug resistant Acinetobacter baumannii: a case series study.
Authors: Assimakopoulos SF, Karamouzos V, Lefkaditi A, Sklavou C, Kolonitsiou F, Christofidou M, Fligou F, Gogos C, Marangos M Abstract Acinetobacter baumannii has evolved in recent decades as a major problem in carbapenem-resistant gram-negative nosocomial infections, associated with high mortality rates especially in intensive care units (ICUs). Recent reports highlight the increasing prevalence of resistance to colistin, a last resort therapeutic option for carbapenem-resistant A. baumannii. We retrospectively evaluated the potential efficacy, in terms of clinical and microbiological cure and mortality, of a com...
Source: Infezioni in Medicina - March 20, 2019 Category: Infectious Diseases Tags: Infez Med Source Type: research

Long-term Cognitive and Functional Impairments After Critical Illness.
Abstract As critical illness survivorship increases, patients and health care providers are faced with management of long-term sequelae including cognitive and functional impairment. Longitudinal studies have demonstrated impairments persisting at least 1-5 years after hospitalization for critical illness. Cognitive domains impacted include memory, attention, and processing speed. Functional impairments include physical weakness, reduced endurance, and dependence on others for basic tasks of daily living such as bathing or feeding. In characterizing the trajectory of long-term recovery, multiple risk factors have ...
Source: Anesthesia and Analgesia - March 20, 2019 Category: Anesthesiology Authors: Rengel KF, Hayhurst CJ, Pandharipande PP, Hughes CG Tags: Anesth Analg Source Type: research

Management of the child's airway under anaesthesia: The French guidelines
ConclusionsSubstantial agreement exists among experts regarding many strong recommendations for paediatric airway management. (Source: Anaesthesia, Critical Care and Pain Medicine)
Source: Anaesthesia, Critical Care and Pain Medicine - March 20, 2019 Category: Anesthesiology Source Type: research

Self-assessment
Publication date: Available online 20 March 2019Source: Anaesthesia & Intensive Care MedicineAuthor(s): Viyayanand Nadella (Source: Anaesthesia and intensive care medicine)
Source: Anaesthesia and intensive care medicine - March 20, 2019 Category: Anesthesiology Source Type: research

Anaesthesia for vascular surgery on the extremities
Publication date: Available online 20 March 2019Source: Anaesthesia & Intensive Care MedicineAuthor(s): Richard J. TelfordAbstractPeripheral arterial surgery is challenging, operations are frequently long and associated with insidious blood loss. Because of the high incidence of comorbidities these patients are a high-risk group with a high incidence of morbidity and mortality. They key to successful outcome is meticulous attention to detail by all those professions involved in their care. (Source: Anaesthesia and intensive care medicine)
Source: Anaesthesia and intensive care medicine - March 20, 2019 Category: Anesthesiology Source Type: research

Preoperative assessment of patients for major vascular surgery
Publication date: Available online 19 March 2019Source: Anaesthesia & Intensive Care MedicineAuthor(s): James W. Durrand, Gerard R. DanjouxAbstractEffective preoperative evaluation of patients prior to major vascular surgery remains a significant multidisciplinary challenge. Focussed preoperative evaluation targeted to organ systems can mitigate the combined effects of inherently high-risk surgical procedures undertaken in a patient population with well-recognized comorbidity. Careful history and examination, supported by appropriate investigations and specialist input, remains the cornerstone of this process, with ris...
Source: Anaesthesia and intensive care medicine - March 20, 2019 Category: Anesthesiology Source Type: research

Applied cardiovascular physiology
Publication date: Available online 19 March 2019Source: Anaesthesia & Intensive Care MedicineAuthor(s): Carla Gould, Jon HopperAbstractMaintaining an equilibrium between oxygen supply and demand is a principal function of the cardiovascular system. In times of altered metabolic demand mechanisms exist to maintain the balance between supply and demand. Exercise, haemorrhage and pregnancy all lead to changes in oxygen demand and subsequently modification of cardiac output. During isotonic exercise, metabolic demands of muscle are greatly increased. Sympathetic stimulation and inhibition of the parasympathetic system lead...
Source: Anaesthesia and intensive care medicine - March 20, 2019 Category: Anesthesiology Source Type: research

