Highly pathogenic avian influenza A(H5N1) virus infection in foxes with PB2-M535I identified as a novel mammalian adaptation, Northern Ireland, July 2023
We report cases of mammalian infection with highly pathogenic avian influenza (HPAI) virus A(H5N1) clade 2.3.4.4b in Northern Ireland. Two common gulls (Larus canus) and two red fox kits (Vulpes vulpes), were found dead in close vicinity. Comparison of viral whole genome sequences obtained from the animals identified a novel mammalian adaptation, PB2-M535I. Analysis of genetic sequences from other recent mammalian infections shows that this mutation has arisen on at least five occasions in three European countries since April 2023. (Source: Eurosurveillance)
Source: Eurosurveillance - October 19, 2023 Category: Infectious Diseases Authors: Paula Lagan, Robyn McKenna, Salam Baleed, Bob Hanna, Jason Barley, Shirley McConnell, Anastasia Georgaki, Tarja Sironen, Ari Kauppinen, Tuija Gadd, Erika Lindh, Niina Ikonen, Michael J McMenamy and Ken Lemon Source Type: research
Utility of glutaraldehyde-fixed turkey red blood cells for influenza virus detection after 18 months of storage
J Virol Methods. 2023 Sep 30:114830. doi: 10.1016/j.jviromet.2023.114830. Online ahead of print.ABSTRACTTurkey red blood cells (tRBCs) are an essential reagent used in the laboratory diagnosis of influenza viruses. Fresh tRBCs when stored at 4 °C have a shelf life of less than a week. Previous studies have shown the utility of glutaraldehyde-fixed tRBCs, with an increased shelf life, for use in hemagglutination (HA) assays. In the present study we report their functionality after storage for 18 months, at -80 °C. Three influenza A subtypes, namely, H3N2, H1N1 and H5N1, were used in the study. Hemagglutination assay was p...
Source: Journal of Virological Methods - October 2, 2023 Category: Virology Authors: Shailesh D Pawar Deeksha S Tare Sadhana S Kode Sachin S Keng Source Type: research
Utility of glutaraldehyde-fixed turkey red blood cells for influenza virus detection after 18 months of storage
J Virol Methods. 2023 Sep 30:114830. doi: 10.1016/j.jviromet.2023.114830. Online ahead of print.ABSTRACTTurkey red blood cells (tRBCs) are an essential reagent used in the laboratory diagnosis of influenza viruses. Fresh tRBCs when stored at 4 °C have a shelf life of less than a week. Previous studies have shown the utility of glutaraldehyde-fixed tRBCs, with an increased shelf life, for use in hemagglutination (HA) assays. In the present study we report their functionality after storage for 18 months, at -80 °C. Three influenza A subtypes, namely, H3N2, H1N1 and H5N1, were used in the study. Hemagglutination assay was p...
Source: Journal of Virological Methods - October 2, 2023 Category: Virology Authors: Shailesh D Pawar Deeksha S Tare Sadhana S Kode Sachin S Keng Source Type: research
Utility of glutaraldehyde-fixed turkey red blood cells for influenza virus detection after 18 months of storage
J Virol Methods. 2023 Sep 30:114830. doi: 10.1016/j.jviromet.2023.114830. Online ahead of print.ABSTRACTTurkey red blood cells (tRBCs) are an essential reagent used in the laboratory diagnosis of influenza viruses. Fresh tRBCs when stored at 4 °C have a shelf life of less than a week. Previous studies have shown the utility of glutaraldehyde-fixed tRBCs, with an increased shelf life, for use in hemagglutination (HA) assays. In the present study we report their functionality after storage for 18 months, at -80 °C. Three influenza A subtypes, namely, H3N2, H1N1 and H5N1, were used in the study. Hemagglutination assay was p...
Source: Journal of Virological Methods - October 2, 2023 Category: Virology Authors: Shailesh D Pawar Deeksha S Tare Sadhana S Kode Sachin S Keng Source Type: research
Utility of glutaraldehyde-fixed turkey red blood cells for influenza virus detection after 18 months of storage
J Virol Methods. 2023 Sep 30:114830. doi: 10.1016/j.jviromet.2023.114830. Online ahead of print.ABSTRACTTurkey red blood cells (tRBCs) are an essential reagent used in the laboratory diagnosis of influenza viruses. Fresh tRBCs when stored at 4 °C have a shelf life of less than a week. Previous studies have shown the utility of glutaraldehyde-fixed tRBCs, with an increased shelf life, for use in hemagglutination (HA) assays. In the present study we report their functionality after storage for 18 months, at -80 °C. Three influenza A subtypes, namely, H3N2, H1N1 and H5N1, were used in the study. Hemagglutination assay was p...
Source: Journal of Virological Methods - October 2, 2023 Category: Virology Authors: Shailesh D Pawar Deeksha S Tare Sadhana S Kode Sachin S Keng Source Type: research
Utility of glutaraldehyde-fixed turkey red blood cells for influenza virus detection after 18 months of storage
J Virol Methods. 2023 Sep 30:114830. doi: 10.1016/j.jviromet.2023.114830. Online ahead of print.ABSTRACTTurkey red blood cells (tRBCs) are an essential reagent used in the laboratory diagnosis of influenza viruses. Fresh tRBCs when stored at 4 °C have a shelf life of less than a week. Previous studies have shown the utility of glutaraldehyde-fixed tRBCs, with an increased shelf life, for use in hemagglutination (HA) assays. In the present study we report their functionality after storage for 18 months, at -80 °C. Three influenza A subtypes, namely, H3N2, H1N1 and H5N1, were used in the study. Hemagglutination assay was p...
