Genetic Variants are not an Important Risk Factor in the Vast Majority of People and Age-Related Conditions
This is an age of genetics, in which the costs of obtaining and working with genetic data have dropped by orders of magnitude, while the capabilities of the tools and technologies have expanded to a similar degree. Give the scientific community a hammer, and a great many parts of the field start to look like a nail. Thus there are innumerable studies of genetics and longevity, genetics and specific age-related diseases, and so forth. There is considerable interest in trying to find out whether there is a genetic contribution to survival to extreme old age, and then using this information to develop therapies.
What t...
Source: Fight Aging! - December 27, 2019 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs
Podcast: Stopping Psych Meds; What To Consider
Medication for your brain – whether you’re newly diagnosed or have been in treatment for years, you may have doubts if drugs are right for you. You’re not alone. Jackie and Gabe get real about reasons people want to quit psych meds and why our brains convince us to quit despite the benefits of taking medication. They discuss consequences you may not be aware of from just stopping your meds and why you should always involve your doctors, no matter what your decision, when it comes to medication.
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About The Not Crazy Podcast Hosts
Gabe Howard is an award-w...
Source: World of Psychology - December 23, 2019 Category: Psychiatry & Psychology Authors: Not Crazy Podcast Tags: Antidepressant Antipsychotic Medications Not Crazy Podcast Psychology Stimulants Treatment Source Type: blogs
Fight Aging! Newsletter, December 23rd 2019
In this study, by adenovirus-mediated delivery and inducible transgenic mouse models, we demonstrate the proliferation of both HCs and SCs by combined Notch1 and Myc activation in in vitro and in vivo inner ear adult mouse models. These proliferating mature SCs and HCs maintain their respective identities. Moreover, when presented with HC induction signals, reprogrammed adult SCs transdifferentiate into HC-like cells both in vitro and in vivo. Finally, our data suggest that regenerated HC-like cells likely possess functional transduction channels and are able to form connections with adult auditory neurons.
Epige...
Source: Fight Aging! - December 22, 2019 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Immunization Against Flagellin as a Way to Beneficially Alter Aging Gut Microbiota Populations
The microbial populations of the gut make a significant contribution to health via secreted metabolites and interactions with the immune system. Starting in mid-life, these populations alter for the worse, and this is thought to influence the progression of aging - perhaps primarily as a contributing cause of chronic inflammation. How this effect size compares with those resulting from dietary and exercise choices is an open question, but it isn't unreasonable to suggest it to be in the same ballpark as exercise.
What can be done to improve this situation? Supplementation with metabolites produced in larger amounts ...
Source: Fight Aging! - December 18, 2019 Category: Research Authors: Reason Tags: Daily News Source Type: blogs
Podcast: Newly Bipolar & Learning to Adapt
You’ve just been diagnosed with bipolar disorder… now what? The week we interview a young woman named Emma, a twenty-something who is fresh off a bipolar diagnosis and working hard to navigate her way through finding the right medications, a treatment plan that works, and navigating tough family conversations.
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About The Not Crazy Podcast Hosts
Gabe Howard is an award-winning writer and speaker who lives with bipolar disorder. He is the author of the popular book, Mental Illness is an Asshole and other Observations, available from Amazon; signed copies ar...
Source: World of Psychology - December 16, 2019 Category: Psychiatry & Psychology Authors: Not Crazy Podcast Tags: Bipolar Medications Not Crazy Podcast Psychotherapy Source Type: blogs
Bacterial Hydrogel Adheres to Gut to Treat Inflammatory Bowel Disease
Researchers at Harvard’s Wyss Institute have developed a living bacterial hydrogel that can adhere to lesions in the gut wall to encourage healing and reduce inflammation. Consisting of genetically engineered bacteria that produce nanofibers that adhere to mucus, the resulting hydrogel could function as a novel probiotic therapy for inflammatory bowel disease.
Approximately 1.6 million people in the US have incurable inflammatory bowel disease, in which immune dysregulation and microbial factors in the gut contribute to lesions and inflammation in the gut lining. At present, anti-inflammatory drugs and antibiotic...
Source: Medgadget - December 9, 2019 Category: Medical Devices Authors: Conn Hastings Tags: GI Materials Source Type: blogs
Podcast | Survive the Holidays AND preserve your Mental Health
There is no time more joyous and stressful as the end of year holidays. As we fast approach the holidays this year it’s time to start thinking about how you’ll navigate family parties and other familial obligations. In this episode, we give our best tips for making holiday parties less stressful and how to decide if not going is the best option for you.
It’s rough out there, but we care about you and we wish you a happy, healthy holiday season.
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About The Not Crazy Podcast Hosts
Gabe Howard is an award-winning writer and speaker who lives with bipolar disorder...
Source: World of Psychology - December 9, 2019 Category: Psychiatry & Psychology Authors: Not Crazy Podcast Tags: Anxiety and Panic Depression Family General Holiday Coping Not Crazy Podcast Source Type: blogs
Podcast | Chronic Illness and Depression
After receiving two chronic illness diagnosis by the age of 24, it really was no surprise that host Jackie Zimmerman also started to experience depression. Unable to tackle both, Jackie chose to focus on her physical health, letting her mental health deteriorate quickly — and dangerously. In this episode, we discuss the mind-body connection and how when your body is sick, your mind can quickly follow.
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About The Not Crazy Podcast Hosts
Gabe Howard is an award-winning writer and speaker who lives with bipolar disorder. He is the author of the popular book...