Anaesthesia for open abdominal aortic surgery
Publication date: Available online 19 March 2019Source: Anaesthesia & Intensive Care MedicineAuthor(s): Alastair Duncan, Adam PichelAbstractThe prevalence of abdominal aortic aneurysm (AAA) and the number of patients undergoing aneurysm repair is increasing. The UK has worked tirelessly to reduce its operative mortality rates for elective open AAA repair with the introduction of a quality improvement programme. Reducing death from ruptured aortic aneurysm has been the focus of the national screening programme. Despite the increased prevalence of disease and intervention, the popularity of open repair has diminished sin...
Source: Anaesthesia and intensive care medicine - March 20, 2019 Category: Anesthesiology Source Type: research

Cardiovascular Insufficiency, Abdominal Sepsis, and Patients' Age Are Associated with Decreased Paraoxonase-1 (PON1) Activity in Critically Ill Patients with Multiple Organ Dysfunction Syndrome (MODS).
Authors: Bednarz-Misa I, Mierzchala-Pasierb M, Lesnik P, Placzkowska S, Kedzior K, Gamian A, Krzystek-Korpacka M Abstract Oxidative stress and uncontrolled inflammation are hallmarks of sepsis, leading to organ failure and death. As demonstrated in animal studies, oxidative stress can be alleviated by antioxidant therapies. Paraoxonase-1 (PON1) is a serum-based antioxidant, anti-inflammatory agent, detoxifier, and quorum-sensing factor found to be a prognostic marker in sepsis. However, its associations with multiple organ dysfunction syndrome (MODS), a complication of sepsis and the leading cause of death in the s...
Source: Disease Markers - March 20, 2019 Category: Laboratory Medicine Tags: Dis Markers Source Type: research

The Dependence of Machine Learning on Electronic Medical Record Quality.
Authors: Ho LV, Ledbetter D, Aczon M, Wetzel R Abstract There is growing interest in applying machine learning methods to Electronic Medical Records (EMR). Across different institutions, however, EMR quality can vary widely. This work investigated the impact of this disparity on the performance of three advanced machine learning algorithms: logistic regression, multilayer perceptron, and recurrent neural network. The EMR disparity was emulated using different permutations of the EMR collected at Children's Hospital Los Angeles (CHLA) Pediatric Intensive Care Unit (PICU) and Cardiothoracic Intensive Care Unit (CTICU...
Source: AMIA Annual Symposium Proceedings - March 20, 2019 Category: Bioinformatics Tags: AMIA Annu Symp Proc Source Type: research

Erratum: Correction of Error in Result: Comparison of Follow-up Courses after Discharge from Neonatal Intensive Care Unit between Very Low Birth Weight Infants with and without Home Oxygen.
Authors: Kim JS, Shim JW, Lee JH, Chang YS, Committee on Data Collection and Statistical Analysis, the Korean Society of Neonatology Abstract [This corrects the article on p. 1295 in vol. 32, PMID: 28665066.]. PMID: 30886554 [PubMed - in process] (Source: Journal of Korean Medical Science)
Source: Journal of Korean Medical Science - March 20, 2019 Category: Biomedical Science Tags: J Korean Med Sci Source Type: research

Early Mobilization of Patients With External Ventricular Drains: Does Therapist Experience Matter?
Conclusion: This analysis suggests that patients with EVDs in the neuro-intensive care unit can be safely and efficiently mobilized by physical therapists and occupational therapists of varying levels of clinical experience. Early mobilization of patients with EVDs may demand fewer staff resources than perceived by clinicians. (Source: The Journal of Acute Care Physical Therapy)
Source: The Journal of Acute Care Physical Therapy - March 20, 2019 Category: Physiotherapy Tags: Original Studies Source Type: research

Interrater Reliability of the Functional Status Score for the Intensive Care Unit: Erratum
No abstract available (Source: The Journal of Acute Care Physical Therapy)
Source: The Journal of Acute Care Physical Therapy - March 20, 2019 Category: Physiotherapy Tags: Erratum Source Type: research

