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Vasoactive Inotropic Score as a Predictor of Mortality in Adult Patients With Cardiogenic Shock: Medical Therapy Versus ECMO
Conclusions A high level of vasoactive inotropic support during the first 48hours was significantly associated with increased in-hospital mortality in adult CS patients. (Source: Revista Espanola de Cardiologia)
Source: Revista Espanola de Cardiologia - February 18, 2018 Category: Cardiology Source Type: research

Supraclavicular catheterization of the brachiocephalic vein: a way to prevent or reduce catheter maintenance-related complications in children
AbstractPlacement of a central venous catheter (CVC) in the brachiocephalic vein (BCV) via the ultrasound (US)-guided supraclavicular approach was recently described in children. We aimed to determine the CVC maintenance-related complications at this site compared to the others (i.e., the femoral, the subclavian, and the jugular). We performed a retrospective data collection of prospectively registered data on CVC in young children hospitalized in a pediatric intensive care unit (PICU) during a 4-year period (May 2011 to May 2015). The primary outcome was a composite of central line-associated bloodstream infection (CLABSI...
Source: European Journal of Pediatrics - February 17, 2018 Category: Pediatrics Source Type: research

Predictors of long-term adherence to continuous positive airway pressure in patients with obstructive sleep apnoea and acute coronary syndrome.
Authors: Florés M, Martinez-Alonso M, Sánchezde-la-Torre A, Aldomà A, Galera E, Barbé F, Sánchezde-la-Torre M, Dalmases M Abstract Background: Continuous positive airway pressure (CPAP) is an effective treatment for obstructive sleep apnoea (OSA), but an evaluation of CPAP adherence is rarely carried out among patients with acute coronary syndrome (ACS). The goals of the study are to analyse long-term adherence and identify the predictors of non-compliance with CPAP treatment for patients with non-sleepy OSA and ACS. Methods: This is an ancillary study of the ISAACC study, whi...
Source: Journal of Thoracic Disease - February 17, 2018 Category: Respiratory Medicine Tags: J Thorac Dis Source Type: research

Technique and Outcomes of Less Invasive Lung Retransplantation
Conclusions Less invasive retransplantation of the lung via sternum-sparing anterolateral thoracotomies and off-pump is a safe procedure with low associated morbidity and favorable midterm survival. (Source: Transplantation)
Source: Transplantation - February 17, 2018 Category: Transplant Surgery Tags: Original Clinical Science—General Source Type: research

Ferulic acid protects lipopolysaccharide-induced acute kidney injury by suppressing inflammatory events and upregulating antioxidant defenses in Balb/c mice
This study aimed to investigate the effect of FA on LPS-induced AKI in mice model and to understand the protective mechanisms involved, to provide evidence for FA in the treatment of AKI. Balb/c mice were treated with FA at 50 mg/kg and 100 mg/kg dosages after LPS stimulation (10 mg/kg). At the end of the intervention, we determined the concentrations of serum creatinine and blood urea nitrogen, inflammatory cytokines and histopathological changes in animals. Also, the relative protein expression level of TLR4 mediated NF-κB signaling pathway were studied in kidney tissues. FA treated animals showed upregulatio...
Source: Biomedicine and Pharmacotherapy - February 17, 2018 Category: Drugs & Pharmacology Source Type: research

Candida albicans - Biology, molecular characterization, pathogenicity, and advances in diagnosis and control – An update
Publication date: Available online 16 February 2018 Source:Microbial Pathogenesis Author(s): Maryam Dadar, Ruchi Tiwari, Kumaragurubaran Karthik, Sandip Chakraborty, Youcef Shahali, Kuldeep Dhama Candida albicans is an emerging multidrug-resistant fungal pathogen representing an important source of invasive disease in humans and generating high healthcare costs worldwide. This fungus is frequently found in different anatomical sites of healthy persons and could induce systemic and superficial infections under optimal environmental conditions. Invasive candidiasis (IC) is an important nosocomial infection with high morbidi...
Source: Microbial Pathogenesis - February 17, 2018 Category: Infectious Diseases Source Type: research

