Hydrocephalus Research This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Deep learning-based quantification of total bleeding volume and its association with complications, disability, and death in patients with aneurysmal subarachnoid hemorrhage
CONCLUSIONS: Elevated TBV is associated with a greater risk of hydrocephalus, rebleeding, death, and poor prognosis.PMID:38552240 | DOI:10.3171/2024.1.JNS232280 (Source: Journal of Neurosurgery)
Source: Journal of Neurosurgery - March 29, 2024 Category: Neurosurgery Authors: Ping Hu Yanze Wu Tengfeng Yan Lei Shu Feng Liu Bing Xiao Minhua Ye Miaojing Wu Shigang Lv Xingen Zhu Source Type: research

Trastuzumab deruxtecan in patients with metastatic non-small-cell lung cancer (DESTINY-Lung01): primary results of the HER2-overexpressing cohorts from a single-arm, phase 2 trial
Lancet Oncol. 2024 Apr;25(4):439-454. doi: 10.1016/S1470-2045(24)00064-0.ABSTRACTBACKGROUND: DESTINY-Lung01 is a multicentre, open-label, phase 2 study evaluating the antitumour activity and safety of trastuzumab deruxtecan, a HER2-directed antibody-drug conjugate, in patients with HER2-overexpressing or HER2 (ERBB2)-mutant unresectable or metastatic non-small-cell lung cancer (NSCLC). The results of the HER2-mutant cohort (cohort 2) have been reported elsewhere. Herein, we report the primary analysis of cohorts 1 and 1A, which aimed to evaluate the activity and safety of trastuzumab deruxtecan 5·4 mg/kg and 6·4 mg/kg in...
Source: Ann Oncol - March 28, 2024 Category: Cancer & Oncology Authors: Egbert F Smit Enriqueta Felip Dipesh Uprety Misako Nagasaka Kazuhiko Nakagawa Luis Paz-Ares Rodr íguez Jose M Pacheco Bob T Li David Planchard Christina Baik Yasushi Goto Haruyasu Murakami Andreas Saltos Kaline Pereira Ayumi Taguchi Yingkai Cheng Qi Yan Source Type: research

Autonomic dysfunction in patients with tectal plate compression: A systematic review
CONCLUSIONS: Though these lesions are most characterized by Parinaud's syndrome and hydrocephalus, this review suggests dysfunction of the autonomic nervous system may be at play and require consideration at initial presentation and treatment.PMID:38547628 | DOI:10.1016/j.clineuro.2024.108247 (Source: The Medical Clinics of North America)
Source: The Medical Clinics of North America - March 28, 2024 Category: General Medicine Authors: Sarah E Renberg Caren M Stuebe Carolyn Quinsey Source Type: research

Safety and efficacy of magnesium-rich artificial cerebrospinal fluid for subarachnoid hemorrhage
ConclusionUsing MACSF as an irrigation fluid for aneurysm clipping can significantly improve the 90-day prognosis of patients with aSAH, which may be related to the reduced incidence of CVS.Clinical trial registrationhttps://www.clinicaltrials.gov, identifier NCT04358445. (Source: Frontiers in Neurology)
Source: Frontiers in Neurology - March 28, 2024 Category: Neurology Source Type: research

Sudden death unmasking a Chiari I malformation with occult chronic hydrocephalus
Neurochirurgie. 2024 Mar 25;70(4):101554. doi: 10.1016/j.neuchi.2024.101554. Online ahead of print.NO ABSTRACTPMID:38531209 | DOI:10.1016/j.neuchi.2024.101554 (Source: Neuro-Chirurgie)
Source: Neuro-Chirurgie - March 26, 2024 Category: Neurosurgery Authors: Charles Champeaux Depond Andr éi Birladeanu Dahmane Elhairech Philippe Metellus Source Type: research

Sudden death unmasking a Chiari I malformation with occult chronic hydrocephalus
Neurochirurgie. 2024 Mar 25;70(4):101554. doi: 10.1016/j.neuchi.2024.101554. Online ahead of print.NO ABSTRACTPMID:38531209 | DOI:10.1016/j.neuchi.2024.101554 (Source: Neurochirurgie)
Source: Neurochirurgie - March 26, 2024 Category: Neurosurgery Authors: Charles Champeaux Depond Andr éi Birladeanu Dahmane Elhairech Philippe Metellus Source Type: research

Microcirculatory Impairment and Cerebral Injury in Hydrocephalus and the Effects of Cerebrospinal Fluid Diversion
CONCLUSION: Rapid ventricular dilatation is associated with severe microvascular distortion, vascular regression, cortical hypoperfusion, and cellular changes that impair the recovery of CBF and motor function after CSF release. Moreover, CSF release may induce reperfusion injury. This pathophysiology should be taken into account when treating hydrocephalus.PMID:38511941 | DOI:10.1227/neu.0000000000002908 (Source: Cancer Control)
Source: Cancer Control - March 21, 2024 Category: Cancer & Oncology Authors: Kuo-Wei Chen Yong-Ren Chen Ling-Yu Yang Ya-Wen Cheng Sheng-Che Chou Yi-Hsing Chen Yi-Tzu Chen Sung-Tsang Hsieh Meng-Fai Kuo Kuo-Chuan Wang Source Type: research

Structural neuroimaging markers of normal pressure hydrocephalus versus Alzheimer ’s dementia and Parkinson’s disease, and hydrocephalus versus atrophy in chronic TBI—a narrative review
ConclusionAlong with an up-to-date literature review on the structural neurodegeneration due to NPH versus AD/PD, and hydrocephalus versus atrophy in cTBI, this article sheds light on the potential of structural imaging markers as (differential) diagnostic aids for the timely recognition of patients with reversible (normal pressure) hydrocephalus, and opportunities to develop computational tools for their objective assessment. (Source: Frontiers in Neurology)
Source: Frontiers in Neurology - March 21, 2024 Category: Neurology Source Type: research

Early prediction of ventricular peritoneal shunt dependency in aneurysmal subarachnoid haemorrhage patients by recurrent neural network-based machine learning using routine intensive care unit data
AbstractAneurysmal subarachnoid haemorrhage (aSAH) can lead to complications such as acute hydrocephalic congestion. Treatment of this acute condition often includes establishing an external ventricular drainage (EVD). However, chronic hydrocephalus develops in some patients, who then require placement of a permanent ventriculoperitoneal (VP) shunt. The aim of this study was to employ recurrent neural network (RNN)-based machine learning techniques to identify patients who require VP shunt placement at an early stage. This retrospective single-centre study included all patients who were diagnosed with aSAH and treated in t...
Source: Journal of Clinical Monitoring and Computing - March 21, 2024 Category: Information Technology Source Type: research