Trends in Chlorhexidine Use in US Neonatal Intensive Care Units: Results From a Follow-Up National Survey
Brief ReportJulia Johnson, Rebecca Bracken, Pranita D. Tamma, Susan W. Aucott, Cynthia Bearer, Aaron M. Milstone,Infection Control& Hospital Epidemiology,Volume 37 Issue 09, pp 1116-1118Abstract (Source: Infection Control and Hospital Epidemiology)
Source: Infection Control and Hospital Epidemiology - March 20, 2019 Category: Epidemiology Source Type: research

The Need to Better Define the Who, What, and Where of REBOA
In this issue ofJAMA Surgery, Joseph et al examine the outcomes in trauma patients after resuscitative endovascular balloon occlusion of the aorta (REBOA) placement using 2 years of the American College of Surgeons Trauma Quality Improvement Program (ACS-TQIP) data set. The results demonstrate that patients in a propensity-matched cohort (140 patients in the REBOA group and 280 patients in the no-REBOA group) who underwent REBOA had a higher 24-hour mortality rate, acute kidney injury rate, and amputation rate. Yet, there was no difference in mortality in the emergency department or mortality after 24 hours in the hospital...
Source: JAMA Surgery - March 20, 2019 Category: Sports Medicine Source Type: research

Surface colonization and subsequent development of infections with multi drug resistant organisms in a neonatal intensive care unit
This study analyzes colonization of the neonates in a NICU and incidence of these colonized infants developing infections due to the colonizers. (Source: Annals of Clinical Microbiology and Antimicrobials)
Source: Annals of Clinical Microbiology and Antimicrobials - March 20, 2019 Category: Microbiology Authors: Mary Dias and Juveyriya Saleem Tags: Research Source Type: research

Gut integrity in critical illness
ConclusionThe gut plays a complex role in both health and critical illness. Here, we review gut integrity in both health and illness and highlight potential strategies for targeting the intestine for therapeutic gain in the intensive care unit. (Source: Journal of Intensive Care)
Source: Journal of Intensive Care - March 20, 2019 Category: Intensive Care Source Type: research

Effects of norepinephrine and vasopressin discontinuation order in the recovery phase of septic shock: a systematic review and individual patient data meta ‐analysis
ConclusionsDiscontinuation of norepinephrine prior to vasopressin during the recovery phase of septic shock resulted in less clinically significant hypotension but no difference in mortality or lengths of stay. Larger, prospective studies evaluating the impact of relative vasopressin deficiency and norepinephrine and vasopressin discontinuation order and timing on patient ‐centered outcomes are needed.This article is protected by copyright. All rights reserved. (Source: Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy)
Source: Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy - March 20, 2019 Category: Drugs & Pharmacology Authors: Drayton A Hammond, Gretchen L Sacha, Brittany D Bissell, Nadine Musallam, Diana Altshuler, Alexander H Flannery, Simon W Lam, Seth R Bauer Tags: Original Research Article Source Type: research

Non-invasive ventilation versus high-flow nasal cannula oxygen therapy with apnoeic oxygenation for preoxygenation before intubation of patients with acute hypoxaemic respiratory failure: a randomised, multicentre, open-label trial
Publication date: Available online 18 March 2019Source: The Lancet Respiratory MedicineAuthor(s): Jean-Pierre Frat, Jean-Damien Ricard, Jean-Pierre Quenot, Nicolas Pichon, Alexandre Demoule, Jean-Marie Forel, Jean-Paul Mira, Rémi Coudroy, Guillaume Berquier, Benoit Voisin, Gwenhaël Colin, Bertrand Pons, Pierre Eric Danin, Jérome Devaquet, Gwenael Prat, Raphaël Clere-Jehl, Franck Petitpas, Emmanuel Vivier, Keyvan Razazi, Mai-Anh NaySummaryBackgroundNon-invasive ventilation has never been compared with high-flow oxygen to determine whether it reduces the risk of severe hypoxaemia during intubation. We...
Source: The Lancet Respiratory Medicine - March 19, 2019 Category: Respiratory Medicine Source Type: research

