Intrauterine fetal resuscitation
Publication date: Available online 15 June 2019Source: Anaesthesia & Intensive Care MedicineAuthor(s): Hannah Kither, Suna MonaghanAbstractThe delivery of oxygen to the fetus is dependent on adequate maternal blood oxygen concentration, uterine blood supply, placental transfer and fetal gas transport. Any disturbance in these factors, singly or in combination, can result in progressive fetal hypoxia and acidosis. The term fetal distress is non-specific but is usually applied to certain characteristic features on electronic fetal monitoring, confirmed if possible by fetal blood sampling. The aim of intrauterine fetal re...
Source: Anaesthesia and intensive care medicine - June 16, 2019 Category: Anesthesiology Source Type: research

Pre-eclampsia and the anaesthetist
Publication date: Available online 15 June 2019Source: Anaesthesia & Intensive Care MedicineAuthor(s): Yogini Kalamkar, Kailash BhatiaAbstractPre-eclampsia is a multisystem disorder of pregnancy that forms an integral part of the spectrum known as hypertensive diseases of pregnancy, occurring after 20 weeks of gestation. Intracerebral haemorrhage, pulmonary, liver and renal dysfunction are recognized complications of pre-eclampsia that contribute to maternal morbidity and mortality. Measurement of specific maternal angiogenic factors such as placental growth factor (PlGF) and soluble FMS-like tyrosine kinase-1 (sFlt-1)...
Source: Anaesthesia and intensive care medicine - June 16, 2019 Category: Anesthesiology Source Type: research

Antenatal anaesthetic assessment of high risk obstetric patients
Publication date: Available online 14 June 2019Source: Anaesthesia & Intensive Care MedicineAuthor(s): Nosakhare A. Uwubamwen, Dipali VermaAbstractEarly identification and anaesthetic assessment of high-risk patients in pregnancy is important and best delivered through a formal assessment clinic. It provides the opportunity to provide information, agree management plans, and carry out necessary investigations and referrals to other specialists prior to labour and delivery. Clear referral criteria and lines of communication are necessary for an effective service. (Source: Anaesthesia and intensive care medicine)
Source: Anaesthesia and intensive care medicine - June 16, 2019 Category: Anesthesiology Source Type: research

Neonatal outcomes in Syrian and other refugees treated in a tertiary hospital in Turkey
Authors: Çelik İH, Arslan Z, Ulubaş Işık D, Tapısız ÖL, Mollamahmutoğlu L, Baş AY, Demirel N Abstract Background/aim: Turkey accepts refugees from many countries, principally Syria. More than 2.7 million refugees live in Turkey. We evaluated the neonatal outcomes of refugees. Materials and methods: We retrospectively reviewed the clinical and demographic characteristics of refugee infants born in our hospital between August 2013 and September 2016. Results: Refugees (718 Syrian, 136 Iraqi, 32 Afghani, and 21 of other nationalities) accounted for 907 of 49,413 births. The mean refugee mat...
Source: Turkish Journal of Medical Sciences - June 15, 2019 Category: General Medicine Tags: Turk J Med Sci Source Type: research

Viral prevalence, clinical profiles and comparison of severity scores for predicting the mortality of adults with severe acute respiratory infections
Conclusion: SOFA and APACHE II were more accurate than SIRS in predicting the 28-day mortality among adults with SARI. There was no significant difference among these scores in terms of other multivariate comparisons. PMID: 31195770 [PubMed - as supplied by publisher] (Source: Turkish Journal of Medical Sciences)
Source: Turkish Journal of Medical Sciences - June 15, 2019 Category: General Medicine Tags: Turk J Med Sci Source Type: research

This week's questions
Publication date: 15 June 2019Source: New Scientist, Volume 242, Issue 3234Author(s): A few years ago, I was bitten on the hand by a red-bellied black snake. After a night in intensive care (during which I was not given antivenom), I soon recovered, with one exception: the complete loss of my sense of smell. How can a bite on the hand do this and could it affect other senses? (Source: New Scientist)
Source: New Scientist - June 15, 2019 Category: Science Source Type: research

