Quantitative noninvasive measurement of cerebrospinal fluid flow in shunted hydrocephalus
CONCLUSIONS: The PC-MRI sequence provided accurate and reliable clinical measurements of CSF flow in shunt-treated patients. This work provides the necessary framework to include PC-MRI as an immediate addition to the clinical setting in the noninvasive evaluation of shunt function and in future clinical investigations of CSF physiology.PMID:38564811 | DOI:10.3171/2023.7.JNS231326 (Source: Journal of Neurosurgery)
Source: Journal of Neurosurgery - April 2, 2024 Category: Neurosurgery Authors: Joseph H Ha Matthew T Borzage Erik B Vanstrum Eamon K Doyle Meenakshi Upreti Benita Tamrazi Marvin Nelson Stefan Bl üml Malkiat S Johal J Gordon McComb Jason Chu Susan Durham Mark D Krieger Rex A Moats Peter A Chiarelli Source Type: research

Risk Analysis Index as a preoperative frailty tool for elective ventriculoperitoneal shunt surgery for idiopathic normal pressure hydrocephalus
CONCLUSIONS: In a nationwide database analysis, increasing frailty, as measured by RAI, was associated with NHD, 30-day mortality, unplanned readmission, eLOS, and postoperative complications. Although the RAI outperformed the mFI-5, it is essential to account for the potentially reversible clinical issues related to the underlying disease process, as these factors may inflate frailty scores, assign undue risk, and diminish their utility. This knowledge may enhance provider understanding of the impact of frailty on postoperative outcomes for patients with iNPH, while highlighting the potential constraints associated with f...
Source: Journal of Neurosurgery - April 2, 2024 Category: Neurosurgery Authors: Evan Courville Kavelin Rumalla Syed Faraz Kazim Alis J Dicpinigaitis Meic Schmidt Timothy M Robinson Christian A Bowers Source Type: research

Quantitative noninvasive measurement of cerebrospinal fluid flow in shunted hydrocephalus
CONCLUSIONS: The PC-MRI sequence provided accurate and reliable clinical measurements of CSF flow in shunt-treated patients. This work provides the necessary framework to include PC-MRI as an immediate addition to the clinical setting in the noninvasive evaluation of shunt function and in future clinical investigations of CSF physiology.PMID:38564811 | DOI:10.3171/2023.7.JNS231326 (Source: Journal of Neurosurgery)
Source: Journal of Neurosurgery - April 2, 2024 Category: Neurosurgery Authors: Joseph H Ha Matthew T Borzage Erik B Vanstrum Eamon K Doyle Meenakshi Upreti Benita Tamrazi Marvin Nelson Stefan Bl üml Malkiat S Johal J Gordon McComb Jason Chu Susan Durham Mark D Krieger Rex A Moats Peter A Chiarelli Source Type: research

Risk Analysis Index as a preoperative frailty tool for elective ventriculoperitoneal shunt surgery for idiopathic normal pressure hydrocephalus
CONCLUSIONS: In a nationwide database analysis, increasing frailty, as measured by RAI, was associated with NHD, 30-day mortality, unplanned readmission, eLOS, and postoperative complications. Although the RAI outperformed the mFI-5, it is essential to account for the potentially reversible clinical issues related to the underlying disease process, as these factors may inflate frailty scores, assign undue risk, and diminish their utility. This knowledge may enhance provider understanding of the impact of frailty on postoperative outcomes for patients with iNPH, while highlighting the potential constraints associated with f...
Source: Journal of Neurosurgery - April 2, 2024 Category: Neurosurgery Authors: Evan Courville Kavelin Rumalla Syed Faraz Kazim Alis J Dicpinigaitis Meic Schmidt Timothy M Robinson Christian A Bowers Source Type: research

Quantitative noninvasive measurement of cerebrospinal fluid flow in shunted hydrocephalus
CONCLUSIONS: The PC-MRI sequence provided accurate and reliable clinical measurements of CSF flow in shunt-treated patients. This work provides the necessary framework to include PC-MRI as an immediate addition to the clinical setting in the noninvasive evaluation of shunt function and in future clinical investigations of CSF physiology.PMID:38564811 | DOI:10.3171/2023.7.JNS231326 (Source: Journal of Neurosurgery)
Source: Journal of Neurosurgery - April 2, 2024 Category: Neurosurgery Authors: Joseph H Ha Matthew T Borzage Erik B Vanstrum Eamon K Doyle Meenakshi Upreti Benita Tamrazi Marvin Nelson Stefan Bl üml Malkiat S Johal J Gordon McComb Jason Chu Susan Durham Mark D Krieger Rex A Moats Peter A Chiarelli Source Type: research

