Prevalence and clinical features of orbital vascular anomalies in children
CONCLUSIONS: Capillary hemangiomas and low-flow lymphatic malformations comprise most of the orbital vascular anomalies in this cohort of children. Amblyopia and strabismus are common sequelae, highlighting the importance of early diagnosis and appropriate management.PMID:36644978 | DOI:10.1080/01676830.2023.2166081 (Source: Orbit)
Source: Orbit - January 16, 2023 Category: Opthalmology Authors: Laura A Torrado-Cobian Gregory J Griepentrog David O Hodge Brian G Mohney Source Type: research

Prevalence and clinical features of orbital vascular anomalies in children
CONCLUSIONS: Capillary hemangiomas and low-flow lymphatic malformations comprise most of the orbital vascular anomalies in this cohort of children. Amblyopia and strabismus are common sequelae, highlighting the importance of early diagnosis and appropriate management.PMID:36644978 | DOI:10.1080/01676830.2023.2166081 (Source: Orbit)
Source: Orbit - January 16, 2023 Category: Opthalmology Authors: Laura A Torrado-Cobian Gregory J Griepentrog David O Hodge Brian G Mohney Source Type: research

Prevalence and clinical features of orbital vascular anomalies in children
CONCLUSIONS: Capillary hemangiomas and low-flow lymphatic malformations comprise most of the orbital vascular anomalies in this cohort of children. Amblyopia and strabismus are common sequelae, highlighting the importance of early diagnosis and appropriate management.PMID:36644978 | DOI:10.1080/01676830.2023.2166081 (Source: Orbit)
Source: Orbit - January 16, 2023 Category: Opthalmology Authors: Laura A Torrado-Cobian Gregory J Griepentrog David O Hodge Brian G Mohney Source Type: research

Prevalence and clinical features of orbital vascular anomalies in children
CONCLUSIONS: Capillary hemangiomas and low-flow lymphatic malformations comprise most of the orbital vascular anomalies in this cohort of children. Amblyopia and strabismus are common sequelae, highlighting the importance of early diagnosis and appropriate management.PMID:36644978 | DOI:10.1080/01676830.2023.2166081 (Source: Orbit)
Source: Orbit - January 16, 2023 Category: Opthalmology Authors: Laura A Torrado-Cobian Gregory J Griepentrog David O Hodge Brian G Mohney Source Type: research

CT and MRI features of hepatic epithelioid haemangioendothelioma: a multi-institutional retrospective analysis of 15 cases and a literature review
ConclusionsHEHEs have common distinctive features, including multifocal lesions that are predominantly peripheral, “target signs”, “lollipop signs”, hepatic capsular retraction and peripheral enhancement of various shapes in the early phase with progressive centripetal filling. Additional aggressive imaging features that may be valuable clues to the diagnosis can be identified by CT or MRI. (Source: Insights into Imaging)
Source: Insights into Imaging - January 5, 2023 Category: Radiology Source Type: research

Loss of CDKN2A cooperates with WWTR1(TAZ)-CAMTA1 gene fusion to promote tumor progression in epithelioid hemangioendothelioma
CONCLUSION: CDKN2A loss enhances the tumorigenicity of EHE in vivo and enabled the generation of. the first cell lines of this disease. These cell line replicate key facets of the human disease phenotype. Therefore, these cell lines and allograft tumors generated after implantation serve as robust model systems for therapeutic testing of compounds either directed at EHE or at other TAZ-driven cancers.PMID:36598859 | DOI:10.1158/1078-0432.CCR-22-2497 (Source: Cell Research)
Source: Cell Research - January 4, 2023 Category: Cytology Authors: Caleb N Seavey Andrea Hallett Shuo Li Kepeng Che Ajaybabu V Pobbati Shuang Ma Ashley Burtscher Ryan Kanai John M Lamar Brian P Rubin Source Type: research

