Effective operating room (OR) utilization by performing low-complex surgical procedures during the 2020 corona pandemic
AbstractPurposeThe SARS-CoV-2 pandemic has almost stopped all elective surgical treatment throughout the world. As operating room (OR) capacities are reduced everywhere to ensure availability of intensive care capacities, especially low-complex surgical procedures are often postponed. These include totally implantable central-venous access ports which are important for the oncologic treatment of cancer patients.MethodsIn our study, we investigated the potential of an outpatient surgical centre (OSC) in terms of workflow effectiveness compared to the central operating room complex (COR) of a university hospital using low-co...
Source: International Journal of Computer Assisted Radiology and Surgery - May 17, 2021 Category: Intensive Care Source Type: research

Severity of hypoxemia may explain indeterminate results in pediatric trials of inhaled nitric oxide
(Source: Intensive Care Medicine)
Source: Intensive Care Medicine - May 16, 2021 Category: Intensive Care Source Type: research

Tattoo tomography: Freehand 3D photoacoustic image reconstruction with an optical pattern
ConclusionsIn contrast to previous approaches to 3D ultrasound (US) or PAT reconstruction, theTattoo approach neither requires complex external hardware nor training data acquired for a specific application. It could thus become a valuable tool for clinical freehand PAT. (Source: International Journal of Computer Assisted Radiology and Surgery)
Source: International Journal of Computer Assisted Radiology and Surgery - May 16, 2021 Category: Intensive Care Source Type: research

Incidence and microbiological characteristics of neonatal late onset sepsis in a Neonatal Intensive Care Unit in Peru
(Source: International Journal of Infectious Diseases)
Source: International Journal of Infectious Diseases - May 15, 2021 Category: Infectious Diseases Authors: Cecilia Herbozo, Irene Julca, Fiorella Flores, Roger Hernandez, Jaime Zegarra Source Type: research

Pulmonary hypertension in late onset neonatal sepsis using functional echocardiography: a prospective study
This study was aimed to measure the pulmonary artery systolic pressure (PASP) in neonates with late onset sepsis (LOS) and to estimate the proportion of PH in neonatal sepsis using functional echocardiography (FnECHO).MethodsThis prospective observational study was conducted at a tertiary neonatal intensive care unit (NICU). All neonates admitted in the NICU with suspected LOS underwent FnECHO within 6 hours of onset of clinical signs and PASP was recorded. Pulmonary hypertension was defined as PASP of  >  35 mmHg. PASP of neonates with positive culture results (proven LOS) was compared with that of g...
Source: Journal of Ultrasound - May 15, 2021 Category: Radiology Source Type: research

Inter-regional transfers for pandemic surges were associated with reduced mortality rates
(Source: Intensive Care Medicine)
Source: Intensive Care Medicine - May 15, 2021 Category: Intensive Care Source Type: research

IJCARS —IPCAI 2021 Special Issue: Information Processing for Computer-Assisted Interventions, 12th International Conference 2021—Part 1
(Source: International Journal of Computer Assisted Radiology and Surgery)
Source: International Journal of Computer Assisted Radiology and Surgery - May 15, 2021 Category: Intensive Care Source Type: research

Autonomous pick-and-place using the dVRK
ConclusionProcedural automation can be an important workflow enhancement functionality in future robotic surgery systems. We have shown a preliminary study on semi-autonomous US imaging, and this could support more efficient data acquisition. (Source: International Journal of Computer Assisted Radiology and Surgery)
Source: International Journal of Computer Assisted Radiology and Surgery - May 15, 2021 Category: Intensive Care Source Type: research

Impact of Contrast Echocardiography on Outcomes in Critically Ill Patients
Limited data suggests ultrasound enhancing agent (UEA) use is associated with changes in clinical management and lower mortality in intensive care unit (ICU) patients. We conducted a retrospective observational study to determine if contrast echocardiography (vs non-contrast echocardiography) is associated with differences in length of stay (LOS) and subsequent resource utilization in the ICU setting. The Premier Healthcare Database (Charlotte, NC) was analyzed to identify patients receiving Definity vs. (Source: The American Journal of Cardiology)
Source: The American Journal of Cardiology - May 15, 2021 Category: Cardiology Authors: Michael L. Main, Julia Weleski Fu, Jake Gundrum, Nancy Allen LaPointe, Linda D. Gillam, Sharon L. Mulvagh Source Type: research

Electrolyte monitoring during regional citrate anticoagulation in continuous renal replacement therapy
AbstractPatients with acute kidney injury who need continuous renal replacement therapy with locoregional citrate anticoagulation are at risk of citrate accumulation with disruption of the calcium balance. We aimed to evaluate the safety of detecting citrate accumulation and adjusting electrolyte disbalances during continuous venovenous hemodialysis (CVVHD) in critically ill patients with acute kidney injury using a blood sample frequency every 6 h. A prospective single center study in critically ill intensive care unit patients who suffered from acute kidney injury with the need of renal replacement therapy. We evaluated ...
Source: Journal of Clinical Monitoring and Computing - May 15, 2021 Category: Information Technology Source Type: research

