The Perfect Gift!
This holiday season, we are all in search of the perfect gift. What is the one thing you truly desire for yourself and your family? Don’t you think we all want it? What if you were handed a beautifully wrapped box containing a miraculous tool that caused dramatic weight loss and good health without limiting calories or requiring exercise? What if this gift reduced appetite, shrunk belly fat, and dropped your dress size? What if that same gift freed you from acid reflux, heartburn, bowel urgency, and diarrhea, but also improved mood, increased energy, deepened sleep, and reduced or eliminated joint pain? And all of this m...
Source: Wheat Belly Blog - November 26, 2021 Category: Cardiology Authors: April Duval Tags: Open Source Type: blogs

Food Intolerances: A Warning of Bad Things Ahead
I’ve recently discussed how the majority of food intolerances, whether to FODMAPs, histamine, nightshades, fructose, etc., are really manifestations of dysbiosis and SIBO. Here is another way to view these phenomena: Food intolerances are your body’s signal to you that serious deterioration in your health is coming. In other words, if all you do is choose to reduce or eliminate the offending food, you are still left with the massive disruption of your intestinal microbiome that caused the food intolerance in the first place, along with increased intestinal permeability and endotoxemia. So say you eliminate ferm...
Source: Wheat Belly Blog - November 1, 2021 Category: Cardiology Authors: Dr. Davis Tags: Open microbiota prebiotic probiotic sibo small intestinal bacterial super gut undoctored wheat belly Source Type: blogs

Gastroenterology Embraces Artificial Intelligence
AI and machine learning have the potential to redefine the management of several GI disorders.John Halamka, M.D., president, Mayo Clinic Platform, and Paul Cerrato, senior research analyst and communications specialist, Mayo Clinic Platform, wrote this article.Colonoscopy is one of the true success stories in modern medicine.Studies have demonstrated that colonoscopy screening detects the cancer at a much earlier stage, reducing the risk of invasive tumors and metastatic disease, andreducing mortality. However, while colorectal cancer is highly preventable, it is thethird leading cause of cancer-related deathsin the U.S. A...
Source: Life as a Healthcare CIO - October 13, 2021 Category: Information Technology Source Type: blogs

Big Pharma, Big Money: Johnson & Johnson, Pfizer, Bayer, Novartis in digital health
In a recent series of articles, we explored the latest moves of Tech Giants like Amazon, NVIDIA and Microsoft in the field of digital health. Analysing these recent developments can give us a better idea regarding where they are focusing the efforts, and how it might shape the future path of healthcare.  But equally, if not more, strong players in this field are pharmaceutical giants, as their resources and influence can significantly shape or alter the course of this path. As such, we are kickstarting a new series of articles focusing on the digital health efforts of 14 global pharma companies. While those heavywe...
Source: The Medical Futurist - October 12, 2021 Category: Information Technology Authors: Pranavsingh Dhunnoo Tags: Future of Medicine Future of Pharma digital health novartis pfizer J&J big pharma Johnson&Johnson Bayer Source Type: blogs

Thought experiment: Would therapists be out of a job if we could “ fix ” persistent pain?
Every few years someone, somewhere, announces that “it won’t be long before we have a treatment to rid the world of persistent pain.” And there’s a hiss and roar to celebrate this momentous finding, and much ado about how wonderful it will be. I’m still waiting. BUT I thought it might be an interesting thought experiment to wonder what might happen if a “cure” was available for fibromyalgia. As readers will know, I have lived with what eventually was named “fibromyalgia” since my early 20’s, and probably longer. I’ve dabbled in various treatments ove...
Source: HealthSkills Weblog - October 10, 2021 Category: Anesthesiology Authors: BronnieLennoxThompson Tags: Chronic pain Pain conditions Professional topics Research Science in practice biopsychosocial pain management Therapeutic approaches Source Type: blogs

Fight Aging! Newsletter, September 6th 2021
In conclusion, patients over 90 years of age had an overall low prevalence of fractures and relative preservation of bone health, suggesting a preserved bone molecular profile in these individuals. Epigenetic factors and activity levels might also have favorably affected bone health. The low percentage of osteoporosis and fractures likely reduced the morbidity and mortality in this population, potentially contributing to their overall longevity. Building a Therapy for Aging Based on SIRT6 Upregulation https://www.fightaging.org/archives/2021/08/building-a-therapy-for-aging-based-on-sirt6-upregulation/ G...
Source: Fight Aging! - September 5, 2021 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Fecal Microbiota Transplant as a Treatment for Neurodegenerative Conditions
It is thought that an appreciable fraction of the chronic inflammation of aging is caused by changes in the gut microbiome. There is a bidirectional interaction between the immune system and the microbial populations of the intestinal tract. The immune system gardens these populations, destroying problematic microbes. Microbes secrete metabolites and other molecules that can either benefit or harm the function of the immune system, the harms caused particularly by those microbes capable of provoking a sustained inflammatory response. The immune system declines with age for a range of reasons, and reduced efficacy in immune...
Source: Fight Aging! - September 3, 2021 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs

Future Treatment For Autoimmune Diseases
New digital health tech targeted to fight autoimmune diseases or their symptoms are diverse and creative. These often completely different illnesses, like type 1 diabetes, inflammatory bowel disease, rheumatoid arthritis, and multiple sclerosis, indicate an immune system dysfunction. Immune cells and mechanisms target the body’s own cells and structures, deconstructing it bit by bit and inducing inflammation. An estimated 24-50 million people in the US alone are living with autoimmune conditions. It affects their day-to-day life, but scientists suggest people living with chronic conditions could also be more suscepti...
Source: The Medical Futurist - July 29, 2021 Category: Information Technology Authors: szandra Tags: Biotechnology Future of Medicine Portable Medical Diagnostics Telemedicine & Smartphones chatbot diabetes digital health sleep optimization chronic pain chronic illness skin coronavirus autoimmune disease Source Type: blogs

Kirigami Stent for Localized Drug Delivery
Researchers at MIT have developed a kirigami-style stent that can provide localized drug delivery through needle-like projections that pop out when the stent is extended. The ‘spines’ on the stent’s surface deliver drug-loaded microparticles into the surrounding tissue, allowing for sustained drug release for an extended period. The technology is well suited to administering drugs within tubular structures, such as those found in the GI tract, the respiratory system, and blood vasculature. Treating inflammatory gastrointestinal conditions, such as inflammatory bowel disease, is frequently performed through the...
Source: Medgadget - June 15, 2021 Category: Medical Devices Authors: Conn Hastings Tags: GI Materials Medicine Vascular Surgery Source Type: blogs

Is IBD an underrecognized health problem in minority groups?
As many people know, inflammatory bowel disease (IBD) is a complex condition affecting the intestine, which is the part of the digestive tract that helps digest food and remove water, salt, and waste. But you might not know this: in recent years in the US, IBD is being diagnosed more often among people who are Black, Hispanic/Latinx, East and Southeast Asian, or from other minority groups than it was in past decades. Is this a true rise in cases? Is IBD underrecognized in minority populations? While we don’t have all the answers yet, exploring health disparities in IBD and explaining its symptoms may encourage more peopl...
Source: Harvard Health Blog - May 7, 2021 Category: Consumer Health News Authors: Adjoa Anyane-Yeboa, MD, MPH Tags: Digestive Disorders Health Health care disparities Inflammation Source Type: blogs

Fight Aging! Newsletter, April 19th 2021
In conclusion, airway pressure treatment and adherence are independently associated with lower odds of incident AD diagnoses in older adults. Results suggest that treatment of OSA may reduce risk of subsequent dementia. (Source: Fight Aging!)
Source: Fight Aging! - April 18, 2021 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Sweat Sensor Warns of Impending COVID-19 Cytokine Storm
Researchers at the University of Texas and EnLiSense, a Texas startup, have developed a skin sweat sensor that can measure cytokine levels continuously for up to 168 hours. The technology has been adapted so that it can detect cytokines involved in the deadly cytokine storms that occur in patients with COVID-19 and other illnesses, such as influenza. The researchers hope that it might serve as an early warning system for an impending storm, allowing early treatment. Cytokine storms involve a massive release of pro-inflammatory cytokines, leading to intense inflammation that can cause significant damage to organs, someti...
Source: Medgadget - April 16, 2021 Category: Medical Devices Authors: Conn Hastings Tags: Cardiology Critical Care Medicine Public Health Source Type: blogs

In Horses, the Gut Microbiome Interacts with Mitochondria to Improve Function
The study here is carried out in horses, but it is reasonable to expect to find very similar mechanisms in other mammals. The beneficial populations of the gut microbiome provide metabolites that steer cell function and exist in symbiosis with the host animal. Mitochondria, the power plants of the cell, are the evolved descendants of ancient symbiotic microbes, now an integral part of cellular processes. It is reasonable to think that the one can influence the other directly via signaling processes, as researchers discuss in these materials and elsewhere. In humans, for example, researchers have found that propionate gener...
Source: Fight Aging! - April 14, 2021 Category: Research Authors: Reason Tags: Daily News Source Type: blogs

Beyond CBD: Here come the other cannabinoids, but where ’s the evidence?
In the span of a few years, the component of cannabis called CBD (cannabidiol) went from being a relatively obscure molecule to a healthcare fad that has swept the world, spawning billions in sales, millions of users, CBD workout clothing, pillowcases, hamburgers, ice cream — you name it. The concerns of such a rapid adoption are that enthusiasm might be soaring high above the actual science, and that there are safety issues, such as drug interactions, that are given short shrift in the enthusiasm to treat chronic pain, insomnia, anxiety, and many of the other conditions that CBD is believed to help alleviate. Cannabis, ...
Source: Harvard Health Blog - March 23, 2021 Category: Consumer Health News Authors: Peter Grinspoon, MD Tags: Complementary and alternative medicine Drugs and Supplements Fatigue Marijuana Pain Management Source Type: blogs

Fight Aging! Newsletter, March 1st 2021
This study may have important implications for preventing cell senescence and aging-induced tendinopathy, as well as for the selection of novel therapeutic targets of chronic tendon diseases. Our results showed that the treatment of bleomycin, a DNA damaging agent, induced rat patellar TSC (PTSC) cellular senescence. The senescence was characterized by an increase in the senescence-associated β-galactosidase activity, as well as senescence-associated changes in cell morphology. On the other hand, rapamycin could extend lifespan in multiple species, including yeast, fruit flies, and mice, by decelerating DNA damage ...
Source: Fight Aging! - February 28, 2021 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs