Fight Aging! Newsletter, January 15th 2024
In conclusion, FMD cycles have high potential to be effective in increasing the toxicity of a range of therapies against ALL and other blood cancers and should be tested in randomized clinical trials, especially in combination with immunotherapy and low toxicity cancer therapies.
In summary, we present a new strategy for improving leukemia treatment by combining FMD with chemotherapy to promote the killing of ALL cells in part by an immune-dependent mechanism. Fasting/FMD has been shown to reduce chemotherapy-associated toxicity in pre-clinical and clinical studies and thus represents a safe and potentially effectiv...
Source: Fight Aging! - January 14, 2024 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Continued Assessment of the Fasting Mimicking Diet as an Adjuvant Cancer Therapy
In conclusion, FMD cycles have high potential to be effective in increasing the toxicity of a range of therapies against ALL and other blood cancers and should be tested in randomized clinical trials, especially in combination with immunotherapy and low toxicity cancer therapies.
In summary, we present a new strategy for improving leukemia treatment by combining FMD with chemotherapy to promote the killing of ALL cells in part by an immune-dependent mechanism. Fasting/FMD has been shown to reduce chemotherapy-associated toxicity in pre-clinical and clinical studies and thus represents a safe and potentially effectiv...
Source: Fight Aging! - January 12, 2024 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs
Bonus Features – September 10, 2023 – 77% of clinicians see RPM outpacing traditional inpatient care within five years, Microsoft partnering with Paige on pathology and oncology AI models, and more
This article will be a weekly roundup of interesting stories, product announcements, new hires, partnerships, research studies, awards, sales, and more. Because there’s so much happening out there in healthcare IT we aren’t able to cover in our full articles, we still want to make sure you’re informed of all the latest news, announcements, and stories happening to help you better do your job.
News
Executives for Healthcare Innovation is transferring its assets to the American Telemedicine Association, and ATA will extend engagement opportunities to current EHI members through its various Special Interest Groups.
More...
Source: EMR and HIPAA - September 11, 2023 Category: Information Technology Authors: Brian Eastwood Tags: Healthcare IT Adrian Agostini Alo American Telemedicine Association Andrea Rowe Anki ATA AVIA Black Book Research Canopy Edifecs Experity Healthcare IT Today Bonus Features HITRUST Ibex Medical Analytics iMerit Inovalon K Source Type: blogs
Making Tumors Tastier for the Immune System
Researchers at The University of Texas MD Anderson Cancer Center have developed a nanotechnology platform that can make cancer cells more vulnerable to immune attack in the body. The researchers call their system the bispecific tumor-transforming nanoconjugate (BiTN) platform.
The idea is to make solid tumors more appealing for the immune system by attaching a molecule that acts as an “eat me” signal to white blood cells. This molecule is called signaling lymphocytic activation molecule family member 7 (SLAMF7) receptor and is more commonly found on cancer cells in blood cancers, which explains the relative success...
Source: Medgadget - November 15, 2022 Category: Medical Devices Authors: Conn Hastings Tags: Medicine Nanomedicine Oncology MDAndersonNews Source Type: blogs
Can some postmenopausal women with breast cancer skip chemotherapy?
Breast cancer remains the most common cancer among women. In the last two decades, the treatment of breast cancers has become personalized. This has been possible due to the subtyping of breast cancers. Breast cancers have been subtyped based on the receptors on the breast cancer cell. The most clinically significant receptors — those that have targeted therapies — are the estrogen and progesterone receptors and the human epidermal growth factor receptor 2 (HER2). Cancers that have the estrogen and progesterone receptors are termed hormone receptor (HR)-positive cancers.
The development of hormone therapy for HR-positi...
Source: Harvard Health Blog - April 15, 2021 Category: Consumer Health News Authors: Salewa T. Salewa Oseni, MD Tags: Cancer Medical Research Women's Health Source Type: blogs
Evaluation of the Surgical Specimen After Neoadjuvant Systemic Therapy
ConclusionPostneoadjuvant systemic therapy histopathological changes are complex, and careful systematic review of the specimen is required for accurate diagnosis and follow-up treatment. For pathological complete response to be used as an indicator of response to novel therapies, it is essential to have a standardized way in which residual disease is measured and reported. We designed the recommendations specifically for the clinical trial setting; however, they can be optionally incorporated into routine practice because, in our opinion, standardization is most effective when uniformly applied. Hopefully, such standardiz...
Source: Oncopathology - March 23, 2021 Category: Cancer & Oncology Tags: breast Breast Biopsy Procedure breast cancer Source Type: blogs
Stomach Cancer Stage 4 Treatment
Stomach cancer stage 4 is a complex diagnosis. It is the stage of cancer that requires specific treatment options.
Is surgery an option for patients with stomach cancer stage 4?
Stage 4 stomach cancer is characterized by rapid tumor growth, metastasizing to regional lymph nodes and distant organs (liver, bones, pancreas, less often lungs). With the development of metastases in other organs, characteristic symptoms occur such as jaundice and liver failure with liver damage, ascites with metastases in the peritoneum, bowel obstruction with metastases in the small intestine, etc.
Therefore, at the advanced stages, ga...
