What is allopurinol "failure" and what should we do about it?
J Rheumatol. 2024 Mar 15:jrheum.2024-0144. doi: 10.3899/jrheum.2024-0144. Online ahead of print.ABSTRACTAllopurinol is the most widely used urate-lowering medication world-wide. However, allopurinol "failure" is frequently observed in clinical practice. In this review, we provide a framework for assessing allopurinol "failure", which includes failure of allopurinol to control serum urate concentrations, failure of allopurinol to control clinical symptoms, and failure of allopurinol due to an adverse drug reaction. Understanding the causes of allopurinol "failure" underpins the approach required to turn "failure" into "succ...
Source: J Rheumatol - March 15, 2024 Category: Rheumatology Authors: Lisa K Stamp Nicola Dalbeth Source Type: research
What is allopurinol "failure" and what should we do about it?
J Rheumatol. 2024 Mar 15:jrheum.2024-0144. doi: 10.3899/jrheum.2024-0144. Online ahead of print.ABSTRACTAllopurinol is the most widely used urate-lowering medication world-wide. However, allopurinol "failure" is frequently observed in clinical practice. In this review, we provide a framework for assessing allopurinol "failure", which includes failure of allopurinol to control serum urate concentrations, failure of allopurinol to control clinical symptoms, and failure of allopurinol due to an adverse drug reaction. Understanding the causes of allopurinol "failure" underpins the approach required to turn "failure" into "succ...
Source: Journal of Rheumatology - March 15, 2024 Category: Rheumatology Authors: Lisa K Stamp Nicola Dalbeth Source Type: research
What is allopurinol "failure" and what should we do about it?
J Rheumatol. 2024 Mar 15:jrheum.2024-0144. doi: 10.3899/jrheum.2024-0144. Online ahead of print.ABSTRACTAllopurinol is the most widely used urate-lowering medication world-wide. However, allopurinol "failure" is frequently observed in clinical practice. In this review, we provide a framework for assessing allopurinol "failure", which includes failure of allopurinol to control serum urate concentrations, failure of allopurinol to control clinical symptoms, and failure of allopurinol due to an adverse drug reaction. Understanding the causes of allopurinol "failure" underpins the approach required to turn "failure" into "succ...
Source: J Rheumatol - March 15, 2024 Category: Rheumatology Authors: Lisa K Stamp Nicola Dalbeth Source Type: research
What Is Allopurinol Failure and What Should We Do About It?
J Rheumatol. 2024 Apr 1:jrheum.2024-0144. doi: 10.3899/jrheum.2024-0144. Online ahead of print.ABSTRACTAllopurinol is the most widely used urate-lowering medication worldwide. However, allopurinol failure is frequently observed in clinical practice. In this review, we provide a framework for assessing allopurinol failure, which includes failure of allopurinol to control serum urate concentrations, failure of allopurinol to control clinical symptoms, and failure of allopurinol due to an adverse drug reaction. Understanding the causes of allopurinol failure underpins the approach required to turn failure into success in gout...
Source: Journal of Rheumatology - March 15, 2024 Category: Rheumatology Authors: Lisa K Stamp Nicola Dalbeth Source Type: research
What Is Allopurinol Failure and What Should We Do About It?
J Rheumatol. 2024 Apr 1:jrheum.2024-0144. doi: 10.3899/jrheum.2024-0144. Online ahead of print.ABSTRACTAllopurinol is the most widely used urate-lowering medication worldwide. However, allopurinol failure is frequently observed in clinical practice. In this review, we provide a framework for assessing allopurinol failure, which includes failure of allopurinol to control serum urate concentrations, failure of allopurinol to control clinical symptoms, and failure of allopurinol due to an adverse drug reaction. Understanding the causes of allopurinol failure underpins the approach required to turn failure into success in gout...
Source: J Rheumatol - March 15, 2024 Category: Rheumatology Authors: Lisa K Stamp Nicola Dalbeth Source Type: research