Clinical features and peripartum outcomes in pregnant women with cardiac disease: a nationwide retrospective cohort study in Japan
AbstractAlthough the number of pregnancies in women with cardiac disease is increasing worldwide, there are few data concerning their clinical characteristics and peripartum outcomes. Using the Diagnosis Procedure Combination database between 2008 and 2014 in Japan, we retrospectively identified pregnant women who underwent high-risk delivery due to obstetric or non-obstetric comorbidities. We classified eligible women into those with pre-existing cardiac disease (cardiac disease group) and those with non-cardiac comorbidities (non-cardiac disease group) and compared their characteristics and peripartum outcomes. Of 94,364...
Source: Heart and Vessels - February 17, 2018 Category: Cardiology Source Type: research

Overview of colorectal resections in a reference center in Curitiba – Brazil: Experience with open and laparoscopic approach
Conclusions Videolaparoscopic approach is a safe and effective option in the treatment of colorectal diseases. Surgery duration and anastomotic fistula rates are similar to the open resections. Hospital stay and ICU stay durations, however, were shorter in patients submitted to laparoscopic colectomies. (Source: Journal of Coloproctology)
Source: Journal of Coloproctology - February 17, 2018 Category: Gastroenterology Source Type: research

Pattern of Gram-negative bloodstream infections and their antibiotic susceptibility profiles in a neonatal intensive care unit
Publication date: March 2018 Source:Journal of Hospital Infection, Volume 98, Issue 3 Author(s): F. Sana, L. Satti, G. Zaman, A. Gardezi, A. Imtiaz, A. Ahmed, M.T. Khadim (Source: Journal of Hospital Infection)
Source: Journal of Hospital Infection - February 17, 2018 Category: Infectious Diseases Source Type: research

Control of endemic multidrug-resistant Gram-negative bacteria after removal of sinks and implementing a new water-safe policy in an intensive care unit
Conclusion The implementation of a new water-safe policy, which included the removal of sinks from all patient rooms, successfully improved the control of MDR-GNB spread in an ICU with endemic infection. Our results support the contribution of sink use with the incidence of MDR-GNB in endemic environments. (Source: Journal of Hospital Infection)
Source: Journal of Hospital Infection - February 17, 2018 Category: Infectious Diseases Source Type: research

Outbreak of Burkholderia cepacia pseudobacteraemia caused by intrinsically contaminated commercial 0.5% chlorhexidine solution in neonatal intensive care units
Conclusions The pseudobacteraemia cases were caused by contaminated 0.5% CHG produced by a single manufacturer. Stricter government regulation is needed to prevent contamination of disinfectants during manufacturing. In addition, microbial contamination of antiseptics and disinfectants should be suspected when a B. cepacia outbreak occurs in hospitalized patients. (Source: Journal of Hospital Infection)
Source: Journal of Hospital Infection - February 17, 2018 Category: Infectious Diseases Source Type: research

Clonal spread of carbapenem-resistant Acinetobacter baumannii in a neonatal intensive care unit
This study describes a clonal spread of carbapenem-resistant A. baumannii (CRAB) isolates in an NICU. In total, 21 CRAB isolates were collected from premature newborns. Only polymyxin B was active against such isolates. Nineteen CRAB isolates were clonally related (Cluster C, which belonged to worldwide-disseminated ST1). All newborns had peripheral access and had received β-lactam therapy previously. The implementation of strict infection control measures was of fundamental importance to eradicate the clonal type in the study hospital. (Source: Journal of Hospital Infection)
Source: Journal of Hospital Infection - February 17, 2018 Category: Infectious Diseases Source Type: research

Ventilator-associated events as a quality indicator in intensive care units
Publication date: Available online 16 February 2018 Source:Journal of Hospital Infection Author(s): M.C.S. de Almeida, E.A.S. Medeiros, F. Agena, C.C. Oliveira, M.V.Y. Swawamura, S.F. Costa, M.J.C. Carmona, L.M. de Sa Malbouisson (Source: Journal of Hospital Infection)
Source: Journal of Hospital Infection - February 17, 2018 Category: Infectious Diseases Source Type: research

Health professionals ’ perceptions about their clinical performance and the influence of audit and feedback on their intentions to improve practice: a theory-based study in Dutch intensive care units
Audit and feedback aims to guide health professionals in improving aspects of their practice that need it most. Evidence suggests that feedback fails to increase accuracy of professional perceptions about clin... (Source: Implementation Science)
Source: Implementation Science - February 17, 2018 Category: Health Management Authors: Wouter T. Gude, Marie-Jos é Roos-Blom, Sabine N. van der Veer, Dave A. Dongelmans, Evert de Jonge, Jill J. Francis, Niels Peek and Nicolette F. de Keizer Tags: Research Source Type: research

