Prednisolone Versus Colchicine for Acute Gout in Primary Care: statistical analysis plan for the pragmatic, multicenter, randomized, and double-blinded COPAGO non-inferiority trial
DiscussionThe trial will provide evidence from a direct comparison of colchicine and prednisolone regarding their efficacy of pain reduction in acute gout patients of primary care and to indicate possible safety signals.Trial registrationClinicalTrials.gov Identifier: NCT05698680 first posted on January 26, 2023 (retrospectively registered). (Source: Trials)
Source: Trials - April 3, 2024 Category: Research Source Type: clinical trials
A Phase Ib Clinical Trial of Peguricase for Injection With Methotrexate in Patients With Uncontrolled Gout.
Conditions: Gout Interventions: Drug: SIBP-R002; Drug: SIBP-R002; Drug: SIBP-R002; Drug: Methotrexate Sponsors: Shanghai Institute Of Biological Products; First Affiliated Hospital Bengbu Medical College; The First Affiliated Hospital of Henan University of Science and Technology; Chengdu Fifth People ' s Hospital Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 7, 2024 Category: Research Source Type: clinical trials
A Study to Investigate the Pharmacokinetic/Pharmacodynamic Characteristics of IBI128(A New Xanthine Oxidase Inhibitor)
Conditions: Gout Arthritis Interventions: Drug: dose-5 group; Drug: dose-1 group; Drug: dose-2 group; Drug: dose-4 group; Drug: dose-3 group Sponsors: Innovent Biologics (Suzhou) Co. Ltd. Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - February 26, 2024 Category: Research Source Type: clinical trials
Extension Study of ABP-671 in Participants With Gout
Conditions: Gout Interventions: Drug: ABP-671; Drug: Allopurinol Sponsors: Jiangsu Atom Bioscience and Pharmaceutical Co., Ltd. Enrolling by invitation (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - February 26, 2024 Category: Research Source Type: clinical trials
Treatment of Topical Ketorolac Gel in Acute Gouty Flare
Conditions: Acute Gouty Arthritis; Acute Pain; Gout Flare Interventions: Drug: Ketorolac Tromethamine 15 MG/ML; Drug: Ketorolac Tromethamine Sponsors: Novilla Pharmaceuticals Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - February 23, 2024 Category: Research Source Type: clinical trials
A Study of SSGJ-613 in Gout Subjects Initiating Urate-Lowering Treatment.
Conditions: Gout Arthritis Interventions: Drug: Recombinant Anti-IL-1 β Humanized Monoclonal Antibody Injection 100 mg; Drug: Recombinant Anti-IL-1β Humanized Monoclonal Antibody Injection 200 mg; Drug: Colchicine 0.5 mg Sponsors: Sunshine Guojian Pharmaceutical (Shanghai) Co., Ltd. Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - February 21, 2024 Category: Research Source Type: clinical trials
A Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of Oral ABP-745 Administration in Healthy Volunteers
Conditions: Gout Interventions: Drug: ABP-745; Drug: Placebo Sponsors: Jiangsu Atom Bioscience and Pharmaceutical Co., Ltd. Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - February 14, 2024 Category: Research Source Type: clinical trials
Prevalence of Musculoskeletal Complaints in Nursing Home Residents
Conditions: Rheumatoid Arthritis; Rheumatic Diseases; Musculoskeletal Diseases; Musculoskeletal Diseases or Conditions; Gout; Degenerative Joint Disease; Orthopedic Disorder; Arthritis; Polyarthritis; Musculoskeletal Pain; Arthrosis Sponsors: Maastricht University Medical Center Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - February 1, 2024 Category: Research Source Type: clinical trials
A Trial to Investigate the Non-inferiority of Pegloticase Administered Every 4 Weeks (Q4W) With MTX Compared With Every 2 Weeks (Q2W) With MTX in Participants With Uncontrolled Refractory Gout
Conditions: Gout Interventions: Biological: Pegloticase; Drug: Methotrexate Sponsors: Horizon Therapeutics Ireland DAC Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 29, 2024 Category: Research Source Type: clinical trials
The Remote Monitoring of Gout Feasibility Study
Conditions: Gout Interventions: Device: Self-management for patients with gout Sponsors: Diakonhjemmet Hospital Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 18, 2024 Category: Research Source Type: clinical trials
The Effects of Limb Elevation During Gout Flare Episodes
Conditions: Gout Flare Interventions: Procedure: limb elevation Sponsors: Thammasat University Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 15, 2024 Category: Research Source Type: clinical trials
PK Effects of SHR4640 on Repaglinide and Midazolam, and the Impact of SHR4640 on QT Interval
Conditions: Gout and Hyperuricemia Interventions: Drug: repaglinide; midazolam; SHR4640; Drug: repaglinide; midazolam; SHR4640; SHR4640 placebo; Drug: repaglinide; midazolam; SHR4640 placebo Sponsors: Jiangsu HengRui Medicine Co., Ltd. Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 9, 2024 Category: Research Source Type: clinical trials
Novel Biomarkers for Early Renal Injury in Children With Sepsis
This study is an observational studie which have no intervention Sponsors: Xinhua Hospital, Shanghai Jiao Tong University School of Medicine Active, not recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 9, 2024 Category: Research Source Type: clinical trials
Effect of Tigulixostat on the Pharmacokinetics of Theophylline
Conditions: Gout; Hyperuricemia Interventions: Drug: Tigulixostat; Drug: Theophylline Sponsors: LG Chem Completed (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 3, 2024 Category: Research Source Type: clinical trials
UR+AIMS Gout Wearable Skin Uric Acid Monitor Study
Conditions: Gout Interventions: Device: Uric Acid and Metabolite Monitor System (UR+AIMS) skin patch Sponsors: University of California, Los Angeles; National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 1, 2024 Category: Research Source Type: clinical trials
