Neurodevelopmental outcome at 5.5 years in Dutch preterm infants born at 24-26 weeks gestational age: the EPI-DAF study
Conclusions
After lowering the threshold for supporting active treatment from 25 to 24 completed weeks’ gestation, a considerable proportion of the surviving extremely preterm children did not have any impairment at 5.5 years’ CA. (Source: Archives of Disease in Childhood - Fetal and Neonatal Edition)
Source: Archives of Disease in Childhood - Fetal and Neonatal Edition - April 18, 2024 Category: Perinatology & Neonatology Authors: van Beek, P. E., Rijken, M., Broeders, L., ter Horst, H. J., Koopman-Esseboom, C., de Kort, E., Laarman, A. R. C., Mulder - de Tollenaer, S. M., Steiner, K., Swarte, R. M. C., van Westering-Kroon, E., Oei, G., Leemhuis, A. G., Andriessen, P. Tags: Open access Original research Source Type: research
Paediatric intensive care admissions of preterm children born
Conclusions
Most babies born <32 weeks and discharged home from neonatal care do not require PICU admission in the first 2 years. The odds of unplanned admissions to PICU were greater in the most preterm and those with significant neonatal morbidity. (Source: Archives of Disease in Childhood - Fetal and Neonatal Edition)
Source: Archives of Disease in Childhood - Fetal and Neonatal Edition - April 18, 2024 Category: Perinatology & Neonatology Authors: van Hasselt, T. J., Gale, C., Battersby, C., Davis, P. J., Draper, E., Seaton, S. E., On behalf of the United Kingdom Neonatal Collaborative and the Paediatric Critical Care Society Study Group (PCCS-SG) Tags: Open access Original research Source Type: research
Serial lactate measurements to guide resuscitation: more evidence not to?
(Source: Intensive Care Medicine)
Source: Intensive Care Medicine - April 18, 2024 Category: Intensive Care Source Type: research
Federated data access and federated learning: improved data sharing, AI model development, and learning in intensive care
(Source: Intensive Care Medicine)
Source: Intensive Care Medicine - April 18, 2024 Category: Intensive Care Source Type: research
Genes, Vol. 15, Pages 505: Clinical Decision Analysis of Genetic Evaluation and Testing in 1013 Intensive Care Unit Infants with Congenital Heart Defects Supports Universal Genetic Testing
are
Extracardiac anomalies (ECAs) are strong predictors of genetic disorders in infants with congenital heart disease (CHD), but there are no prior studies assessing performance of ECA status as a screen for genetic diagnoses in CHD patients. This retrospective cohort study assessed this in our comprehensive inpatient CHD genetics service focusing on neonates and infants admitted to the intensive care unit (ICU). The performance and diagnostic utility of using ECA status to screen for genetic disorders was assessed using decision curve analysis, a statistical tool to assess clinical utility, determining the threshold o...
Source: Genes - April 18, 2024 Category: Genetics & Stem Cells Authors: Benjamin M. Helm Stephanie M. Ware Tags: Article Source Type: research
Informed non-dissent for brain death testing in children: ethical and legal perspectives
A 14-year-old girl, Hana, is admitted to the paediatric intensive care unit following a sudden collapse at home. She is found to have sustained a severe haemorrhagic stroke. Despite emergency neurosurgical intervention, she deteriorates over several days. Her family have been struggling to accept the possibility that she would not recover. Hana remains unresponsive, has fixed dilated pupils and has developed diabetes insipidus. The clinical team suspect that she is brain dead. Should the family’s consent be sought for brain death testing? (This case is fictitious.) In mid-2022, the high profile case of Archie Batters...
Source: Archives of Disease in Childhood - April 18, 2024 Category: Pediatrics Authors: Wilkinson, D., Miller, C., Turner, S. W. Tags: Ethics and law for clinical practice Source Type: research
Characteristics of children requiring admission to neonatal care and paediatric intensive care before the age of 2 years in England and Wales: a data linkage study
Conclusions
Healthcare professionals caring for babies and children in NNU and PICU see some of the same children in the first 2 years of life. While some children are following established care pathways (eg, staged cardiac surgery), the small proportion of children needing NNU care subsequently requiring PICU care account for a large proportion of the total PICU population. These differences may affect perceptions of risk for this group of children between NNU and PICU teams. (Source: Archives of Disease in Childhood)
Source: Archives of Disease in Childhood - April 18, 2024 Category: Pediatrics Authors: Seaton, S. E., Battersby, C., Davis, P. J., Fenton, A. C., Anderson, J., van Hasselt, T. J., Draper, E. Tags: Open access Original research Source Type: research
Skeletal surveys in intubated patients: does UK clinical practice match national guidelines?
Introduction The investigation of suspected paediatric non-accidental injury in children under 2 years of age includes a skeletal survey, which is also indicated in older children on a case-by-case basis. In 2018, the UK national standards for the ‘radiological investigation of suspected physical abuse in children’ were updated by relevant radiology and radiography bodies and endorsed by the Royal College of Paediatrics and Child Health.1 The standards now mandate a skeletal survey within 72 hours of presentation, ideally within 24 hours. Initial and targeted follow-up images facilitate the crucial timing of an...