Circulating heparan sulfate fragments mediate septic cognitive dysfunction
Septic patients frequently develop cognitive impairment that persists beyond hospital discharge. The impact of sepsis on electrophysiological and molecular determinants of learning is underexplored. We observed that mice that survived sepsis or endotoxemia experienced loss of hippocampal long-term potentiation (LTP), a brain-derived neurotrophic factor–mediated (BDNF-mediated) process responsible for spatial memory formation. Memory impairment occurred despite preserved hippocampal BDNF content and could be reversed by stimulation of BDNF signaling, suggesting the presence of a local BDNF inhibitor. Sepsis is associa...
Source: Journal of Clinical Investigation - March 19, 2019 Category: Biomedical Science Authors: Joseph A. Hippensteel, Brian J. Anderson, James E. Orfila, Sarah A. McMurtry, Robert M. Dietz, Guowei Su, Joshay A. Ford, Kaori Oshima, Yimu Yang, Fuming Zhang, Xiaorui Han, Yanlei Yu, Jian Liu, Robert J. Linhardt, Nuala J. Meyer, Paco S. Herson, Eric P. Source Type: research

Profile of hospitalizations in Pediatric Intensive Care Units of the Brazilian Unified Health System in the state of Pernambuco, Brazil
Resumo No Brasil, a distribui ção das unidades de terapia intensiva pediátrica (UTIP), causas de admissão, custos despendidos e forma como se presta a assistência ainda são pouco conhecidos. Com o objetivo de descrever o perfil das internações por faixa etária em UTIP do SUS de Pernambuco, em 2010, realizou-se um estudo transversal, com o universo das 1.915 internações nas seis UTIP do estado, captadas no Sistema de Informação Hospitalar. As variáveis foram comparadas por faixa etária. Predominaram internaçõ...
Source: Ciencia e Saude Coletiva - March 19, 2019 Category: Occupational Health Source Type: research

39th International Symposium on Intensive Care and Emergency Medicine
(Source: Critical Care)
Source: Critical Care - March 19, 2019 Category: Intensive Care Tags: Meeting abstracts Source Type: research

Limited genetic variability of Cytauxzoon felis apical membrane antigen-1 (ama1) from domestic cats and bobcats
Cytauxzoon felis is a tick-transmitted apicomplexan that causes cytauxzoonosis in domestic cats (Felis catus). Even with intensive care, the mortality rate of acute cytauxzoonosis approaches 40% in domestic cats,... (Source: Parasites and Vectors)
Source: Parasites and Vectors - March 19, 2019 Category: Microbiology Authors: Jaime L. Tarigo, Lisa S. Kelly, Holly M. Brown and David S. Peterson Tags: Research Source Type: research

Randomized controlled trial protocol to improve multisensory neural processing, language and motor outcomes in preterm infants
Premature infants are at risk for abnormal sensory development due to brain immaturity at birth and atypical early sensory experiences in the Neonatal Intensive Care Unit. This altered sensory development can ... (Source: BMC Pediatrics)
Source: BMC Pediatrics - March 19, 2019 Category: Pediatrics Authors: Mary Lauren Neel, Paul Yoder, Pawel J. Matusz, Micah M. Murray, Ashley Miller, Stephanie Burkhardt, Lelia Emery, Kaleigh Hague, Caitlin Pennington, Jessica Purnell, Megan Lightfoot and Nathalie L. Maitre Tags: Study protocol Source Type: research

Oblique-axis view should be the preferred view for ultrasound-guided internal jugular vein cannulation in intensive care unit
Swati Singh, Raja AvinashSaudi Journal of Anaesthesia 2019 13(2):159-160 (Source: Saudi Journal of Anaesthesia)
Source: Saudi Journal of Anaesthesia - March 19, 2019 Category: Anesthesiology Authors: Swati Singh Raja Avinash Source Type: research

Green plasma and a blocked CRRT circuit due to drug-induced hyperlipidemia
(Source: Intensive Care Medicine)
Source: Intensive Care Medicine - March 19, 2019 Category: Intensive Care Source Type: research

