COVID-19-Related Neuropsychiatric Symptoms in Patients With Alcohol Abuse Conditions During the SARS-CoV-2 Pandemic: A Retrospective Cohort Study Using Real World Data From Electronic Health Records of a Tertiary Hospital
Patients with an alcohol abuse disorder exhibit several medical characteristics and social determinants, which suggest a greater vulnerability to the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and a worse course of the coronavirus disease 2019 (COVID-19) once infected. During the first wave of the COVID-19, most of the countries have register an increase in alcohol consumption. However, studies on the impact of alcohol addiction on the risk of COVID-19 infection are very scarce and inconclusive. This research offers a descriptive observational retrospective cohort study using real world data obt...
Source: Frontiers in Neurology - March 3, 2021 Category: Neurology Source Type: research

Characterization of Carbapenem-Resistant Klebsiella pneumoniae ST15 Clone Coproducing KPC-2, CTX-M-15 and SHV-28 Spread in an Intensive Care Unit of a Tertiary Hospital
(Source: Infection and Drug Resistance)
Source: Infection and Drug Resistance - March 2, 2021 Category: Infectious Diseases Tags: Infection and Drug Resistance Source Type: research

Caregiver willingness to provide care in the ICU: A concept analysis
ConclusionThe definition provides a foundation for instrument development to measure caregiver willingness and possible theory expansion for family engagement and caregiving in the ICU. (Source: Nursing Forum)
Source: Nursing Forum - March 2, 2021 Category: Nursing Authors: Cindy Wilk, Amy Petrinec Tags: CONCEPT ANALYSIS Source Type: research

Difficult-to-engage patients: What evolution after discharge from Assertive Community Programs?
CONCLUSIONS: This study provides insight on the sustainability of the benefits of ACT programs, suggesting that these interventions can help patients who are refractory to care to gain clinical and psychosocial improvement in the long term. Our results also suggest that baseline severity as well as early improvements after six months of treatment were associated with larger improvement at follow up. These clinical predictors provide some help to distinguish which patients are more likely to benefit from an ACT approach.PMID:33648751 | DOI:10.1016/j.encep.2020.10.003 (Source: L Encephale)
Source: L Encephale - March 2, 2021 Category: Psychiatry Authors: S Vidal L Correa N Perroud P Huguelet Source Type: research

Abdominal Decompression after Cardiac Surgery: Outcome of 42 Patients with Abdominal Compartment Syndrome
ConclusionAbdominal compartment syndrome is a rare but serious complication after cardiac surgery with a high mortality rate. Independent risk factors for ACS were identified. Negative pressure wound therapy seems to promote and allow early fascia closure of the abdomen and represents therefore a likely benefit for the patient. (Source: World Journal of Surgery)
Source: World Journal of Surgery - March 2, 2021 Category: Surgery Source Type: research

Implementing Prone Positioning for COVID-19 Patients Outside the Intensive Care Unit
Conclusions: Implementation of a new nursing protocol is possible with strong unit-based support, even during a pandemic. (Source: Journal of Nursing Care Quality)
Source: Journal of Nursing Care Quality - March 2, 2021 Category: Nursing Tags: Articles Source Type: research

Implementation of an Intensive Care Unit Diary Program at a Veterans Affairs Hospital
Conclusions: The ICU diary is a cost-effective and efficient intervention to help patients and family members cope with the burden of critical illness. (Source: Journal of Nursing Care Quality)
Source: Journal of Nursing Care Quality - March 2, 2021 Category: Nursing Tags: Articles Source Type: research

Obesity pandemic during COVID-19 outbreak: Narrative review and future considerations
The high prevalence of obesity and obesity-related comorbidities has reached pandemic proportions, particularly in Western countries. Obesity increases the risk to develop several chronic noncommunicable disease, ultimately contributing to reduced survival. Recently, obesity has been recognized as major risk factor for coronavirus disease-19 (COVID-19)-related prognosis, contributing to worse outcomes in those with established COVID-19. Particularly, obesity has been associated with higher hospitalization rates in acute or intensive care and greater risk for invasive mechanical ventilation than lean people. (Source: Clinical Nutrition)
Source: Clinical Nutrition - March 2, 2021 Category: Nutrition Authors: Edda Cava, Barbara Neri, Maria Grazia Carbonelli, Sergio Riso, Salvatore Carbone Tags: Narrative Review Source Type: research

