Genetic and Risk Factors in Exfoliation Glaucoma Patients
Conditions: Glaucoma Capsulare; Genetic Predisposition to Disease; Risk Reduction Interventions: Other: No intervention Sponsors: G öteborg University Completed (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - February 1, 2024 Category: Research Source Type: clinical trials
Genotype-phenotype Characterization Study on Genetic Diseases With Immune and Neurological Dysfunctions
Conditions: Genetic Diseases; Immune Dysfunction; Neurological Disease; Autoimmune Diseases Interventions: Other: Biological Samples Sponsors: Imagine Institute Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - February 1, 2024 Category: Research Source Type: clinical trials
A Comparative Analysis of Speech Perception Between Cochlear Implant Patients and DFNB9 Patients Receiving Gene Therapy
Conditions: Hearing Loss; Genetic Disease; Speech Perception Sponsors: Eye& ENT Hospital of Fudan University; Shanghai Rehabilitation Institute for the Exceptional Children Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - February 1, 2024 Category: Research Source Type: clinical trials
A Clinical Study Evaluating the Safety, Tolerability and Initial Efficacy of SKG0106 Intravitreal Injection in Diabetic Macular Edema (DME) Patients
Conditions: Diabetic Macular Edema Interventions: Genetic: SKG0106 intravitreal injection dose level 1, 2 or 3 Sponsors: Wang Min; Lanyue Biotech (Hangzhou) Co., Ltd. Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - February 1, 2024 Category: Research Source Type: clinical trials
Gut Microbiota Dysbiosis in Lupus Nephritis
Conditions: Gut Microbiota Dysbiosis in Lupus Nepheritis Interventions: Genetic: DNA extraction and PCR amplification Sponsors: Hager Zanaty Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 30, 2024 Category: Research Source Type: clinical trials
Open-label, Dose Escalation Study of Safety and Preliminary Efficacy of TN-401 in Adults With PKP2 Mutation-associated ARVC
Conditions: Arrhythmogenic Right Ventricular Cardiomyopathy Interventions: Genetic: TN-401 Sponsors: Tenaya Therapeutics Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 29, 2024 Category: Research Source Type: clinical trials
Genetic Susceptibility to Predict Weight Loss After Bariatric Surgery
Conditions: Bariatric Surgery Candidate; Obesity, Morbid; Genetic Predisposition; Metabolic Syndrome; Weight Loss Sponsors: Institut de Recerca Biom èdica de Lleida; ISCIII Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 26, 2024 Category: Research Source Type: clinical trials
Characterization and Recognition of Genetic Diseases by Photography
Conditions: Dysmorphology; Orphan Diseases Interventions: Other: Clinical Data reuse Sponsors: Imagine Institute Completed (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 25, 2024 Category: Research Source Type: clinical trials
Modulation of SERCA2a of Intra-Myocytic Calcium Trafficking in Cardiomyopathy Secondary to Duchenne Muscular Dystrophy
Conditions: DMD-Associated Dilated Cardiomyopathy Interventions: Genetic: SRD-001 Sponsors: Sardocor Corp. Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 25, 2024 Category: Research Source Type: clinical trials
Hyperlactacidemia in Major Abdominal Surgery and Monocarboxylate Receptors
Conditions: Surgical Procedure, Unspecified; Postoperative Complications; Hyperlactatemia; Abdomen Disease Interventions: Genetic: Genetic analysis of polymorphism of membrane receptors involved in lactate transport Sponsors: Fondazione Policlinico Universitario Agostino Gemelli IRCCS Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 24, 2024 Category: Research Source Type: clinical trials
Endothelial NO Synthase Polymorphic Gene in Coronary Artery Dilation Disease
Conditions: Coronary Artery Ectasia Interventions: Diagnostic Test: The specific genetic PCR laboratory test were performed for all selected patients for eNOS SNPs Sponsors: Cairo University Completed (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 24, 2024 Category: Research Source Type: clinical trials
Safety and Efficacy of the Lentiviral Vector in Gene Therapy of Beta-thalassemia Patients
Conditions: Transfusion-dependent Beta-Thalassemia Interventions: Genetic: KL003 cell injection Drug Product Sponsors: Institute of Hematology& Blood Diseases Hospital, China; Kanglin Biotech Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 23, 2024 Category: Research Source Type: clinical trials
Positive Phase 1/2 Clinical Trial Data for an Investigational Gene Therapy for Genetic Hearing Loss to be Presented at the Association for Research in Otolaryngology 2024 MidWinter Meeting
Hearing restoration was observed within 30 days of a single administration of AK-OTOF in the initial AK-OTOF-101 study participant, the first to receive gene therapy in the United States for a genetic form of hearing loss
AK-OTOF is a gene... (Source: Drugs.com - Clinical Trials)
Source: Drugs.com - Clinical Trials - January 23, 2024 Category: Pharmaceuticals Source Type: clinical trials
The Effect of Polymorphism of the GUCY1A3 rs7692387 Gene on Cardiovascular Events After Coronary Artery Bypass Grafting.
Conditions: to Evaluate the Association of GUCY1A3 rs7692387 Gene Polymorphism Carrier on the Development of Cardiovascular Events After Coronary Artery Bypass Grafting Interventions: Genetic: coronary artery bypass grafting Sponsors: Novosibirsk Scientific Research Institute for Circulatory Pathology Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 22, 2024 Category: Research Source Type: clinical trials
A Clinical Study Evaluating the Safety and Efficacy of SKG0106 in Patients With Neovascular Age-related Macular Degeneration (nAMD)
Conditions: Neovascular Age-related Macular Degeneration Interventions: Genetic: SKG0106 One-Time Intraocular Injection Sponsors: Youxin Chen Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 19, 2024 Category: Research Source Type: clinical trials
