Efficacy and safety of a combination treatment of immune checkpoint inhibitors in metastatic breast cancer: a systematic review and meta-analysis
CONCLUSION: Pooled therapy had improved PFS in mTNBC patients, especially in patients with PD-L1-positive tumors, and it was less likely to cause grade ≥ 3 AEs.PMID:38587602 | DOI:10.1007/s12094-024-03396-6 (Source: Clinical Breast Cancer)
Source: Clinical Breast Cancer - April 8, 2024 Category: Cancer & Oncology Authors: Ying Wang Yalan Sun Fang Lu Xianghong Zhao Zhenlin Nie Feng Zhu Bangshun He Source Type: research
Efficacy and safety of a combination treatment of immune checkpoint inhibitors in metastatic breast cancer: a systematic review and meta-analysis
CONCLUSION: Pooled therapy had improved PFS in mTNBC patients, especially in patients with PD-L1-positive tumors, and it was less likely to cause grade ≥ 3 AEs.PMID:38587602 | DOI:10.1007/s12094-024-03396-6 (Source: Clinical Genitourinary Cancer)
Source: Clinical Genitourinary Cancer - April 8, 2024 Category: Cancer & Oncology Authors: Ying Wang Yalan Sun Fang Lu Xianghong Zhao Zhenlin Nie Feng Zhu Bangshun He Source Type: research
Clinicopathological and molecular predictors of [ < sup > 18 < /sup > F]FDG-PET disease detection in HER2-positive early breast cancer: RESPONSE, a substudy of the randomized PHERGain trial
CONCLUSIONS: These results highlight the clinical, biological, and metabolic heterogeneity of HER2+ breast cancer, which may facilitate the selection of HER2+ EBC patients likely to benefit from [18F]FDG-PET imaging as a tool to guide therapy.TRIAL REGISTRATION: Clinicaltrials.gov; NCT03161353; registration date: May 15, 2017.PMID:38587643 | DOI:10.1007/s00259-024-06683-0 (Source: Molecular Medicine)
Source: Molecular Medicine - April 8, 2024 Category: Molecular Biology Authors: Antonio Llombart-Cussac Aleix Prat Jos é Manuel Pérez-García Jos é Mateos Tom ás Pascual Santiago Escriv à-de-Romani Agostina Stradella Manuel Ruiz-Borrego Bego ña Bermejo de Las Heras Marleen Keyaerts Patricia Galvan Fara Bras ó-Maristany Juan Jo Source Type: research
Efficacy and safety of a combination treatment of immune checkpoint inhibitors in metastatic breast cancer: a systematic review and meta-analysis
ConclusionPooled therapy had improved PFS in mTNBC patients, especially in patients with PD-L1-positive tumors, and it was less likely to cause grade ≥ 3 AEs. (Source: Clinical and Translational Oncology)
Source: Clinical and Translational Oncology - April 8, 2024 Category: Cancer & Oncology Source Type: research
Clinicopathological and molecular predictors of [18F]FDG-PET disease detection in HER2-positive early breast cancer: RESPONSE, a substudy of the randomized PHERGain trial
ConclusionsThese results highlight the clinical, biological, and metabolic heterogeneity of HER2+ breast cancer, which may facilitate the selection of HER2+ EBC patients likely to benefit from [18F]FDG-PET imaging as a tool to guide therapy.Trial registrationClinicaltrials.gov; NCT03161353; registration date: May 15, 2017. (Source: European Journal of Nuclear Medicine and Molecular Imaging)
Source: European Journal of Nuclear Medicine and Molecular Imaging - April 8, 2024 Category: Nuclear Medicine Source Type: research
The extent of androgen receptor and HER2 expression allows for targeted therapy in most cases of salivary duct carcinoma: analysis of clinical and histopathological data in a tertiary care center
ConclusionsThe results suggest a rising SDC incidence and show that the extent of the AR and HER2 expression allows for targeted therapy in most SDC cases. (Source: European Archives of Oto-Rhino-Laryngology)
Source: European Archives of Oto-Rhino-Laryngology - April 8, 2024 Category: ENT & OMF Source Type: research
Exploratory analysis of serum HER2 extracellular domain for HER2 positive gastric cancer treated with SOX plus trastuzumab
ConclusionsBaseline sHER2 ECD levels and its early decline may be useful biomarkers for SOX plus trastuzumab efficacy in HER2 positive gastric cancer. (Source: International Journal of Clinical Oncology)
Source: International Journal of Clinical Oncology - April 8, 2024 Category: Cancer & Oncology Source Type: research
Clinicopathological and molecular predictors of [18F]FDG-PET disease detection in HER2-positive early breast cancer: RESPONSE, a substudy of the randomized PHERGain trial
ConclusionsThese results highlight the clinical, biological, and metabolic heterogeneity of HER2+ breast cancer, which may facilitate the selection of HER2+ EBC patients likely to benefit from [18F]FDG-PET imaging as a tool to guide therapy.Trial registrationClinicaltrials.gov; NCT03161353; registration date: May 15, 2017. (Source: European Journal of Nuclear Medicine and Molecular Imaging)
Source: European Journal of Nuclear Medicine and Molecular Imaging - April 8, 2024 Category: Nuclear Medicine Source Type: research
Cancers, Vol. 16, Pages 1433: Translational Aspects in Metaplastic Breast Carcinoma
This article reviews and summarizes the current knowledge and translational aspects of MpBC. (Source: Cancers)
Source: Cancers - April 7, 2024 Category: Cancer & Oncology Authors: Elizve Nairoby Barrientos-Toro Qingqing Ding Maria Gabriela Raso Tags: Review Source Type: research
Genomic ancestry and cancer among Latin Americans
Clin Transl Oncol. 2024 Apr 6. doi: 10.1007/s12094-024-03415-6. Online ahead of print.ABSTRACTLatin American populations, characterized by intricate admixture patterns resulting from the intermingling of ancestries from European, Native American (NA) Asian, and African ancestries which result in a vast and complex genetic landscape, harboring unique combinations of novel variants. This genetic diversity not only poses challenges in traditional population genetics methods but also opens avenues for a deeper understanding of its implications in health. In cancer, the interplay between genetic ancestry, lifestyle factors, and...