A Retrospective Observational Cohort Study: Epidemiology and Outcomes of Pediatric Unintentional Falls in US Emergency Departments
The leading cause of nonfatal US emergency department (ED) visits for unintentional injuries among children ages 0-17 years was falls (2001-2017).[1] Falls were more common among boys and children ages 0-4 years, with the mechanism of fall varied depending on the age.[2] In Utah, the most common type of preventable injury leading to pediatric intensive care unit (PICU) admissions was also falls.[3] Falls have been associated with pediatric brain injuries, often influenced by age, race, and sex.[4] Between 2006-2010, child falls accounted for 11,535 head injuries, costing a projected billion dollars nationally. (Source: Injury)
Source: Injury - May 15, 2021 Category: Orthopaedics Authors: Quynh-Uyen P. Nguyen, Olga Saynina, Elizabeth A. Pirrotta, Lynne C. Huffman, Nancy Ewen Wang Source Type: research

From the Editor ’s Desk…
It has not been well established if patients with autoimmune hepatitis (AIH) treated with immunosuppressive drugs are at higher risk of severe COVID-19 infection. The current study by Marjot and coworkers reports the course of SARS CoV-2 infection in 70 patients with AIH on immunosuppressive therapy and compares it with that of 862 patients with non-AIH chronic liver disease (CLD), all from 3 international large-scale reporting registries, and also with 769 consecutive non-CLD controls. There were no differences between AIH and non-AIH CLD patients for rate of hospitalisation, intensive care unit requirement, invasive vent...
Source: Journal of Hepatology - May 14, 2021 Category: Gastroenterology Authors: Patrizia Burra, Frank Tacke, Vlad Ratziu, Stefan Zeuzem, Bruno Sangro, Paolo Angeli Tags: From the Editor's Desk Source Type: research

Effect of a Multistage Educational Skill-Based Program on Nurse's Stress and Anxiety in the Intensive Care Setting: A Randomized Controlled Trial
CONCLUSIONS: To improve the mental health and performance of the intensive care unit nurses, knowledge-based and skill-based training programs seem useful. Continuous training may help to maintain the effectiveness of these programs over time.PMID:33986878 | PMC:PMC8093071 | DOI:10.1155/2021/8811347 (Source: Behavioural Neurology)
Source: Behavioural Neurology - May 14, 2021 Category: Neurology Authors: Mohsen Saffari Farshid Rahimi Bashar Amir Vahedian-Azimi Mohamad Amin Pourhoseingholi Leila Karimi Morteza Shamsizadeh Keivan Gohari-Moghadam Amirhossein Sahebkar Source Type: research

Clinical Presentation and Management of Severe Acute Renal Failure in McArdle Disease
We present a rare case of a Caucasian male, aged 26-years, who developed rhabdomyolysis-induced acute renal failure and uremic encephalopathy. Neurological examination and histopathological studies supported the diagnosis of McArdle disease. The severity of his symptoms necessitated urgent hemodialysis, upon which the patient reported improvement in status. Acute renal failure in McArdle disease usually resolves with supportive treatment and maintenance of regular physical activity. Nevertheless, in more severe cases, intensive care with urgent hemodialysis may be needed. A multidisciplinary approach is necessary for the a...
Source: Clinical Medicine and Research - May 14, 2021 Category: General Medicine Authors: Majdi Hamadeh Khalil Nasrallah Zeinab Ajami Rahil Zeaiter Layan Abbas Samih Hamadeh Jawad Fares Source Type: research

Clinical Presentation and Management of Severe Acute Renal Failure in McArdle Disease
We present a rare case of a Caucasian male, aged 26-years, who developed rhabdomyolysis-induced acute renal failure and uremic encephalopathy. Neurological examination and histopathological studies supported the diagnosis of McArdle disease. The severity of his symptoms necessitated urgent hemodialysis, upon which the patient reported improvement in status. Acute renal failure in McArdle disease usually resolves with supportive treatment and maintenance of regular physical activity. Nevertheless, in more severe cases, intensive care with urgent hemodialysis may be needed. A multidisciplinary approach is necessary for the a...
Source: Clin Med Res - May 14, 2021 Category: Research Authors: Majdi Hamadeh Khalil Nasrallah Zeinab Ajami Rahil Zeaiter Layan Abbas Samih Hamadeh Jawad Fares Source Type: research

