Highly Pathogenic Avian Influenza A(H5N1) Viruses from Multispecies Outbreak, Argentina, August 2023
A. Rimondi et al. (Source: Emerging Infectious Diseases Journal)
Source: Emerging Infectious Diseases Journal - February 27, 2024 Category: Infectious Diseases Source Type: research

Recent Changes in Patterns of Mammal Infection with Highly Pathogenic Avian Influenza A(H5N1) Virus Worldwide
Emerg Infect Dis. 2024 Mar;30(3):444-452. doi: 10.3201/eid3003.231098.ABSTRACTWe reviewed information about mammals naturally infected by highly pathogenic avian influenza A virus subtype H5N1 during 2 periods: the current panzootic (2020-2023) and previous waves of infection (2003-2019). In the current panzootic, 26 countries have reported >48 mammal species infected by H5N1 virus; in some cases, the virus has affected thousands of individual animals. The geographic area and the number of species affected by the current event are considerably larger than in previous waves of infection. The most plausible source of mamm...
Source: Emerging Infectious Diseases - February 26, 2024 Category: Infectious Diseases Authors: Pablo I Plaza V íctor Gamarra-Toledo Juan Rodr íguez Euguí Sergio A Lambertucci Source Type: research

Highly Pathogenic Avian Influenza A(H5N1) Virus Clade 2.3.4.4b in Domestic Ducks, Indonesia, 2022
Emerg Infect Dis. 2024 Mar;30(3):586-590. doi: 10.3201/eid3003.230973.ABSTRACTHighly pathogenic avian influenza A(H5N1) clade 2.3.4.4b viruses were isolated from domestic ducks in South Kalimantan, Indonesia, during April 2022. The viruses were genetically similar to those detected in East Asia during 2021-2022. Molecular surveillance of wild birds is needed to detect potential pandemic threats from avian influenza virus.PMID:38407163 | DOI:10.3201/eid3003.230973 (Source: Emerging Infectious Diseases)
Source: Emerging Infectious Diseases - February 26, 2024 Category: Infectious Diseases Authors: Hendra Wibawa Putut Eko Wibowo Arif Supriyadi Lestari Lestari Jessiaman Silaban Aziz Ahmad Fuadi Anna Januar Fiqri Retno Wulan Handayani Sri Handayani Irianingsih Zaza Fahmia Herdiyanto Mulyawan Syafrison Idris Nuryani Zainuddin Source Type: research

Recent Changes in Patterns of Mammal Infection with Highly Pathogenic Avian Influenza A(H5N1) Virus Worldwide
Emerg Infect Dis. 2024 Mar;30(3):444-452. doi: 10.3201/eid3003.231098.ABSTRACTWe reviewed information about mammals naturally infected by highly pathogenic avian influenza A virus subtype H5N1 during 2 periods: the current panzootic (2020-2023) and previous waves of infection (2003-2019). In the current panzootic, 26 countries have reported >48 mammal species infected by H5N1 virus; in some cases, the virus has affected thousands of individual animals. The geographic area and the number of species affected by the current event are considerably larger than in previous waves of infection. The most plausible source of mamm...
Source: Emerging Infectious Diseases - February 26, 2024 Category: Infectious Diseases Authors: Pablo I Plaza V íctor Gamarra-Toledo Juan Rodr íguez Euguí Sergio A Lambertucci Source Type: research

Highly Pathogenic Avian Influenza A(H5N1) Virus Clade 2.3.4.4b in Domestic Ducks, Indonesia, 2022
Emerg Infect Dis. 2024 Mar;30(3):586-590. doi: 10.3201/eid3003.230973.ABSTRACTHighly pathogenic avian influenza A(H5N1) clade 2.3.4.4b viruses were isolated from domestic ducks in South Kalimantan, Indonesia, during April 2022. The viruses were genetically similar to those detected in East Asia during 2021-2022. Molecular surveillance of wild birds is needed to detect potential pandemic threats from avian influenza virus.PMID:38407163 | DOI:10.3201/eid3003.230973 (Source: Emerging Infectious Diseases)
Source: Emerging Infectious Diseases - February 26, 2024 Category: Infectious Diseases Authors: Hendra Wibawa Putut Eko Wibowo Arif Supriyadi Lestari Lestari Jessiaman Silaban Aziz Ahmad Fuadi Anna Januar Fiqri Retno Wulan Handayani Sri Handayani Irianingsih Zaza Fahmia Herdiyanto Mulyawan Syafrison Idris Nuryani Zainuddin Source Type: research

