Development of a Neuronal Microscope
Conditions: Hepatic Carcinoma Interventions: Genetic: genetic model Sponsors: Fondazione IRCCS Ca ' Granda, Ospedale Maggiore Policlinico Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 15, 2024 Category: Research Source Type: clinical trials
Understanding, Diagnosis and Monitoring of Thyroid Hormone Action Defects
Conditions: Resistance, Thyroid Hormone Interventions: Genetic: NGS sequencing; Diagnostic Test: serological tests Sponsors: Istituto Auxologico Italiano; ASST Fatebenefratelli Sacco; Federico II University Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 13, 2024 Category: Research Source Type: clinical trials
An Adaptive Clinical Trial of BeginNGS Newborn Screening for Hundreds of Genetic Diseases by Genome Sequencing
Conditions: Genetic Disease Interventions: Genetic: BeginNGS Test Sponsors: Rady Pediatric Genomics& Systems Medicine Institute Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 12, 2024 Category: Research Source Type: clinical trials
Precision Therapy for Solid Tumors: Synergistic CDK4/6 Inhibition and Anti-VEGF Targeting LncRNA
Conditions: Cancer; Solid Tumor; Colorectal Cancer; Breast Cancer; Ovarian Cancer; Lung Cancer; Targeted Therapy; Chemotherapy; Immunotherapy; Precision Therapy Interventions: Genetic: SNP; Drug: Palbociclib 125mg; Drug: Bevacizumab Sponsors: Lebanese University; Haykel Hospital Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 12, 2024 Category: Research Source Type: clinical trials
Defining Treatment Outcomes and Genetic Architecture in Idiopathic Toe Walking*
Conditions: Idiopathic Toe Walking Interventions: Procedure: Surgery; Procedure: Serial Casting Sponsors: Shriners Hospitals for Children Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 12, 2024 Category: Research Source Type: clinical trials
Safety and Efficacy Study of NGGT001 in Bietti Crystalline Corneoretinal Dystrophy
Conditions: Bietti ' s Crystalline Dystrophy Interventions: Genetic: NGGT001 Sponsors: Xiamen Ophthalmology Center Affiliated to Xiamen University Active, not recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 11, 2024 Category: Research Source Type: clinical trials
Testing AZD9291 as Potentially Targeted Treatment in Cancers With EGFR Genetic Changes (MATCH-Subprotocol E)
Conditions: Advanced Lymphoma; Advanced Malignant Solid Neoplasm; Hematopoietic and Lymphoid Cell Neoplasm; Refractory Lymphoma; Refractory Malignant Solid Neoplasm; Refractory Multiple Myeloma Interventions: Procedure: Biopsy; Procedure: Biospecimen Collection; Procedure: Echocardiography; Procedure: Multigated Acquisition Scan; Drug: Osimertinib; Procedure: Radiologic Examination Sponsors: National Cancer Institute (NCI) Active, not recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 11, 2024 Category: Research Source Type: clinical trials
Safety and Efficacy of a Single Subretinal Injection of JWK006 Gene Therapy in Subjects With Stargardt Disease(STGD1)
Conditions: Stargardt Disease 1 Interventions: Genetic: JWK006 Sponsors: West China Hospital Active, not recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 8, 2024 Category: Research Source Type: clinical trials
Study of a Gene Therapy Treatment for Hemophilia A
Conditions: Hemophilia A Interventions: Genetic: SPK-8011 Sponsors: Spark Therapeutics, Inc. Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 7, 2024 Category: Research Source Type: clinical trials
Genetic variability to glp1 treatment
Conditions: Type 2 Diabetes; Obesity Interventions: Genetic: DNA Sequencing and Analysis; Genetic: differential expression analysis with RNA-sequencing (RNA seq) experiments Sponsors: GENGE Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 7, 2024 Category: Research Source Type: clinical trials
Whether Vaginal Microbiota Affects Pregnancy Outcomes After Embryo Transfer
Conditions: Infertility, Female; Microbial Colonization Sponsors: ShangHai Ji Ai Genetics& IVF Institute Completed (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 6, 2024 Category: Research Source Type: clinical trials
Microphthalmia, Anophthalmia, and Coloboma Genetic Epidemiology in Children
Conditions: Microphthalmia; Coloboma; Anophthalmia Sponsors: Baylor College of Medicine; National Eye Institute (NEI); National Institutes of Health (NIH) Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 5, 2024 Category: Research Source Type: clinical trials
A Safety and Efficacy Study Evaluating CS-101 in Subjects With β-Thalassemia Major
Conditions: Beta-Thalassemia Major Interventions: Genetic: CS-101 injection Sponsors: CorrectSequence Therapeutics Co., Ltd Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 4, 2024 Category: Research Source Type: clinical trials
Safety and Efficacy Study of IVB102 Injection in Subjects With X-linked Retinoschisis
Conditions: Retinoschisis; Retinal Disease; Retinal Degeneration; Eye Diseases Interventions: Genetic: IVB102 Injection; Genetic: IVB102 Injection; Genetic: IVB102 Injection Sponsors: InnoVec Biotherapeutics Inc.; Peking Union Medical College Hospital Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 1, 2024 Category: Research Source Type: clinical trials
Epcoritamab (Epcor)-Containing Combination Salvage Therapy Followed by ASCT & Epcor Consolidation in Patients With Relapsed LBCL
Conditions: DLBCL - Diffuse Large B Cell Lymphoma; High-grade B-cell Lymphoma; High Grade B-Cell Lymphoma With MYC and BCL2 or BCL6 Rearrangements; DLBCL, Nos Genetic Subtypes; High Grade B-Cell Lymphoma, Not Otherwise Specified; Follicular Large Cell Lymphoma, Relapsed; Follicular Large Cell Lymphoma Interventions: Drug: Epcoritamab Sponsors: Australasian Leukaemia and Lymphoma Group Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 1, 2024 Category: Research Source Type: clinical trials