Prediction of parental posttraumatic stress, anxiety and depression after a child's critical hospitalization
To study the role of parental resilience, emotions accessed during admission and perceived stress in predicting the degree of parental posttraumatic stress disorder (PTSD), anxiety and depression symptoms after a child's treatment in intensive care. (Source: Journal of Critical Care)
Source: Journal of Critical Care - February 17, 2018 Category: Intensive Care Authors: Roc ío Rodríguez-Rey, Jesús Alonso-Tapia, Gillian Colville Source Type: research

Fluid therapy and outcome: a prospective observational study in 65 German intensive care units between 2010 and 2011
Outcome data on fluid therapy in critically ill patients from randomised controlled trials may be different from data obtained by observational studies under “real-life” conditions. We conducted this prospecti... (Source: Annals of Intensive Care)
Source: Annals of Intensive Care - February 17, 2018 Category: Intensive Care Authors: Christian Ertmer, Bernhard Zwi ßler, Hugo Van Aken, Michael Christ, Fabian Spöhr, Axel Schneider, Robert Deisz and Matthias Jacob Tags: Research Source Type: research

Beyond Pain: Nurses ’ Assessment of Patient Suffering, Dignity, and Dying in the Intensive Care Unit
Deaths in the Intensive Care Unit (ICU) are increasingly common in the United States, yet little is known about patients ’ experiences at the end-of-life in the ICU. (Source: Journal of Pain and Symptom Management)
Source: Journal of Pain and Symptom Management - February 17, 2018 Category: Palliative Care Authors: Amanda Su, Lindsay Lief, David Berlin, Zara Cooper, Daniel Ouyang, John Holmes, Renee Maciejewski, Paul K. Maciejewski, Holly G. Prigerson Source Type: research

Effect of primary admission to burn centers on the outcomes of severely burned patients
Burns represent a special form of severe trauma which can negatively affect nearly every organ system [1]. Despite considerable advances regarding intensive care at burn centers, severe burns remain associated with high long-term morbidity- and mortality rates [2,3]. On a global scale, current estimates indicate that annually about 6 million patients worldwide need medical treatment for various extends of burns [4]. Depending on the local circumstances, the majority of burn victims receive initial care at local hospitals prior to transfer to a burn center or are entirely treated at non-specialized peripheral hospitals [4 &...
Source: Burns : Journal of the International Society for Burn Injuries - February 17, 2018 Category: Cosmetic Surgery Authors: Denis Ehrl, Paul I. Heidekrueger, Milomir Ninkovic, P. Niclas Broer Source Type: research

Re: Oxalate Nephropathy following Vitamin C Intake within Intensive Care Unit
E. Colliou, A. Mari, A. Delas, A. Delarche and S. Faguer (Source: The Journal of Urology)
Source: The Journal of Urology - February 17, 2018 Category: Urology & Nephrology Authors: Dean G. Assimos Tags: Urological Survey Source Type: research

Are rehabilitation outcomes after severe anoxic brain injury different from severe traumatic brain injury? A matched case–control study
Many reports have investigated rehabilitation outcomes after a traumatic brain injury (TBI); however, comparably less is known about whether they differ from outcomes of an anoxic brain injury (ABI). Thus, we aimed to compare the rehabilitation outcomes of patients with ABI with control patients who have TBI. Forty participants with ABI and 40 participants with TBI were included in this retrospective study. Participants with ABI were matched with participants with TBI who had similar clinical characteristics such as age, initial Functional Independence Measurement (FIM) score, and duration of coma. FIM and Functional Ambul...
Source: International Journal of Rehabilitation Research - February 16, 2018 Category: Rehabilitation Tags: Original articles Source Type: research

Association of direct bilirubin level with postoperative outcome in critically ill postoperative patients.
Authors: Nagae M, Egi M, Kubota K, Makino S, Mizobuchi S Abstract Background: Hyperbilirubinemia is a common postoperative complication. Elevated direct bilirubin (D-Bil) and indirect bilirubin (I-Bil) levels are related to different pathophysiologies; therefore, their associations with outcomes also differ. However, there have been few comparative studies of such associations in postoperative patients. Methods: This retrospective study compared the associations of postoperative D-Bil and I-Bil with outcomes. We included adult patients requiring postoperative intensive care for more than 48 hours between 2008 a...
Source: Korean Journal of Anesthesiology - February 16, 2018 Category: Anesthesiology Tags: Korean J Anesthesiol Source Type: research

Risk Modeling to Optimize Patient Selection for Management of the Descending Thoracic Aortic Aneurysm
Conclusions In older patients with significant comorbidities, TEVAR demonstrated superior results compared with OSR and may be preferable in this target population. (Source: The Annals of Thoracic Surgery)
Source: The Annals of Thoracic Surgery - February 16, 2018 Category: Cardiovascular & Thoracic Surgery Source Type: research

Cardiac Surgery Outcomes in Abdominal Solid Organ Transplant Recipients
Conclusions Previous history of abdominal transplant is associated with an increased 30-day incidence of stroke after cardiac surgery. Abdominal transplant does not affect 30-day mortality after cardiac surgery, whereas long-term survival is significantly reduced. Regular patient follow-up and prevention and early treatment of postoperative complications are key to patient survival. (Source: The Annals of Thoracic Surgery)
Source: The Annals of Thoracic Surgery - February 16, 2018 Category: Cardiovascular & Thoracic Surgery Source Type: research

Assessment of bedside transfusion practices at a tertiary care center: A step closer to controlling the chaos
Conclusion: There is need to create awareness about policies and guidelines of bed side transfusion among the ward staff. Regular audits are necessary for compliance to guidelines among clinical staff. (Source: Asian Journal of Transfusion Science)
Source: Asian Journal of Transfusion Science - February 16, 2018 Category: Hematology Authors: Dheeraj Khetan Rahul Katharia Hem Chandra Pandey Rajendra Chaudhary Rajesh Harsvardhan Hemchandra Pandey Atul Sonkar Source Type: research

Transfusion support in preterm neonates & #60;1500 g and/or & #60;32 weeks in a tertiary care center: A descriptive study
Conclusion: This study would serve as an audit for neonatal blood transfusion therapy. Close adherence to neonatal transfusion policy and restrictive transfusion guidelines helps reduce inappropriate use of blood products and adverse transfusion reactions. (Source: Asian Journal of Transfusion Science)
Source: Asian Journal of Transfusion Science - February 16, 2018 Category: Hematology Authors: RA Shanmugha Priya R Krishnamoorthy Vinod Kumar Panicker Binu Ninan Source Type: research

Moving Forward to Improve Safety and Quality of Neonatal Intensive Care in Korea.
Authors: Chang YS PMID: 29441743 [PubMed - in process] (Source: Journal of Korean Medical Science)
Source: Journal of Korean Medical Science - February 15, 2018 Category: Biomedical Science Tags: J Korean Med Sci Source Type: research

Clinical and Laboratory Profile of Zika and Dengue Infected Patients: Lessons Learned From the Co-circulation of Dengue, Zika and Chikungunya in Brazil
This study accessed the patients information on demographic characteristics, physical signs and symptoms. Study population This is a cross-sectional and observational study carried out in Brazil during DENV and ZIKV epidemic occurred in 2016. Patients were assisted at the Healthy Unit UPA Coronel Antonino in Campo Grande, MS, Brazil from February to March of 2016. During the study 134 suspected arboviral infection cases were included and submitted to investigation. Patients presenting fever, rash during acute phase of infection (up to the 7th day after disease onset) followed by at least two of the following signals a...
Source: PLOS Currents Outbreaks - February 15, 2018 Category: Epidemiology Authors: Elzinandes Leal de Azeredo Source Type: research

Nursing Intensive ‐Care Satisfaction Scale [NICSS]: Development and validation of a patient‐centered instrument
ConclusionsThe scale has been designed and validated incorporating the perspective of critical care patients. Thanks to its reliability and validity, this questionnaire can be used both in research and in clinical practice. The scale offers a possibility to assess and develop interventions to improve patient satisfaction with nursing care.This article is protected by copyright. All rights reserved. (Source: Journal of Advanced Nursing)
Source: Journal of Advanced Nursing - February 15, 2018 Category: Nursing Authors: M Romero ‐García, L de la Cueva‐Ariza, Ll Benito‐Aracil, T.M Lluch‐Canut, J Trujols‐Albet, M. A Martínez‐Momblan, M. E Juvé‐Udina, P Delgado‐Hito Tags: Research Methodology: Instrument Development Source Type: research