Geriatric Assessment, Not ASA Physical Status, Is Associated With 6-Month Postoperative Survival in Patients With Cancer Aged ≥75 Years.
Geriatric Assessment, Not ASA Physical Status, Is Associated With 6-Month Postoperative Survival in Patients With Cancer Aged ≥75 Years. J Natl Compr Canc Netw. 2019 Jun 01;17(6):687-694 Authors: Shahrokni A, Vishnevsky BM, Jang B, Sarraf S, Alexander K, Kim SJ, Downey R, Afonso A, Korc-Grodzicki B Abstract BACKGROUND: The American Society of Anesthesiologists physical status (ASA PS) classification system is the most common method of assessing preoperative functional status. Comprehensive geriatric assessment (CGA) has been proposed as a supplementary tool for preoperative assessment of older adult...
Source: Journal of the National Comprehensive Cancer Network : JNCCN - June 15, 2019 Category: Cancer & Oncology Tags: J Natl Compr Canc Netw Source Type: research

Fresh Red Cells for Transfusion in Critically Ill Adults: An Economic Evaluation of the Standard Issue Transfusion Versus Fresher Red-Cell Use in Intensive Care (TRANSFUSE) Clinical Trial
Conclusions: Without considering the additional supply cost of implementing a freshest available RBC strategy for critical care patients, there is no evidence to suggest that the policy improves quality-of-life or reduces other costs compared with standard transfusion practice. (Source: Critical Care Medicine)
Source: Critical Care Medicine - June 15, 2019 Category: Emergency Medicine Tags: Online Clinical Investigations Source Type: research

Untangling Infusion Confusion: A Comparative Evaluation of Interventions in a Simulated Intensive Care Setting
Objectives: Assess interventions’ impact on preventing IV infusion identification and disconnection mix-ups. Design: Experimental study with repeated measures design. Setting: High fidelity simulated adult ICU. Subjects: Forty critical care nurses. Interventions: Participants had to correctly identify infusions and disconnect an infusion in four different conditions: baseline (current practice); line labels/organizers; smart pump; and light-linking system. Measurements and Main Results: Participants identified infusions with significantly fewer errors when using line labels/organizers (0; 0%) than in...
Source: Critical Care Medicine - June 15, 2019 Category: Emergency Medicine Tags: Online Brief Report Source Type: research

Association Between Mean Arterial Pressure and Acute Kidney Injury and a Composite of Myocardial Injury and Mortality in Postoperative Critically Ill Patients: A Retrospective Cohort Analysis
Objectives: Hypotension thresholds that provoke renal injury, myocardial injury, and mortality in critical care patients remain unknown. We primarily sought to determine the relationship between hypotension and a composite of myocardial injury (troponin T ≥ 0.03 ng/mL without nonischemic cause) and death up to 7 postoperative days. Secondarily, we considered acute kidney injury (creatinine concentration ≥ 0.3 mg/dL or 1.5 times baseline). Design: Retrospective cohort. Setting: Surgical ICU at an academic medical center. Patients: Two-thousand eight-hundred thirty-three postoperative patients ...
Source: Critical Care Medicine - June 15, 2019 Category: Emergency Medicine Tags: Clinical Investigations Source Type: research

Perceived differences between intensivists and infectious diseases consultants facing antimicrobial resistance: a global cross-sectional survey
AbstractTo identify differences in perception on multi-drug-resistant (MDR) organisms and their management at intensive care units (ICU). A cross-sectional survey was conducted. A proposal addressing a pathogen priority list (PPL) for ICU, arising from the TOTEM study, was compared with a sample of global experts in infections in critically ill patients. The survey was responded by 129 experts. Globally, ESBL Enterobacteriaceae, followed by carbapenem-resistantAcinetobacter baumannii and carbapenem-resistant Klebsiellapneumoniae, were the main concerns. Some differences in opinion were identified between 63 (49%) ICU physi...
Source: European Journal of Clinical Microbiology and Infectious Diseases - June 15, 2019 Category: Microbiology Source Type: research