Risk Analysis Index as a preoperative frailty tool for elective ventriculoperitoneal shunt surgery for idiopathic normal pressure hydrocephalus
CONCLUSIONS: In a nationwide database analysis, increasing frailty, as measured by RAI, was associated with NHD, 30-day mortality, unplanned readmission, eLOS, and postoperative complications. Although the RAI outperformed the mFI-5, it is essential to account for the potentially reversible clinical issues related to the underlying disease process, as these factors may inflate frailty scores, assign undue risk, and diminish their utility. This knowledge may enhance provider understanding of the impact of frailty on postoperative outcomes for patients with iNPH, while highlighting the potential constraints associated with f...
Source: Journal of Neurosurgery - April 2, 2024 Category: Neurosurgery Authors: Evan Courville Kavelin Rumalla Syed Faraz Kazim Alis J Dicpinigaitis Meic Schmidt Timothy M Robinson Christian A Bowers Source Type: research

Predicting post-surgical outcomes in idiopathic normal pressure hydrocephalus using clinically important changes from the cerebrospinal fluid tap test
Patients diagnosed with idiopathic Normal Pressure Hydrocephalus (iNPH) typically experience symptom improvements after undergoing a cerebrospinal fluid-tap test (CSF-TT), These improvements are recognized as indicative of potential improvements following surgical intervention. As gait disturbance is the most common iNPH symptom, gait improvements are of predominant interest. The purpose of this study was to examine if clinically important changes in gait and balance from CSF-TT predict meaningful changes following surgery. (Source: Journal of the Neurological Sciences)
Source: Journal of the Neurological Sciences - April 1, 2024 Category: Neurology Authors: Ryan M. Gallagher, Jodie L. Marquez, Shabnam Dal, Peter G. Osmotherly Source Type: research

Pathogenesis and management of low-pressure hydrocephalus: A narrative review
Patients diagnosed with low-pressure hydrocephalus typically present with enlarged ventricles and unusually low intracranial pressure, often measuring below 5 cmH2O or even below atmospheric pressure. This atypical presentation often leads to low recognition and diagnostic rates. The development of low-pressure hydrocephalus is believed to be associated with a decrease in the viscoelasticity of brain tissue or separation between the ventricular and subarachnoid spaces. Risk factors for low-pressure hydrocephalus include subarachnoid hemorrhage, aqueduct stenosis, prior cranial radiotherapy , ventricular shunting, and cer...
Source: Journal of the Neurological Sciences - April 1, 2024 Category: Neurology Authors: Shanshan Duan, Jin Hu Tags: Review Article Source Type: research

Antidiuretic hormone deficiency secondary to inactive hydrocephalus: a case report
ConclusionsCentral diabetes insipidus due to hydrocephalus, though rare, can have serious complications including the predilection to develop a deficit of other pituitary hormones. Thus, even if hydrocephalus is dormant with normal intracranial pressure, it must be addressed during investigations of central diabetes insipidus. (Source: Journal of Medical Case Reports)
Source: Journal of Medical Case Reports - March 31, 2024 Category: General Medicine Source Type: research

Deep learning-based quantification of total bleeding volume and its association with complications, disability, and death in patients with aneurysmal subarachnoid hemorrhage
CONCLUSIONS: Elevated TBV is associated with a greater risk of hydrocephalus, rebleeding, death, and poor prognosis.PMID:38552240 | DOI:10.3171/2024.1.JNS232280 (Source: Journal of Neurosurgery)
Source: Journal of Neurosurgery - March 29, 2024 Category: Neurosurgery Authors: Ping Hu Yanze Wu Tengfeng Yan Lei Shu Feng Liu Bing Xiao Minhua Ye Miaojing Wu Shigang Lv Xingen Zhu Source Type: research

Deep learning-based quantification of total bleeding volume and its association with complications, disability, and death in patients with aneurysmal subarachnoid hemorrhage
CONCLUSIONS: Elevated TBV is associated with a greater risk of hydrocephalus, rebleeding, death, and poor prognosis.PMID:38552240 | DOI:10.3171/2024.1.JNS232280 (Source: Journal of Neurosurgery)
Source: Journal of Neurosurgery - March 29, 2024 Category: Neurosurgery Authors: Ping Hu Yanze Wu Tengfeng Yan Lei Shu Feng Liu Bing Xiao Minhua Ye Miaojing Wu Shigang Lv Xingen Zhu Source Type: research

Deep learning-based quantification of total bleeding volume and its association with complications, disability, and death in patients with aneurysmal subarachnoid hemorrhage
CONCLUSIONS: Elevated TBV is associated with a greater risk of hydrocephalus, rebleeding, death, and poor prognosis.PMID:38552240 | DOI:10.3171/2024.1.JNS232280 (Source: Journal of Neurosurgery)
Source: Journal of Neurosurgery - March 29, 2024 Category: Neurosurgery Authors: Ping Hu Yanze Wu Tengfeng Yan Lei Shu Feng Liu Bing Xiao Minhua Ye Miaojing Wu Shigang Lv Xingen Zhu Source Type: research