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Effects of Lactobacillus paracasei N1115 on gut microbial imbalance and liver function in patients with hepatitis B-related cirrhosis
CONCLUSION: LP N1115 is a promising treatment for ameliorating intestinal microbial imbalance in HBC patients by modulating the structure of the intestinal microbiota, improving liver function, and reducing inflammatory factor levels.PMID:38617455 | PMC:PMC11008409 | DOI:10.3748/wjg.v30.i11.1556 (Source: World Journal of Gastroenterology : WJG)
Source: World Journal of Gastroenterology : WJG - April 15, 2024 Category: Gastroenterology Authors: Yan-Chao Hu Xiang-Chun Ding Hui-Juan Liu Wan-Long Ma Xue-Yan Feng Li-Na Ma Source Type: research

Assessing recent recurrence after hepatectomy for hepatitis B-related hepatocellular carcinoma by a predictive model based on sarcopenia
CONCLUSION: Sarcopenia is associated with recent recurrence after hepatectomy for hepatitis B-related HCC. A nutritional status-based prediction model is first established for postoperative recurrence of hepatitis B-related HCC, which is superior to other models and contributes to prognosis prediction.PMID:38617742 | PMC:PMC11008376 | DOI:10.3748/wjg.v30.i12.1727 (Source: World Journal of Gastroenterology)
Source: World Journal of Gastroenterology - April 15, 2024 Category: Gastroenterology Authors: Hong Peng Si-Yi Lei Wei Fan Yu Dai Yi Zhang Gen Chen Ting-Ting Xiong Tian-Zhao Liu Yue Huang Xiao-Feng Wang Jin-Hui Xu Xin-Hua Luo Source Type: research

Effects of Lactobacillus paracasei N1115 on gut microbial imbalance and liver function in patients with hepatitis B-related cirrhosis
CONCLUSION: LP N1115 is a promising treatment for ameliorating intestinal microbial imbalance in HBC patients by modulating the structure of the intestinal microbiota, improving liver function, and reducing inflammatory factor levels.PMID:38617455 | PMC:PMC11008409 | DOI:10.3748/wjg.v30.i11.1556 (Source: World Journal of Gastroenterology)
Source: World Journal of Gastroenterology - April 15, 2024 Category: Gastroenterology Authors: Yan-Chao Hu Xiang-Chun Ding Hui-Juan Liu Wan-Long Ma Xue-Yan Feng Li-Na Ma Source Type: research

Assessing recent recurrence after hepatectomy for hepatitis B-related hepatocellular carcinoma by a predictive model based on sarcopenia
CONCLUSION: Sarcopenia is associated with recent recurrence after hepatectomy for hepatitis B-related HCC. A nutritional status-based prediction model is first established for postoperative recurrence of hepatitis B-related HCC, which is superior to other models and contributes to prognosis prediction.PMID:38617742 | PMC:PMC11008376 | DOI:10.3748/wjg.v30.i12.1727 (Source: World Journal of Gastroenterology : WJG)
Source: World Journal of Gastroenterology : WJG - April 15, 2024 Category: Gastroenterology Authors: Hong Peng Si-Yi Lei Wei Fan Yu Dai Yi Zhang Gen Chen Ting-Ting Xiong Tian-Zhao Liu Yue Huang Xiao-Feng Wang Jin-Hui Xu Xin-Hua Luo Source Type: research

Effects of Lactobacillus paracasei N1115 on gut microbial imbalance and liver function in patients with hepatitis B-related cirrhosis
CONCLUSION: LP N1115 is a promising treatment for ameliorating intestinal microbial imbalance in HBC patients by modulating the structure of the intestinal microbiota, improving liver function, and reducing inflammatory factor levels.PMID:38617455 | PMC:PMC11008409 | DOI:10.3748/wjg.v30.i11.1556 (Source: World Journal of Gastroenterology)
Source: World Journal of Gastroenterology - April 15, 2024 Category: Gastroenterology Authors: Yan-Chao Hu Xiang-Chun Ding Hui-Juan Liu Wan-Long Ma Xue-Yan Feng Li-Na Ma Source Type: research

Viruses, Vol. 16, Pages 609: Mechanisms of Hepatitis B Virus cccDNA and Minichromosome Formation and HBV Gene Transcription
ss Hepatitis B virus (HBV) is the etiologic agent of chronic hepatitis B, which puts at least 300 million patients at risk of developing fibrosis, cirrhosis, and hepatocellular carcinoma. HBV is a partially double-stranded DNA virus of the Hepadnaviridae family. While HBV was discovered more than 50 years ago, many aspects of its replicative cycle remain incompletely understood. Central to HBV persistence is the formation of covalently closed circular DNA (cccDNA) from the incoming relaxed circular DNA (rcDNA) genome. cccDNA persists as a chromatinized minichromosome and is the major template for HBV gene transcription...
Source: Viruses - April 15, 2024 Category: Virology Authors: Andoni G ómez-Moreno Alexander Ploss Tags: Review Source Type: research

Cancers, Vol. 16, Pages 1505: The Role of Hepatitis Viruses as Drivers of Hepatocancerogenesis
a Morisco Recently, metabolic associated steatotic liver disease (MASLD) became the leading cause of chronic liver disease worldwide and one of the most frequent causes of hepatocellular carcinoma (HCC). Nonetheless, in this epidemiological trend, viral hepatitis remains the major driver in hepatic carcinogenesis. Globally, hepatitis B virus (HBV) is the leading cause of hepatocellular carcinoma, with an overall attributable risk of approximately 40%, followed by hepatitis C virus (HCV), which accounts for 28&ndash;30% of cases, with significant geographic variations between the Eastern and Western world. Consi...
Source: Cancers - April 15, 2024 Category: Cancer & Oncology Authors: Mario Capasso Valentina Cossiga Maria Guarino Luisa Ranieri Filomena Morisco Tags: Review Source Type: research

Elevation of S2-bound α1-acid glycoprotein is associated with chronic hepatitis C virus infection and hepatocellular carcinoma
J Viral Hepat. 2024 Apr 12. doi: 10.1111/jvh.13943. Online ahead of print.ABSTRACTThere is an urgent need for new high-quality markers for the early detection of hepatocellular carcinoma (HCC). Åström et al. suggested that S2-bound α1-acid glycoprotein (AGP) might be a promising marker. Consequently, we evaluated the predictive advantage of S2-bound AGP in the early detection of HCC. In a retrospective case-control study of patients chronically infected with hepatitis C virus (HCV) and treated with direct-acting antiviral agents (n = 93), we measured S2-bound AGP using the HepaCheC® ELISA kit (Glycobond AB, Linköping,...
Source: Cancer Control - April 13, 2024 Category: Cancer & Oncology Authors: Carlos Oltmanns Birgit Bremer Laura Kusche Per St ål Robin Zenlander Jan Tauwaldt Ingvar Ryd én Peter P åhlsson Markus Cornberg Heiner Wedemeyer Source Type: research

Transfusion-transmitted infections
Blood Res. 2024 Apr 12;59(1):14. doi: 10.1007/s44313-024-00014-w.ABSTRACTThe risk of transfusion-transmitted infection (TTI) has always existed because transfused blood products are biological materials derived from humans. To prevent TTIs, screening strategies have been developed for various infectious diseases, such as hepatitis B virus, hepatitis C virus, and human immunodeficiency virus, contributing significantly to reducing TTI globally. Nevertheless, septic transfusion reactions (STRs) due to bacterial contamination remain an unresolved issue. Various infectious diseases can be transmitted through blood products, an...
Source: Blood Research - April 12, 2024 Category: Hematology Authors: Han Joo Kim Dae-Hyun Ko Source Type: research

Successful therapy with tenofovir disoproxil fumarate (TDF) in patients with chronic hepatitis B (CHB) does not guarantee amelioration of liver damage assessing by transient elastography. A retrospective - prospective multicenter study
Preventing disease progression and viral suppression are the main goals of antiviral therapy in chronic hepatitis B (CHB). Liver stiffness measurement (LSM) by transient elastography is a reliable non-invasive... (Source: BMC Gastroenterology)
Source: BMC Gastroenterology - April 12, 2024 Category: Gastroenterology Authors: Hariklia Kranidioti, Konstantinos Zisimopoulos, Theodora Oikonomou, Theodoros Voulgaris, Spyros Siakavellas, Polixeni Agorastou, Melanie Deutsch, Christos Triantos, Ioannis Goulis, George Papatheodoridis and Spilios Manolakopoulos Tags: Research Source Type: research

Seroprevalence of Hepatitis B and C Viruses and Their Associated Factors Among Military Personnel at Military Camps in Central Gondar, Ethiopia: A Cross-Sectional Study
(Source: Infection and Drug Resistance)
Source: Infection and Drug Resistance - April 11, 2024 Category: Infectious Diseases Tags: Infection and Drug Resistance Source Type: research

Viruses, Vol. 16, Pages 592: High Prevalence of Hepatitis B Virus Drug Resistance Mutations to Lamivudine among People with HIV/HBV Coinfection in Rural and Peri-Urban Communities in Botswana
Conclusions: The high prevalence of lamivudine RAMs discourages the use of ART regimens with 3TC as the only HBV-active drug in people with HIV/HBV. (Source: Viruses)
Source: Viruses - April 11, 2024 Category: Virology Authors: Bonolo B. Phinius Motswedi Anderson Irene Gobe Margaret Mokomane Wonderful T. Choga Basetsana Phakedi Tsholofelo Ratsoma Gorata Mpebe Joseph Makhema Roger Shapiro Shahin Lockman Rosemary Musonda Sikhulile Moyo Simani Gaseitsiwe Tags: Article Source Type: research