Implicit domain adaptation with conditional generative adversarial networks for depth prediction in endoscopy
ConclusionsTraining the discriminator and generator of the model on real images, we show that our model performs implicit domain adaptation, which is a key step towards bridging the gap between synthetic and real data. Importantly, we demonstrate the feasibility of training a single model to predict depth from both synthetic and real images without the need for explicit, unsupervised transformer networks mapping between the domains of synthetic and real data. (Source: International Journal of Computer Assisted Radiology and Surgery)
Source: International Journal of Computer Assisted Radiology and Surgery - June 15, 2019 Category: Intensive Care Source Type: research

Post-traumatic stress in the intensive care unit
Publication date: Available online 13 June 2019Source: The Lancet Respiratory MedicineAuthor(s): Talha Khan Burki (Source: The Lancet Respiratory Medicine)
Source: The Lancet Respiratory Medicine - June 15, 2019 Category: Respiratory Medicine Source Type: research

Comparison of Venous Thromboembolism Prophylactic Measures Post Coronary Artery Bypass Graft Surgery
ConclusionsWe report no statistical difference in the rates of VTE or bleeding between chemical agents, but our results suggest enoxaparin may be a preferred agent over UFH. (Source: American Journal of Cardiovascular Drugs)
Source: American Journal of Cardiovascular Drugs - June 15, 2019 Category: Cardiology Source Type: research

The Transition Trajectory for the Patient with a Traumatic Brain Injury
The trajectory status of patients with mild, moderate, and severe traumatic brain injury from emergency room evaluation, through acute care (intensive care if severe) and discharge is discussed. Additional considerations for elderly population and common complications associated with severe traumatic brain injury are also covered. (Source: Nursing Clinics of North America)
Source: Nursing Clinics of North America - June 15, 2019 Category: Nursing Authors: Ava M. Puccio, Maighdlin W. Anderson, Anita Fetzick Source Type: research

Physical Violence During Pregnancy in France: Frequency and Impact on the Health of Expectant Mothers and New-Borns
AbstractObjectives Even during pregnancy women may suffer from violence. We estimated the prevalence of physical abuse during pregnancy, we analyzed the main risk factors and described the relationship between physical violence, psychological wellbeing and pregnancy outcome.Methods We used a national representative sample of births, in all public and private maternity units, in 2016 in France. Women were interviewed after delivery, on their living conditions and occurrence of physical violence at least once during pregnancy. The study of risk factors and pregnancy outcome was done with multivariable logistic regressions.Re...
Source: Maternal and Child Health Journal - June 15, 2019 Category: Health Management Source Type: research

French clinical guidelines for peripheral motor nerve blocks in a PRM setting
Conclusion: These are the first organizational guidelines devoted to increase the security of motor nerve block use in PRM settings (Source: Annals of Physical and Rehabilitation Medicine)
Source: Annals of Physical and Rehabilitation Medicine - June 14, 2019 Category: Rehabilitation Source Type: research

Self-assessment
Publication date: Available online 14 June 2019Source: Anaesthesia & Intensive Care MedicineAuthor(s): Viyayanand Nadella (Source: Anaesthesia and intensive care medicine)
Source: Anaesthesia and intensive care medicine - June 14, 2019 Category: Anesthesiology Source Type: research

Functions of the placenta
Publication date: Available online 14 June 2019Source: Anaesthesia & Intensive Care MedicineAuthor(s): Leo Donnelly, Gillian CamplingAbstractThe placenta is an ephemeral materno-fetal organ with chorionic (fetal) villi bathed in maternal blood spaces, which allows restricted transfer of metabolites and drugs across specialized transfer areas. The placenta develops respiratory, nutritive and excretory functions while the fetal organs mature, and is also an important endocrine organ. (Source: Anaesthesia and intensive care medicine)
Source: Anaesthesia and intensive care medicine - June 14, 2019 Category: Anesthesiology Source Type: research