Mechanistic Insights into Cell-free Hemoglobin-induced Injury During Septic Shock
CONCLUSIONS: In the absence and presence of infection, CFH infusions resulted in pulmonary hypertension, cardiogenic shock and multi-organ failure, likely through NO scavenging. In the presence of infection alone, CFH infusions worsened oxygen exchange and lung injury, presumably by supplying iron that promoted bacterial growth. CFH elevation, a known consequence of clinical septic shock, adversely impacts sepsis outcomes through more than one mechanism and is a biologically plausible, non-antibiotic, non-cytokine target for therapeutic intervention.PMID:33989079 | DOI:10.1152/ajpheart.00092.2021 (Source: American Journal ...
Source: American Journal of Physiology. Heart and Circulatory Physiology - May 14, 2021 Category: Physiology Authors: Jeffrey Wang Willard N Applefeld Junfeng Sun Steven B Solomon Jing Feng Zoe G Couse Thomas F Risoleo Robert L Danner Jes ús Tejero Juan Lertora Elmira Alipour Swati Basu Vandana Sachdev Daniel B Kim-Shapiro Mark T Gladwin Harvey G Klein Charles Natanson Source Type: research

The ongoing impact of COVID-19 on adult cardiac surgery and suggestions for safe continuation throughout the pandemic: a review of expert opinions
CONCLUSIONS: This paper suggests a 'CARDIO' approach for reintroducing elective procedures: 'Care, Assess, Re-Evaluate, Develop, Implement, Overcome'; prioritising the mental and physical health of the workforce, learning from and sharing experiences and objectively prioritising patients to improve case load.PMID:33985387 | DOI:10.1177/02676591211013730 (Source: Perfusion)
Source: Perfusion - May 14, 2021 Category: Cardiovascular & Thoracic Surgery Authors: Kirstie Kirkley Umberto Benedetto Massimo Caputo Gianni D Angelini Hunaid A Vohra Source Type: research

Utility of inflammatory biomarkers in patients with COVID-19 infections: Bahrain experience
Conclusion: We observed serum ferritin, D-dimer and CRP to accurately predict patients developing severe COVID-19 infections as well as those at risk of developing COVID pneumonia. A trend in IL-6 levels was observed in patients on tocilizumab therapy.PMID:33988463 | DOI:10.2217/bmm-2020-0422 (Source: Future Medicine: Biomarkers in Medicine)
Source: Future Medicine: Biomarkers in Medicine - May 14, 2021 Category: Internal Medicine Authors: Eman Farid Kannan Sridharan Ola Am Alsegai Safa Al Khawaja Eman J Mansoor Noor A Teraifi Manaf Al Qahtani Jameela Al Salman Source Type: research

The relationship between serum lactate dehydrogenase level and mortality in critically ill patients
Conclusion: The serum LDH level may aid in the early identification of mortality risk in critically ill patients.PMID:33988459 | DOI:10.2217/bmm-2020-0671 (Source: Future Medicine: Biomarkers in Medicine)
Source: Future Medicine: Biomarkers in Medicine - May 14, 2021 Category: Internal Medicine Authors: Dan Su Jiamei Li Jiajia Ren Ya Gao Ruohan Li Xuting Jin Jingjing Zhang Gang Wang Source Type: research

The Use of Dornase Alfa in the Management of COVID-19-Associated Adult Respiratory Distress Syndrome
CONCLUSIONS: Administration of inhalational dornase alfa via a filtered nebulizer medication system or through an adapter in a ventilator circuit should be considered in all COVID-19-positive patients with ARDS as early in the disease course as possible.PMID:33986957 | PMC:PMC8074548 | DOI:10.1155/2021/8881115 (Source: Critical Care Research and Practice)
Source: Critical Care Research and Practice - May 14, 2021 Category: Intensive Care Authors: Andrew Toma Christina Darwish Michele Taylor Justin Harlacher Ribal Darwish Source Type: research

Maternal Intensive Care Unit Admission as an Indicator of Severe Acute Maternal Morbidity: A Population-Based Study
CONCLUSIONS: Among women with SAMM, 1 in 5 is admitted to an ICU; 15.5% of those admitted in ICU have no other SAMM criterion and a less acute condition. These results challenge the use of ICU admission as a criterion of SAMM.PMID:33989204 | DOI:10.1213/ANE.0000000000005578 (Source: Anesthesia and Analgesia)
Source: Anesthesia and Analgesia - May 14, 2021 Category: Anesthesiology Authors: Charlotte Godeberge Catherine Deneux-Tharaux Aur élien Seco Mathias Rossignol Anne Alice Chantry Marie-Pierre Bonnet EPIMOMS Study Group Source Type: research