Patient – practitioner communication and contact lens compliance during a prolonged COVID-19 lockdown
Following the statement of the Health World Organization declaring coronavirus disease 2019 (COVID-19) a pandemic [1], the rapidly increasing number of contagions and foreseeable saturation of the public and private health service intensive care units in Spain prompted the declaration of a nationwide State of Alarm on March 13, 2020, and a lockdown of all non-essential sectors was imposed on March 14, 2020. On April 28, 2020, the government announced a plan for easing lockdown restrictions consisting of four de-escalation phases to which different regions of Spain could progressively transition according to health indicato...
Source: Contact Lens and Anterior Eye - March 2, 2021 Category: Opthalmology Authors: Genis Cardona, Silvia Alonso, Anna Busquets Source Type: research

Dental disease detection on periapical radiographs based on deep convolutional neural networks
AbstractObjectivesIt is with a great prospect to develop an auxiliary diagnosis system for dental periapical radiographs based on deep convolutional neural networks (CNNs), and the indications and performances should be investigated. The aim of this study is to train CNNs for lesion detections on dental periapical radiographs, to evaluate performances across disease categories, severity levels, and train strategies.MethodsDeep CNNs with region proposal techniques were constructed for disease detections on clinical dental periapical radiographs, including decay, periapical periodontitis, and periodontitis, leveled as mild, ...
Source: International Journal of Computer Assisted Radiology and Surgery - March 2, 2021 Category: Intensive Care Source Type: research

IJERPH, Vol. 18, Pages 2434: Burnout of Healthcare Workers amid the COVID-19 Pandemic: A Japanese Cross-Sectional Survey
io Otsuka The coronavirus disease 2019 (COVID-19) global pandemic has drastically changed how we live and work. Amid the prolonged pandemic, burnout of the frontline healthcare professionals has become a significant concern. We conducted a cross-sectional survey study to provide data about the relationship between the COVID-19 pandemic and the prevalence of burnout in healthcare professionals in Japan. Healthcare workers in a single Japanese national university hospital participated in the survey, including basic demographics, whether a participant engaged in care of COVID-19 patients in the past 2 weeks and the Maslac...
Source: International Journal of Environmental Research and Public Health - March 2, 2021 Category: Environmental Health Authors: Yoshito Nishimura Tomoko Miyoshi Hideharu Hagiya Yoshinori Kosaki Fumio Otsuka Tags: Article Source Type: research

Severe acute respiratory syndrome coronavirus 2-induced acute aortic occlusion: a case report
We report a case of fatal acute aortic occlusion in a patient with coronavirus disease 2019.Case reportA 59-year-old Caucasian male with past medical history of peripheral vascular disease presented to the emergency department for evaluation of shortness of breath, fevers, and dry cough. His symptoms started 5 –7 days prior to the emergency department visit, and he received antibiotics in the outpatient setting without any effect. He was found to be febrile, tachypneic, and hypoxemic. He was placed on supplemental oxygen via a non-rebreather mask. Chest X-ray showed multifocal opacifications. Intravenou s antibiotics...
Source: Journal of Medical Case Reports - March 2, 2021 Category: General Medicine Source Type: research

The Effect of Maternal Voice on Venipuncture Induced Pain in Neonates: A Randomized Study
Venipuncture is a common procedure in the neonatal intensive care unit (NICU) and causes significant pain for neonates. (Source: Pain Management Nursing)
Source: Pain Management Nursing - March 2, 2021 Category: Nursing Authors: Yanjun Chen, Yang Li, Jing Sun, Dongren Han, Shuju Feng, Xin Zhang Tags: Original Article Source Type: research

Experiences of neonatal intensive care unit nurses as mothers of newborns in neonatal intensive care units: A Jordanian qualitative study
Little research has explored the experiences and perspectives of neonatal intensive care unit (NICU) nurses who have also experienced being NICU parents. The purpose of this study was to explore the experiences of these nurses who have or have ever had an infant hospitalized in a NICU. (Source: Journal of Pediatric Nursing)
Source: Journal of Pediatric Nursing - March 2, 2021 Category: Nursing Authors: Khulood Kayed Shattnawi, Intisar Hussein Abdallah, Wejdan Khater, Safa A. Alashram Source Type: research

