How Your Brain Is Connected to Your Gut: 7 Facts About Gut Health
We've all had a "gut feeling," or someone has told us to "follow our gut." It's that feeling that we may know something just by knowing—our intuition telling us something. It turns out that this feeling is more than just a feeling. The human body is an intricate series of systems, each individually playing a vital role in our overall health and well-being, and at the same time, they are all connected to make our whole body work.  One of these systems is the gut, also known as the gastrointestinal tract, which is responsible for digesting food and absorbing nutrients. When we combine its superpowers with the brain...
Source: PickTheBrain | Motivation and Self Improvement - April 28, 2023 Category: Consumer Health News Authors: Irene Rondom Tags: health and fitness self-improvement brain health gut health Source Type: blogs

Neuroimmune Modulation for Inflammatory Disease: Interview with Dr. Simhambhatla, President and CEO of SetPoint Medical
SetPoint Medical, a medtech company based in California, is developing a neuromodulatory device that is intended to treat rheumatoid arthritis. The overlap between the nervous and immune systems is increasingly appreciated, and this technology aims to capitalize on this to create a new treatment for inflammatory disease. The neuromodulation device is intended to be implanted on the left cervical vagus nerve in an outpatient procedure. It stimulates the nerve with electrical pulses. The idea is that this can act to calm inflammatory processes that contribute to rheumatoid arthritis, without the drawbacks of immunosuppres...
Source: Medgadget - February 28, 2023 Category: Medical Devices Authors: Conn Hastings Tags: Exclusive Medicine Neurology autoimmune immunology SetPointMed Source Type: blogs

Farewell, Landleigh Nelson. I (and others) in the Diabetes Community Will Miss You.
Over the weekend, I learned that Landileigh Lee (James) Nelson died on Tuesday, January 10, 2023. As many of her friends knew, in recent years, Landileigh (or as those closest to her called her " Landi " ) had been dealing with a number of health issues. She faced seemingly one health issue after another, including dialysis which began at one point. And yet she handled it all incredibly gracefully and with her typical sense of humor, which was one reason I was proud to call Landileigh my friend.In 2017, Landi posted that she had gotten a new haircut on Facebook. I thought it was a nice photo of her, and this is how I wish ...
Source: Scott's Web Log - January 18, 2023 Category: Endocrinology Tags: 2023 Landi Landileigh Nelson Obituary passage tribute Source Type: blogs

Farewell, Landleigh Nelson. I (and others in the Diabetes Community) Will Miss You.
Over the weekend, I learned that Landileigh Lee (nee James) Nelson died on Tuesday, January 10, 2023. As many of her friends knew, in recent years, Landileigh (or as those closest to her called her " Landi " ) had been dealing with a number of health issues. She faced seemingly one health issue after another, including dialysis which began at one point. And yet she handled it all incredibly gracefully and with her typical sense of humor, which was one reason I was proud to call Landileigh my friend.In 2017, Landi posted that she had gotten a new haircut on Facebook. I thought it was a nice photo of her, and this is how I w...
Source: Scott's Web Log - January 18, 2023 Category: Endocrinology Tags: 2023 Landi Landileigh Nelson Obituary passage tribute Source Type: blogs

Netflix for Drugs?
By KIM BELLARD A relative — obviously overestimating my healthcare expertise — asked my thoughts on The New York Times article Can a Federally Funded ‘Netflix Model’ Fix the Broken Market for Antibiotics? I had previously skimmed the article and was vaguely aware of the Pasteur Act that it discusses, but, honestly, my immediate reaction to the article was, gosh, that may not be a great analogy: do people realize what a tough year Netflix has had? I have to admit that I tend to stay away from writing about Big Pharma and prescription drugs, mainly because, in a US healthcare system that seems to pride i...
Source: The Health Care Blog - December 21, 2022 Category: Consumer Health News Authors: matthew holt Tags: The Business of Health Care Congress Kim Bellard Netflix Pharma Pharmaceutical industry Source Type: blogs

I am stupid
Conclusion: Isaac Asimov is stupid(Sorry, no post yesterday because I was doing some heavy cerebral processing.)He ' d have been the first to admit it. All of us are susceptible to cognitive errors and biases. I ' d like to think that Asimov was less susceptible than most, but he must have had his own foibles. It ' s a constant struggle to be mindful and think straight. For my own part, I once had a romanticized view of the Chinese revolution, I was an anthropogenic climate change skeptic, and I entertained the likelihood that medical intervention, on balance, did more harm than good. (Viz Illich, Medical Nemesis.)&nb...
Source: Stayin' Alive - October 28, 2022 Category: American Health Source Type: blogs

I Suspect It Says Something That A Three Million Dollar Grant In Digital Health Makes News!
This release appeared last week.ANDHealth - Special Announcement: 7 September 2022ANDHealth, Australia ’s leading digital health commercialisation organisation, in partnership with the Victorian Government, today announced it has received $2.4M from the Australian Medtech Manufacturing Centre and Biotechnology Fund to create the Victorian Connected Health Innovation& Commercialisation Centre (CHICC).The CHICC has been established to drive the creation and commercialisation of digital and digitally enabled medical technology companies and raise Victoria ’s profile as a leading centre for Australia’s fast grow...
Source: Australian Health Information Technology - September 14, 2022 Category: Information Technology Authors: Dr David G More MB PhD Source Type: blogs