Adjunctive homeopathic treatment of hospitalized COVID-19 patients (COVIHOM): A retrospective case series
CONCLUSION: The observations suggest that adjunctive homeopathic treatment may be helpful to treat patients with confirmed COVID-19 even in high - risk patients especially since there is no conventional treatment of COVID-19 available at present.PMID:33989861 | DOI:10.1016/j.ctcp.2021.101415 (Source: Complementary Therapies in Clinical Practice)
Source: Complementary Therapies in Clinical Practice - May 14, 2021 Category: Complementary Medicine Authors: Takacs Michael Frass Michael Walder Gernot Fibert Philippa Rottensteiner Maria Gl ück Walter Lechleitner Peter Oberbaum Menachem Leisser Ilse Chandak Kavita Panhofer Peter Weiermayer Petra Source Type: research

Effect of a Multistage Educational Skill-Based Program on Nurse's Stress and Anxiety in the Intensive Care Setting: A Randomized Controlled Trial
CONCLUSIONS: To improve the mental health and performance of the intensive care unit nurses, knowledge-based and skill-based training programs seem useful. Continuous training may help to maintain the effectiveness of these programs over time.PMID:33986878 | PMC:PMC8093071 | DOI:10.1155/2021/8811347 (Source: Behavioural Neurology)
Source: Behavioural Neurology - May 14, 2021 Category: Neurology Authors: Mohsen Saffari Farshid Rahimi Bashar Amir Vahedian-Azimi Mohamad Amin Pourhoseingholi Leila Karimi Morteza Shamsizadeh Keivan Gohari-Moghadam Amirhossein Sahebkar Source Type: research

Clinical Presentation and Management of Severe Acute Renal Failure in McArdle Disease
We present a rare case of a Caucasian male, aged 26-years, who developed rhabdomyolysis-induced acute renal failure and uremic encephalopathy. Neurological examination and histopathological studies supported the diagnosis of McArdle disease. The severity of his symptoms necessitated urgent hemodialysis, upon which the patient reported improvement in status. Acute renal failure in McArdle disease usually resolves with supportive treatment and maintenance of regular physical activity. Nevertheless, in more severe cases, intensive care with urgent hemodialysis may be needed. A multidisciplinary approach is necessary for the a...
Source: Clinical Medicine and Research - May 14, 2021 Category: General Medicine Authors: Majdi Hamadeh Khalil Nasrallah Zeinab Ajami Rahil Zeaiter Layan Abbas Samih Hamadeh Jawad Fares Source Type: research

Clinical Presentation and Management of Severe Acute Renal Failure in McArdle Disease
We present a rare case of a Caucasian male, aged 26-years, who developed rhabdomyolysis-induced acute renal failure and uremic encephalopathy. Neurological examination and histopathological studies supported the diagnosis of McArdle disease. The severity of his symptoms necessitated urgent hemodialysis, upon which the patient reported improvement in status. Acute renal failure in McArdle disease usually resolves with supportive treatment and maintenance of regular physical activity. Nevertheless, in more severe cases, intensive care with urgent hemodialysis may be needed. A multidisciplinary approach is necessary for the a...
Source: Clin Med Res - May 14, 2021 Category: Research Authors: Majdi Hamadeh Khalil Nasrallah Zeinab Ajami Rahil Zeaiter Layan Abbas Samih Hamadeh Jawad Fares Source Type: research

Mechanistic Insights into Cell-free Hemoglobin-induced Injury During Septic Shock
CONCLUSIONS: In the absence and presence of infection, CFH infusions resulted in pulmonary hypertension, cardiogenic shock and multi-organ failure, likely through NO scavenging. In the presence of infection alone, CFH infusions worsened oxygen exchange and lung injury, presumably by supplying iron that promoted bacterial growth. CFH elevation, a known consequence of clinical septic shock, adversely impacts sepsis outcomes through more than one mechanism and is a biologically plausible, non-antibiotic, non-cytokine target for therapeutic intervention.PMID:33989079 | DOI:10.1152/ajpheart.00092.2021 (Source: American Journal ...
Source: American Journal of Physiology. Heart and Circulatory Physiology - May 14, 2021 Category: Physiology Authors: Jeffrey Wang Willard N Applefeld Junfeng Sun Steven B Solomon Jing Feng Zoe G Couse Thomas F Risoleo Robert L Danner Jes ús Tejero Juan Lertora Elmira Alipour Swati Basu Vandana Sachdev Daniel B Kim-Shapiro Mark T Gladwin Harvey G Klein Charles Natanson Source Type: research