Resource Use During the Last 6 Months of Life of Individuals Dying with and of Alzheimer's Disease
ConclusionDuring the last 6 months of life, individuals dying of AD used fewer intensive resources such as intensive care unit, cardiopulmonary resuscitation, and invasive ventilation than those dying with AD, which suggests the effect of recognition of an end‐of‐life phase. Overall, individuals with AD rarely used palliative care services, suggesting a need for more efforts to encourage use of palliative care in individuals with AD. (Source: Journal of the American Geriatrics Society)
Source: Journal of the American Geriatrics Society - February 15, 2018 Category: Geriatrics Authors: Kristof Faes, Joachim Cohen, Lieven Annemans Tags: Clinical Investigation Source Type: research

Fournier's gangrene: a 10 ‐year review and validation of mortality predictors in a hong kong major regional centre
ConclusionElderly, smokers, diabetics or immunocompromised, higher creatinine or lower haematocrit level and patients requiring orchidectomy indicate poorer prognosis and may benefit from intensive care. Current scoring systems either perform poorly or have troublesome frontline application. This represents the first local study of such intent. (Source: Surgical Practice)
Source: Surgical Practice - February 15, 2018 Category: Surgery Authors: Brian yin on Chan, Ben wui bun Wong, Kelly ka yee Lo, Carmen Yim, Cyrus tak yin Tse Tags: Original Article Source Type: research

Comparison of European ICU patients in 2012 (ICON) versus 2002 (SOAP)
AbstractPurposeTo evaluate differences in the characteristics and outcomes of intensive care unit (ICU) patients over time.MethodsWe reviewed all epidemiological data, including comorbidities, types and severity of organ failure, interventions, lengths of stay and outcome, for patients from the Sepsis Occurrence in Acutely ill Patients (SOAP) study, an observational study conducted in European intensive care units in 2002, and the Intensive Care Over Nations (ICON) audit, a survey of intensive care unit patients conducted in 2012.ResultsWe compared the 3147 patients from the SOAP study with the 4852 patients from the ICON ...
Source: Intensive Care Medicine - February 15, 2018 Category: Intensive Care Source Type: research

Are outpatient clinics justified in intensive care medicine?
Publication date: Available online 14 February 2018 Source:Medicina Intensiva (English Edition) Author(s): P. Extremera, J.M. Añón, A. García de Lorenzo (Source: Medicina Intensiva)
Source: Medicina Intensiva - February 15, 2018 Category: Intensive Care Source Type: research

Adenovirus types associated with severe respiratory diseases: a retrospective four ‐year study in Kuwait
This article is protected by copyright. All rights reserved (Source: Journal of Medical Virology)
Source: Journal of Medical Virology - February 15, 2018 Category: Virology Authors: Wassim Chehadeh, Anfal Al ‐Adwani, Sonia Elezebeth John, Shaikhah Al‐Dhufairi, Hessa Al‐Dousari, Maha Alkhaledi, Widad Al‐Nakib Tags: Research Article Source Type: research

Preoperative Risk Factors for Unexpected Postoperative Intensive Care Unit Admission: A Retrospective Case Analysis
Conclusions CHF, acute/chronic kidney injury, PVD, and valve disease were significantly associated with increased unexpected ICU admission; patients with CVA suffered increased mortality when admitted to the ICU. (Source: Anaesthesia, Critical Care and Pain Medicine)
Source: Anaesthesia, Critical Care and Pain Medicine - February 15, 2018 Category: Anesthesiology Source Type: research

Sevoflurane For Procedural Sedation In Critically Ill Patients: A Pharmacokinetic Comparative Study Between Burn And Non-Burn Patients
Conclusion We observed an increased volume of distribution, slower elimination rate, and altered metabolism of sevoflurane in burn patients compared to controls. Repeated use for procedural sedation in burn patients needs further evaluation. No renal toxicity was detected. Trial registry number ClinicalTrials.gov Identifier NCT02048683 (Source: Anaesthesia, Critical Care and Pain Medicine)
Source: Anaesthesia, Critical Care and Pain Medicine - February 15, 2018 Category: Anesthesiology Source Type: research

The patient journey to home after major cardiac surgery in infancy
Major technological advances in pediatric surgical and intensive care in recent decades, particularly for neonates, have resulted in the survival of children with previously life-threatening congenital heart defects (CHDs) including those with significant comorbidities. Despite these positive steps forward, many cardiac infants remain medically vulnerable after surgery hence the process of discharge home as well as the period early after discharge are crucial phases in the patient journey. In order to ensure children achieve the best outcomes and parents are adequately supported in caring for them, preparation for discharg...
Source: Progress in Pediatric Cardiology - February 15, 2018 Category: Cardiology Authors: Kate L. Brown, Liz Smith Tags: Review Source Type: research