Source: World of Psychology - December 2, 2019 Category: Psychiatry & Psychology Authors: Not Crazy Podcast Tags: Antidepressant Depression Medications Not Crazy Podcast Stress Suicide Trauma Source Type: blogs
Living with Crohn ’s disease: Recognizing and managing flares
Crohn’s disease is an inflammatory condition that can affect any part of the gastrointestinal tract. Together with ulcerative colitis, Crohn’s is one of the two main types of inflammatory bowel disease (IBD). Crohn’s affects approximately 500,000 Americans and is a chronic, lifelong condition that typically alternates between periods of relatively stable or absent symptoms (remission) and periods of symptom flare-ups that can last for days, weeks, or even months.
The goal of treatment is to induce remission and then to maximize the chance that patients stay in remission. However, almost everyone with Crohn’s diseas...
Source: Harvard Health Blog - November 26, 2019 Category: Consumer Health News Authors: John Garber, MD Tags: Digestive Disorders Health Source Type: blogs
Podcast | Psychiatric Ward: First Hand Account (Part 2 of 2)
In part two of this series, we go into more detail about Gabe’s inpatient hospital stay and focus on what he was thinking while he was hospitalized and what he learned after he was discharged. We talked about what to do if you feel like you need to be hospitalized, the steps you need to take in order to be admitted and the obstacles involved with getting the help you may need.
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About The Not Crazy Podcast Hosts
Gabe Howard is an award-winning writer and speaker who lives with bipolar disorder. He is the author of the popular book, Mental Illness is an Asshole...
Source: World of Psychology - November 25, 2019 Category: Psychiatry & Psychology Authors: Not Crazy Podcast Tags: Bipolar Depression Not Crazy Podcast Trauma Treatment Source Type: blogs
Podcast | Inpatient Mental Hospital Stay (Part 1 of 2)
Have you ever wondered what it’s like to be an inpatient in a psych ward? In this two-part series, we go into detail about Gabe’s inpatient stay starting with the events that lead him to be an inpatient, and what his days were like after he was admitted. We talk about common misconceptions that you may have around what happens while you’re admitted, what your day looks like and who you’d spend time with.
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About The Not Crazy Podcast Hosts
Gabe Howard is an award-winning writer and speaker who lives with bipolar disorder. He is the author of the popular boo...
Source: World of Psychology - November 18, 2019 Category: Psychiatry & Psychology Authors: Not Crazy Podcast Tags: Bipolar Depression General Not Crazy Podcast Psychiatry Psychotherapy Suicide Treatment Source Type: blogs
Podcast | Abandoned: Loss of Friendships
The feeling of abandonment can span through all types of relationships and in this episode, we focus on friendships. Have you ever had a close friend abandon you or have you ever exited a friendship without notice? The emotions and actions surrounding the abandonment of friends can be complex and hurtful, but they are very real and can hurt deeply.
In this episode, Jackie recounts friendships that were very important to her and how she’s handling the loss of them.
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About The Not Crazy Podcast Hosts
Gabe Howard is an award-winning writer and speaker who lives with...
Source: World of Psychology - November 11, 2019 Category: Psychiatry & Psychology Authors: Not Crazy Podcast Tags: Communication Family Friends General Grief and Loss Not Crazy Podcast Relationships Source Type: blogs
Podcast | Therapy Myths & Misconceptions
While therapy is often used as one method of treatment for mental illness, it still has a large cloud of mystery around it. Due to its portrayal in movies and television shows, there are a lot of misconceptions about what it means to go to therapy, what a session looks like and what the benefits to therapy can be.
In this episode, we talk about some of the common myths surrounding therapy, touch on the different types of therapy and why Jackie loves therapy so much.
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About The Not Crazy Podcast Hosts
Gabe Howard is an award-winning writer and speaker who lives with...
Source: World of Psychology - November 4, 2019 Category: Psychiatry & Psychology Authors: Not Crazy Podcast Tags: Happiness Mental Health and Wellness Not Crazy Podcast Psychiatry Psychology Psychotherapy Stigma Treatment Source Type: blogs
Podcast: Haunted Asylums – Stigmatizing or Just Entertainment?
Each Halloween we encounter the same debate: are haunted asylums stigmatizing or are they simply entertainment? While some may think haunted asylums are tasteless at worst, they don’t feel like they’re an actual detriment to the mental illness community. In this episode, we look at this argument from both sides and really dig into what happens when we use mental illness as a theme for entertainment. While Jackie and Gabe both make great arguments, we toss this question back to you.
Are you offended by haunted asylums or do you see them as harmless entertainment — or something in between? Listen now and decide...
Source: World of Psychology - October 28, 2019 Category: Psychiatry & Psychology Authors: Not Crazy Podcast Tags: General Not Crazy Podcast Stigma Trauma Source Type: blogs
Podcast: Psychiatric Medications: Separating Fact From Fiction
Psychiatric medications are the religion and politics of the mental health advocacy world — don’t bring them up unless you want a fight to break out. Luckily, here at Not Crazy, we don’t shy away from confrontation.
In this episode, we cover the good, the bad, and the ugly surrounding medications. Like whether or not you should take them. We tackle side effects like feeling numb and sexual dysfunction and share our personal histories with medication therapy. Listen now!
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About The Not Crazy Podcast Hosts
Gabe Howard is an award-winning write...
Source: World of Psychology - October 21, 2019 Category: Psychiatry & Psychology Authors: Not Crazy Podcast Tags: Antidepressant Antipsychotic General Medications Mental Health and Wellness Not Crazy Podcast Psychology Research Sexuality Stimulants Treatment Source Type: blogs