Uterine physiology
Publication date: Available online 14 June 2019Source: Anaesthesia & Intensive Care MedicineAuthor(s): Kamran Abbas, Suna D. Monaghan, Iain CampbellAbstractThe role of the uterus is to nurture the fetus until parturition. Functionally it consists of a lower cervix (which acts at different times as a passageway, a barrier and a reservoir) and an upper body in which the fetus develops. (Source: Anaesthesia and intensive care medicine)
Source: Anaesthesia and intensive care medicine - June 14, 2019 Category: Anesthesiology Source Type: research

Nutrition support for critically ill patients in China: role of the pharmacist.
CONCLUSIONS: This study demonstrated the unique perspectives offered and importance of having pharmacists as members of MDTs. PMID: 31192553 [PubMed - in process] (Source: Asia Pacific Journal of Clinical Nutrition)
Source: Asia Pacific Journal of Clinical Nutrition - June 14, 2019 Category: Nutrition Authors: Zhou X, Qiu F, Wan D, Sun S, Yao G, Liu Y, Li J Tags: Asia Pac J Clin Nutr Source Type: research

Barriers to enteral feeding of critically ill adults in Korea.
CONCLUSIONS: The findings support that the BEFIP-K is a feasible, valid instrument for assessing barriers to provision of enteral nutrition. PMID: 31192552 [PubMed - in process] (Source: Asia Pacific Journal of Clinical Nutrition)
Source: Asia Pacific Journal of Clinical Nutrition - June 14, 2019 Category: Nutrition Authors: Chang SJ, Kim H Tags: Asia Pac J Clin Nutr Source Type: research

The impact of daily use of an enteral feeding checklist on clinical outcomes in shock patients: a retrospective cohort study.
CONCLUSIONS: The use of an enteral feeding checklist in shock patients was associated with earlier enteral nutrition delivery and decreased intensive care unit stay. PMID: 31192551 [PubMed - in process] (Source: Asia Pacific Journal of Clinical Nutrition)
Source: Asia Pacific Journal of Clinical Nutrition - June 14, 2019 Category: Nutrition Authors: Mao Z, Yu Q, Liu C, Hu P, Hu X, Pan L, Kang H, Zhou F Tags: Asia Pac J Clin Nutr Source Type: research

Effects of Changes in ICU Bed Supply on ICU Utilization
Conclusions: Increases in ICU bed supply were associated with inconsistent changes in the probability of ICU admission that varied across patient subgroups. (Source: Medical Care)
Source: Medical Care - June 14, 2019 Category: Health Management Tags: Original Articles Source Type: research

Biomarker Predictors of Adverse Acute Kidney Injury Outcomes in Critically Ill Patients: The Dublin Acute Biomarker Group Evaluation Study
Conclusion: A clinical model incorporating severity of illness, patient demographics, and chronic illness with currently available clinical biomarkers of renal function was strongly predictive of development of AKI and associated clinical outcomes in a heterogeneous adult ICU population. The addition of urinary NGAL/albumin to this  simple clinical model improved the prediction of severe AKI, need for RRT and death, but not at a statistically or clinically significant level, when compared to the clinical model alone.Am J Nephrol (Source: American Journal of Nephrology)
Source: American Journal of Nephrology - June 14, 2019 Category: Neurology Source Type: research