Nasal high-flow preoxygenation for endotracheal intubation in the critically ill patient? Pro
(Source: Intensive Care Medicine)
Source: Intensive Care Medicine - March 19, 2019 Category: Intensive Care Source Type: research

Nasal high-flow preoxygenation for endotracheal intubation in the critically ill patient? Maybe
(Source: Intensive Care Medicine)
Source: Intensive Care Medicine - March 19, 2019 Category: Intensive Care Source Type: research

Cardiovascular clusters in septic shock combining clinical and echocardiographic parameters: a post hoc analysis
AbstractPurposeMechanisms of circulatory failure are complex and frequently intricate in septic shock. Better characterization could help to optimize hemodynamic support.MethodsTwo published prospective databases from 12 different ICUs including echocardiographic monitoring performed by a transesophageal route at the initial phase of septic shock were merged for post hoc analysis. Hierarchical clustering in a principal components approach was used to define cardiovascular phenotypes using clinical and echocardiographic parameters. Missing data were imputed.FindingsA total of 360 patients (median age 64 [55; 74]) were inclu...
Source: Intensive Care Medicine - March 19, 2019 Category: Intensive Care Source Type: research

Obesity in the critically ill: a narrative review
AbstractThe World Health Organization defines overweight and obesity as the condition where excess or abnormal fat accumulation increases risks to health. The prevalence of obesity is increasing worldwide and is around 20% in ICU patients. Adipose tissue is highly metabolically active, and especially visceral adipose tissue has a deleterious adipocyte secretory profile resulting in insulin resistance and a chronic low-grade inflammatory and procoagulant state. Obesity is strongly linked with chronic diseases such as type 2 diabetes, hypertension, cardiovascular diseases, dyslipidemia, non-alcoholic fatty liver disease, chr...
Source: Intensive Care Medicine - March 19, 2019 Category: Intensive Care Source Type: research

High flow nasal cannula compared with conventional oxygen therapy for acute hypoxemic respiratory failure: a systematic review and meta-analysis
ConclusionIn patients with acute hypoxemic respiratory failure, HFNC may decrease the need for tracheal intubation without impacting mortality. (Source: Intensive Care Medicine)
Source: Intensive Care Medicine - March 19, 2019 Category: Intensive Care Source Type: research

Deformable multimodal registration for navigation in beating-heart cardiac surgery
Conclusion:The proposed algorithm registered 3D CT with dynamic 2D intraoperative imaging. The algorithm aligned the images in both space and time, needing neither dynamic CT imaging nor intraoperative electrocardiograms. The accuracy was sufficient for navigation in thoracoscopically guided beating-heart surgery. (Source: International Journal of Computer Assisted Radiology and Surgery)
Source: International Journal of Computer Assisted Radiology and Surgery - March 19, 2019 Category: Intensive Care Source Type: research

Toward an automatic preoperative pipeline for image-guided temporal bone surgery
ConclusionAutomatic segmentation and trajectory planning for various clinical procedures at the temporal bone are feasible. The proposed automatic pipeline leads to an efficient and unbiased workflow for preoperative planning. (Source: International Journal of Computer Assisted Radiology and Surgery)
Source: International Journal of Computer Assisted Radiology and Surgery - March 19, 2019 Category: Intensive Care Source Type: research

Semantic segmentation and detection of mediastinal lymph nodes and anatomical structures in CT data for lung cancer staging
ConclusionFusing 2D networks ’ results increases pixel-wise segmentation results while enabling good instance detection. Better leveraging of the 3D information and station mapping for the detected lymph nodes are the next steps. (Source: International Journal of Computer Assisted Radiology and Surgery)
Source: International Journal of Computer Assisted Radiology and Surgery - March 19, 2019 Category: Intensive Care Source Type: research