Source: Archives of Disease in Childhood - April 18, 2024 Category: Pediatrics Authors: Manning, G. L. P., Sharpe, E., Calder, A., Brierley, J. Tags: PostScript Source Type: research
Accuracy of point-of-care testing for the diagnosis of respiratory pathogens in a paediatric intensive care setting
Respiratory tract infections contribute significantly to paediatric intensive care unit (PICU) admissions. Early diagnosis supports treatment, cohorting and antimicrobial stewardship. Rapid point-of-care (POC) multiplex PCR techniques show promise in improving antimicrobial and investigation stewardship across healthcare settings.1 However, debate exists regarding their role and accuracy.2 3 We sought to evaluate the feasibility and accuracy of respiratory pathogen POC testing in our PICU. All patients admitted to the regional Northern Ireland PICU undergo nasal/nasopharyngeal swab respiratory pathogen POC testing. The Bio...
Source: Archives of Disease in Childhood - April 18, 2024 Category: Pediatrics Authors: Norman - Bruce, H., Wilson, K., Waheed, S., Richardson, J., Groves, H. Tags: PostScript Source Type: research
Monocyte HLA ‐DR level on admission predicting in‐hospital mortality rate in exertional heatstroke: A 12‐year retrospective study
ConclusionPatients with EHS were at a risk of early experiencing decreased mHLA-DR early. A nomogram based on mHLA-DR with GCS was developed to facilitate early identification and timely treatment of individuals with potentially poor prognosis. (Source: Immunity, Inflammation and Disease)
Source: Immunity, Inflammation and Disease - April 17, 2024 Category: Allergy & Immunology Authors: Fanfan Wang,
Fanghe Gong,
Xuezhi Shi,
Jiale Yang,
Jing Qian,
Lulu Wan,
Huasheng Tong Tags: ORIGINAL ARTICLE Source Type: research
Predicting the risk of early intensive care unit admission for patients hospitalized with acute pancreatitis using supervised machine learning
CONCLUSIONS: This supervised machine learning-based model can help recognize high-risk AP hospitalizations. Clinicians may use the IAPR score to identify patients with AP at high risk of ICU admission within the first week of hospitalization.PMID:38628340 | PMC:PMC11018057 | DOI:10.1080/08998280.2024.2326371 (Source: Baylor University Medical Center Proceedings)
Source: Baylor University Medical Center Proceedings - April 17, 2024 Category: Universities & Medical Training Authors: Hassam Ali Faisal Inayat Rubaid Dhillon Pratik Patel Arslan Afzal Christin Wilkinson Attiq Ur Rehman Muhammad Sajeel Anwar Gul Nawaz Ahtshamullah Chaudhry Junaid Rasul Awan Muhammad Sohaib Afzal Jayanta Samanta Douglas G Adler Babu P Mohan Source Type: research
Risk factors and mortality of candidemia in a children's public hospital in Sao Paulo, Brazil
This study aimed to estimate the incidence and risk factors associated with mortality in candidemia cases occurring in a public children's hospital in Ribeirao Preto, Brazil. It is a retrospective transversal study. Every patient under the age of 18 admitted to the study facility from January 1, 2013, to December 31, 2019, was considered potentially eligible to be included if they had candidemia. We collected clinical data from medical records. We included 113 blood cultures yielding positive results for Candida. The incidence rate was 2.12 per 1000 admissions. The most common Candida species was Candida parapsilosis. Sept...
Source: Revista Argentina de Microbiologia - April 17, 2024 Category: Microbiology Authors: Rodrigo Groisman Sieben Rolando Paternina-de la Ossa Amaury Waack Davi Casale Aragon Fernando Bellissimo-Rodrigues Seila Israel do Prado Maria Celia Cervi Source Type: research
Coping strategies of intensive care unit nurses reducing moral distress: A content analysis study
DISCUSSION: The intensive care unit nurses in dealing with ethical problems first try to solve the problem through discussion, but when they fail to resolve it peacefully, they resort to several coping strategies. Factors, such as increasing experience, lack of support from hospital managers and officials, poor communication between colleagues, the need to maintain hierarchy, fear of reprimand, and a sense of powerlessness, changed the nurses' preferred strategies. It is important for managers to provide a blame/punishment-free atmosphere for expression of ethical experiences; a supportive atmosphere in which staff can eng...
Source: Nursing Ethics - April 17, 2024 Category: Nursing Authors: Maryam Esmaeili Mojdeh Navidhamidi Saeideh Varasteh Source Type: research
Transmastoid pediatric penetrating brain injury, interdisciplinary, and tailored patient's treatment
CONCLUSION: Radiological tools, notably skull X-rays and head CT scans, are pivotal for the precise diagnosis of pediatric PBI. The combined mastoidectomy and retro sigmoid craniotomy approach offers a safe and efficient means of foreign body removal. Tailoring treatments to individual patient needs enhances outcomes.PMID:38628538 | PMC:PMC11021077 | DOI:10.25259/SNI_18_2024 (Source: Surgical Neurology International)
Source: Surgical Neurology International - April 17, 2024 Category: Neurosurgery Authors: Tommy Alfandy Nazwar Farhad Bal'afif Donny Wisnu Wardhana Akmal Niam Firdaus Masyhudi Christin Panjaitan Source Type: research
Periprocedural management of ruptured blister aneurysms treated with pipeline flow diversion
CONCLUSION: Despite the need for dual antiplatelet therapy and the delayed occlusion of blister aneurysms treated with flow diversion, we did not find an increase in periprocedural complications.PMID:38628521 | PMC:PMC11021073 | DOI:10.25259/SNI_482_2023 (Source: Surgical Neurology International)
Source: Surgical Neurology International - April 17, 2024 Category: Neurosurgery Authors: Jessa E Hoffman Brent Morel Blake Wittenberg David Kumpe Joshua Seinfeld Zach Folzenlogen David Case Robert Neumann Luis Cava Robert Breeze Laura Wiley Christopher Roark Source Type: research