Control of Gram-negative multi-drug resistant microorganisms in an Italian ICU: Rapid decline as a result of a multifaceted intervention, including conservative use of antibiotics
Acutely ill patients assisted in the Intensive Care Unit (ICU) are at high risk of both colonization and infection with Multidrug Resistant Organisms (MDROs) (Huskins, 2007; Landelle et al., 2014). Selection of MDROs in these patients may occur either as a consequence of prolonged exposure of resident microflora to wide spectrum antibiotic pressure (Bassetti et al., 2017; Meyer et al., 2010), or by nosocomial transfer (Richards et al., 1999; Warren et al., 2004). In recent years, an increased prevalence of Gram-negative bacteria with reduced or even absent sensitivity to currently available antibiotics (Gram-negative Multi...
Source: International Journal of Infectious Diseases - June 14, 2019 Category: Infectious Diseases Authors: Antonella Frattari, Vincenzo Savini, Ennio Polilli, Graziano Di Marco, Giuseppe Lucisano, Serena Corridoni, Tullio Spina, Alberto Costantini, Antonio Nicolucci, Paolo Fazii, Pierluigi Viale, Giustino Parruti Source Type: research

A Population-based Observational Study of Childhood Encephalitis in Children Admitted to Pediatric Intensive Care Units in England and Wales
Conclusions: These data suggest that encephalitis places a significant burden to the healthcare service. More work is needed to improve outcomes for children with encephalitis. (Source: The Pediatric Infectious Disease Journal)
Source: The Pediatric Infectious Disease Journal - June 14, 2019 Category: Infectious Diseases Tags: Original Studies Source Type: research

Bacterial Colonization of the Hospitalized Newborn: Competition Between: Staphylococcus aureus: and: Staphylococcus epidermidis
Background: In adults, Staphylococcus epidermidis and Staphylococcus aureus compete for colonization of the nasal mucosa and S. epidermidis strains that produce the Esp serine protease eradicate S. aureus nasal colonization. Whether similar phenomena are seen in newborn infants is unknown. Methods: Nasal swabs were obtained on admission and discharge from newborn infants (n = 90 and 83, respectively) in the neonatal intensive care unit at UC Davis Children’s Hospital. Swabs were cultured for S. aureus and S. epidermidis. S. epidermidis isolates were tested for Esp expression, overall secreted protease activity a...
Source: The Pediatric Infectious Disease Journal - June 14, 2019 Category: Infectious Diseases Tags: Original Studies Source Type: research

Enterovirus D68 Causing Acute Respiratory Infection: Clinical Characteristics and Differences With Acute Respiratory Infections Associated With Enterovirus Non-D68
Conclusions: EV-D68 circulated widely in Gipuzkoa during 2016 and was associated with severe ARI. In children with severe ARI of unknown etiology, the presence of EV-D68 should be considered. (Source: The Pediatric Infectious Disease Journal)
Source: The Pediatric Infectious Disease Journal - June 14, 2019 Category: Infectious Diseases Tags: Original Studies Source Type: research

The Clinical Presentation of Pediatric Mycoplasma pneumoniae Infections—A Single Center Cohort
Conclusions: MP-associated infection is a significant cause of hospitalization in the pediatric population including younger children ( (Source: The Pediatric Infectious Disease Journal)
Source: The Pediatric Infectious Disease Journal - June 14, 2019 Category: Infectious Diseases Tags: Original Studies Source Type: research

Use of Micafungin for the Prevention and Treatment of Invasive Fungal Infections in Everyday Pediatric Care in France: Results of the MYRIADE Study
Background: Invasive fungal infections are responsible for significant morbidity and mortality. Safety and effectiveness of antifungal agents is a particular concern in pediatric populations, where data are often limited. Micafungin is an echinocandin with demonstrated antifungal activity against a wide spectrum of Candida spp.; this subanalysis of data from the MYRIADE study describes the use of micafungin and its therapeutic outcomes in pediatric patients, in normal clinical practice. Methods: MYRIADE was an observational, multicenter, national, prospective, longitudinal study conducted from January 2010 to December...
Source: The Pediatric Infectious Disease Journal - June 14, 2019 Category: Infectious Diseases Tags: Antimicrobial Reports Source Type: research