Loss of CDKN2A cooperates with WWTR1(TAZ)-CAMTA1 gene fusion to promote tumor progression in epithelioid hemangioendothelioma
CONCLUSION: CDKN2A loss enhances the tumorigenicity of EHE in vivo and enabled the generation of. the first cell lines of this disease. These cell line replicate key facets of the human disease phenotype. Therefore, these cell lines and allograft tumors generated after implantation serve as robust model systems for therapeutic testing of compounds either directed at EHE or at other TAZ-driven cancers.PMID:36598859 | DOI:10.1158/1078-0432.CCR-22-2497 (Source: Clinical Cancer Research)
Source: Clinical Cancer Research - January 4, 2023 Category: Cancer & Oncology Authors: Caleb N Seavey Andrea Hallett Shuo Li Kepeng Che Ajaybabu V Pobbati Shuang Ma Ashley Burtscher Ryan Kanai John M Lamar Brian P Rubin Source Type: research

Loss of CDKN2A cooperates with WWTR1(TAZ)-CAMTA1 gene fusion to promote tumor progression in epithelioid hemangioendothelioma
CONCLUSION: CDKN2A loss enhances the tumorigenicity of EHE in vivo and enabled the generation of. the first cell lines of this disease. These cell line replicate key facets of the human disease phenotype. Therefore, these cell lines and allograft tumors generated after implantation serve as robust model systems for therapeutic testing of compounds either directed at EHE or at other TAZ-driven cancers.PMID:36598859 | DOI:10.1158/1078-0432.CCR-22-2497 (Source: Cell Research)
Source: Cell Research - January 4, 2023 Category: Cytology Authors: Caleb N Seavey Andrea Hallett Shuo Li Kepeng Che Ajaybabu V Pobbati Shuang Ma Ashley Burtscher Ryan Kanai John M Lamar Brian P Rubin Source Type: research

Loss of CDKN2A cooperates with WWTR1(TAZ)-CAMTA1 gene fusion to promote tumor progression in epithelioid hemangioendothelioma
CONCLUSION: CDKN2A loss enhances the tumorigenicity of EHE in vivo and enabled the generation of. the first cell lines of this disease. These cell line replicate key facets of the human disease phenotype. Therefore, these cell lines and allograft tumors generated after implantation serve as robust model systems for therapeutic testing of compounds either directed at EHE or at other TAZ-driven cancers.PMID:36598859 | DOI:10.1158/1078-0432.CCR-22-2497 (Source: Clinical Cancer Research)
Source: Clinical Cancer Research - January 4, 2023 Category: Cancer & Oncology Authors: Caleb N Seavey Andrea Hallett Shuo Li Kepeng Che Ajaybabu V Pobbati Shuang Ma Ashley Burtscher Ryan Kanai John M Lamar Brian P Rubin Source Type: research

A Case Report of Rare Vocal Cord Hemangioendothelioma in a Paediatric Larynx
We present a rare case of HEM arising from the vocal cord of a 10-year-old female child. Video laryngoscopy clearly showed a large vocal cord polyp-like mass attached to middle one-third of left cord. Histopathological examination showed fragments of tissue with a neoplasm composed of spindle cells arranged diffusely admixed with numerous small vascular channels. These specific cells were positive for CD31, CD34, vimentin and ERG. Flexiblescopy and narrow band imaging were performed 3  weeks after surgery which showed no residual mass. Treatment of HEM is hampered by lack of proper guidelines and protocol. In this case of...
Source: Indian Journal of Otolaryngology and Head and Neck Surgery - December 29, 2022 Category: ENT & OMF Source Type: research

Ultrasound and contrast-enhanced ultrasound imaging in hepatic epithelioid hemangioendothelioma: a retrospective study of 13 patients
Med Ultrason. 2022 Dec 21;24(4):414-420. doi: 10.11152/mu-3683.NO ABSTRACTPMID:36546435 | DOI:10.11152/mu-3683 (Source: Medical Ultrasonography)
Source: Medical Ultrasonography - December 22, 2022 Category: Radiology Authors: Ling Ren Xiang Fei Yaqiong Zhu Yukun Luo Source Type: research

Ultrasound and contrast-enhanced ultrasound imaging in hepatic epithelioid hemangioendothelioma: a retrospective study of 13 patients
CONCLUSIONS: The grayscale US and CEUS seem to provide some reference value for diagnosing HEHE.PMID:36546435 | DOI:10.11152/mu-3683 (Source: Medical Ultrasonography)
Source: Medical Ultrasonography - December 22, 2022 Category: Radiology Authors: Ling Ren Xiang Fei Yaqiong Zhu Yukun Luo Source Type: research