Source: Journal of Virological Methods - October 2, 2023 Category: Virology Authors: Shailesh D Pawar Deeksha S Tare Sadhana S Kode Sachin S Keng Source Type: research
Utility of glutaraldehyde-fixed turkey red blood cells for influenza virus detection after 18 months of storage
J Virol Methods. 2023 Sep 30:114830. doi: 10.1016/j.jviromet.2023.114830. Online ahead of print.ABSTRACTTurkey red blood cells (tRBCs) are an essential reagent used in the laboratory diagnosis of influenza viruses. Fresh tRBCs when stored at 4 °C have a shelf life of less than a week. Previous studies have shown the utility of glutaraldehyde-fixed tRBCs, with an increased shelf life, for use in hemagglutination (HA) assays. In the present study we report their functionality after storage for 18 months, at -80 °C. Three influenza A subtypes, namely, H3N2, H1N1 and H5N1, were used in the study. Hemagglutination assay was p...
Source: Journal of Virological Methods - October 2, 2023 Category: Virology Authors: Shailesh D Pawar Deeksha S Tare Sadhana S Kode Sachin S Keng Source Type: research
Utility of glutaraldehyde-fixed turkey red blood cells for influenza virus detection after 18 months of storage
J Virol Methods. 2023 Sep 30:114830. doi: 10.1016/j.jviromet.2023.114830. Online ahead of print.ABSTRACTTurkey red blood cells (tRBCs) are an essential reagent used in the laboratory diagnosis of influenza viruses. Fresh tRBCs when stored at 4 °C have a shelf life of less than a week. Previous studies have shown the utility of glutaraldehyde-fixed tRBCs, with an increased shelf life, for use in hemagglutination (HA) assays. In the present study we report their functionality after storage for 18 months, at -80 °C. Three influenza A subtypes, namely, H3N2, H1N1 and H5N1, were used in the study. Hemagglutination assay was p...
Source: Journal of Virological Methods - October 2, 2023 Category: Virology Authors: Shailesh D Pawar Deeksha S Tare Sadhana S Kode Sachin S Keng Source Type: research
Utility of glutaraldehyde-fixed turkey red blood cells for influenza virus detection after 18 months of storage
J Virol Methods. 2023 Sep 30:114830. doi: 10.1016/j.jviromet.2023.114830. Online ahead of print.ABSTRACTTurkey red blood cells (tRBCs) are an essential reagent used in the laboratory diagnosis of influenza viruses. Fresh tRBCs when stored at 4 °C have a shelf life of less than a week. Previous studies have shown the utility of glutaraldehyde-fixed tRBCs, with an increased shelf life, for use in hemagglutination (HA) assays. In the present study we report their functionality after storage for 18 months, at -80 °C. Three influenza A subtypes, namely, H3N2, H1N1 and H5N1, were used in the study. Hemagglutination assay was p...
Source: Journal of Virological Methods - October 2, 2023 Category: Virology Authors: Shailesh D Pawar Deeksha S Tare Sadhana S Kode Sachin S Keng Source Type: research
Utility of glutaraldehyde-fixed turkey red blood cells for influenza virus detection after 18 months of storage
J Virol Methods. 2023 Sep 30:114830. doi: 10.1016/j.jviromet.2023.114830. Online ahead of print.ABSTRACTTurkey red blood cells (tRBCs) are an essential reagent used in the laboratory diagnosis of influenza viruses. Fresh tRBCs when stored at 4 °C have a shelf life of less than a week. Previous studies have shown the utility of glutaraldehyde-fixed tRBCs, with an increased shelf life, for use in hemagglutination (HA) assays. In the present study we report their functionality after storage for 18 months, at -80 °C. Three influenza A subtypes, namely, H3N2, H1N1 and H5N1, were used in the study. Hemagglutination assay was p...
Source: Journal of Virological Methods - October 2, 2023 Category: Virology Authors: Shailesh D Pawar Deeksha S Tare Sadhana S Kode Sachin S Keng Source Type: research
Mass Mortality Event in South American Sea Lions ( < em > Otaria flavescens < /em > ) Correlated to Highly Pathogenic Avian Influenza (HPAI) H5N1 Outbreak in Chile
Vet Q. 2023 Sep 28:1-13. doi: 10.1080/01652176.2023.2265173. Online ahead of print.ABSTRACTIn Chile, since January 2023, a sudden and pronounced increase in strandings and mortality has been observed among South American (SA) sea lions (Otaria flavescens), prompting significant concern. Simultaneously, an outbreak of highly pathogenic avian influenza H5N1 (HPAIV H5N1) in avian species has emerged since December 2022. To investigate the cause of this unexpected mortality, we conducted a comprehensive epidemiological and pathologic study. One hundred sixty-nine SA sea lions were sampled to ascertain their HPAIV H5N1 status, ...
Source: Veterinary Quarterly - September 28, 2023 Category: Veterinary Research Authors: Mauricio Ulloa Antonio Fern ández Naomi Ariyama Ana Colom-Rivero Carlos Rivera Paula Nu ñez Paola Sanhueza Magdalena Johow Hugo Araya Juan Carlos Torres Paola Gomez Gabriela Mu ñoz Bel én Agüero Ra úl Alegría Rafael Medina Victor Neira Eva Sierra Source Type: research
Changing bird migrations threaten to bring new infectious diseases to humans
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