TWiV 1105: All the T and B in China
TWiV reviews influenza H5N1 in North American cows and in birds throughout New York City, polio health emergency extended, ChatGPT to control vaccine hesitancy, increasing viral hepatitis worldwide, dengue public health alert in Puerto Rico, cherry trees drowning in Washington DC, death of iron lung Paul, origin and dispersal history of hepatitis B virus in Eastern Eurasia, and antibody-independent protection against heterologous SARS-CoV-2 challenge. Hosts: Vincent Racaniello, Alan Dove, Rich Condit, and Kathy Spindler Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links fo...
Source: This Week in Virology - MP3 Edition - April 14, 2024 Category: Virology Authors: Vincent Racaniello Source Type: podcasts
AI hears hidden X factor in zebra finch love songs
In this episode:00:48 How mysterious skyrmions could power next-generation computersSkyrmions are tiny whirlpools of magnetic spin that some researchers believe have useful properties that could unlock new kinds of computing. However getting skyrmions to perform useful computational tasks has been tricky. Now researchers have developed a method to create and manipulate skyrmions in a way that is compatible with existing computing technology, allowing them to read and write data at a fraction of the energy cost of conventional systems. The team think this shows that skyrmions could be a viable part of the next generation of...
Source: Nature Podcast - March 20, 2024 Category: Science Authors: Springer Nature Limited Source Type: podcasts
TWiV 1067: Heads or tails, you win a phage lunch
On this all-bacteriophage episode, TWiV explains the ‘vampire phage’, and and how mammalian cells internalize phage particles and utilize them to enhance cell growth and survival. Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, Rich Condit, and Jolene Ramsey Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode MicrobeTV Discord Server MicrobeTV store at Cafepress Global Scholar Travel Awards (ASV) Research assistant position in Rosenfeld Lab CBER/FDA (pdf) The New City by Dickson Despommier Gerd Sutter passes (LMU) Avian influenza A (H5...
Source: This Week in Virology - MP3 Edition - December 3, 2023 Category: Virology Authors: Vincent Racaniello Source Type: podcasts
TWiV 1053: Bird flu in Baltimore
From the Centers for Excellence in Influenza Research and Response meeting in Baltimore, Vincent speaks with Ron Fouchier, Rafael Medina, and Louse Moncla about recent changes in the epidemiology of avian H5N1 influenza virus and the threat to humans and other animals. Host: Vincent Racaniello Guests: Ron Fouchier, Rafael Medina, and Louise Moncla Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode MicrobeTV Discord Server MicrobeTV store at Cafepress Spike shirts at vaccinated.us (promo code Microbetv) Research assistant position in Rosenfeld Lab CBER/...
Source: This Week in Virology - MP3 Edition - October 15, 2023 Category: Virology Authors: Vincent Racaniello Source Type: podcasts
TWiV 1043: Marion Koopmans on COVID-19, Mpox, H5N1, polio and One Health
From the European Society for Clinical Virology meeting in Milan, Vincent speaks with Marion Koopmans about COVID-19, Mpox, H5N1 and polio, and the promise of a One Health approach to prevent outbreaks, epidemics, and pandemics. Host: Vincent Racaniello Guest: Marion Koopmans Click arrow to play Download TWiV 1043 (45 MB .mp3, 62 min) Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode MicrobeTV Discord Server MicrobeTV store at Cafepress Research assistant position in Rosenfeld Lab CBER/FDA (pdf) SARS-CoV-2 variants in Rotterdam wastewater (Sci Tot Envi...
Source: This Week in Virology - MP3 Edition - September 10, 2023 Category: Virology Authors: Vincent Racaniello Source Type: podcasts
TWiV 1025: Clinical update with Dr. Daniel Griffin
In his weekly clinical update, Dr. Griffin discusses the new risk assessment for the H5N1 avian flu viruses, the development of monoclonal antibody-based blocking ELISA for detecting SARS-CoV-2 exposure in animals, repeated antibiotic exposure and risk of hospitalization and death following COVID-19 infection, COVID-19 rebound study: a prospective cohort study to evaluate viral and symptom rebound differences in participants treated with Nirmatrelvir plus Ritonavir versus untreated controls, exaggerated blood pressure elevation in response to orthostatic challenge a post-acute sequelae of SARS-CoV-2 infection (PASC) after ...
Source: This Week in Virology - MP3 Edition - July 15, 2023 Category: Virology Authors: Vincent Racaniello Source Type: podcasts
TWiV 1013: Bird flu around the world
TWiV reviews remarkable changes in the epidemiology of avian H5N1 influenza virus leading to previously uninfected areas, involvement of previously unaffected wild birds, and devastating outbreaks in farmed poultry, and isolation of a monoclonal antibody against the influenza virus neuraminidase that inhibits infection with a wide range of A and B isolates. Hosts: Vincent Racaniello, Alan Dove, Rich Condit, Kathy Spindler, and Angela Mingarelli Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode Register for ASV 2023 Research assistant position at FDA (pd...