Construction of a Risk Prediction Model for Subsequent Bloodstream Infection in Intestinal Carriers of Carbapenem-Resistant Enterobacteriaceae: A Retrospective Study in Hematology Department and Intensive Care Unit
(Source: Infection and Drug Resistance)
Source: Infection and Drug Resistance - March 1, 2021 Category: Infectious Diseases Tags: Infection and Drug Resistance Source Type: research

Cardiovascular disorders in patients infected with 2019  novel coronavirus
Ann Cardiol Angeiol (Paris). 2020 Nov 23:S0003-3928(20)30192-X. doi: 10.1016/j.ancard.2020.11.004. Online ahead of print.ABSTRACTThe coronavirus disease 2019 (COVID-19) outbreak has become a worldwide public health concern. Cardiovascular complications are relatively frequent, reaching 20% of COVID-19 patients and 43% of COVID-19 patients admitted in Intensive Care Unit. Cardiac injury mechanisms are multiple, including hyperinflammation, pro-coagulant and pro-thrombotic states, sepsis related cardiomyopathy, hypoxia in relation with lung severity, hemodynamic instability, cytokine storm, critically illness, direct myocard...
Source: Annales de Cardiologie et d'Angeiologie - March 1, 2021 Category: Cardiology Authors: V Aidan B Davido H Mustafic A Dinh N Mansencal A Fayssoil Source Type: research

Predictors of Intensive Care Unit Admission or Death in Patients with Coronavirus Disease 2019 Pneumonia in Istanbul, Turkey
Jpn J Infect Dis. 2021 Feb 26. doi: 10.7883/yoken.JJID.2020.1065. Online ahead of print.ABSTRACTWe aimed to determine the predictors of intensive care unit (ICU) admission or death in patients with Coronavirus Disease 2019 (COVID-19) pneumonia. This retrospective and single-center study includes patients aged ≥18 years who were diagnosed with COVID-19 pneumonia (laboratory and radiologically confirmed) between March 9 and April 8, 2020. Our composite endpoint was ICU admission or in-hospital death. To evaluate the factors in the composite endpoint, univariate and multivariate logistic regression analyses were performed....
Source: Japanese Journal of Infectious Diseases - March 1, 2021 Category: Infectious Diseases Authors: Serkan Surme Ahmet Buyukyazgan Osman Faruk Bayramlar Ayse Kurt Cinar Betul Copur Esra Zerdali Gulsah Tuncer Hatice Balli Inci Yilmaz Nakir Meltem Yazla Yesim Kurekci Filiz Pehlivanoglu Gonul Sengoz Source Type: research

Special care needs of very low birthweight preterm infants calculated from routine data: A 5-year analysis
Z Evid Fortbild Qual Gesundhwes. 2021 Feb 25:S1865-9217(21)00025-8. doi: 10.1016/j.zefq.2021.01.005. Online ahead of print.ABSTRACTBACKGROUND: The quality assurance directive for very low birthweight preterm infants (QFR-RL) by the German Federal Joint Committee calls for fixed nurse-to-patient ratios (NPRs) in neonatal intensive care, leading to considerable difficulties for staff planners, especially in smaller hospitals, as an extensive pool of nursing staff is required to ensure compliance with guidelines. Reliable parameters are therefore needed to provide a valid basis for staff planning.OBJECTIVE: To calculate the n...
Source: Zeitschrift fur Evidenz, Fortbildung und Qualitat im Gesundheitswesen - March 1, 2021 Category: Health Management Authors: Matthias Fr öhlich Daniel Kaup Frank F örster Bianka R ösner Christoph B ührer Source Type: research

