Impact of Passive Therapeutic Hypothermia for Neonatal Asphyxia in a Developing Country
(Source: Indian Journal of Pediatrics)
Source: Indian Journal of Pediatrics - April 12, 2024 Category: Pediatrics Source Type: research
Changes in temperature in preheated crystalloids at ambient temperatures relevant to a prehospital setting: an experimental simulation study with the application of prehospital treatment of trauma patients suffering from accidental hypothermia
Accidental hypothermia is common in all trauma patients and contributes to the lethal diamond, increasing both morbidity and mortality. In hypotensive shock, fluid resuscitation is recommended using fluids wit... (Source: BMC Emergency Medicine)
Source: BMC Emergency Medicine - April 12, 2024 Category: Emergency Medicine Authors: Emil Jensen, Helena Rentzhog, Johan Herlitz, Christer Axelsson and Peter Lundgren Tags: Research Source Type: research
Effect of RARC-ERAS nursing program on clinical outcomes in patients undergoing RARC surgery: a retrospective, propensity matching study
J Robot Surg. 2024 Apr 10;18(1):170. doi: 10.1007/s11701-024-01931-9.ABSTRACTCurrently, there is no specific perioperative nursing standard for RARC based on the ERAS concept. This retrospective study investigates to analyze the effect of RARC-ERAS nursing program on VTE and other clinical outcomes in patients undergoing RARC surgery. This retrospective study included 216 patients undergoing RARC surgery From January 1, 2022 to December 30, 2023, and propensity score adjustment analysis was applied. The study compares a control group receiving traditional nursing and an observation group receiving RARC-ERAS nursing program...
Source: Cancer Control - April 10, 2024 Category: Cancer & Oncology Authors: Mang-Mang He Zhen-Feng Zhou Xiao-Fen Yu Chun-Cong Zhou Source Type: research
Effect of RARC-ERAS nursing program on clinical outcomes in patients undergoing RARC surgery: a retrospective, propensity matching study
AbstractCurrently, there is no specific perioperative nursing standard for RARC based on the ERAS concept. This retrospective study investigates to analyze the effect of RARC-ERAS nursing program on VTE and other clinical outcomes in patients undergoing RARC surgery. This retrospective study included 216 patients undergoing RARC surgery From January 1, 2022 to December 30, 2023, and propensity score adjustment analysis was applied. The study compares a control group receiving traditional nursing and an observation group receiving RARC-ERAS nursing program. Perioperative variables and other postoperative complications were ...
Source: Journal of Robotic Surgery - April 10, 2024 Category: Surgery Source Type: research
An untargeted metabolomics approach to study changes of the medium during human cornea culture
ConclusionThe results revealed a valuable untargeted metabolomics approach which can be applied in organ culture metabolomics. (Source: Metabolomics)
Source: Metabolomics - April 6, 2024 Category: Biology Source Type: research
Hypothermia effects on neuronal plasticity post spinal cord injury
ConclusionOur results show that the forelimbs SSEP signals from the two groups of injuries with and without hypothermia have statistically significant differences on days 4 and 7. This indicates the neuroprotective effect of early hypothermia and its influences on stimulating further the neuroplasticity within the upper limbs neural network post-SCI. Timely detection of neuroplasticity and identifying the endogenous and exogenous factors have clinical applications in planning a more effective rehabilitation and functional electrical stimulation (FES) interventions in SCI patients. (Source: PLoS One)
Source: PLoS One - April 5, 2024 Category: Biomedical Science Authors: Hasan Al-Nashash Source Type: research
Good outcome prediction after out-of-hospital cardiac arrest: a prospective multicenter observational study in Korea (the KORHN-PRO registry)
To assess the ability of clinical examination, biomarkers, electrophysiology and brain imaging, individually or in combination to predict good neurological outcomes at 6 months after CA. (Source: Resuscitation)
Source: Resuscitation - April 4, 2024 Category: Emergency Medicine Authors: Hyo Jin Bang, Chun Song Youn, Claudio Sandroni, Kyu Nam Park, Byung Kook Lee, Sang Hoon Oh, In Soo Cho, Seung Pill Choi, on behalf of the Korean Hypothermia Network Investigators Tags: Clinical paper Source Type: research
Mild Therapeutic Hypothermia Alleviated Myocardial Ischemia/Reperfusion Injury via Targeting SLC25A10 to Suppress Mitochondrial Apoptosis
J Cardiovasc Transl Res. 2024 Apr 3. doi: 10.1007/s12265-024-10503-z. Online ahead of print.ABSTRACTMyocardial ischemia/reperfusion injury (MI/RI) is identified as a severe vascular emergency, and the treatment strategy of MI/RI still needs further improvement. The present study aimed to investigate the potential effects of mild therapeutic hypothermia (MTH) on MI/RI and underlying mechanisms. In ischemia/reperfusion (I/R) rats, MTH treatment significantly improved myocardial injury, attenuated myocardial infarction, and inhibited the mitochondrial apoptosis pathway. The results of proteomics identified SLC25A10 as the mai...