Prevalence, Location, and Characteristics of Chronic Pain in Intensive Care Survivors
A growing number of studies have addressed the long-term consequences of intensive care unit (ICU) treatment, but few have studied the prevalence of chronic pain and pain characteristics longitudinally. The goal of the work described here was to investigate the prevalence and characteristics of chronic pain in ICU survivors 3  months and 1 year after ICU discharge and to identify risk factors for chronic pain 1 year after ICU discharge. The design used was an explorative and longitudinal study. The patients in this work had stayed>48  hours in two mixed ICUs in Oslo University Hospital, a tertiary re...
Source: Pain Management Nursing - February 15, 2018 Category: Nursing Authors: Anne Kathrine Langerud, Tone Rust øen, Cathrine Brunborg, Ulf Kongsgaard, Audun Stubhaug Tags: Original Article Source Type: research

Vascular-induced lung injury: another advocate for personalized ARDS management
(Source: Intensive Care Medicine)
Source: Intensive Care Medicine - February 15, 2018 Category: Intensive Care Source Type: research

Position paper for the organization of ECMO programs for cardiac failure in adults
AbstractExtracorporeal membrane oxygenation (ECMO) has been used increasingly for both respiratory and cardiac failure in adult patients. Indications for ECMO use in cardiac failure include severe refractory cardiogenic shock, refractory ventricular arrhythmia, active cardiopulmonary resuscitation for cardiac arrest, and acute or decompensated right heart failure. Evidence is emerging to guide the use of this therapy for some of these indications, but there remains a need for additional evidence to guide best practices. As a result, the use of ECMO may vary widely across centers. The purpose of this document is to highligh...
Source: Intensive Care Medicine - February 15, 2018 Category: Intensive Care Source Type: research

The American Association of Heart Failure Nurses (AAHFN) certification review course: the impact on heart failure nurses' knowledge
Heart failure (HF) is a complex, chronic cardiovascular condition with an estimated prevalence of 6.5 million Americans aged 20 years or older.1 HF is associated with morbidity that often results in hospitalization for disease instability and nurses are a critical component of the healthcare team promoting quality care for patients during both acute crisis and periods of stability. In the hospital setting, nurses are the primary providers of patient discharge instructions, including education on HF self-care. (Source: Heart and Lung)
Source: Heart and Lung - February 15, 2018 Category: Intensive Care Authors: Kelley M. Anderson, Cynthia Bither, Natalie Andon Source Type: research

Health-care spending and utilization for children discharged from a neonatal intensive care unit
Health-care spending and utilization for children discharged from a neonatal intensive care unit, Published online: 15 February 2018; doi:10.1038/s41372-018-0055-5Health-care spending and utilization for children discharged from a neonatal intensive care unit (Source: Journal of Perinatology)
Source: Journal of Perinatology - February 15, 2018 Category: Perinatology & Neonatology Authors: Dennis Z. Kuo Jay G. Berry Matt Hall Robert E. Lyle Christopher J. Stille Source Type: research

Reframing pediatric cardiac intensive care outcomes: The importance of the family and the role of pediatric medical traumatic stress
With mortality in the pediatric cardiac intensive care unit (CICU) low at 2 –4%, the majority of children survive their admission. While the CICU experience is often part of a broader story of living with and managing cardiac disease, many children are impacted by CICU experience with changes to their physical health, neurocognition, psychological health, and quality of l ife. Risk factors for poor outcomes after a CICU admission include potentially fixed and immutable factors such as congenital heart disease severity, therapeutic interventions, and hospitalization characteristics. (Source: Progress in Pediatric Cardiology)
Source: Progress in Pediatric Cardiology - February 15, 2018 Category: Cardiology Authors: Lauren M. Yagiela, Felicity Harper, Kathleen Meert Tags: Review Source Type: research

