Reduction of intracellular Mg < sup > 2+ < /sup > caused by reactive oxygen species in rat ventricular myocytes
Am J Physiol Cell Physiol. 2023 Mar 13. doi: 10.1152/ajpcell.00490.2022. Online ahead of print.ABSTRACTThe concentration of intracellular free Mg2+ ([Mg2+]i) should be maintained strictly for the regulation of cellular functions. Since reactive oxygen species (ROS) are liable to increase in various pathological conditions and induce cellular damage, we investigated whether ROS affect intracellular Mg2+ homeostasis. We measured [Mg2+]i in ventricular myocytes from Wistar rats using the fluorescent indicator, mag-fura-2. The administration of hydrogen peroxide (H2O2) decreased [Mg2+]iinCa2+-free Tyrode's solution. Intracellu...
Source: American Journal of Physiology. Cell Physiology - March 13, 2023 Category: Cytology Authors: Michiko Tashiro Masato Konishi Makino Watanabe Utako Yokoyama Source Type: research
Reduction of intracellular Mg < sup > 2+ < /sup > caused by reactive oxygen species in rat ventricular myocytes
Am J Physiol Cell Physiol. 2023 Mar 13. doi: 10.1152/ajpcell.00490.2022. Online ahead of print.ABSTRACTThe concentration of intracellular free Mg2+ ([Mg2+]i) should be maintained strictly for the regulation of cellular functions. Since reactive oxygen species (ROS) are liable to increase in various pathological conditions and induce cellular damage, we investigated whether ROS affect intracellular Mg2+ homeostasis. We measured [Mg2+]i in ventricular myocytes from Wistar rats using the fluorescent indicator, mag-fura-2. The administration of hydrogen peroxide (H2O2) decreased [Mg2+]iinCa2+-free Tyrode's solution. Intracellu...
Source: Am J Physiol Cell Ph... - March 13, 2023 Category: Cytology Authors: Michiko Tashiro Masato Konishi Makino Watanabe Utako Yokoyama Source Type: research
Reduction of intracellular Mg < sup > 2+ < /sup > caused by reactive oxygen species in rat ventricular myocytes
Am J Physiol Cell Physiol. 2023 Mar 13. doi: 10.1152/ajpcell.00490.2022. Online ahead of print.ABSTRACTThe concentration of intracellular free Mg2+ ([Mg2+]i) should be maintained strictly for the regulation of cellular functions. Since reactive oxygen species (ROS) are liable to increase in various pathological conditions and induce cellular damage, we investigated whether ROS affect intracellular Mg2+ homeostasis. We measured [Mg2+]i in ventricular myocytes from Wistar rats using the fluorescent indicator, mag-fura-2. The administration of hydrogen peroxide (H2O2) decreased [Mg2+]iinCa2+-free Tyrode's solution. Intracellu...
Source: American Journal of Physiology. Cell Physiology - March 13, 2023 Category: Cytology Authors: Michiko Tashiro Masato Konishi Makino Watanabe Utako Yokoyama Source Type: research
Reduction of intracellular Mg < sup > 2+ < /sup > caused by reactive oxygen species in rat ventricular myocytes
Am J Physiol Cell Physiol. 2023 Mar 13. doi: 10.1152/ajpcell.00490.2022. Online ahead of print.ABSTRACTThe concentration of intracellular free Mg2+ ([Mg2+]i) should be maintained strictly for the regulation of cellular functions. Since reactive oxygen species (ROS) are liable to increase in various pathological conditions and induce cellular damage, we investigated whether ROS affect intracellular Mg2+ homeostasis. We measured [Mg2+]i in ventricular myocytes from Wistar rats using the fluorescent indicator, mag-fura-2. The administration of hydrogen peroxide (H2O2) decreased [Mg2+]iinCa2+-free Tyrode's solution. Intracellu...
Source: Am J Physiol Cell Ph... - March 13, 2023 Category: Cytology Authors: Michiko Tashiro Masato Konishi Makino Watanabe Utako Yokoyama Source Type: research
Reduction of intracellular Mg < sup > 2+ < /sup > caused by reactive oxygen species in rat ventricular myocytes
Am J Physiol Cell Physiol. 2023 Mar 13. doi: 10.1152/ajpcell.00490.2022. Online ahead of print.ABSTRACTThe concentration of intracellular free Mg2+ ([Mg2+]i) should be maintained strictly for the regulation of cellular functions. Since reactive oxygen species (ROS) are liable to increase in various pathological conditions and induce cellular damage, we investigated whether ROS affect intracellular Mg2+ homeostasis. We measured [Mg2+]i in ventricular myocytes from Wistar rats using the fluorescent indicator, mag-fura-2. The administration of hydrogen peroxide (H2O2) decreased [Mg2+]iinCa2+-free Tyrode's solution. Intracellu...