Handgrip Force and Maximum Inspiratory and Expiratory Pressures in Critically Ill Patients With a Tracheostomy
Am J Crit Care. 2021 Mar 1;30(2):e48-e53. doi: 10.4037/ajcc2021248.ABSTRACTBACKGROUND: The association between peripheral striated muscle strength and respiratory muscle strength has been confirmed in a number of disorders. However, this association is unknown in intensive care unit patients with tracheostomies.OBJECTIVE: To examine correlations between handgrip force, maximum inspiratory pressure (MIP), and maximum expiratory pressure (MEP) in intensive care unit patients with tracheostomies.METHODS: Twenty patients (7 women, 13 men) with tracheostomies, in the intensive care unit longer than 11 days, in stable condition,...
Source: American Journal of Critical Care - March 1, 2021 Category: Nursing Authors: Konstantinos Grigoriadis Ioannis Efstathiou Zacharias Dimitriadis Georgia Konstantopoulou Anna Grigoriadou Georgios Vasileiadis Maria Micha Iraklis Tsagaris Apostolos Armaganidis Source Type: research

Rapid Mortality Review in the Intensive Care Unit: An In-Person, Multidisciplinary Improvement Initiative
Am J Crit Care. 2021 Mar 1;30(2):e32-e38. doi: 10.4037/ajcc2021829.ABSTRACTBACKGROUND: Significant resources have been allocated to decreasing the number of preventable deaths in hospitals, but identifying preventable factors and then leveraging them to effect system-wide change remains challenging.OBJECTIVE: To determine the ability of a novel in-person, multidisciplinary "rapid mortality review" process to identify deaths that are preventable and action items that lead to improvements in care.METHODS: Rapid mortality review sessions were conducted weekly for patients who died in the medical intensive care unit....
Source: American Journal of Critical Care - March 1, 2021 Category: Nursing Authors: Kristin E Schwab Wendy Simon Myrtle Yamamoto Anna Dermenchyan Xueqing Xu Yuhan Kao Alexander Zider Faisal Shaikh Bryan Garber Elinor Lee Zafia Anklesaria G Sofia Nelson Allison Ramsey Thanh H Neville Source Type: research

Daytime-to-Nighttime Sleep Ratios and Cognitive Impairment in Older Intensive Care Unit Survivors
CONCLUSIONS: The daytime-to-nighttime sleep ratio was abnormally high in the study population, revealing an altered sleep/wake cycle. Higher daytime-to-nighttime sleep ratios were associated with worse cognition, suggesting that proportionally greater daytime sleep may predict cognitive impairment.PMID:33644810 | DOI:10.4037/ajcc2021221 (Source: American Journal of Critical Care)
Source: American Journal of Critical Care - March 1, 2021 Category: Nursing Authors: Maya N El ías Cindy L Munro Zhan Liang Source Type: research

Predictive Validity of the Cubbin-Jackson and Braden Skin Risk Tools in Critical Care Patients: A Multisite Project
Am J Crit Care. 2021 Mar 1;30(2):140-144. doi: 10.4037/ajcc2021669.ABSTRACTBACKGROUND: Patients in intensive care units are 5 times more likely to have skin integrity issues develop than patients in other units. Identifying the most appropriate assessment tool may be critical to preventing pressure injuries in intensive care patients.OBJECTIVES: To validate the Cubbin-Jackson skin risk assessment in the critical care setting and to compare the predictive accuracy of the Cubbin-Jackson and Braden scales for the same patients.METHODS: In 5 intensive care units, the Cubbin-Jackson and Braden assessments were completed by diff...
Source: American Journal of Critical Care - March 1, 2021 Category: Nursing Authors: Jill M Delawder Samantha L Leontie Ralitsa S Maduro Merri K Morgan Kathie S Zimbro Source Type: research

Building Moral Resiliency Through the Nurse Education and Support Team Initiative
CONCLUSIONS: Pediatric intensive and progressive care nurses experience many challenges in their practice environments. The innovative NEST coach role enabled access to just-in-time support and guidance through morally and ethically challenging situations. As evidenced by the number of consultations and the positive staff response, intensive and progressive care nurses have embraced and integrated the NEST coach role into their culture and practice.PMID:33644802 | DOI:10.4037/ajcc2021534 (Source: American Journal of Critical Care)
Source: American Journal of Critical Care - March 1, 2021 Category: Nursing Authors: Michele DeGrazia Courtney Porter Anne Sheehan Stephanie Whitamore Deborah White Penny Winter Nuttall Tyler Blanchard Norah Davis Jennifer Steadman Patricia Hickey Source Type: research