Physicians' Perspectives on Adolescent and Young Adult Advance Care Planning The Fallacy of Informed Decision Making.
This study identified two categories important to the utility of ACP in pediatric HSCT patients; (1) the temporal context of ACP and decision making and (2) the limitations of pediatric ACP, with subcategories identified as (a) embodied and witnessed knowing, (b) the impact of clinical cascades-when the treatment of one organ system creates complications in another system that needs to be treated-and a creation of a "new normal" following complications of illness and its treatment in the pediatric intensive care unit (PICU), (c) the balancing of adolescents' autonomy with their capacity to make informed medical d...
Source: Journal of Clinical Ethics - June 14, 2019 Category: Medical Ethics Tags: J Clin Ethics Source Type: research

Impact of weekly case-based tele-education on quality of care in a limited resource medical intensive care unit
Limited critical care subspecialty training and experience is available in many low- and middle-income countries, creating barriers to the delivery of evidence-based critical care. We hypothesized that a struc... (Source: Critical Care)
Source: Critical Care - June 14, 2019 Category: Intensive Care Authors: Pedja Kovacevic, Sasa Dragic, Tijana Kovacevic, Danica Momcicevic, Emir Festic, Rahul Kashyap, Alexander S. Niven, Yue Dong and Ognjen Gajic Tags: Research Source Type: research

Minimizing catecholamines and optimizing perfusion
Catecholamines are used to increase cardiac output and blood pressure, aiming ultimately at restoring/improving tissue perfusion. While intuitive in its concept, this approach nevertheless implies to be effect... (Source: Critical Care)
Source: Critical Care - June 14, 2019 Category: Intensive Care Authors: Daniel De Backer and Pierre Foulon Tags: Review Source Type: research

NIV through the helmet can be used as first-line intervention for early mild and moderate ARDS: an unproven idea thinking out of the box
(Source: Critical Care)
Source: Critical Care - June 14, 2019 Category: Intensive Care Authors: Massimo Antonelli Tags: Review Source Type: research

Preserving the quality of life: nutrition in the ICU
Critically ill patients require adequate nutritional support to meet energy requirements both during and after intensive care unit (ICU) stay to protect against severe catabolism and prevent significant decond... (Source: Critical Care)
Source: Critical Care - June 14, 2019 Category: Intensive Care Authors: Pierre Singer Tags: Review Source Type: research

Sepsis: personalization v protocolization?
The founding tenet of evidence-based medicine is to combine best evidence with clinical expertise. As David Sackett opined ‘Without clinical expertise, practice risks becoming tyrannised by evidence’. Rigid pr... (Source: Critical Care)
Source: Critical Care - June 14, 2019 Category: Intensive Care Authors: Mervyn Singer Tags: Review Source Type: research

Ambulatory and stationary healthcare use in survivors of ARDS during the first year after discharge from ICU: findings from the DACAPO cohort
For many survivors of acute respiratory distress syndrome (ARDS), the process from discharge from intensive care unit (ICU) to recovery is long and difficult. However, healthcare use after discharge from ICU h... (Source: Annals of Intensive Care)
Source: Annals of Intensive Care - June 14, 2019 Category: Intensive Care Authors: Susanne Brandstetter, Frank Dodoo-Schittko, Magdalena Brandl, Sebastian Blecha, Thomas Bein and Christian Apfelbacher Tags: Research Source Type: research

Mesenchymal Stem/Stromal Cell Therapy for Bronchopulmonary Dysplasia in the Neonatal Intensive Care Unit
AbstractPurpose of ReviewClinical trials of mesenchymal stem/stromal cell (MSC) therapy for bronchopulmonary dysplasia (BPD) are already underway. A thorough understanding of the preclinical work that underpins these trials is critical for neonatal practitioners to properly evaluate them.Recent FindingsThe more significant advances have been in investigating the mechanisms of action by which MSCs are thought to ameliorate BPD, and the recognition that this therapeutic effect is largely contained within the non-cellular exosome fraction of MSCs.SummaryIn rodent hyperoxia models of BPD, MSCs have a pro-angiogenic effect medi...
Source: Current Pediatrics Reports - June 14, 2019 Category: Pediatrics Source Type: research