Source: American Journal of Physiology. Cell Physiology - March 13, 2023 Category: Cytology Authors: Michiko Tashiro Masato Konishi Makino Watanabe Utako Yokoyama Source Type: research
Reduction of intracellular Mg < sup > 2+ < /sup > caused by reactive oxygen species in rat ventricular myocytes
Am J Physiol Cell Physiol. 2023 Mar 13. doi: 10.1152/ajpcell.00490.2022. Online ahead of print.ABSTRACTThe concentration of intracellular free Mg2+ ([Mg2+]i) should be maintained strictly for the regulation of cellular functions. Since reactive oxygen species (ROS) are liable to increase in various pathological conditions and induce cellular damage, we investigated whether ROS affect intracellular Mg2+ homeostasis. We measured [Mg2+]i in ventricular myocytes from Wistar rats using the fluorescent indicator, mag-fura-2. The administration of hydrogen peroxide (H2O2) decreased [Mg2+]iinCa2+-free Tyrode's solution. Intracellu...
Source: Am J Physiol Cell Ph... - March 13, 2023 Category: Cytology Authors: Michiko Tashiro Masato Konishi Makino Watanabe Utako Yokoyama Source Type: research
Reduction of intracellular Mg < sup > 2+ < /sup > caused by reactive oxygen species in rat ventricular myocytes
Am J Physiol Cell Physiol. 2023 Mar 13. doi: 10.1152/ajpcell.00490.2022. Online ahead of print.ABSTRACTThe concentration of intracellular free Mg2+ ([Mg2+]i) should be maintained strictly for the regulation of cellular functions. Since reactive oxygen species (ROS) are liable to increase in various pathological conditions and induce cellular damage, we investigated whether ROS affect intracellular Mg2+ homeostasis. We measured [Mg2+]i in ventricular myocytes from Wistar rats using the fluorescent indicator, mag-fura-2. The administration of hydrogen peroxide (H2O2) decreased [Mg2+]iinCa2+-free Tyrode's solution. Intracellu...
Source: American Journal of Physiology. Cell Physiology - March 13, 2023 Category: Cytology Authors: Michiko Tashiro Masato Konishi Makino Watanabe Utako Yokoyama Source Type: research
Reduction of intracellular Mg < sup > 2+ < /sup > caused by reactive oxygen species in rat ventricular myocytes
Am J Physiol Cell Physiol. 2023 Mar 13. doi: 10.1152/ajpcell.00490.2022. Online ahead of print.ABSTRACTThe concentration of intracellular free Mg2+ ([Mg2+]i) should be maintained strictly for the regulation of cellular functions. Since reactive oxygen species (ROS) are liable to increase in various pathological conditions and induce cellular damage, we investigated whether ROS affect intracellular Mg2+ homeostasis. We measured [Mg2+]i in ventricular myocytes from Wistar rats using the fluorescent indicator, mag-fura-2. The administration of hydrogen peroxide (H2O2) decreased [Mg2+]iinCa2+-free Tyrode's solution. Intracellu...
Source: Am J Physiol Cell Ph... - March 13, 2023 Category: Cytology Authors: Michiko Tashiro Masato Konishi Makino Watanabe Utako Yokoyama Source Type: research
Reduction of intracellular Mg < sup > 2+ < /sup > caused by reactive oxygen species in rat ventricular myocytes
Am J Physiol Cell Physiol. 2023 Mar 13. doi: 10.1152/ajpcell.00490.2022. Online ahead of print.ABSTRACTThe concentration of intracellular free Mg2+ ([Mg2+]i) should be maintained strictly for the regulation of cellular functions. Since reactive oxygen species (ROS) are liable to increase in various pathological conditions and induce cellular damage, we investigated whether ROS affect intracellular Mg2+ homeostasis. We measured [Mg2+]i in ventricular myocytes from Wistar rats using the fluorescent indicator, mag-fura-2. The administration of hydrogen peroxide (H2O2) decreased [Mg2+]iinCa2+-free Tyrode's solution. Intracellu...
Source: American Journal of Physiology. Cell Physiology - March 13, 2023 Category: Cytology Authors: Michiko Tashiro Masato Konishi Makino Watanabe Utako Yokoyama Source Type: research
Anticancer Effects of Antidepressants in Hepatocellular Carcinoma Cells
CONCLUSION: According to previous and present findings, TCAs, SSRIs and mianserin may have anti-tumor activity in HCC. However, the appropriate dose, frequency, and route of the administration still need to be determined in future preclinical and clinical studies.PMID:36854516 | DOI:10.21873/anticanres.16266 (Source: Cell Research)
Source: Cell Research - February 28, 2023 Category: Cytology Authors: Ya-Hui Huang Chau-Ting Yeh Source Type: research
Neuromodulating agents in functional dyspepsia: a comprehensive review
CONCLUSION: Selected neuromodulators have an established efficacy in functional dyspepsia. The best supporting evidence is available for TCAs with a potential role for tetracyclic antidepressants, levosulpiride and anxiolytics.PMID:36842175 | DOI:10.51821/86.1.10998 (Source: Acta Gastro-Enterologica Belgica)
Source: Acta Gastro-Enterologica Belgica - February 26, 2023 Category: Gastroenterology Authors: L Bosman L Wauters T Vanuytsel Source Type: research