Nurses' Perceptions of Telemedicine Adoption in the Intensive Care Unit
CONCLUSIONS: Despite differences in nurses' years of experience, the perceptions of the Emory e-ICU Center did not differ significantly among nurses.PMID:33644799 | DOI:10.4037/ajcc2021205 (Source: American Journal of Critical Care)
Source: American Journal of Critical Care - March 1, 2021 Category: Nursing Authors: Roberta Kaplow Mary Zellinger Source Type: research

Tonsillitis, tonsillectomy, and deep neck space infections in England: the case for a new guideline for surgical and non-surgical management
DISCUSSION: The rise in admissions for tonsillitis and its complications appears to correspond closely to the date of SIGN guidance and clinical commissioning group rationing of tonsillectomy and is on the background of a rise in the population of the UK. The move towards daycase tonsillectomy has reduced bed occupancy after surgery but this has been counteracted by an increase in admissions for tonsillitis and deep neck space infections, sometimes requiring lengthy intensive care stays and a protracted course of rehabilitation. The total cost of treating the complications of tonsillitis in England in 2017 is estimated to ...
Source: Annals of the Royal College of Surgeons of England - March 1, 2021 Category: Surgery Authors: M Pankhania J Rees A Thompson S Richards Source Type: research

Medical training in acute specialties: the acute care common stem training pathway
Br J Hosp Med (Lond). 2021 Feb 2;82(2):1-5. doi: 10.12968/hmed.2020.0634. Epub 2021 Feb 3.ABSTRACTIn 2007, the acute care common stem pathway changed the delivery of acute specialty training. Acute care common stem is the core training programme for all emergency medicine trainees, 46% of anaesthetic trainees and a cohort of acute medicine trainees with more than 630 places nationally, the third highest of any core training programme. In their first 2 years of core training (CT1-2), trainees rotate through 6-month rotations in emergency medicine, acute medicine, anaesthetics and intensive care to gain core competencies in ...
Source: British Journal of Hospital Medicine - March 1, 2021 Category: Internal Medicine Authors: Benjamin Stretch Agnieszka Jakubowska Mihir Patel Matthew Waite Allan Xu Source Type: research

What Is Pulmonary Hypertension?
Am J Respir Crit Care Med. 2021 Mar 1;203(5):P12-P13. doi: 10.1164/rccm.2035P12.NO ABSTRACTPMID:33646084 | DOI:10.1164/rccm.2035P12 (Source: Am J Respir Crit Car...)
Source: Am J Respir Crit Car... - March 1, 2021 Category: Intensive Care Authors: Marianna Sockrider Source Type: research

List of Reviewers-2020
Am J Respir Crit Care Med. 2021 Mar 1;203(5):652-661. doi: 10.1164/rccm.2035reviewers.NO ABSTRACTPMID:33646083 | DOI:10.1164/rccm.2035reviewers (Source: Am J Respir Crit Car...)
Source: Am J Respir Crit Car... - March 1, 2021 Category: Intensive Care Source Type: research

Off-label drug use and the risk of medication errors in critically ill neonates: A conceptual pilot study
CONCLUSION: Significant proportions of critically ill neonates received at least one OLD/unlicensed drug and such use was associated with potentially increased risk of medication errors.PMID:33646182 | DOI:10.3233/JRS-200058 (Source: International Journal of Risk and Safety in Medicine)
Source: International Journal of Risk and Safety in Medicine - March 1, 2021 Category: Drugs & Pharmacology Authors: Kannan Sridharan Muna Al Jufairi Eman Al Ansari Source Type: research

The prediction value of Glasgow coma scale-pupils score in neurocritical patients: a retrospective study
CONCLUSIONS: GCP-P discriminated well in between death in neurocritical patients. GCP-P improved predictive performance for short-term mortality over GCS and its derivatives in neurocritical patients. It would be a simple, early and reasonable daily routine option for prognosis assessment in neurocritical setting.PMID:33645359 | DOI:10.1080/02699052.2021.1890821 (Source: Brain Injury)
Source: Brain Injury - March 1, 2021 Category: Neurology Authors: Yingxin Lin Sheng Zhang Weixing Zhang Xinxin Wang Lei Huang Hua Luo Source Type: research