Singapore SPICE: Sedation Practices in Intensive Care Evaluation in Singapore - a prospective cohort study of the public healthcare system.
CONCLUSION: Sedation practices in Singapore ICUs are characterised by light sedation depth and low incidence of delirium. This may be due to the drugs used. PMID: 31197381 [PubMed - as supplied by publisher] (Source: Singapore Medical Journal)
Source: Singapore Medical Journal - June 14, 2019 Category: General Medicine Authors: Ng SY, Phua J, Wong YL, Kalyanasundaram G, Mukhopadhyay A, Lim D, Chia N, Ho BCH, Bailey MJ, Shehabi Y, Ti LK Tags: Singapore Med J Source Type: research

Airway management in inhalation injury: a case series.
We present a case series of five patients with inhalational burns who presented to Singapore General Hospital and discuss our approach to their early management, including early evaluation and planning for the upper and lower airway, coexisting cutaneous burns, and monitoring their ICU (intensive care unit) severity of illness, sepsis and acute respiratory distress syndrome. All five patients suffered various grades of inhalation injury. The patients were initially assessed by nasolaryngoscopy, and three patients were prophylactically intubated before being sent to the emergency operating theatre for definitive airway and ...
Source: Singapore Medical Journal - June 14, 2019 Category: General Medicine Authors: Desai SR, Zeng D, Chong SJ Tags: Singapore Med J Source Type: research

The EEG Ictal-Interictal Continuum-A Metabolic Roar But a Whimper of a Functional Outcome.
CONCLUSIONS: Metabolic activity increases monotonically with LPD frequency. Lateralized periodic discharge frequency should be a measure of interest when developing neuroprotection strategies in critical neurologic illness. Continuous Electroencephalography After Moderate to Severe Traumatic Brain Injury Lee H, Mizrahi MA, Hartings JA, Sharma S, Pahren L, Ngwenya LB, Moseley BD, Privitera M, Tortella FC, Foreman B. Crit Care Med. 2019;47(4):574-582. OBJECTIVES: After traumatic brain injury, continuous electroencephalography is widely used to detect electrographic seizures. With the development of standardized continuo...
Source: Epilepsy Curr - June 14, 2019 Category: Neurology Authors: Lee JW Tags: Epilepsy Curr Source Type: research

Monitoring of adult patient on venoarterial extracorporeal membrane oxygenation in intensive care medicine.
Authors: Merkle J, Azizov F, Fatullayev J, Weber C, Maier J, Eghbalzadeh K, Sabashnikov A, Pfister R, Wahlers T, Michels G Abstract Nowadays high-tech medical assist device therapy is a crucial part of intensive care medicine. Especially, management of circulatory assist device systems poses an increasing challenge for intensive care medicine. So far, autonomous recommendations for monitoring of extracorporeal life support systems in the form of guidelines or position papers are lacking. The purpose of this paper was to present an orientation guide on this important topic. PMID: 31183174 [PubMed] (Source: Journ...
Source: Journal of Thoracic Disease - June 13, 2019 Category: Respiratory Medicine Tags: J Thorac Dis Source Type: research

Less invasive ventricular enhancement (LIVE) as potential therapy for ischaemic cardiomyopathy end-stage heart failure.
Authors: Loforte A, Alfonsi J, Gliozzi G, Folesani G, Fiorentino M, Biffi M, Marinelli G, Di Bartolomeo R, Pacini D Abstract Background: Surgical ventricular reshaping (SVR) is a treatment option for patients with severe ischaemic heart failure (HF). Recently, a new minimally invasive, hybrid technique named "less invasive ventricular enhancement" (LIVE), has been developed adopting the Reviven™ Myocardial Anchoring System (BioVentrix Inc., San Ramon, CA, USA). Methods: Between January 2015 and November 2018, 7 patients (5 men and 2 women; mean age 72±8.9 years) underwent LIVE procedure a...
Source: Journal of Thoracic Disease - June 13, 2019 Category: Respiratory Medicine Tags: J Thorac Dis Source Type: research