Source: PickTheBrain | Motivation and Self Improvement - January 22, 2021 Category: Consumer Health News Authors: Booking Health Tags: health and fitness self-improvement cancer stomach cancer treatment Source Type: blogs
Aspirin and breast cancer risk: How a wonder drug may become more wonderful
Aspirin has been called a wonder drug. And it’s easy to see why.
It’s inexpensive, its side effects are well-known and generally minor. And since it was developed in the 1890s, it’s been shown to provide a number of potential benefits, such as relieving pain, bringing down a fever, and preventing heart attacks and strokes. Over the last 20 years or so, the list of aspirin’s potential benefits has been growing. And it might be about to get even longer: did you know that aspirin may lower your risk of several types of cancer?
Studies of aspirin and cancer
A number of studies suggest that aspirin can lower the risk of...
Source: Harvard Health Blog - October 23, 2020 Category: Consumer Health News Authors: Robert H. Shmerling, MD Tags: Breast Cancer Health Source Type: blogs
Fight Aging! Newsletter, September 28th 2020
In conclusion, it remains unclear if brain-specific regional and temporal changes occur in the expression of the different APP variants during AD progression. Since APP is also found in blood cells, assessing the changes in APP mRNA expression in peripheral blood cells from AD patients has been considering an alternative. However, again the quantification of APP mRNA in peripheral blood cells has generated controversial results.
Brain APP protein has been analyzed in only a few studies, probably as it is difficult to interpret the complex pattern of APP variants and fragments. We previously characterized the soluabl...
Source: Fight Aging! - September 27, 2020 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Fasting Mimicking Diet Improves Chemotherapy Effectiveness and Reduces Side Effects
The fasting mimicking diet emerged from efforts to better define the dose-response curve for beneficial effects resulting from a reduced calorie intake. Fasting is beneficial, calorie restriction is beneficial, but where are the dividing lines? How much food can one eat and still obtain near all of the benefits of fasting? As a result of this work, the fasting mimicking diet has undergone clinical testing in cancer patients. Numerous benefits have been demonstrated, and the paper here is an example of the type. In this human trial, fasting mimicking reduced the negative short term impact of chemotherapy on health, and, fur...
Source: Fight Aging! - September 22, 2020 Category: Research Authors: Reason Tags: Daily News Source Type: blogs
Magnetized Particles Show Live Metabolic Activity of Breast Cancer
Current imaging methods that are used to spot tumors don’t provide much information about the rate of activity of the cells making up the diseased tissues. Breast cancer tumors, for example, are mostly classified into a few categories based on hormone receptor and HER2 expression.
Researchers at Cancer Research UK Cambridge Institute and the Department of Radiology at the University of Cambridge are now reporting in Proceedings of the National Academy of Sciences that they’ve used magnetized particles to image the actual metabolic activity of breast cancer tumors. This may provide a relatively accessible ne...
Source: Medgadget - January 24, 2020 Category: Medical Devices Authors: Medgadget Editors Tags: Diagnostics Materials Medicine Oncology Radiology Source Type: blogs
New Nanoparticles to Stop Growth of HER2-Positive Breast Cancer
HER2 (human epidermal growth factor receptor 2) is a protein that is associated with some particularly aggressive forms of breast cancer. The presence of high concentrations of this protein seems to lead to the growth of tumors, so inactivating HER2 may help to stop the spread of certain strains of cancer in the body.
An existing technique involves introducing an antibody that can block HER2 from binding to other things, but now researchers at Nanjing University in China have developed a polymer nanoparticle that can bind to HER2 just as well as antibodies. These nanoparticles can halt the normal functionality of H...
Source: Medgadget - July 17, 2019 Category: Medical Devices Authors: Medgadget Editors Tags: Ob/Gyn Oncology Source Type: blogs
Synthetic Proteins Designed to Halt Growth of Cancers
Stanford University scientists have developed a novel approach to halting the growth of cancer cells while preserving normal function in healthy cells. The research was published in journal Science, and though it was so far conducted only on groups of cancer cells outside a body, the findings are incredibly promising.
The new approach focuses on manipulating signaling pathways within cellular membranes that are involved in the growth of cells. Receptor proteins within membranes of cancer cells are often mutated or expressed in higher than normal concentrations, resulting in them effectively being “always on”. T...
Source: Medgadget - May 17, 2019 Category: Medical Devices Authors: Editors Tags: Genetics Materials Oncology Source Type: blogs
Last Couple of Months in Oncology with Dr. Bishal Gyawali: March 2019
By BISHAL GYAWALI MD, PhD
Hey, I’m back!
Well, you might not have noticed that my blogs were missing for the last three months but anyways, its good to be back. I was having a little time off blogs and social media as I was transitioning in my career but now I am back. Sometimes, it is very difficult to manage time for things that you must do versus things you enjoy doing, especially when these two don’t intersect. For me, these last few months the things I had to do were all bureaucratic while I couldn’t find the time for things I enjoy doing like writing these blogs. But now that we are back, let’s rec...
Source: The Health Care Blog - March 26, 2019 Category: Consumer Health News Authors: Matthew Holt Tags: Medical Practice Physicians Bishal Gyawali Cancer drugs Clinical Trials Oncology Prostate Cancer RCTs Source Type: blogs