Clinical features and outcomes of hospitalized COVID-19 patients in a low burden region
Pathog Glob Health. 2021 Feb 28:1-7. doi: 10.1080/20477724.2021.1893485. Online ahead of print.ABSTRACTData on the clinical features and outcomes of COVID-19 patients from countries with low disease burden are rare. Greece, however, presented a low burden of COVID-19 disease during the first pandemic outbreak. This is a retrospective study of COVID-19 hospitalized patients in Greece. Clinical data were extracted from medical records using univariable and multivariable logistic regression analyses to assess the factors associated with Intensive Care Unit (ICU) admission and in-hospital death. Eighty-five patients were inclu...
Source: Pathogens and Global Health - March 1, 2021 Category: International Medicine & Public Health Authors: Mylona Eleni Margellou Evangelia Kranidioti Eleftheria Vlachakos Vasilios Sypsa Vana Sakka Vissaria Balis Evangelos Kalomenidis Ioannis Source Type: research

Comments on the updated German S3 guidelines on intravascular volume therapy in adults
Anaesthesist. 2021 Mar 1. doi: 10.1007/s00101-021-00929-4. Online ahead of print.ABSTRACTThe German S3 guidelines on intravascular volume therapy in adults were updated in September 2020. Based on updated evidence recommendations for the diagnosis of isotonic dehydration and for fluid therapy with crystalloids and colloids in peri-interventional and intensive care medicine were proposed.PMID:33646330 | DOI:10.1007/s00101-021-00929-4 (Source: Der Anaesthesist)
Source: Der Anaesthesist - March 1, 2021 Category: Anesthesiology Authors: Emmanuel Schneck Michael Sander Bernd Saugel Daniel A Reuter Marit Habicher Source Type: research

The Relationship Between Asthma, Eosinophilia, and Outcomes in COVID-19 Infection
Ann Allergy Asthma Immunol. 2021 Feb 26:S1081-1206(21)00139-3. doi: 10.1016/j.anai.2021.02.021. Online ahead of print.ABSTRACTBACKGROUND: The impact of asthma diagnosis and asthma endotype on outcomes from COVID-19 infection remains unclear.OBJECTIVE: To describe the association between asthma diagnosis and endotype and clinical outcomes among patients diagnosed with COVID-19 infection.METHODS: Retrospective multicenter cohort study of outpatients and inpatients presenting to six hospitals in the Mount Sinai Health System New York metropolitan region between March 7 th to June 7 th , 2020, with COVID-19 infection, with and...
Source: Annals of Allergy, Asthma and Immunology - March 1, 2021 Category: Allergy & Immunology Authors: Kam Sing Ho Daniel Howell Linda Rogers Bharat Narasimhan Hannah Verma David Steiger Source Type: research

Cardiovascular disorders in patients infected with 2019  novel coronavirus
Ann Cardiol Angeiol (Paris). 2020 Nov 23:S0003-3928(20)30192-X. doi: 10.1016/j.ancard.2020.11.004. Online ahead of print.ABSTRACTThe coronavirus disease 2019 (COVID-19) outbreak has become a worldwide public health concern. Cardiovascular complications are relatively frequent, reaching 20% of COVID-19 patients and 43% of COVID-19 patients admitted in Intensive Care Unit. Cardiac injury mechanisms are multiple, including hyperinflammation, pro-coagulant and pro-thrombotic states, sepsis related cardiomyopathy, hypoxia in relation with lung severity, hemodynamic instability, cytokine storm, critically illness, direct myocard...
Source: Annales de Cardiologie et d'Angeiologie - March 1, 2021 Category: Cardiology Authors: V Aidan B Davido H Mustafic A Dinh N Mansencal A Fayssoil Source Type: research

Risk Factors for Emergency Room and Hospital Care Among Patients With Solid Tumors on Immune Checkpoint Inhibitor Therapy
Conclusions: Understanding demographic and clinical risk factors for ER/IP care among patients on ICIs can help highlight disparities, prospectively identify high-risk patients, and inform preventive programs aimed at reducing such care. (Source: American Journal of Clinical Oncology)
Source: American Journal of Clinical Oncology - March 1, 2021 Category: Cancer & Oncology Tags: Original Articles: Immunotherapy Source Type: research