Viruses, Vol. 16, Pages 358: Genetics of H5N1 and H5N8 High-Pathogenicity Avian Influenza Viruses Isolated in Japan in Winter 2021 & ndash;2022
Viruses, Vol. 16, Pages 358: Genetics of H5N1 and H5N8 High-Pathogenicity Avian Influenza Viruses Isolated in Japan in Winter 2021–2022 Viruses doi: 10.3390/v16030358 Authors: Junki Mine Yoshihiro Takadate Asuka Kumagai Saki Sakuma Ryota Tsunekuni Kohtaro Miyazawa Yuko Uchida In winter 2021–2022, H5N1 and H5N8 high-pathogenicity avian influenza (HPAI) viruses (HPAIVs) caused serious outbreaks in Japan: 25 outbreaks of HPAI at poultry farms and 107 cases in wild birds or in the environment. Phylogenetic analyses divided H5 HPAIVs isolated in Japan in the winter of 2021&nda...
Source: Viruses - February 26, 2024 Category: Virology Authors: Junki Mine Yoshihiro Takadate Asuka Kumagai Saki Sakuma Ryota Tsunekuni Kohtaro Miyazawa Yuko Uchida Tags: Brief Report Source Type: research

Effect of Enteromorpha polysaccharides on gut-lung axis in mice infected with H5N1 influenza virus
Virology. 2024 Feb 17;593:110031. doi: 10.1016/j.virol.2024.110031. Online ahead of print.ABSTRACTEnteromorpha polysaccharides (EPPs) have been reported to have antiviral and anti-inflammatory properties. To explore the effect of EPPs on H5N1-infected mice, mice were pretreated with EPPs before being infected with the H5N1 influenza virus intranasally. H5N1 infection resulted in body-weight loss, pulmonary and intestinal damage, and an imbalance of gut microbiota in mice. As a result of the inclusion of EPPs, the body weight of mice recovered and pathological damage to the lung and intestine was reduced. EPPs also diminish...
Source: Virology - February 24, 2024 Category: Virology Authors: Yanyi Huang Peiyang Zhang Shuyi Han Bin Hu Qingxun Zhang Hongxuan He Source Type: research

Progress of Influenza Viruses and Inhibitors
Curr Med Chem. 2024 Feb 15. doi: 10.2174/0109298673268314231204061224. Online ahead of print.ABSTRACTInfluenza is an acute respiratory disease caused by influenza viruses. It has the characteristics of fast transmission and strong infectivity, and it does great harm to human health and survival. It is estimated that the seasonal influenza epidemics every year will cause about one billion cases of infections and hundreds of thousands of deaths worldwide, while influenza A virus is the leading cause of infection and death. Currently, the main drugs used in clinics to treat influenza viruses are neuraminidase inhibitors, and ...
Source: Current Medicinal Chemistry - February 16, 2024 Category: Chemistry Authors: Yuchen Xiao Jianping Yong Shaoji Lu Canzhong Lu Ruiwen Huang Source Type: research

Progress of Influenza Viruses and Inhibitors
Curr Med Chem. 2024 Feb 15. doi: 10.2174/0109298673268314231204061224. Online ahead of print.ABSTRACTInfluenza is an acute respiratory disease caused by influenza viruses. It has the characteristics of fast transmission and strong infectivity, and it does great harm to human health and survival. It is estimated that the seasonal influenza epidemics every year will cause about one billion cases of infections and hundreds of thousands of deaths worldwide, while influenza A virus is the leading cause of infection and death. Currently, the main drugs used in clinics to treat influenza viruses are neuraminidase inhibitors, and ...
Source: Current Medicinal Chemistry - February 16, 2024 Category: Chemistry Authors: Yuchen Xiao Jianping Yong Shaoji Lu Canzhong Lu Ruiwen Huang Source Type: research