Prognostic and Pathogenic Role of Angiopoietin-1 and -2 in Pneumonia.
CONCLUSIONS: These data suggest a central role of Angiopoietin-1/-2 in pneumonia-evoked inflammation and permeability. Increased Angiopoietin-2 serum levels predicted mortality and length of hospital stay, and Angiopoietin-1 may provide a therapeutic target for severe pneumonia. PMID: 29447449 [PubMed - as supplied by publisher] (Source: American Journal of Respiratory and Critical Care Medicine)
Source: American Journal of Respiratory and Critical Care Medicine - February 15, 2018 Category: Respiratory Medicine Authors: Gutbier B, Neuhauß AK, Reppe K, Ehrler C, Santel A, Kaufmann J, Scholz M, Weissmann N, Morawietz L, Mitchell TJ, Aliberti S, Hippenstiel S, Suttorp N, Witzenrath M, CAPNETZ and PROGRESS study groups Tags: Am J Respir Crit Care Med Source Type: research

Treatment of pulmonary hypertension with inhaled agents in the pediatric intensive care unit.
PMID: 29436464 [PubMed - in process] (Source: American Journal of Health-System Pharmacy : AJHP)
Source: American Journal of Health-System Pharmacy : AJHP - February 14, 2018 Category: Drugs & Pharmacology Authors: Gillis HC, Fischer G, Gupta S Tags: Am J Health Syst Pharm Source Type: research

Clinical Outcomes of Lung Transplantation: Experience at Asan Medical Center.
Conclusion: Despite a high percentage of patients who required preoperative intensive care, the transplantation outcomes were acceptable. PMID: 29430425 [PubMed] (Source: Korean Journal of Thoracic and Cardiovascular Surgery)
Source: Korean Journal of Thoracic and Cardiovascular Surgery - February 14, 2018 Category: Cardiovascular & Thoracic Surgery Tags: Korean J Thorac Cardiovasc Surg Source Type: research

Mid-Term Results of Minimally Invasive Direct Coronary Artery Bypass Grafting.
Conclusion: MIDCAB is a safe procedure with low postoperative morbidity and mortality and favorable mid-term MACCE-free survival. PMID: 29430423 [PubMed] (Source: Korean Journal of Thoracic and Cardiovascular Surgery)
Source: Korean Journal of Thoracic and Cardiovascular Surgery - February 14, 2018 Category: Cardiovascular & Thoracic Surgery Tags: Korean J Thorac Cardiovasc Surg Source Type: research

Haloperidol for delirium in critically ill patients – protocol for a systematic review
The objective of this systematic review was to critically access the evidence of randomised clinical trials on the effects of haloperidol vs. placebo or any other agents for delirium in critically ill patients. MethodsWe will search for randomised clinical trials in the following databases: Cochrane Library, MEDLINE, EMBASE, Science Citation Index, BIOSIS, Cumulative Index to Nursing and Allied Health Literature, Latin American and Caribbean Health Sciences Literature, and Allied and Complementary Medicine Database. Two authors will independently screen and select references for inclusion using Covidence, extract data and ...
Source: Acta Anaesthesiologica Scandinavica - February 14, 2018 Category: Anesthesiology Authors: M. Barbateskovic, S. R. Kraus, M. O. Collet, O. Mathiesen, J. C. Jakobsen, A. Perner, J. Wetterslev Tags: Special Article Source Type: research

Obstructive Hydrocephalus Due to Intraventricular Hemorrhage After Incidental Durotomy During Lumbar Spine Surgery
Conclusion. Obstructive hydrocephalus after intraventricular hemorrhage is an exceptionally rare but potentially life-threatening complication of incidental durotomies. Spine surgeons should be aware of this rare but serious complication. Level of Evidence: 4 (Source: Spine)
Source: Spine - February 14, 2018 Category: Orthopaedics Tags: Case Report Source Type: research

Physical Activity of ICU Survivors during Acute Admission: Agreement of the activPAL with Observation.
Conclusion: Because it underestimated step count, the activPAL likely incorrectly recorded stepping time as standing time, so that time spent upright was the measure of activity with the smallest error. Sedentary behaviour, including frequency of transitions, was validly assessed. PMID: 29434419 [PubMed - in process] (Source: Physiotherapy Canada)
Source: Physiotherapy Canada - February 14, 2018 Category: Physiotherapy Authors: Baldwin CE, Johnston KN, Rowlands AV, Williams MT Tags: Physiother Can Source Type: research

Characteristics and outcomes of patients who underwent bedside surgical tracheostomy performed in the intensive care unit: a retrospective study
(Source: Canadian Journal of Anesthesia)
Source: Canadian Journal of Anesthesia - February 14, 2018 Category: Anesthesiology Source Type: research