The ongoing impact of COVID-19 on adult cardiac surgery and suggestions for safe continuation throughout the pandemic: a review of expert opinions
CONCLUSIONS: This paper suggests a 'CARDIO' approach for reintroducing elective procedures: 'Care, Assess, Re-Evaluate, Develop, Implement, Overcome'; prioritising the mental and physical health of the workforce, learning from and sharing experiences and objectively prioritising patients to improve case load.PMID:33985387 | DOI:10.1177/02676591211013730 (Source: Perfusion)
Source: Perfusion - May 14, 2021 Category: Cardiovascular & Thoracic Surgery Authors: Kirstie Kirkley Umberto Benedetto Massimo Caputo Gianni D Angelini Hunaid A Vohra Source Type: research

The Use of Dornase Alfa in the Management of COVID-19-Associated Adult Respiratory Distress Syndrome
CONCLUSIONS: Administration of inhalational dornase alfa via a filtered nebulizer medication system or through an adapter in a ventilator circuit should be considered in all COVID-19-positive patients with ARDS as early in the disease course as possible.PMID:33986957 | PMC:PMC8074548 | DOI:10.1155/2021/8881115 (Source: Critical Care Research and Practice)
Source: Critical Care Research and Practice - May 14, 2021 Category: Intensive Care Authors: Andrew Toma Christina Darwish Michele Taylor Justin Harlacher Ribal Darwish Source Type: research

Determinants of healthcare worker turnover in intensive care units: A micro-macro multilevel analysis
ConclusionsThe findings of this research may help decision makers within hospitals by highlighting major determinants of turnover among RANs. In addition, the new approach proposed here could prove useful to researchers faced with similar micro-macro data. (Source: PLoS One)
Source: PLoS One - May 14, 2021 Category: Biomedical Science Authors: Oumou Salama Daouda Source Type: research

Treatment of positive urine cultures in the neonatal intensive care unit: a guideline to reduce antibiotic utilization
Journal of Perinatology, Published online: 14 May 2021; doi:10.1038/s41372-021-01079-6Treatment of positive urine cultures in the neonatal intensive care unit: a guideline to reduce antibiotic utilization (Source: Journal of Perinatology)
Source: Journal of Perinatology - May 14, 2021 Category: Perinatology & Neonatology Authors: Daniel P. Gorski Adam S. Bauer Nina S. Menda Matthew W. Harer Source Type: research

Use of Vasopressors in Extremely Preterm Infants in First Week of Life
Am J Perinatol DOI: 10.1055/s-0041-1729558 Objective A significant variability exists for diagnosis and treatment of hypotension in extremely preterm infants. Benefits of the use of vasopressors remain unclear. We wanted to identify the risk factors associated with use of vasopressors in the first week of life and their impact on outcomes of extremely preterm infants. Study Design Retrospective review of all newborns ≤28 weeks of gestational age (GA) admitted in neonatal intensive care unit from October 1, 2012 to October 31, 2015 done. Data regarding antenatal and neonatal characteristics and outcomes w...
Source: American Journal of Perinatology - May 14, 2021 Category: Perinatology & Neonatology Authors: Zaveri, Parul G. Walker, Amanda M. Upadhyay, Kirtikumar Talati, Ajay J. Tags: Original Article Source Type: research

Characteristics, management, and prognosis of elderly patients with COVID-19 admitted in the ICU during the first wave: insights from the COVID-ICU study
The COVID-19 pandemic is a heavy burden in terms of health care resources. Future decision-making policies require consistent data on the management and prognosis of the older patients (> 70 years old) with CO... (Source: Annals of Intensive Care)
Source: Annals of Intensive Care - May 14, 2021 Category: Intensive Care Authors: Martin Dres, David Hajage, Said Lebbah, Antoine Kimmoun, Tai Pham, Ga ëtan Béduneau, Alain Combes, Alain Mercat, Bertrand Guidet, Alexandre Demoule and Matthieu Schmidt Tags: Research Source Type: research

Severe acute respiratory syndrome coronavirus 2 infection and critically ill children
Purpose of review Amidst an ongoing pandemic, the delineation of the pediatric consequence of infection from the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV2) virus is emerging. This review summarizes available pediatric data and covers the aspects of epidemiology, critical illness with acute infection [coronavirus disease 2019 (COVID-19)], the discovered multi-inflammatory syndrome in children (MIS-C), and management options. Recent findings The available data from the source of the initial viral transmission and then through Europe, Africa, and the Western Hemisphere identifies important as...
Source: Current Opinion in Pediatrics - May 13, 2021 Category: Pediatrics Tags: EMERGENCY AND CRITICAL CARE MEDICINE: Edited by Jean E. Klig and Clifford W. Bogue Source Type: research