Source: Cell Research - April 3, 2024 Category: Cytology Authors: Senlin Ma Yun Song Yanxin Xu Chao Wang Yifan Yang Yanchao Zheng Qiuxin Lu Qingjiang Chen Jian Wu Bin Wang Mingquan Chen Source Type: research
Umbilical artery eucapnic pH to assess fetal well being
Umbilical artery gas results help obstetricians to assess fetal well being during the course of labor and guide screening decisions on eligibility for therapeutic hypothermia or also know as whole body or head cooling. The accuracy of results, especially base deficit on arterial cord gas analysis, in predicting brain injury is questioned. A novel biomarker specifically calculated for fetal acid-base physiology and response to asphyxia —neonatal eucapnic pH as a marker of neonatal metabolic acidosis—has the potential to be an accurate predictor of hypoxic-ischemic encephalopathy. (Source: American Journal of Obstetrics and Gynecology)
Source: American Journal of Obstetrics and Gynecology - April 3, 2024 Category: OBGYN Authors: Thierry Daboval, Paul Ouellet, Amr El Shahed, Linh Ly, Caroline Ahearne, Claude Racinet Tags: Original Research: Obstetrics Source Type: research
Mild Therapeutic Hypothermia Alleviated Myocardial Ischemia/Reperfusion Injury via Targeting SLC25A10 to Suppress Mitochondrial Apoptosis
AbstractMyocardial ischemia/reperfusion injury (MI/RI) is identified as a severe vascular emergency, and the treatment strategy of MI/RI still needs further improvement. The present study aimed to investigate the potential effects of mild therapeutic hypothermia (MTH) on MI/RI and underlying mechanisms. In ischemia/reperfusion (I/R) rats, MTH treatment significantly improved myocardial injury, attenuated myocardial infarction, and inhibited the mitochondrial apoptosis pathway. The results of proteomics identified SLC25A10 as the main target of MTH treatment. Consistently, SLC25A10 expressions in I/R rat myocardium and hypo...
Source: Journal of Cardiovascular Translational Research - April 3, 2024 Category: Cardiology Source Type: research
Umbilical artery eucapnic pH to assess fetal well-being
Umbilical artery gas results help obstetricians assess fetal well-being during labor and guide screening decisions on eligibility for therapeutic hypothermia (ie, whole-body or head cooling). The accuracy of results, especially for the base deficit on arterial cord gas analysis, in predicting brain injury is questioned. A novel biomarker specifically calculated for fetal acid-base physiology and response to asphyxia —neonatal eucapnic pH as a marker of neonatal metabolic acidosis—has the potential to be an accurate predictor of hypoxic-ischemic encephalopathy. (Source: American Journal of Obstetrics and Gynecology)
Source: American Journal of Obstetrics and Gynecology - April 3, 2024 Category: OBGYN Authors: Thierry Daboval, Paul Ouellet, Amr El Shahed, Linh Ly, Caroline Ahearne, Claude Racinet Tags: Original Research Source Type: research
Risk factors for infection and outcomes in infants with neonatal encephalopathy: a cohort study
CONCLUSIONS: Infants with NE exposed to risk factors for early-onset infection did not have worse short-term adverse outcomes.IMPACT: Risk factors for early-onset neonatal infection, including rupture of membranes >18 h, maternal group B streptococcus colonization, chorioamnionitis, maternal pyrexia or antepartum antibiotics, were not associated with death or short-term morbidity after cooling for NE. Despite exposure to risk factors for early-onset neonatal infection, infants with NE reached oral feeds earlier and needed fewer anti-seizure medications for a shorter duration than infants with NE but without such risk fa...
Source: Pediatric Research - April 2, 2024 Category: Pediatrics Authors: David Odd Hemmen Sabir Simon A Jones Chris Gale Ela Chakkarapani Source Type: research
Impact of therapeutic hypothermia (TH) on echocardiography indices of pulmonary hemodynamics among neonates with hypoxic ischemic encephalopathy (HIE)
Journal of Perinatology, Published online: 02 April 2024; doi:10.1038/s41372-024-01958-8Impact of therapeutic hypothermia (TH) on echocardiography indices of pulmonary hemodynamics among neonates with hypoxic ischemic encephalopathy (HIE) (Source: Journal of Perinatology)
Source: Journal of Perinatology - April 2, 2024 Category: Perinatology & Neonatology Authors: Angelica M. Vasquez Adrianne R. Bischoff Regan E. Giesinger Patrick J. McNamara Source Type: research