Weekly Australian Health IT Links – 12 September, 2022.
Here are a few I have come across the last week or so. Note: Each link is followed by a title and a few paragraphs. For the full article click on the link above title of the article. Note also that full access to some links may require site registration or subscription payment.General Comment-----It is amazing how many senior roles at the ADHA are being advertised it seem. Some at $150,000 plus!To keep busy we have vapourware interop plans being discussed and bullshit educational sessions being run for lesser salaries!Otherwise it has been a pretty boring week I have to say!-----https://www.ama.com.au/gpnn/issue-22-number-...
Source: Australian Health Information Technology - September 12, 2022 Category: Information Technology Authors: Dr David G More MB PhD Source Type: blogs

Weekly Overseas Health IT Links –3rd September, 2022.
Here are a few I came across last week.Note: Each link is followed by a title and few paragraphs. For the full article click on the link above title of the article. Note also that full access to some links may require site registration or subscription payment-----https://healthitanalytics.com/news/machine-learning-tools-predict-post-op-complications-surgery-durationMachine-Learning Tools Predict Post-Op Complications, Surgery DurationResearchers from Washington University in St. Louis have developed machine-learning tools that can predict post-operative complications and surgery duration using perioperative data.ByShania K...
Source: Australian Health Information Technology - September 3, 2022 Category: Information Technology Authors: Dr David G More MB PhD Source Type: blogs

Underfunding Research Of Female Health Leaves Huge Amounts Of Money On The Table
“Did you know that at least one-third of women have lower back pain before their periods every month, and yet, nobody seems to fully understand why?” – asked a Medical Futurist team member a little while ago. The question led to a discussion about the differences in research, funding and understanding of male-only and female-only health issues, and consequently, to this article. It is a well-known fact that some diseases or conditions dominantly affect one gender or the other. There are the trivial ones, like prostate cancer or ovarian, cervical, uterine cancers. But there is a long list of diseases and condit...
Source: The Medical Futurist - May 12, 2022 Category: Information Technology Authors: Andrea Koncz Tags: TMF Future of Medicine Healthcare Policy Medical Education women female health under-reseached gender gap in healthcare Source Type: blogs

Fight Aging! Newsletter, May 2nd 2022
In this study, we tested the therapeutic potential of VHHASC and a newly generated VHH against murine ASC (VHHmASC) to target ASC specks in vitro and in vivo. We show that pre-incubation of extracellular ASC specks with VHHASC abrogated their inflammatory functions in vitro. Recombinant VHHASC rapidly disassembled pre-formed ASC specks and thus inhibited their ability to seed the nucleation of soluble ASC. Notably, VHHASC required prior cytosolic access to prevent inflammasome activation within cells, but it was effective against extracellular ASC specks released following caspase-1-dependent loss of membrane integrity, an...
Source: Fight Aging! - May 1, 2022 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Towards Control of Inflammation as an Important Goal in the Treatment of Aging
Today I'll point out a review article that laments the present state of progress towards the control of inflammation in the human body. While acknowledging that great strides have been made in ways to interfere in inflammatory signaling, benefiting many patients, present tools are crude in comparison to the technologies that will most likely be needed in order to truly control unresolved, chronic inflammation and eliminate its contribution to age-related disease. True control of inflammation would imply the ability to (a) trigger resolution mechanisms with specificity, avoiding impairment of the operation of inflammation w...
Source: Fight Aging! - April 25, 2022 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs

How to Navigate Life with a Chronic Disease Like T1D and High-Deductible Insurance - Redux
Last February (2021), I wrote a blog post called " How to Navigate Life with a Chronic Disease Like T1D and High-Deductible Insurance Plans " (read my post athttps://blog.sstrumello.com/2021/02/how-to-navigate-life-with-chronic.html for details).I still stand by all of the recommendations I made in that blog post because I actually used (and still use some) the methods described effectively and saved a lot of money by doing so. But times change, and sometimes strategies need to evolve with changes that happen in the world around us.Intro of " Authorized Generic " Insulins, plus Branded/Unbranded BiosimilarsFor example, in ...
Source: Scott's Web Log - April 7, 2022 Category: Endocrinology Tags: 2022 high-deductible insurance plans insulin Source Type: blogs

Fight Aging! Newsletter, April 4th 2022
Fight Aging! publishes news and commentary relevant to the goal of ending all age-related disease, to be achieved by bringing the mechanisms of aging under the control of modern medicine. This weekly newsletter is sent to thousands of interested subscribers. To subscribe or unsubscribe from the newsletter, please visit: https://www.fightaging.org/newsletter/ Longevity Industry Consulting Services Reason, the founder of Fight Aging! and Repair Biotechnologies, offers strategic consulting services to investors, entrepreneurs, and others interested in the longevity industry and its complexities. To find out m...
Source: Fight Aging! - April 3, 2022 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Aging of the Intestinal Barrier as a Driving Cause of Chronic Inflammation
Chronic inflammation is a feature of aging, and causes disruption of cell and tissue function throughout the body. Short term inflammation is a necessary feature of regeneration from injury and defense against pathogens, but when inflammatory signaling is maintained for the long term it becomes very harmful. The risk of suffering all of the common diseases of aging is strongly connected to raised inflammation. Given this, we might ask what causes age-related systemic inflammation, and thus where should the research community seek to intervene, in order to reverse this undesirable aspect of degenerative aging. A grow...
Source: Fight Aging! - March 29, 2022 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs