TFE3 rearranged epithelioid hemangioendothelioma of the lymph node: A rare primary presentation of vascular tumor
We present a 49-year-old male patient who presented with an inguinal mass but was otherwise asymptomatic. Clinical and radiological workup failed to reveal any other primary lesion. The lymph node was excised and the histomorphological examination showed an epithelioid and spindle neoplasm with chondromyxoid stroma. The diagnosis of epithelioid hemangioendothelioma was suspected based on histomorphology and immunohistochemistry, which showed diffuse positivity for CD31, CD34, and TFE3 stains. This was further confirmed by the fluorescent in-situ hybridization (FISH) technique that showed TFE3 gene rearrangement.PMID:385637...
Source: Indian Journal of Pathology and Microbiology - April 2, 2024 Category: Pathology Authors: Ann Thomas Swapnil U Rane Santosh Menon Source Type: research

A case of primary pleural epithelioid hemangioendothelioma achieving stable disease with paclitaxel treatment: A case report and literature review
Pleural epithelioid hemangioendothelioma (EHE) is exceptionally rare, and the prognosis for pleural EHE is grim, typically resulting in a survival of less than 1 year. In this case report, we present the case of a 45-year-old woman who endured 1 month of right-sided pleuritic chest pain, was diagnosed with right pleural EHE, and achieved an 11-month progression-free survival following paclitaxel treatment. AbstractEpithelioid hemangioendothelioma (EHE) is a rare vascular neoplasm with a clinical behaviour that falls between a benign hemangioma and a high-grade angiosarcoma. Pleural EHE is exceptionally rare, and its progno...
Source: Respirology Case Reports - March 29, 2024 Category: Respiratory Medicine Authors: Chun ‐Ying Chou, Hsiang‐Wei Hu, Tom Wei‐Wu Chen, Shu‐Yung Lin Tags: CASE REPORT Source Type: research

Image-guided Thermal Ablation for Hepatic Epithelioid Hemangioendothelioma: A Multicenter Experience
The feasibility, safety and clinical outcomes of image-guided thermal ablation in patients with hepatic epithelioid hemangioendothelioma (HEHE) were investigated. (Source: Journal of Vascular and Interventional Radiology : JVIR)
Source: Journal of Vascular and Interventional Radiology : JVIR - March 25, 2024 Category: Radiology Authors: Qianqian Zeng, Yanchun Luo, Jie Yu, Xin Li, Tian-an Jiang, Xiaoyan Xie, Gang Dong, Ping Liang Tags: Clinical Study Source Type: research

Pseudomyogenic Hemangioendothelioma Arising in the Maxillary Sinus, an Uncommon and Misdiagnosed Tumor: A Case Report
Ear Nose Throat J. 2024 Mar 20:1455613241239859. doi: 10.1177/01455613241239859. Online ahead of print.ABSTRACTPseudomyogenic hemangioendothelioma (PMHE) is a rare vascular neoplasm with an intermediate to low-grade malignant potential. Only 5% of PMHEs occur in the head and neck. This tumor exhibits different histological patterns and mimics other vascular tumors, myoid tumors, or carcinomas. The distinction between these tumors can be a very challenging situation for pathologists. In this article, we report the first case, to our knowledge, of PMHE arising in the maxillary sinus, to highlight this uncommon entity and dis...
Source: Ear, Nose and Throat Journal - March 21, 2024 Category: ENT & OMF Authors: Hafsa El Ouazzani Olaya Hamidi Alain Habimana M Boulaadas Fouad Zouaidia Nadia Cherradi Source Type: research

Construction and applications of the EOMA spheroid model of Kaposiform hemangioendothelioma
Kaposiform hemangioendothelioma (KHE) is a rare intermediate vascular tumor with unclear pathogenesis. Recently, three dimensional (3D) cell spheroids and organoids have played an indispensable role in the stu... (Source: Journal of Biological Engineering)
Source: Journal of Biological Engineering - March 14, 2024 Category: Biotechnology Authors: Yanan Li, Xinglong Zhu, Li Li, Chunjuan Bao, Qin Liu, Ning zhang, Ziyan He, Yi Ji and Ji Bao Tags: Research Source Type: research

Dural composite hemangioendothelioma: The first intracranial case
CONCLUSION: The spectrum of mesenchymal neoplasms within the cranium expands to encompass CHE.PMID:38468685 | PMC:PMC10927221 | DOI:10.25259/SNI_3_2024 (Source: Surgical Neurology International)
Source: Surgical Neurology International - March 12, 2024 Category: Neurosurgery Authors: Alice Liu Joshua S Bauer Chun-Chieh Lin Geoff Appelboom George Zanazzi Source Type: research