Anesthesiologists’ and Intensive Care Providers’ Exposure to Coronavirus Disease 2019 Infection in a New York City Academic Center: A Prospective Cohort Study Assessing Symptoms and Coronavirus Disease 2019 Antibody Testing
(Anesth Analg. 2020;131:669–676) (Source: Obstetric Anesthesia Digest)
Source: Obstetric Anesthesia Digest - March 1, 2021 Category: Anesthesiology Tags: Epidemiologic Reports Surveys Source Type: research

Role of Damage-Associated Molecular Patterns in Septic Acute Kidney Injury, From Injury to Recovery
Damage-associated molecular patterns (DAMPs) are a group of immunostimulatory molecules, which take part in inflammatory response after tissue injury. Kidney-specific DAMPs include Tamm-Horsfall glycoprotein, crystals, and uromodulin, released by tubular damage for example. Non-kidney-specific DAMPs include intracellular particles such as nucleus [histones, high-mobility group box 1 protein (HMGB1)] and cytosol parts. DAMPs trigger innate immunity by activating the NRLP3 inflammasome, G-protein coupled class receptors or the Toll-like receptor. Tubular necrosis leads to acute kidney injury (AKI) in either septic, ischemic ...
Source: Frontiers in Immunology - March 1, 2021 Category: Allergy & Immunology Source Type: research

Lung ultrasound presentation of COVID-19 patients: phenotypes and correlations
AbstractBedside lung ultrasound (LUS) can play a role in the setting of the SarsCoV2 pneumonia pandemic. To evaluate the clinical and LUS features of COVID-19 in the ED and their potential prognostic role, a cohort of laboratory-confirmed COVID-19 patients underwent LUS upon admission in the ED. LUS score was derived from 12 fields. A prevalent LUS pattern was assigned depending on the presence of interstitial syndrome only (Interstitial Pattern), or evidence of subpleural consolidations in at least two fields (Consolidation Pattern). The endpoint was 30-day mortality. The relationship between hemogasanalysis parameters an...
Source: Internal and Emergency Medicine - March 1, 2021 Category: Emergency Medicine Source Type: research

The Role of Self-compassion, Concern for Others, and Basic Psychological Needs in the Reduction of Caregiving Burnout
ConclusionsOur study highlights compassion and self-compassion as potential resilience factors against the challenge of burnout in healthcare. It points to promising avenues for preemptive clinical interventions. (Source: Mindfulness)
Source: Mindfulness - March 1, 2021 Category: Psychiatry & Psychology Source Type: research

Distinct pattern of microsusceptibility changes on brain magnetic resonance imaging (MRI) in critically ill patients on mechanical ventilation/oxygenation
ConclusionWe showed distinct patterns of diffuse brain SWI susceptibilities in critically-ill patients who underwent mechanical ventilation/ECMO. The etiology of these foci remains uncertain, but the association with mechanical ventilation, prolonged respiratory failure, and hypoxemia seems probable explanations. (Source: Neuroradiology)
Source: Neuroradiology - March 1, 2021 Category: Radiology Source Type: research

The surviving sepsis campaign: fluid resuscitation and vasopressor therapy research priorities in adult patients
To expand upon the priorities of fluid resuscitation and vasopressor therapy research priorities identified by a group of experts assigned by the Society of Critical Care Medicine and the European Society of I... (Source: Intensive Care Medicine Experimental)
Source: Intensive Care Medicine Experimental - March 1, 2021 Category: Surgery Authors: Ishaq Lat, Craig M. Coopersmith, Daniel De Backer and Craig M. Coopersmith Tags: Review Source Type: research

COVID-19 research in critical care: the good, the bad, and the ugly
(Source: Intensive Care Medicine)
Source: Intensive Care Medicine - March 1, 2021 Category: Intensive Care Source Type: research

MRI-based radiomic feature analysis of end-stage liver disease for severity stratification
ConclusionsWe demonstrated that MRI-based radiomic features of the liver and spleen have the potential to predict the severity of liver cirrhosis, using decompensation or MELD status as imperfect surrogate measures for disease severity. (Source: International Journal of Computer Assisted Radiology and Surgery)
Source: International Journal of Computer Assisted Radiology and Surgery - March 1, 2021 Category: Intensive Care Source Type: research