Comparative evaluation of Airtraq ™ and GlideScope® videolaryngoscopes for difficult pediatric intubation in a Pierre Robin manikin
AbstractAirway management in children is associated with anatomical and physiological challenges compared with adults. Pierre Robin sequence (PRS) is a condition characterized by micrognathia, glossoptosis, and cleft palate and related to a difficult airway. Both the Airtraq ™ and GlideScope® have never been previously directly compared in PRS. Our aim was to evaluate the performance of these two airway devices in a PRS manikin for ethical and practical reasons. Between April and July 2017, 26, pediatric intensive care clinical fellows or trainees from a tertiary ped iatric center were recruited to participate. I...
Source: European Journal of Pediatrics - June 13, 2019 Category: Pediatrics Source Type: research

Hydrocellular Foam Versus Hydrocolloid Plate in the Prevention of Pressure Injuries.
CONCLUSIONS: Standard preventive measures combined with the use of either hydrocellular foam or hydrocolloid plate contributed to the prevention of pressure injuries in at-risk patients, with hydrocolloid plate being associated with significantly more discomfort during dressing removal. PMID: 31184996 [PubMed - as supplied by publisher] (Source: Wounds)
Source: Wounds - June 13, 2019 Category: General Medicine Tags: Wounds Source Type: research

Factors associated with mechanical restraint in the hospital environment: a cross-sectional study
Conclusion: This study estimated a high mechanical restraint prevalence in the hospital environment and determined factors associated with the risk of a patient being restrained. A medical restraint evaluation team is recommended for an in-depth analysis of indication and therapy.RESUMEN Objetivo: Estimar la prevalencia de contenci ón mecánica en el entorno hospitalario y los factores asociados con su realización. Método: Estudio transversal, observacional, con pacientes provenientes de un hospital público, de los sectores de clínica médica, clínica quirúrgica ...
Source: Revista da Escola de Enfermagem da USP - June 13, 2019 Category: Nursing Source Type: research

Intensive Care Unit Admission and Survival in Stage IV Cancer Patients with Septic Shock: A Population-Based Cohort Study
Conclusions: Though ICU admission with aggressive treatment may be associated with improved survival, the majority (70%) of stage IV cancer patients with septic shock were unable to survive until hospital discharge. (Source: Journal of Cancer)
Source: Journal of Cancer - June 13, 2019 Category: Cancer & Oncology Authors: Meng-Rui Lee, Chao-Lun Lai, K. Arnold Chan Tags: Research Paper Source Type: research

Biomarkers of Community-Acquired Pneumonia: A Key to Disease Diagnosis and Management.
Abstract Community-acquired pneumonia (CAP) is a dangerous disease caused by a spectrum of bacterial and viral pathogens. The choice of specific therapy and the need for hospitalization or transfer to the intensive care unit are determined by the causative agent and disease severity. The microbiological analysis of sputum largely depends on the quality of the material obtained. The prediction of severity and the duration of therapy are determined individually, and existing prognostic scales are used generally. This review examines the possibilities of using specific serological biomarkers to detect the bacterial o...
Source: Biomed Res - June 13, 2019 Category: Research Authors: Savvateeva EN, Rubina AY, Gryadunov DA Tags: Biomed Res Int Source Type: research

Benefits of red blood cell transfusion in patients with traumatic brain injury
(Source: Critical Care)
Source: Critical Care - June 13, 2019 Category: Intensive Care Authors: Weimin Zhang, Kailei Du and Xuping Chen Tags: Letter Source Type: research