Highly Pathogenic Avian Influenza A(H5N1) Virus Clade 2.3.4.4b in Domestic Ducks, Indonesia, 2022
H. Wibawa et al. (Source: Emerging Infectious Diseases Journal)
Source: Emerging Infectious Diseases Journal - February 13, 2024 Category: Infectious Diseases Source Type: research

Recent Changes in Patterns of Mammal Infection with Highly Pathogenic Avian Influenza A(H5N1) Virus Worldwide
P. I. Plaza et al. (Source: Emerging Infectious Diseases Journal)
Source: Emerging Infectious Diseases Journal - February 12, 2024 Category: Infectious Diseases Source Type: research

Viruses, Vol. 16, Pages 221: Enzootic Circulation, Massive Gull Mortality and Poultry Outbreaks during the 2022/2023 High-Pathogenicity Avian Influenza H5N1 Season in the Czech Republic
Sedlák In 2022/2023, Europe experienced its third consecutive season of high-pathogenicity avian influenza. During this period, the Czech Republic was again severely affected. For the first time, the number of culled birds approached one million, which was three times higher than in previous seasons. In parallel to the outbreaks in poultry, mass die-offs of gulls were also observed. In the present study, we performed whole-genome sequencing and phylogenetic analysis of 137 H5N1 strains collected in the Czech Republic in 2022/2023 (94.6% of all outbreaks or locations). The analysis revealed four distinct genotypes: AB...
Source: Viruses - January 31, 2024 Category: Virology Authors: Alexander Nagy Martina Star á Lenka Černíková Eli ška Kličková Ond řej Horák Lada Hofmannov á Kamil Sedl ák Tags: Article Source Type: research

Incursion of Highly Pathogenic Avian Influenza A(H5N1) Clade 2.3.4.4b Virus, Brazil, 2023
We report 4 highly pathogenic avian influenza A(H5N1) clade 2.3.4.4.b viruses in samples collected during June 2023 from Royal terns and Cabot's terns in Brazil. Phylodynamic analysis revealed viral movement from Peru to Brazil, indicating a concerning spread of this clade along the Atlantic Americas migratory bird flyway.PMID:38290826 | DOI:10.3201/eid3003.231157 (Source: Emerging Infectious Diseases)
Source: Emerging Infectious Diseases - January 30, 2024 Category: Infectious Diseases Authors: Andreina Carvalho de Ara újo Laura Morais Nascimento Silva Andrew Yong Cho M árcio Repenning Deyvid Amgarten Ana Paula de Moraes Fernanda Malta Michael Miller Erick G Dorlass Soledad Palameta Daniele Bruna L Oliveira Jansen de Ara újo Clarice Weis Arns Source Type: research

Incursion of Highly Pathogenic Avian Influenza A(H5N1) Clade 2.3.4.4b Virus, Brazil, 2023
A. de Ara újo et al. (Source: Emerging Infectious Diseases Journal)
Source: Emerging Infectious Diseases Journal - January 30, 2024 Category: Infectious Diseases Source Type: research

Multiplex Detection of RNA Viruses Based on Ligation Reaction and Universal PCR Amplification
Curr Microbiol. 2024 Jan 23;81(3):75. doi: 10.1007/s00284-023-03582-9.ABSTRACTTo detect several RNA viruses simultaneously, a method based on multiplex ligation reaction combined with multiplex qPCR or multiplex PCR+capillary electrophoresis was established to detect four RNA viruses: human immunodeficiency virus (HIV), hepatitis C (HCV), influenza A virus (IAV) H1N1 and H5N1. The experimental conditions including ligation probe concentration, annealing procedure, ligation temperature and ligase dosage were optimized intensively. We found that the specificity of the ligation reaction was affected by the probe concentration...
Source: Current Microbiology - January 23, 2024 Category: Microbiology Authors: Lijun Qian Junhua Xiao Kai Li Yuxun Zhou Source Type: research