Planned complex suicide involving combined drug intoxication and femoral catheterization
J Forensic Sci. 2021 Jul 22. doi: 10.1111/1556-4029.14809. Online ahead of print.ABSTRACTComplex planned suicide is characterized by the simultaneous use of two or more methods to ensure that death occurs even if one method fails. The authors present an original combination of two self-killing methods. A 42-year-old cardiologist, with a major depressive syndrome and several suicide attempts, as well as cocaine addiction, was found dead at his home with a femoral catheter inserted in the right femoral artery. The autopsy concluded that death was due to major hemorrhagic process in a context of suicide. Toxicological analyse...
Source: Journal of Forensic Sciences - July 22, 2021 Category: Forensic Medicine Authors: Anne-Laure P élissier-Alicot Marc Deveaux Caroline Sastre Valerie Baillif-Couniou Marie-Amandine Christia Chantal Champeaux-Fesquet Georges Leonetti Source Type: research
Planned complex suicide involving combined drug intoxication and femoral catheterization
J Forensic Sci. 2021 Jul 22. doi: 10.1111/1556-4029.14809. Online ahead of print.ABSTRACTComplex planned suicide is characterized by the simultaneous use of two or more methods to ensure that death occurs even if one method fails. The authors present an original combination of two self-killing methods. A 42-year-old cardiologist, with a major depressive syndrome and several suicide attempts, as well as cocaine addiction, was found dead at his home with a femoral catheter inserted in the right femoral artery. The autopsy concluded that death was due to major hemorrhagic process in a context of suicide. Toxicological analyse...
Source: Journal of Forensic Sciences - July 22, 2021 Category: Forensic Medicine Authors: Anne-Laure P élissier-Alicot Marc Deveaux Caroline Sastre Valerie Baillif-Couniou Marie-Amandine Christia Chantal Champeaux-Fesquet Georges Leonetti Source Type: research
The histamine H < sub > 1 < /sub > receptor antagonist hydroxyzine enhances sevoflurane and propofol anesthesia: A quantitative EEG study
CONCLUSIONS: Hydroxyzine enhances both sevoflurane anesthesia and propofol anesthesia probably by facilitation of GABAergic neural circuit mechanisms.SIGNIFICANCE: The findings provide a new insight into the role of histaminergic neurons during general anesthesia in humans.PMID:34284240 | DOI:10.1016/j.clinph.2021.05.024 (Source: Clinical Neurophysiology)
Source: Clinical Neurophysiology - July 20, 2021 Category: Neurology Authors: Ryusuke Tanaka Satoshi Tanaka Kazuko Hayashi Keisuke Iida Teiji Sawa Mikito Kawamata Source Type: research
The histamine H < sub > 1 < /sub > receptor antagonist hydroxyzine enhances sevoflurane and propofol anesthesia: A quantitative EEG study
CONCLUSIONS: Hydroxyzine enhances both sevoflurane anesthesia and propofol anesthesia probably by facilitation of GABAergic neural circuit mechanisms.SIGNIFICANCE: The findings provide a new insight into the role of histaminergic neurons during general anesthesia in humans.PMID:34284240 | DOI:10.1016/j.clinph.2021.05.024 (Source: Clinical Neurophysiology)
Source: Clinical Neurophysiology - July 20, 2021 Category: Neurology Authors: Ryusuke Tanaka Satoshi Tanaka Kazuko Hayashi Keisuke Iida Teiji Sawa Mikito Kawamata Source Type: research
Concerning the article: “Oral sedation in dentistry: evaluation of professional practice of oral hydroxyzine in the University Hospital of Rennes, France” that appeared in the European Archives of Paediatric Dentistry. 2021 Apr 11. doi: 10.1007/s40368-021-00620-7. Online ahead of print
(Source: European Archives of Paediatric Dentistry)
Source: European Archives of Paediatric Dentistry - June 15, 2021 Category: Dentistry Source Type: research
Wireless electroencephalography (EEG) to monitor sleep among patients being withdrawn from opioids: Evidence of feasibility and utility.
Experimental and Clinical Psychopharmacology, Vol 30(6), Dec 2022, 1016-1023; doi:10.1037/pha0000483Sleep impairment is a common comorbid and debilitating symptom for persons with opioid use disorder (OUD). Research into underlying mechanisms and efficacious treatment interventions for OUD-related sleep problems requires both precise and physiologic measurements of sleep-related outcomes and impairment. This pilot examined the feasibility of a wireless sleep electroencephalography (EEG) monitor (Sleep Profiler™) to measure sleep outcomes and architecture among participants undergoing supervised opioid withdrawal. Sleep o...
Source: Experimental and Clinical Psychopharmacology - June 7, 2021 Category: Psychiatry & Psychology Source Type: research
How our treatment of asthma has changed over the last half century
At the close of the 1960s asthma treatment was quite simple. For chronic maintenance treatment there were tablets containing the sympathomimetic ephedrine, the methylxanthine theophylline, a barbiturate or hydroxyzine to offset the stimulatory side effects of ephedrine and in some preparations an expectorant. Other chronic medications included the expectorants iodine and glyceryl guaiacolate administered singly, the oral corticosteroids prednisone and methyl prednisolone, and the long acting inhaled steroid dexamethasone, which was fully active systemically. (Source: Annals of Allergy, Asthma and Immunology)
Source: Annals of Allergy, Asthma and Immunology - May 19, 2021 Category: Allergy & Immunology Authors: Harold S Nelson Source Type: research
How our treatment of asthma has changed in the last half century
At the close of the 1960s, asthma treatment was quite simple. For chronic maintenance treatment, there were tablets containing the sympathomimetic ephedrine, the methylxanthine theophylline, a barbiturate or hydroxyzine to offset the stimulatory adverse effects of ephedrine, and in some preparations an expectorant. Other chronic medications included the expectorants iodine and glyceryl guaiacolate administered singly, the oral corticosteroids prednisone and methyl prednisolone, and the long-acting inhaled steroid dexamethasone, which was fully active systemically. (Source: Annals of Allergy, Asthma and Immunology)
Source: Annals of Allergy, Asthma and Immunology - May 19, 2021 Category: Allergy & Immunology Authors: Harold S. Nelson Tags: Perspective Source Type: research
Hydroxyzine-induced Torsade de Pointes in a Patient with Complete Atrioventricular Block
Intern Med. 2021 Apr 26. doi: 10.2169/internalmedicine.7382-21. Online ahead of print.ABSTRACTAn 82-year-old woman was admitted to our hospital because of dyspnea and bradycardia during exertion. Electrocardiography revealed complete atrioventricular block. During pacemaker implantation, a small dose (12.5 mg) of hydroxyzine was injected for sedation, and torsade de pointes (Tdp) occurred. The QT interval was prolonged after administration of hydroxyzine, and Tdp was observed after the R on T phenomenon occurred, indicating that hydroxyzine was capable of prolonging the QT interval and causing Tdp. Therefore, we must be ca...
Source: Internal Medicine - April 26, 2021 Category: Internal Medicine Authors: Kaito Koshino Akihiro Endo Nobuhide Watanabe Koichi Okazaki Kazuaki Tanabe Source Type: research