Source: This Week in Virology - MP3 Edition - June 4, 2023 Category: Virology Authors: Vincent Racaniello Source Type: podcasts
TWiV 983: One flu vaccine for them all with Scott Hensley
Scott returns to TWiV to explain the development of an experimental mRNA vaccine that encodes hemagglutinin antigens against all known influenza A virus subtypes and influenza B virus lineages, and why he is worried about avian H5N1 influenza virus. Hosts: Vincent Racaniello, Dickson Despommier, and Brianne Barker Guest: Scott Hensley Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode •Research assistant position at FDA (pdf) •Register for ASV 2023 •MicrobeTV Discord Server •Multivalent influenza mRNA vaccine (Science) •Influenza virus mRNA v...
Source: This Week in Virology - MP3 Edition - February 12, 2023 Category: Virology Authors: Vincent Racaniello Source Type: podcasts
TWiV 982: Clinical update with Dr. Daniel Griffin
In his weekly clinical update Dr. Griffin discusses the consistency of COVID-19 trial preprints with published reports and impact for decision making, the negative effect of preexisting immunity on Influenza vaccine responses transcends the impact of vaccine formulation type and vaccination history, highly pathogenic avian influenza A(H5N1) virus infection in farmed minks in Spain, Peru confirms H5N1 avian flu in marine mammals, prior vaccination enhances immune responses during SARS-CoV-2 breakthrough infection with early activation of memory T cells followed by production of potent neutralizing antibodies, bacillu...
Source: This Week in Virology - MP3 Edition - February 11, 2023 Category: Virology Authors: Vincent Racaniello Source Type: podcasts
TWiV 777: SARS-CoV-2 fitness with Ron Fouchier
Ron Fouchier explains why increased transmission of SARS-CoV-2-variants has not been demonstrated, and their ability to displace ancestral variants is due to greater fitness, much like influenza virus antigenic variation leads to better fitness and replacement of previously circulating variants. Hosts: Vincent Racaniello, Kathy Spindler, and Brianne Barker Guest: Ron Fouchier Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode Ron Fouchier on TWiV 177, 291, 557 Mutations driving H5N1 airborne transmission in ferrets (Cell) SARS-CoV and SARS-CoV-2 transmission among ...
Source: This Week in Virology - MP3 Edition - July 8, 2021 Category: Virology Authors: Vincent Racaniello Source Type: podcasts
TWiV 756: Precluding problematic polio prophylaxis
TWiV returns to the 2012 brouhaha over transmission experiments with avian H5N1 influenza virus, re-examines the claim of SARS-CoV-2 RNA integration into human DNA, and reviews the engineering and testing of a genetically stable version of the attenuated type 2 Sabin poliovirus vaccine. Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, Rich Condit, and Amy Rosenfeld Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode ASV vaccine town halls 3:16 First smallpox vaccine day Revised masking and distancing (CDC) Science vs Spin (Sandman) Artifactual SARS-CoV-2 in...
Source: This Week in Virology - MP3 Edition - May 16, 2021 Category: Virology Authors: Vincent Racaniello Source Type: podcasts
TWiV 396: Influenza viruses with Peter Palese
Host: Vincent Racaniello Guest: Peter Palese Vincent speaks with Peter Palese about his illustrious career in virology, from early work on neuraminidases to universal influenza virus vaccines. Become a patron of TWiV! Links for this episode Palese Laboratory Pig kidney neuraminidase (Hoppe Seylers Z Physiol Chem) DNAse in cytoplasmic DNA virus (Virology) Inhibitor of influenza virus neuraminidase (Virology) Influenza neuraminidase defective mutants (Virology) Swine influenza virus of 1976 RNA pattern (Nature) 1977 influenza H1N1 similar to 1950s strains (Nature) H5N1 influenza: Facts, not fear (PNAS) Influenza HA ...
Source: This Week in Virology - MP3 Edition - July 3, 2016 Category: Virology Authors: Vincent Racaniello Source Type: podcasts
TWiV 298: MV-NIS de myelo
Hosts: Vincent Racaniello, Alan Dove, Rich Condit, and Kathy Spindler
The TWiV gang answer follow-up questions about the Ebola virus outbreak in West Africa, then discuss treatment of disseminated multiple myeloma with oncolytic measles virus.
Links for this episode
Use of unregistered interventions for Ebola virus disease (WHO)
Response to anthrax and H5N1 incidents (CDC)
Remission of disseminated cancer after treatment with oncolytic measles virus (Mayo Clin Proc)
New viruses for cancer therapy (Nat Rev Micro)
Cattaneo on TWiV
Image credit
Letters read&nb...
Source: This Week in Virology - MP3 Edition - August 17, 2014 Category: Virology Authors: Vincent Racaniello Source Type: podcasts