Maternal postpartum depression: risk factors, impacts, and interventions for the NICU and beyond
Purpose of review Postpartum depression (PPD) negatively impacts caregivers, infants, siblings, and entire families. Mothers with infants admitted to the neonatal intensive care unit (NICU) face additional risk for PPD, coupled with risk factors extending beyond a NICU admision. The novelty of this review is the focus on maternal PPD for mothers with infants admitted to the NICU. Interventions aimed at limiting and preventing PPD in this population include: prenatal and postpartum depression screening, PPD symptom awareness and monitoring, and trauma-informed care. Recent findings PPD, the most frequent complica...
Source: Current Opinion in Pediatrics - May 13, 2021 Category: Pediatrics Tags: OFFICE PEDIATRICS: Edited by Henry H. Bernstein Source Type: research

Family Members' Knowledge and Attitude Toward Life-Sustaining Treatment Decisions for Patients in the Intensive Care Unit
This study aimed to examine knowledge and attitude toward LST among the family members of patients under intensive care since the foundation of the new legislation. Their perceptions of the roles of nurses were also explored. In this cross-sectional study, 89 participants completed survey questionnaires on demographic characteristics, relationship to patient, reason for admission, length of stay, awareness of the new legislation, knowledge and attitude toward LST, and perception of the role of nurses. The results indicated that knowledge was significantly associated with attitude and was, in fact, the only predictor of att...
Source: Journal of Hospice and Palliative Nursing - May 13, 2021 Category: Nursing Tags: Feature Articles Source Type: research

Multimodal intervention to reduce acquisition of carbapenem-non-susceptible gram-negative bacteria in intensive care units in the National Referral Hospital of Indonesia: An interrupted time series study
Publication date: Available online 12 May 2021Source: Journal of Critical CareAuthor(s): Yulia Rosa Saharman, Anis Karuniawati, Rudyanto Sedono, Dita Aditianingsih, Hongchao Qi, Henri A. Verbrugh, Juliëtte A. Severin (Source: Journal of Critical Care)
Source: Journal of Critical Care - May 13, 2021 Category: Gastroenterology Source Type: research

Assessment of potential differences between pre-filled and manually prepared syringe use during vascular access device management in a pediatric intensive care unit
J Vasc Access. 2021 May 13:11297298211015500. doi: 10.1177/11297298211015500. Online ahead of print.ABSTRACTBACKGROUND: Central line-associated bloodstream infection is one of the four primary health-care-associated infections applicable to pediatric intensive care units defined by The Centers for Disease Control and Prevention. According to current guidelines, it is essential to flush vascular access devices before each infusion to assess catheter function and prevent catheter-related complications.OBJECTIVE: This prospective trial aimed to assess the potential differences between pre-filled and manually prepared saline s...
Source: The Journal of Vascular Access - May 13, 2021 Category: Surgery Authors: Gokhan Ceylan Sevgi Topal Nuriye Turgut Nihal Ozdamar Yeliz Oruc Hasan Agin Ilker Devrim Source Type: research

Minimum standards of clinical practice for physical therapists working in intensive care units in Japan
CONCLUSIONS: This is the first study to develop a consensus-based minimum clinical practice standard for physical therapists working in intensive care units in Japan.PMID:33981528 | PMC:PMC8111421 | DOI:10.1298/ptr.E10060 (Source: Physical Therapy)
Source: Physical Therapy - May 13, 2021 Category: Physiotherapy Authors: Tetsuya Takahashi Michitaka Kato Kengo Obata Ryo Kozu Toru Fujimoto Koji Yamashita Morihide Ando Yusuke Kawai Noriaki Kojima Hiroshi Komatsu Kensuke Nakamura Yuhei Yamashita Shane Patman Akemi Utsunomiya Osamu Nishida Source Type: research

Post-ICU Care in the Outpatient Setting
Am Fam Physician. 2021 May 15;103(10):590-596.ABSTRACTMore than 5 million patients in the United States are admitted to intensive care units (ICUs) annually, and an increasing percentage of patients treated in the ICU survive to hospital discharge. Because these patients require follow-up in the outpatient setting, family physicians should be prepared to provide ongoing care and screening for post-ICU complications. Risk factors for complications after ICU discharge include previous ICU admissions, preexisting mental illness, greater number of comorbidities, and prolonged mechanical ventilation or higher opioid exposure wh...
Source: American Family Physician - May 13, 2021 Category: Primary Care Authors: Jason Wilbur Jessica Rockafellow Brian Shian Source Type: research

Delirium and Associated Length of Stay and Costs in Critically Ill Patients
Crit Care Res Pract. 2021 Apr 24;2021:6612187. doi: 10.1155/2021/6612187. eCollection 2021.ABSTRACTPURPOSE: Delirium frequently affects critically ill patients in the intensive care unit (ICU). The purpose of this study is to evaluate the impact of delirium on ICU and hospital length of stay (LOS) and perform a cost analysis.MATERIALS AND METHODS: Prospective studies and randomized controlled trials of patients in the ICU with delirium published between January 1, 2015, and December 31, 2020, were evaluated. Outcome variables including ICU and hospital LOS were obtained, and ICU and hospital costs were derived from the res...
Source: Critical Care Research and Practice - May 13, 2021 Category: Intensive Care Authors: Claudia Dziegielewski Charlenn Skead Toros Canturk Colleen Webber Shannon M Fernando Laura H Thompson Madison Foster Vanja Ristovic Peter G Lawlor Dipayan Chaudhuri Chintan Dave Brent Herritt Shirley H Bush Salmaan Kanji Peter Tanuseputro Kednapa Thavorn Source Type: research