End-tidal capnography monitoring in infants ventilated on the neonatal intensive care unit
Journal of Perinatology, Published online: 01 March 2021; doi:10.1038/s41372-021-00978-yEnd-tidal capnography monitoring in infants ventilated on the neonatal intensive care unit (Source: Journal of Perinatology)
Source: Journal of Perinatology - March 1, 2021 Category: Perinatology & Neonatology Authors: Emma Williams Theodore Dassios Niamh O ’Reilly Alison Walsh Anne Greenough Source Type: research

Revisiting the definition of bronchopulmonary dysplasia in premature infants at a single center quaternary neonatal intensive care unit
Journal of Perinatology, Published online: 01 March 2021; doi:10.1038/s41372-021-00980-4Revisiting the definition of bronchopulmonary dysplasia in premature infants at a single center quaternary neonatal intensive care unit (Source: Journal of Perinatology)
Source: Journal of Perinatology - March 1, 2021 Category: Perinatology & Neonatology Authors: Faith Kim David A. Bateman Nimrod Goldshtrom Rakesh Sahni Jen Tien Wung Aaron Wallman-Stokes Source Type: research

Predicting readmission to intensive care after cardiac surgery within index hospitalization: A systematic review
The objective of this systematic review was to identify risk factors and clinical prediction models for readmission within a single hospitalization to intensive care after cardiac surgery. PubMed, MEDLINE and EMBASE databases were searched to identify candidate articles. (Source: Journal of Cardiothoracic and Vascular Anesthesia)
Source: Journal of Cardiothoracic and Vascular Anesthesia - March 1, 2021 Category: Anesthesiology Authors: Miss. Linda Kimani, Dr. Samuel Howitt, Miss. Charlene Tennyson, Dr. Richard Templeton, Professor. Charles McCollum, Mr. Stuart W. Grant Tags: Regular review Source Type: research

Major bleeding complications in critically ill patients with COVID-19 pneumonia
AbstractAs patients with COVID-19 pneumonia admitted to intensive care unit (ICU) have high rates of thrombosis, high doses of thromboprophylaxis have been proposed. The associated bleeding risk remains unknown. We investigated major bleeding complications in ICU COVID-19 patients and we examined their relationship with inflammation and thromboprophylaxis. Retrospective monocentric study of consecutive adult patients admitted in ICU for COVID-19 pneumonia requiring mechanical ventilation. Data collected included demographics, anticoagulation status, coagulation tests and outcomes including major bleeding and thrombotic eve...
Source: Journal of Thrombosis and Thrombolysis - March 1, 2021 Category: Hematology Source Type: research

A COVID-19 pregnant patient with thrombotic thrombocytopenic purpura: a case report
ConclusionThis viral infection caused fever and dyspnea, and the patient was tested positive for COVID-19 infection. A chest computed tomography scan showed diffuse multiple bilateral consolidations and interlobar septal thickening. She stayed at the Intensive Care Unit for 20  days and treated with plasmapheresis. As far as we know, this is the first report of a TTP pregnant patient with COVID-19 infection. (Source: Journal of Medical Case Reports)
Source: Journal of Medical Case Reports - March 1, 2021 Category: General Medicine Source Type: research

No Visitors Allowed
This essay describes the author ’s experience of not being able to visit and advocate for her mother in the intensive care unit during the coronavirus disease 2019 pandemic. (Source: JAMA Neurology)
Source: JAMA Neurology - March 1, 2021 Category: Neurology Source Type: research

Annual prevalence, characteristics, and outcomes of intensive care patients with skin or soft tissue infections in Australia and New Zealand: A retrospective cohort study between 2006-2017
This study intended to describe the annual prevalence, characteristics, and outcomes of critically ill adult patients admitted to the ICU for an SSTI. (Source: Australian Critical Care)
Source: Australian Critical Care - March 1, 2021 Category: Nursing Authors: Marjolein A. Bekker, Sumeet Rai, M. Sesmu Arbous, Ekavi N. Georgousopoulou, David V. Pilcher, Frank M.P. van Haren Tags: Research paper Source Type: research