Source: Clinical Prostate Cancer - April 6, 2024 Category: Cancer & Oncology Authors: Alejandro Ru íz-Patiño Leonardo Rojas Jairo Zuluaga Oscar Arrieta Luis Corrales Claudio Mart ín Sandra Franco Luis Raez Christian Rolfo Natalia S ánchez Andr és Felipe Cardona Source Type: research
Genomic ancestry and cancer among Latin Americans
Clin Transl Oncol. 2024 Apr 6. doi: 10.1007/s12094-024-03415-6. Online ahead of print.ABSTRACTLatin American populations, characterized by intricate admixture patterns resulting from the intermingling of ancestries from European, Native American (NA) Asian, and African ancestries which result in a vast and complex genetic landscape, harboring unique combinations of novel variants. This genetic diversity not only poses challenges in traditional population genetics methods but also opens avenues for a deeper understanding of its implications in health. In cancer, the interplay between genetic ancestry, lifestyle factors, and...
Source: Clinical Lung Cancer - April 6, 2024 Category: Cancer & Oncology Authors: Alejandro Ru íz-Patiño Leonardo Rojas Jairo Zuluaga Oscar Arrieta Luis Corrales Claudio Mart ín Sandra Franco Luis Raez Christian Rolfo Natalia S ánchez Andr és Felipe Cardona Source Type: research
Genomic ancestry and cancer among Latin Americans
Clin Transl Oncol. 2024 Apr 6. doi: 10.1007/s12094-024-03415-6. Online ahead of print.ABSTRACTLatin American populations, characterized by intricate admixture patterns resulting from the intermingling of ancestries from European, Native American (NA) Asian, and African ancestries which result in a vast and complex genetic landscape, harboring unique combinations of novel variants. This genetic diversity not only poses challenges in traditional population genetics methods but also opens avenues for a deeper understanding of its implications in health. In cancer, the interplay between genetic ancestry, lifestyle factors, and...
Source: Clinical Breast Cancer - April 6, 2024 Category: Cancer & Oncology Authors: Alejandro Ru íz-Patiño Leonardo Rojas Jairo Zuluaga Oscar Arrieta Luis Corrales Claudio Mart ín Sandra Franco Luis Raez Christian Rolfo Natalia S ánchez Andr és Felipe Cardona Source Type: research
Genomic ancestry and cancer among Latin Americans
Clin Transl Oncol. 2024 Apr 6. doi: 10.1007/s12094-024-03415-6. Online ahead of print.ABSTRACTLatin American populations, characterized by intricate admixture patterns resulting from the intermingling of ancestries from European, Native American (NA) Asian, and African ancestries which result in a vast and complex genetic landscape, harboring unique combinations of novel variants. This genetic diversity not only poses challenges in traditional population genetics methods but also opens avenues for a deeper understanding of its implications in health. In cancer, the interplay between genetic ancestry, lifestyle factors, and...
Source: Clinical Genitourinary Cancer - April 6, 2024 Category: Cancer & Oncology Authors: Alejandro Ru íz-Patiño Leonardo Rojas Jairo Zuluaga Oscar Arrieta Luis Corrales Claudio Mart ín Sandra Franco Luis Raez Christian Rolfo Natalia S ánchez Andr és Felipe Cardona Source Type: research
Genomic ancestry and cancer among Latin Americans
Clin Transl Oncol. 2024 Apr 6. doi: 10.1007/s12094-024-03415-6. Online ahead of print.ABSTRACTLatin American populations, characterized by intricate admixture patterns resulting from the intermingling of ancestries from European, Native American (NA) Asian, and African ancestries which result in a vast and complex genetic landscape, harboring unique combinations of novel variants. This genetic diversity not only poses challenges in traditional population genetics methods but also opens avenues for a deeper understanding of its implications in health. In cancer, the interplay between genetic ancestry, lifestyle factors, and...
Source: Clinical Colorectal Cancer - April 6, 2024 Category: Cancer & Oncology Authors: Alejandro Ru íz-Patiño Leonardo Rojas Jairo Zuluaga Oscar Arrieta Luis Corrales Claudio Mart ín Sandra Franco Luis Raez Christian Rolfo Natalia S ánchez Andr és Felipe Cardona Source Type: research
Genomic ancestry and cancer among Latin Americans
Clin Transl Oncol. 2024 Apr 6. doi: 10.1007/s12094-024-03415-6. Online ahead of print.ABSTRACTLatin American populations, characterized by intricate admixture patterns resulting from the intermingling of ancestries from European, Native American (NA) Asian, and African ancestries which result in a vast and complex genetic landscape, harboring unique combinations of novel variants. This genetic diversity not only poses challenges in traditional population genetics methods but also opens avenues for a deeper understanding of its implications in health. In cancer, the interplay between genetic ancestry, lifestyle factors, and...
Source: Clinical Breast Cancer - April 6, 2024 Category: Cancer & Oncology Authors: Alejandro Ru íz-Patiño Leonardo Rojas Jairo Zuluaga Oscar Arrieta Luis Corrales Claudio Mart ín Sandra Franco Luis Raez Christian Rolfo Natalia S ánchez Andr és Felipe Cardona Source Type: research