Subcostal TAPSE measured by anatomical M-mode: prospective reliability clinical study in critically ill patients
Minerva Anestesiol. 2021 May 13. doi: 10.23736/S0375-9393.21.15464-1. Online ahead of print.ABSTRACTBACKGROUND: Tricuspid annular plane systolic excursion (TAPSE), evaluated from a four-chamber apical view, is an echocardiographic parameter for the detection of right ventricular systolic dysfunction (RVD). We decided to assess the reliability of TAPSE measured from subcostal view (sTAPSE) by anatomical M-mode imaging (AMM) for evaluation of right ventricular systolic function and prediction of RVD in the critically ill patients by comparison with other echocardiographic parameters.METHODS: We conducted an observational, pr...
Source: Minerva Anestesiologica - May 13, 2021 Category: Anesthesiology Authors: Roman Škulec Tomas Parizek Barbora Stadlerova Marcela Bilska Vladimir Cerny Source Type: research

Diagnostic Value of High-Sensitivity Troponin T for Subclinical Left Ventricular Systolic Dysfunction in Patients with Sepsis
Cardiol Res Pract. 2021 Apr 23;2021:8897738. doi: 10.1155/2021/8897738. eCollection 2021.ABSTRACTBACKGROUND: Left ventricular systolic dysfunction (LVSD) is common in sepsis. Speckle-tracking echocardiography (STE) is a useful emerging tool for evaluating the intrinsic left ventricular systolic function. High-sensitivity cardiac troponin T (hs-cTnT) is the most sensitive biomarker of myocardial injury. However, there are limited data regarding the association between hs-cTnT level and left ventricular systolic dysfunction based on STE in septic patients. We performed this prospective study to evaluate the diagnostic value ...
Source: Cardiology Research and Practice - May 13, 2021 Category: Cardiology Authors: Pham Dang Hai Nguyen Thanh Binh Nguyen Hong Tot Ha Manh Hung Le Thi Viet Hoa Nguyen Viet Quang Hien Pham Nguyen Son Source Type: research

Plasma levels of bigEndothelin-1 are associated with renal insufficiency and in-hospital mortality of immune thrombotic thrombocytopenic purpura
Thromb Haemost. 2021 May 13. doi: 10.1055/a-1508-8347. Online ahead of print.ABSTRACTImmune thrombotic thrombocytopenic purpura (iTTP) is caused by severe deficiency of plasma ADAMTS13 activity. Despite advances in early diagnosis and management, the mortality rate of acute iTTP remains high in a large part of world where access to some of the most novel therapies is limited. To determine the role of plasma bigEndothelin-1 (bigET-1) or its bioactive product ET-1 as a biomarker and/or a pathogenic factor in acute iTTP, plasma levels of bigET-1 were determined using an immunoassay in patients with iTTP on admission and durin...
Source: Thrombosis and Haemostasis - May 13, 2021 Category: Hematology Authors: Ruinan Lu X Long Zheng Source Type: research

Delirium in adult patients in intensive care: nursing interventions
CONCLUSION: The interventions identified were predominantly aimed at the prevention of delirium. The training of nurses and wider clinical team in preventing and identifying this syndrome is crucial.PMID:33983821 | DOI:10.12968/bjon.2021.30.9.534 (Source: British Journal of Nursing)
Source: British Journal of Nursing - May 13, 2021 Category: Nursing Authors: Ana Filipa Gaud êncio Bento Patr ícia Pontífice Sousa Source Type: research

Assessment of potential differences between pre-filled and manually prepared syringe use during vascular access device management in a pediatric intensive care unit
J Vasc Access. 2021 May 13:11297298211015500. doi: 10.1177/11297298211015500. Online ahead of print.ABSTRACTBACKGROUND: Central line-associated bloodstream infection is one of the four primary health-care-associated infections applicable to pediatric intensive care units defined by The Centers for Disease Control and Prevention. According to current guidelines, it is essential to flush vascular access devices before each infusion to assess catheter function and prevent catheter-related complications.OBJECTIVE: This prospective trial aimed to assess the potential differences between pre-filled and manually prepared saline s...
Source: The Journal of Vascular Access - May 13, 2021 Category: Surgery Authors: Gokhan Ceylan Sevgi Topal Nuriye Turgut Nihal Ozdamar Yeliz Oruc Hasan Agin Ilker Devrim Source Type: research