Comparison of the accuracy of three early warning scores with SOFA score for predicting mortality in adult sepsis and septic shock patients admitted to intensive care unit
The purpose of this study was to compare the accuracy of the Modified Early Warning Score (MEWS), National Early Warning Score (NEWS) and Search Out Severity (SOS), with the quick Sequential Organ Failure Assessment (qSOFA) and SOFA scores, to predict outcomes in sepsis patients. (Source: Heart and Lung)
Source: Heart and Lung - March 19, 2019 Category: Intensive Care Authors: Bodin Khwannimit, Rungsun Bhurayanontachai, Veerapong Vattanavanit Source Type: research

A Case of Massive Hepatic Infarction in a Patient with HELLP Syndrome
Conclusion Hepatic infarction is an extraordinarily rare complication of pre-eclampsia. Early recognition and prompt multidisciplinary management are vital to prevent catastrophic bleeding, hepatic failure, and death. [...] Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.Article in Thieme eJournals: Table of contents  |  Abstract  |  open access Full text (Source: American Journal of Perinatology Reports)
Source: American Journal of Perinatology Reports - March 19, 2019 Category: Perinatology & Neonatology Authors: Morgan, Jessica Della Torre, Micaela Whelan, Anna R. Rodriguez, Sophia M. DiGiovanni, Laura M. Tags: Case Report Source Type: research

Impact of Education on Hypothermia Delivery during Neonatal Transport.
CONCLUSIONS: Introduction of a region-wide educational programme may have improved the safety of manual cooling during neonatal transport but it had a negligible impact on its efficacy. The use of servo-controlled cooling during transport should therefore be considered to improve access to the optimal neuroprotective benefits of TH for outborn infants with HIE. PMID: 30889592 [PubMed - as supplied by publisher] (Source: Neonatology)
Source: Neonatology - March 19, 2019 Category: Perinatology & Neonatology Authors: Saito-Benz M, Cody S, Dineen F, Mladenovic J, Berry MJ Tags: Neonatology Source Type: research

Optic Nerve Sheath Diameter for Preterm Infants: A Pilot Study.
CONCLUSION: In preterm infants, ONSD strongly correlates with corrected gestational age. These data should be validated with other imaging modalities before abnormal ranges can be considered. PMID: 30889584 [PubMed - as supplied by publisher] (Source: Neonatology)
Source: Neonatology - March 19, 2019 Category: Perinatology & Neonatology Authors: Ardell S, Daspal S, Holt T, Hansen G Tags: Neonatology Source Type: research

New SPE-LC-MS/MS method for the simultaneous determination in urine of 22 metabolites of DEHP and alternative plasticizers from PVC medical devices.
Abstract DiEthylHexylPhthalate (DEHP) can leach out of plasticized PVC medical devices (MD) and may enter into contact with patients. This phthalate is known for its reprotoxic and endocrine disrupting effects. Its use in medical devices (MD) has been restricted and alternative plasticizers have been developed. Nevertheless, no published clinical studies exist concerning patient exposure to these alternative plasticizers during medical care. This is particularly worrisome when high-risk populations, such as newborns, are exposed to these new plasticizers in intensive care units. Our study aimed to develop a novel ...
Source: Talanta - March 18, 2019 Category: Chemistry Authors: Pinguet J, Kerckhove N, Eljezi T, Lambert C, Moreau E, Bernard L, Boeuf B, Decaudin B, Genay S, Masse M, Storme L, Sautou V, Richard D, ARMED Study Group Tags: Talanta Source Type: research

Effect of Hyperoxygenation During Surgery on Surgical Site Infection in Colorectal Surgery.
This study was performed to evaluate the effect of hyperoxygenation during colorectal surgery on the incidence of wound infection. METHODS: This study was a prospective double-blind case-control study. The main aim of the study was to evaluate the effect of hyperoxygenation during colorectal surgery on the incidence of SSI. Also, secondary outcomes, such as atelectasis, pneumonia, respiratory failure, length of hospital stay, and required hospitalization in the intensive care unit were evaluated. RESULTS: SSI was recorded in 2 patients (2 of 40, 5%) in the hyperoxygenation group (FiO2 80%) and 6 patients (6 of 40, ...
Source: Annals of Coloproctology - March 18, 2019 Category: Gastroenterology Tags: Ann Coloproctol Source Type: research