Minimum standards of clinical practice for physical therapists working in intensive care units in Japan
CONCLUSIONS: This is the first study to develop a consensus-based minimum clinical practice standard for physical therapists working in intensive care units in Japan.PMID:33981528 | PMC:PMC8111421 | DOI:10.1298/ptr.E10060 (Source: Physical Therapy)
Source: Physical Therapy - May 13, 2021 Category: Physiotherapy Authors: Tetsuya Takahashi Michitaka Kato Kengo Obata Ryo Kozu Toru Fujimoto Koji Yamashita Morihide Ando Yusuke Kawai Noriaki Kojima Hiroshi Komatsu Kensuke Nakamura Yuhei Yamashita Shane Patman Akemi Utsunomiya Osamu Nishida Source Type: research

Post-ICU Care in the Outpatient Setting
Am Fam Physician. 2021 May 15;103(10):590-596.ABSTRACTMore than 5 million patients in the United States are admitted to intensive care units (ICUs) annually, and an increasing percentage of patients treated in the ICU survive to hospital discharge. Because these patients require follow-up in the outpatient setting, family physicians should be prepared to provide ongoing care and screening for post-ICU complications. Risk factors for complications after ICU discharge include previous ICU admissions, preexisting mental illness, greater number of comorbidities, and prolonged mechanical ventilation or higher opioid exposure wh...
Source: American Family Physician - May 13, 2021 Category: Primary Care Authors: Jason Wilbur Jessica Rockafellow Brian Shian Source Type: research

Delirium and Associated Length of Stay and Costs in Critically Ill Patients
Crit Care Res Pract. 2021 Apr 24;2021:6612187. doi: 10.1155/2021/6612187. eCollection 2021.ABSTRACTPURPOSE: Delirium frequently affects critically ill patients in the intensive care unit (ICU). The purpose of this study is to evaluate the impact of delirium on ICU and hospital length of stay (LOS) and perform a cost analysis.MATERIALS AND METHODS: Prospective studies and randomized controlled trials of patients in the ICU with delirium published between January 1, 2015, and December 31, 2020, were evaluated. Outcome variables including ICU and hospital LOS were obtained, and ICU and hospital costs were derived from the res...
Source: Critical Care Research and Practice - May 13, 2021 Category: Intensive Care Authors: Claudia Dziegielewski Charlenn Skead Toros Canturk Colleen Webber Shannon M Fernando Laura H Thompson Madison Foster Vanja Ristovic Peter G Lawlor Dipayan Chaudhuri Chintan Dave Brent Herritt Shirley H Bush Salmaan Kanji Peter Tanuseputro Kednapa Thavorn Source Type: research

Subcostal TAPSE measured by anatomical M-mode: prospective reliability clinical study in critically ill patients
Minerva Anestesiol. 2021 May 13. doi: 10.23736/S0375-9393.21.15464-1. Online ahead of print.ABSTRACTBACKGROUND: Tricuspid annular plane systolic excursion (TAPSE), evaluated from a four-chamber apical view, is an echocardiographic parameter for the detection of right ventricular systolic dysfunction (RVD). We decided to assess the reliability of TAPSE measured from subcostal view (sTAPSE) by anatomical M-mode imaging (AMM) for evaluation of right ventricular systolic function and prediction of RVD in the critically ill patients by comparison with other echocardiographic parameters.METHODS: We conducted an observational, pr...
Source: Minerva Anestesiologica - May 13, 2021 Category: Anesthesiology Authors: Roman Škulec Tomas Parizek Barbora Stadlerova Marcela Bilska Vladimir Cerny Source Type: research

Diagnostic Value of High-Sensitivity Troponin T for Subclinical Left Ventricular Systolic Dysfunction in Patients with Sepsis
Cardiol Res Pract. 2021 Apr 23;2021:8897738. doi: 10.1155/2021/8897738. eCollection 2021.ABSTRACTBACKGROUND: Left ventricular systolic dysfunction (LVSD) is common in sepsis. Speckle-tracking echocardiography (STE) is a useful emerging tool for evaluating the intrinsic left ventricular systolic function. High-sensitivity cardiac troponin T (hs-cTnT) is the most sensitive biomarker of myocardial injury. However, there are limited data regarding the association between hs-cTnT level and left ventricular systolic dysfunction based on STE in septic patients. We performed this prospective study to evaluate the diagnostic value ...
Source: Cardiology Research and Practice - May 13, 2021 Category: Cardiology Authors: Pham Dang Hai Nguyen Thanh Binh Nguyen Hong Tot Ha Manh Hung Le Thi Viet Hoa Nguyen Viet Quang Hien Pham Nguyen Son Source Type: research